A vineyard with rows of grapevines, terraced fields, and mountains in the background.

Hotels in Santa Cruz

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Tonight

Oct 18 - Oct 19

Tomorrow

Oct 19 - Oct 20

Next weekend

Oct 23 - Oct 25

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Where to stay in Santa Cruz?

A pool area with a thatched-roof structure, palm trees, and a staircase leading to an upper level.

A conference room at Hotel Santa Cruz with rows of chairs, a carpeted floor, wooden beams, and chandeliers.

A hotel room with a bed, a sofa, a wooden coffee table, a lamp, and a picture on the wall.

A spa area with a hot tub, candles, and towels on a wooden table.

1. Santa Cruz Plaza

Santa Cruz

$119

$119 total

Nov 8 - Nov 9

A bedroom with a large window, a bed, a wooden floor, and a wall-mounted artwork.

A water feature with rocks and a wooden deck.

A modern library with a geometric bookshelf design, a comfortable seating area, and a clear view of the outdoors.

A wall covered in colorful graffiti and tags, with a wine bottle on a wooden counter.

2. Vik Chile

San Vicente

$734

$734 total

Oct 21 - Oct 22

A pool area with two people sitting by the pool, surrounded by wooden barrels and a chair under a white umbrella.

A rustic wooden structure with a door, surrounded by greenery.

A bar with a wooden counter, bar stools, and a wine rack with bottles.

A spacious living room with a wooden staircase, a dining area with a table and chairs, and a kitchen area with a refrigerator and cabinets.

3. Hotel Cava Colchagua

Santa Cruz

$143

$143 total

Oct 20 - Oct 21

A nighttime view of a hotel with multiple illuminated rooms and a swimming pool reflecting the lights.

A wooden deck with a view of a forest and mountains.

A spacious living room with two sofas facing a large window overlooking a garden.

A multi-story hotel with balconies, large windows, and a swimming pool in the foreground.

4. La Perla Hotel

Santa Cruz

$77

$77 total

Oct 19 - Oct 20

A pool area with a table and chairs, surrounded by a tiled deck and a covered patio.

A building with a paved entrance and stone walls, illuminated by warm lights.

A room with a large glass door leading to an outdoor area, a small table with a lamp, and a decorative plant.

A spacious room with a grand piano, a comfortable armchair, and a dining table with a vase of flowers.

5. Hotel Boutique Grand Cru

Santa Cruz

$91

$91 total

Oct 19 - Oct 20

A wooden building with large windows and a covered patio area with chairs and a table.

A pool area with white metal chairs and tables, surrounded by potted plants and umbrellas.

A hotel with a stone facade, wooden balconies, and a sign that reads "HOTEL VENDIMIO".

A cozy room with a wooden staircase, a round table with candles, and a comfortable sofa.

6. Hotel Boutique Vendimia Premium

Santa Cruz

$62

$62 total

Oct 19 - Oct 20

A large estate with multiple buildings, a swimming pool, and extensive vineyard fields.

A woman walking through a vineyard path with a building in the background.

A large swimming pool with a building featuring a tiled roof and columns in the background.

A covered balcony with a view of a swimming pool and vineyard.

7. TerraViña

Santa Cruz

$180

$180 total

Oct 19 - Oct 20

A traditional building with a tiled roof, a welcoming sign, and a large glass door.

A rustic dining area with wooden tables and chairs, large windows, and potted plants.

A traditional house with a tiled roof, a garden with a large pot and a wheelbarrow, and a well-maintained lawn.

A cozy bedroom with a large bed, two chairs, a small table, and a chandelier.

8. Hotel Vendimia Parador

Santa Cruz

$49

$49 total

Nov 11 - Nov 12

A modern outdoor pool area with lounge chairs, a covered patio, and a brick pool.

A dining area with wooden tables, chairs, and a variety of food items. There are ceiling fans and a chandelier.

A modern building with a tiled roof and large windows, surrounded by a grassy field and trees.

A bedroom with a bed, pillows, a patterned blanket, and three wall-mounted decorative plates.

9. Noi Blend Colchagua

Palmilla

$167

$167 total

Oct 19 - Oct 20

A swimming pool with lounge chairs and umbrellas, surrounded by trees.

A wooden deck with outdoor seating, a small table, and a blue door labeled "SALA MASAJES".

A garden pathway leading to a building with a reception sign.

A dining area with multiple tables set for breakfast, featuring white tablecloths, wooden chairs, and various breakfast items.

10. Casa Calfu

Santa Cruz

$82

$82 total

Oct 19 - Oct 20

A restaurant with multiple tables set for dining, featuring a wine rack and large windows.

