Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
5 Star Hotels in Panama City
1. Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
2. JW Marriott Panama
JW Marriott Panama
3. Hotel La Compañía Casco Antiguo
Hotel La Compañía Casco Antiguo
4. Sofitel Legend Casco Viejo, Panama City
Sofitel Legend Casco Viejo, Panama City
5. Hilton Panama
Hilton Panama
7. Waldorf Astoria Panama
Waldorf Astoria Panama
8. Renaissance Panama City Hotel
Renaissance Panama City Hotel
9. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
10. Hyatt Regency Panama City
Hyatt Regency Panama City
11. Bristol Panama, a Registry Collection Hotel
Bristol Panama, a Registry Collection Hotel
12. The Westin Playa Bonita Panama
The Westin Playa Bonita PanamaTop neighborhoods in Panama City
Casco Viejo
Casco Viejo's cobblestone streets tell Panama's colonial story at every turn. The golden Metropolitan Cathedral and historic theaters create a living museum vibe. Rooftop bars offer spectacular bay views while museums showcase Panama's diverse heritage. Plaza hopping rewards you with hidden architectural gems and cultural performances that bring history to life. The neighborhood serves up everything from fusion cuisine in restored mansions to traditional Panamanian dishes. Boutique hotels occupy colonial buildings with charming courtyards and personalized service. Though compact, comfortable walking shoes are essential for navigating the uneven historic streets.
Bella Vista
Bella Vista balances Panama City's sleek business side with upscale urban living. Gleaming skyscrapers along Avenida Balboa house financial headquarters while trendy spots on Calle Uruguay buzz with after-work crowds. Shop at MultiPlaza Pacific mall, visit Crown Casino, or simply stroll the waterfront promenade for stunning bay views. Getting around is a breeze with two metro stations and plentiful taxis. Dining options range from rooftop restaurants to international cuisine that won't disappoint. High-rise hotels with spectacular views cater to business travelers and tourists who appreciate modern comforts with a side of ocean breeze.
El Cangrejo
El Cangrejo pulses with modern energy around the iconic "El Tornillo" tower, where art meets business in Panama City's cosmopolitan heart. Korean BBQ aromas mingle with coffee scents from sidewalk cafes, while galleries showcase local talent beneath tropical sunshine. Colorful murals splash across office buildings as diverse cultures blend in this trendy district. The neighborhood serves up an eclectic fusion of Korean, Jewish, and Panamanian cuisines in stylish eateries and casual cafes. Modern boutique hotels and upscale business lodging dominate accommodation options. Getting around is a breeze with nearby Metro Line 1 stations, abundant taxis, and pleasantly walkable streets.
Obarrio
Obarrio dazzles with gleaming skyscrapers housing Panama City's financial powerhouses and luxury shopping. Multiplaza Pacific mall tempts with designer boutiques while the business crowd buzzes between meetings. When you're not trying your luck at local casinos, relax at a sophisticated coffeehouse or stroll the wide, clean sidewalks of Calle 50. Hotels range from international chains to boutique properties, with rates reflecting the upscale surroundings. Getting around is a breeze with excellent taxi service, frequent buses along Via España, and the Metro Line 1 connecting directly to Iglesia del Carmen station.
Punta Pacifica
Punta Pacifica's gleaming glass towers and an iconic sail-shaped skyscraper create a skyline that screams luxury with a Pacific Ocean backdrop. Stroll the waterfront promenades where swaying palms frame perfect sunset views, or duck into Multiplaza Pacific Mall to browse designer boutiques in marble-floored splendor. The neighborhood balances business and pleasure with its mix of corporate offices and upscale leisure spots. Dining here means international cuisine with ocean views at rooftop bars and hotel restaurants where reservations are smart moves. High-rise hotels and serviced apartments offer amenities like infinity pools and concierge services. Getting around is easy with abundant taxis and walkable streets, though you won't find much public transit in this polished enclave.
