Hotels in Mesopotamia

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Check prices for these dates

Tonight
Aug 9 - Aug 10
Tomorrow
Aug 10 - Aug 11
Next weekend
Aug 14 - Aug 16
In two weeks
Aug 21 - Aug 23

Top 5 hotels in Mesopotamia at a glance

  1. To Spiti tis Sofias — Located in Kastoria. Guest rating: 10/10 — Exceptional.
  2. Limneon Resort & Spa — 5-star hotel in Kastoria. Guest rating: 9.2/10 — Wonderful.
  3. Hotel Anastassiou — 2-star hotel in Kastoria. Guest rating: 8.0/10 — Very Good.
  4. Chloe Hotel — 3-star hotel in Kastoria. Guest rating: 10/10 — Exceptional.
  5. Esperos Palace Luxury & Spa Hotel — 4-star hotel in Kastoria. Guest rating: 9.0/10 — Wonderful.

Where to stay in Mesopotamia?

To Spiti tis Sofias

To Spiti tis Sofias
Kastoria
$66
$77 total
includes taxes & fees
Aug 23 - Aug 24
To Spiti tis Sofias

Limneon Resort & Spa

Limneon Resort & Spa
Kastoria
$107
$139 total
includes taxes & fees
Sep 1 - Sep 2
Limneon Resort & Spa

Hotel Anastassiou

Hotel Anastassiou
Kastoria
$51
$61 total
includes taxes & fees
Aug 10 - Aug 11
Hotel Anastassiou

Chloe Hotel

Chloe Hotel
Kastoria
$102
$121 total
includes taxes & fees
Aug 16 - Aug 17
Chloe Hotel

Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel
Kastoria
$106
$132 total
includes taxes & fees
Aug 10 - Aug 11
Esperos Palace Luxury & Spa Hotel

Kyknos De Luxe Hotel

Kyknos De Luxe Hotel
Kastoria
$87
$101 total
includes taxes & fees
Aug 26 - Aug 27
Kyknos De Luxe Hotel

Orologopoulos Mansion

Orologopoulos Mansion
Kastoria
$124
$158 total
includes taxes & fees
Aug 11 - Aug 12
Orologopoulos Mansion

Guesthouse Vissinokipos

Guesthouse Vissinokipos
Kastoria
$73
$86 total
includes taxes & fees
Aug 10 - Aug 11
Guesthouse Vissinokipos

Anesis Hotel

Anesis Hotel
Kastoria
$56
$66 total
includes taxes & fees
Aug 10 - Aug 11
Anesis Hotel

Calma Hotel & Spa

Calma Hotel & Spa
Kastoria
$101
$127 total
includes taxes & fees
Aug 24 - Aug 25
Calma Hotel & Spa

The Sunset Haven Kastoria Modern Lake Elegance

The Sunset Haven Kastoria Modern Lake Elegance
Kastoria
$55
$215 total
includes taxes & fees
Aug 10 - Aug 11
The Sunset Haven Kastoria Modern Lake Elegance

Andromeda Boutique hotel

Andromeda Boutique hotel
Kastoria
$68
$100 total
includes taxes & fees
Aug 19 - Aug 20
Andromeda Boutique hotel

Le Marron

Le Marron
Voio
$129
$159 total
includes taxes & fees
Sep 1 - Sep 2
Le Marron

OIKOI - Luxury Suites & Maisonettes

OIKOI - Luxury Suites & Maisonettes
Kastoria
$101
$140 total
includes taxes & fees
Aug 10 - Aug 11
OIKOI - Luxury Suites & Maisonettes

Guest House Ilektra

Guest House Ilektra
Voio
$61
$72 total
includes taxes & fees
Aug 20 - Aug 21
Guest House Ilektra

Lūma Retreat

Lūma Retreat
Kastoria
$87
$101 total
includes taxes & fees
Aug 11 - Aug 12
Lūma Retreat

Guesthouse Monopati

Guesthouse Monopati
Amyntaio
$74
$86 total
includes taxes & fees
Aug 10 - Aug 11
Guesthouse Monopati

Arhontiko Christodoulou

Arhontiko Christodoulou
Prespes
$73
$86 total
includes taxes & fees
Aug 10 - Aug 11
Arhontiko Christodoulou

Anastasia s Kastoria Cozy Modern Garden Retreat

Anastasia s Kastoria Cozy Modern Garden Retreat
Kastoria
$125
$197 total
includes taxes & fees
Aug 11 - Aug 12
Anastasia s Kastoria Cozy Modern Garden Retreat
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Check out reviews of Mesopotamia hotels guests love

Calma Hotel & Spa

Calma Hotel & Spa

10/10 Excellent
"If you’re looking for a hotel, that is clean, spacious, warm and inviting this is the place for you. It has the perfect location to be out of the way but close enough to all of Kastoria and surrounding villages. Staff were kind and exceptional. Everyone was extremely helpful, courteous and made us feel like we were home. Rooms are spacious, constantly clean and replenished with towels daily. We had a simple corner suite that didn’t overlook much in a view but it was quiet all day long which was refreshing. Pool was beautifully maintained as well as the entire property. Pool did get very busy with locals due to the extreme heat, but with a morning reservation at the pool you had no problem having a spot even if you came back late in the afternoon. Breakfast was delicious with its standard staples but with new items as well. We cannot be more happy with our stay and we hope that you will consider booking this location as we know you will not be disappointed."
Patricia 10-night trip
Posted 3 days ago
Calma Hotel & Spa
Orologopoulos Mansion

Orologopoulos Mansion

10/10 Excellent
"This is the hotel we return to time and time again, and the one we are never disappointed by. * Clean: Perfectly clean. Daily refresh of linens and tidying of room. Public spaces pristine. Black out shades were a pleasant surprise in an antique building like this one. Loved that touch! * Customer service. Top-tier service. Warm and friendly but also give space. * Breakfast. Delicious pites, pastries, yogurt. Choice of barista-quality coffees. Lovely space to eat, both inside and outside in their private garden. * Location. One block from the lake (GREAT for jogging) and across the street from the plateia (square), with its choice of chic restaurants. Quiet when you need it to be. * Parking. Right in front every day, with no issue whatsoever. Always a perfect stay. Love this hotel!"
Paula 3-night trip
Posted 1 month ago
Orologopoulos Mansion
Guest House Ilektra

Guest House Ilektra

10/10 Excellent
"Friendly and courteous hosts, great food and excellent service "
Pantelia 1-night trip
Posted 8 months ago
Guest House Ilektra
Kyknos De Luxe Hotel

Kyknos De Luxe Hotel

10/10 Excellent
"The staff was warm and welcoming. The rooms were amazing and the breakfast was fantastic. Lots of ethnic Greek foods"
Theodora 4-night trip
Posted 10 months ago
Kyknos De Luxe Hotel
Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel

10/10 Excellent
"The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. "
Michal 3-night trip
Posted 1 year ago
Esperos Palace Luxury & Spa Hotel

Frequently asked questions

What hotels do travelers like in Mesopotamia?
Can I book a refundable hotel in Mesopotamia?
If you want the flexibility to change your travel plans to Mesopotamia, most hotels offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Mesopotamia be like during my trip?
The warmest months in Mesopotamia are usually August and July with an average temp of 69°F. January and February are the chilliest months when the average temp is 37°F. The rainiest months are November and December.
Why should I book my Mesopotamia hotel with Hotels.com?
There are plenty of reasons to book your Mesopotamia travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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