A modern bar area with seating, including a leather sofa and two green armchairs, and a wooden coffee table with decorative items.

A long table set for dining with chairs, under large yellow canopies, against a wooden wall.

A modern gym with treadmills, an elliptical, and a stationary bike.

11. Hotel Curicó

Curicó

$72

$72 total

Oct 31 - Nov 1

A bathroom with a white sink, toilet, and shower curtain.

A dining area with a wooden table and chairs, a ceiling fan, a mounted TV, and a wall-mounted wine rack.

A reception area with a wooden reception desk, a computer, and a fire extinguisher. There is a door with a window and a wall-mounted emergency exit sign.

A bedroom with a bed, a bedside table with a lamp, a window with curtains, and a door.

12. Tierra y Vino

Santa Cruz

An outdoor dining area with wooden tables and chairs, surrounded by lush greenery and a glass door leading to a garden.

A garden with a white umbrella, a red chair, and various plants.

A cozy interior with a sofa, a round table, and a large window.

A garden pathway leading to a covered structure with a glass door.

13. Hostal Vida 2000

Santa Cruz

$32

$32 total

Oct 19 - Oct 20

A large building with a tiled roof, surrounded by lush greenery and flowering plants.

A hotel room with a wooden table, two bedside tables, a sofa, and a bed.

A person sitting by a pool with a drink, a glass of water, and a snack tray.

A cozy living room with a fireplace, wooden furniture, and a chandelier.

14. Hotel Viña La Playa

Peralillo

$214

$214 total

Nov 1 - Nov 2

The exterior of Hotel Diego de Almagro with a prominent entrance, large columns, and a modern facade.

A hotel room with a large bed, a desk, a chair, a TV, and a wardrobe.

A spacious lobby with a polished tile floor, a reception desk, several seating areas, and a large window providing natural light.

A restaurant with a central counter, multiple tables with chairs, and a bar area.

15. Hotel Diego de Almagro Curico

Curicó

A modern, well-lit building with a glass facade, a wooden deck with lounge chairs, and a hanging light fixture.

A modern bedroom with a bed, bedside table, and a glass table with two wine glasses and a bottle.

A vineyard path with rows of grapevines and a building in the background.

A modern bathroom with a wooden vanity, a large mirror, and a hanging light fixture.

16. Vibo Wine Lodge

Santa Cruz

A wooden building with outdoor seating and a covered patio area.

A yellow building with a tiled roof and a covered porch.

A hotel with a covered outdoor area and a yellow facade.

An outdoor seating area with wicker furniture and a lantern.

17. Hotel Ontiveros

San Fernando

$64

$64 total

Oct 23 - Oct 24

A person relaxing by a poolside chair reading a book.

A traditional building with a tiled roof, a covered entrance, and potted plants.

A covered outdoor area with a brick pathway, wooden columns, and greenery.

A wooden wine rack with bottles, a wine bottle in a bucket, and a glass of red wine on a table.

18. Hacienda Histórica Marchigüe

Marchihue

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A wooden building with large windows and a covered patio area with chairs and a table.

A pool area with white metal chairs and tables, surrounded by potted plants and umbrellas.

A hotel with a stone facade, wooden balconies, and a sign that reads "HOTEL VENDIMIO".

A cozy room with a wooden staircase, a round table with candles, and a comfortable sofa.

Hotel Boutique Vendimia Premium

Santa Cruz

$79

per night

$158 total

A traditional building with a tiled roof, a welcoming sign, and a large glass door.

A rustic dining area with wooden tables and chairs, large windows, and potted plants.

A traditional house with a tiled roof, a garden with a large pot and a wheelbarrow, and a well-maintained lawn.

A cozy bedroom with a large bed, two chairs, a small table, and a chandelier.

Hotel Vendimia Parador

Santa Cruz

$76

per night

$151 total

A pool area with two people sitting by the pool, surrounded by wooden barrels and a chair under a white umbrella.

A rustic wooden structure with a door, surrounded by greenery.

A bar with a wooden counter, bar stools, and a wine rack with bottles.

A spacious living room with a wooden staircase, a dining area with a table and chairs, and a kitchen area with a refrigerator and cabinets.

Hotel Cava Colchagua

Santa Cruz

$110 off

$192

per night

$385 total

A nighttime view of a hotel with multiple illuminated rooms and a swimming pool reflecting the lights.

A wooden deck with a view of a forest and mountains.

A spacious living room with two sofas facing a large window overlooking a garden.

A multi-story hotel with balconies, large windows, and a swimming pool in the foreground.

