5 Star Hotels in Syracuse

October 2026
16
November 2026

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This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

5 Star Hotels in Syracuse

1. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
$153
$179 total
includes taxes & fees
Nov 5 - Nov 6
Caportigia Boutique Hotel

2. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
$293
$333 total
includes taxes & fees
Nov 8 - Nov 9
Ortea Palace Hotel, Sicily, Autograph Collection

3. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
$266
$304 total
includes taxes & fees
Nov 16 - Nov 17
Grand Hotel Ortigia Siracusa

4. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
$692
$772 total
includes taxes & fees
Oct 24 - Oct 25
Grand Hotel Des Ètrangers - The Leading Hotels of the World

5. Minareto

Minareto
Syracuse
$312
$354 total
includes taxes & fees
Nov 6 - Nov 7
Minareto

6. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
$328
$372 total
includes taxes & fees
Nov 5 - Nov 6
Wellness & Spa Hotel Principe di Fitalia

7. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
$323
$366 total
includes taxes & fees
Nov 1 - Nov 2
Dimora Caiammari Luxury Hotel & Spa

8. Mangia's Brucoli, Sicily, Autograph Collection

Mangia's Brucoli, Sicily, Autograph Collection
Augusta
$179
$197 total
includes taxes & fees
Nov 8 - Nov 9
Mangia's Brucoli, Sicily, Autograph Collection

9. Il San Corrado di Noto Luxury Resort

Il San Corrado di Noto Luxury Resort
Noto
$1,270
$1,409 total
includes taxes & fees
Oct 25 - Oct 26
Il San Corrado di Noto Luxury Resort
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Top neighborhoods in Syracuse

Ortigia

Ortigia's ancient limestone streets tell 2,700 years of Mediterranean stories through every weathered stone. Greek temple ruins stand beside a stunning Baroque cathedral, while the 13th-century Castello Maniace guards this tiny island's tip. The mystical Fonte Aretusa freshwater spring creates a papyrus grove right beside the crystal-clear Ionian Sea. Waterfront trattorias serve fresh seafood and Sicilian classics while you watch fishing boats bobbing at sunset. The compact 1km island is best explored on foot through narrow medieval lanes. Historic palazzos converted to boutique hotels offer authentic stays with sea views from wrought-iron balconies.

Neapolis

Step back in time at Syracuse's Neapolis, where ancient Greek and Roman civilizations come alive through remarkable ruins. The Greek Theater carved into limestone hills offers stunning harbor views, while the Roman Amphitheater reveals gladiatorial heritage. Don't miss the Ear of Dionysius cave where whispers magically amplify, or the Paradise Quarry gardens blooming with Mediterranean flora. Getting around requires walking on uneven ancient paths, with limited bus service connecting to Syracuse center. Pack a lunch or visit the small café near the entrance since dining options are minimal. The archaeological park closes at sunset, so plan your visit during daylight hours to fully experience this extraordinary outdoor museum.

Santa Lucia

Santa Lucia delivers an epic history lesson with every step through its honey-colored streets. The ancient neighborhood showcases Greek ruins, the legendary Tomb of Archimedes, and the stunning Church of Santa Lucia alla Badia with its soaring dome. Colorful fishing boats bob in Porto Piccolo while the Ionian Sea provides a sparkling backdrop to centuries of Mediterranean heritage. Traditional Sicilian trattorias serve fresh seafood along the waterfront promenade. Stone-walled boutique guesthouses and converted palazzo B&Bs make perfect bases for exploring this walkable historic quarter. The limited public buses mean you'll mostly discover Santa Lucia's treasures on foot, which is exactly how this ancient place should be experienced.

Grottasanta

The Grottasanta neighborhood offers attractions such as Pista Ciclabile Siracusa and Ionian Sea.

Acradina

The Acradina neighborhood offers attractions such as Ionian Sea and Capuchin Quarry.

Top landmarks in Syracuse

A coastal cityscape with buildings along the waterfront, a clear blue sky, and a calm sea.
Photo by Juan Pablo Pantoja

Lungomare di Ortigia

9.4/10 (654 reviews)
Ortigia is home to Lungomare di Ortigia, so why not stop by during your stay in Syracuse.
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Ancient ruins, a sign reading "Tempio di Apollo," and a man observing the site.

Temple of Apollo

8.8/10 (692 reviews)
If you're planning a bit of sightseeing head to Temple of Apollo— just one of the monuments in Ortigia. You can also discover the museums and cathedral in the area— your sightseeing tour starts here.
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Fontane Bianche Beach

8.0/10 (189 reviews)
When the beach is calling your name, you might want to head down to Fontane Bianche Beach, located 8.5 mi (13.7 km) from central Syracuse. Enjoy the sunset by the shore at Gallina Beach, Arenella Beach, and Lungomare Tremoli Beach.
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Greek Theatre of Syracuse

9.2/10 (694 reviews)
If you're planning a bit of sightseeing head to Greek Theatre of Syracuse— just one of the monuments in Neapolis. You could also start your cultural experience by heading over to the cathedral in the area.
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Piazza del Duomo

9.6/10 (551 reviews)
Piazza del Duomo is worth passing through for a few pics when in Ortigia. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.
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Archaeological Park of Neapolis

9.0/10 (485 reviews)
If you're planning a bit of sightseeing head to Archaeological Park of Neapolis— just one of the monuments in Neapolis. You could also start your cultural experience by heading over to the cathedral in the area.
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Cathedral of Syracuse

9.4/10 (813 reviews)
If you're planning a bit of sightseeing head to Cathedral of Syracuse— just one of the monuments in Ortigia. You can also discover the cathedral and museums in the area— your sightseeing tour starts here.
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Pista Ciclabile Siracusa

10.0/10 (4 reviews)
Travelers who enjoy the great outdoors might want to go to Pista Ciclabile Siracusa, located 1 mi (1.6 km) from central Syracuse.
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