La Perla Hotel

Santa Cruz

$17 off

$77

per night

$154 total

A swimming pool with lounge chairs and umbrellas, surrounded by trees.

A wooden deck with outdoor seating, a small table, and a blue door labeled "SALA MASAJES".

A garden pathway leading to a building with a reception sign.

A dining area with multiple tables set for breakfast, featuring white tablecloths, wooden chairs, and various breakfast items.

Casa Calfu

Santa Cruz

$20 off

$90

per night

$180 total

A pool area with a table and chairs, surrounded by a tiled deck and a covered patio.

A building with a paved entrance and stone walls, illuminated by warm lights.

A room with a large glass door leading to an outdoor area, a small table with a lamp, and a decorative plant.

A spacious room with a grand piano, a comfortable armchair, and a dining table with a vase of flowers.

Hotel Boutique Grand Cru

Santa Cruz

$29 off

$131

per night

$262 total

A cozy room with a bed, a table, and a view of the outdoors through a triangular window.

An outdoor seating area with wooden benches and tables, surrounded by trees.

A wooden shelf with towels hanging on hooks, labeled "Colchagui Tiny Lodge."

A rustic cabin with a wooden deck, surrounded by lush greenery and a mountainous backdrop.

Colchagua Tiny Lodge

Santa Cruz

$41 off

$183

per night

$365 total

A wooden building with large windows and a covered patio area with chairs and a table.

A pool area with white metal chairs and tables, surrounded by potted plants and umbrellas.

A hotel with a stone facade, wooden balconies, and a sign that reads "HOTEL VENDIMIO".

A cozy room with a wooden staircase, a round table with candles, and a comfortable sofa.

Hotel Boutique Vendimia Premium

Santa Cruz

$62

per night

$62 total

A traditional building with a tiled roof, a welcoming sign, and a large glass door.

A rustic dining area with wooden tables and chairs, large windows, and potted plants.

A traditional house with a tiled roof, a garden with a large pot and a wheelbarrow, and a well-maintained lawn.

A cozy bedroom with a large bed, two chairs, a small table, and a chandelier.

Hotel Vendimia Parador

Santa Cruz

$49

per night

$49 total

A pool area with a thatched-roof structure, palm trees, and a staircase leading to an upper level.

A conference room at Hotel Santa Cruz with rows of chairs, a carpeted floor, wooden beams, and chandeliers.

A hotel room with a bed, a sofa, a wooden coffee table, a lamp, and a picture on the wall.

A spa area with a hot tub, candles, and towels on a wooden table.

Santa Cruz Plaza

Santa Cruz

$126

per night

$126 total

A pool area with two people sitting by the pool, surrounded by wooden barrels and a chair under a white umbrella.

A rustic wooden structure with a door, surrounded by greenery.

A bar with a wooden counter, bar stools, and a wine rack with bottles.

A spacious living room with a wooden staircase, a dining area with a table and chairs, and a kitchen area with a refrigerator and cabinets.

Hotel Cava Colchagua

Santa Cruz

$19 off

$167

per night

$167 total

A nighttime view of a hotel with multiple illuminated rooms and a swimming pool reflecting the lights.

A wooden deck with a view of a forest and mountains.

A spacious living room with two sofas facing a large window overlooking a garden.

A multi-story hotel with balconies, large windows, and a swimming pool in the foreground.

La Perla Hotel

Santa Cruz

$9 off

$77

per night

$77 total

A swimming pool with lounge chairs and umbrellas, surrounded by trees.

A wooden deck with outdoor seating, a small table, and a blue door labeled "SALA MASAJES".

A garden pathway leading to a building with a reception sign.

A dining area with multiple tables set for breakfast, featuring white tablecloths, wooden chairs, and various breakfast items.

Casa Calfu

Santa Cruz

$9 off

$82

per night

$82 total

A cozy room with a bed, a table, and a view of the outdoors through a triangular window.

An outdoor seating area with wooden benches and tables, surrounded by trees.

A wooden shelf with towels hanging on hooks, labeled "Colchagui Tiny Lodge."

A rustic cabin with a wooden deck, surrounded by lush greenery and a mountainous backdrop.

Colchagua Tiny Lodge

Santa Cruz

$20 off

$183

per night

$183 total

You can also stay at hotels with a pool in Santa Cruz

A pool area with a thatched-roof structure, palm trees, and a staircase leading to an upper level.

A conference room at Hotel Santa Cruz with rows of chairs, a carpeted floor, wooden beams, and chandeliers.

A hotel room with a bed, a sofa, a wooden coffee table, a lamp, and a picture on the wall.

A spa area with a hot tub, candles, and towels on a wooden table.

Santa Cruz Plaza

Santa Cruz

$119

$119 total

Nov 8 - Nov 9

A wooden building with large windows and a covered patio area with chairs and a table.

A pool area with white metal chairs and tables, surrounded by potted plants and umbrellas.

A hotel with a stone facade, wooden balconies, and a sign that reads "HOTEL VENDIMIO".

A cozy room with a wooden staircase, a round table with candles, and a comfortable sofa.

Hotel Boutique Vendimia Premium

Santa Cruz

$62

$62 total

Oct 19 - Oct 20

A large estate with multiple buildings, a swimming pool, and extensive vineyard fields.

A woman walking through a vineyard path with a building in the background.

A large swimming pool with a building featuring a tiled roof and columns in the background.

A covered balcony with a view of a swimming pool and vineyard.

TerraViña

Santa Cruz

$180

$180 total

Oct 19 - Oct 20

A pool area with two people sitting by the pool, surrounded by wooden barrels and a chair under a white umbrella.

A rustic wooden structure with a door, surrounded by greenery.

A bar with a wooden counter, bar stools, and a wine rack with bottles.

A spacious living room with a wooden staircase, a dining area with a table and chairs, and a kitchen area with a refrigerator and cabinets.

Hotel Cava Colchagua

Santa Cruz

$143

$143 total

Oct 20 - Oct 21

A pool area with a table and chairs, surrounded by a tiled deck and a covered patio.

A building with a paved entrance and stone walls, illuminated by warm lights.

A room with a large glass door leading to an outdoor area, a small table with a lamp, and a decorative plant.

A spacious room with a grand piano, a comfortable armchair, and a dining table with a vase of flowers.

Hotel Boutique Grand Cru

Santa Cruz

$91

$91 total

Oct 19 - Oct 20

A nighttime view of a hotel with multiple illuminated rooms and a swimming pool reflecting the lights.

A wooden deck with a view of a forest and mountains.

A spacious living room with two sofas facing a large window overlooking a garden.

A multi-story hotel with balconies, large windows, and a swimming pool in the foreground.

La Perla Hotel

Santa Cruz

$77

$77 total

Oct 19 - Oct 20

A traditional building with a tiled roof, a welcoming sign, and a large glass door.

A rustic dining area with wooden tables and chairs, large windows, and potted plants.

A traditional house with a tiled roof, a garden with a large pot and a wheelbarrow, and a well-maintained lawn.

A cozy bedroom with a large bed, two chairs, a small table, and a chandelier.

Hotel Vendimia Parador

Santa Cruz

$49

$49 total

Nov 11 - Nov 12

A swimming pool with lounge chairs and umbrellas, surrounded by trees.

A wooden deck with outdoor seating, a small table, and a blue door labeled "SALA MASAJES".

A garden pathway leading to a building with a reception sign.

A dining area with multiple tables set for breakfast, featuring white tablecloths, wooden chairs, and various breakfast items.

Casa Calfu

Santa Cruz

$82

$82 total

Oct 19 - Oct 20

View all properties

Go beyond your typical stay in Santa Cruz

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Our prices for hotels in Santa Cruz are cheapest in April

Top landmarks in Santa Cruz

Lapostolle Clos Apalta Winery

9.4/10 (21 reviews)

Travelers might want a tour of Lapostolle Clos Apalta Winery, just one of the places to visit, and located 5.3 mi (8.5 km) from central Santa Cruz.

Casino Colchagua

8.0/10 (6 reviews)

Casino Colchagua is 1.4 mi (2.2 km) from central Santa Cruz, why not stop by during your stay.

Laura Hartwig Winery

9.0/10 (17 reviews)

Travelers might want a tour of Laura Hartwig Winery, just one of the places to visit, and located 0.8 mi (1.3 km) from central Santa Cruz.

Colchagua Campo y Vino

9.4/10 (3 reviews)

Colchagua Campo y Vino is 1.4 mi (2.2 km) from central Santa Cruz, why not stop by during your stay.

Bodega Viña Viu Manent

10.0/10 (1 review)

Travelers might want a tour of Bodega Viña Viu Manent, just one of the places to visit, and located 3.4 mi (5.4 km) from central Santa Cruz.

Museo de Colchagua

9.6/10 (24 reviews)

The center of Santa Cruz is home to cultural attractions like Museo de Colchagua, so you might want to stop by during your stay. If you want to experience more of the culture Santa Cruz has to offer, head to Casino Colchagua, Laura Hartwig Winery, and Colchagua Campo y Vino.

Plaza de Armas

8.2/10 (34 reviews)

If you're planning a bit of sightseeing during your trip, head to Plaza de Armas— just one of the monuments in central Santa Cruz.

Learn more about Santa Cruz

Notable for its wineries, Santa Cruz features attractions such as Casino Colchagua and Colchagua Campo y Vino. This relaxing city has something for everyone including restaurants as well as sights like Lapostolle Clos Apalta Winery and Millahue Valley. All are within a rural setting.

See all hotels in Santa Cruz

A vineyard with rows of grapevines, terraced fields, and mountains in the background.

Check out reviews of Santa Cruz hotels guests love

A swimming pool with lounge chairs and umbrellas, surrounded by trees.

A wooden deck with outdoor seating, a small table, and a blue door labeled "SALA MASAJES".

A garden pathway leading to a building with a reception sign.

A dining area with multiple tables set for breakfast, featuring white tablecloths, wooden chairs, and various breakfast items.

Casa Calfu

Santa Cruz

10/10 Exceptional

United States

Terrence

A traditional building with a tiled roof, a welcoming sign, and a large glass door.

A rustic dining area with wooden tables and chairs, large windows, and potted plants.

A traditional house with a tiled roof, a garden with a large pot and a wheelbarrow, and a well-maintained lawn.

A cozy bedroom with a large bed, two chairs, a small table, and a chandelier.

Hotel Vendimia Parador

Santa Cruz

10/10 Exceptional

United States

Kris

A large estate with multiple buildings, a swimming pool, and extensive vineyard fields.

A woman walking through a vineyard path with a building in the background.

A large swimming pool with a building featuring a tiled roof and columns in the background.

A covered balcony with a view of a swimming pool and vineyard.

TerraViña

Santa Cruz

10/10 Exceptional

Terra Vina is a nice hotel, just outside of town. It’s surrounded by vineyards, and is convenient to everything. The front desk staff is very helpful, and are “English Friendly “. They will make reservations for you, give helpful advice, and are all around a joy to interact with. The breakfast has fresh fruits, fresh breads, eggs, cereals, etc. We didn’t eat any other meals there. Rooms are spacious and comfortable. We ate at Vino Bello, restaurant next door, and it was good and reasonably...

United States

Laurie

A nighttime view of a hotel with multiple illuminated rooms and a swimming pool reflecting the lights.

A wooden deck with a view of a forest and mountains.

A spacious living room with two sofas facing a large window overlooking a garden.

A multi-story hotel with balconies, large windows, and a swimming pool in the foreground.

La Perla Hotel

Santa Cruz

10/10 Exceptional

United States

tim

A pool area with two people sitting by the pool, surrounded by wooden barrels and a chair under a white umbrella.

A rustic wooden structure with a door, surrounded by greenery.

A bar with a wooden counter, bar stools, and a wine rack with bottles.

A spacious living room with a wooden staircase, a dining area with a table and chairs, and a kitchen area with a refrigerator and cabinets.

Hotel Cava Colchagua

Santa Cruz

10/10 Exceptional

United States

Arturo

A wooden building with outdoor seating and a covered patio area.

A yellow building with a tiled roof and a covered porch.

A hotel with a covered outdoor area and a yellow facade.

An outdoor seating area with wicker furniture and a lantern.

Hotel Ontiveros

San Fernando

10/10 Exceptional

United States

Tomas

A modern outdoor pool area with lounge chairs, a covered patio, and a brick pool.

A dining area with wooden tables, chairs, and a variety of food items. There are ceiling fans and a chandelier.

A modern building with a tiled roof and large windows, surrounded by a grassy field and trees.

A bedroom with a bed, pillows, a patterned blanket, and three wall-mounted decorative plates.

Noi Blend Colchagua

Palmilla

10/10 Exceptional

United States

Barbara

Frequently Asked Questions

What accommodations do travelers recommend in Santa Cruz?

Guests like Santa Cruz Plaza, Hotel Cava Colchagua and La Perla Hotel.

Where can I find free parking at my hotel in Santa Cruz?

These hotels offer the perk of free parking: Tierra y Vino, Hostal Gomero and Whay Hau.

Can I book refundable accommodations in Santa Cruz?

If you need the flexibility to change your plans to Santa Cruz, most properties offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Santa Cruz be like during my visit?

January and February are typically the warmest months in Santa Cruz when the average temp is 70°F. July and August are the coldest months when the average temperature is 50°F. June and August are the months with the most rain.

Why should I book my Santa Cruz hotel through Hotels.com?

There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.