Hotels in Santa Cruz

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Apr 19 - Apr 20
Tomorrow
Apr 20 - Apr 21
Next weekend
Apr 24 - Apr 26
In two weeks
May 1 - May 3

Where to stay in Santa Cruz?

Interior detail
Hotel Boutique Grand Cru
Hotel Boutique Grand Cru
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (14 reviews)
Relax at this boutique hotel in Chile's wine country near Museo de Colchagua. Enjoy a refreshing swim in the outdoor pool or unwind in the steam room. Free perks include breakfast, WiFi, and parking for exploring nearby attractions.
The price is $144
$144 total
Apr 20 - Apr 21
Hotel Boutique Grand Cru
1 bedroom, laptop workspace, soundproofing, free WiFi
Colchagua Tiny Lodge
Colchagua Tiny Lodge
3.5 star property
Santa Cruz
9.8 out of 10, Exceptional, (8 reviews)
Unwind in this cozy Santa Cruz lodge with private hot tubs in each cabin. Kitchenettes and a garden terrace add charm while you explore nearby Lapostolle Clos Apalta and Viña Viu Manent wineries. Enjoy free WiFi and parking during your Chilean wine country escape.
The price is $211
$211 total
Apr 27 - Apr 28
Colchagua Tiny Lodge
Outdoor pool, pool umbrellas, sun loungers
Hotel Boutique Solaz Bella Vista de Colchagua
Hotel Boutique Solaz Bella Vista de Colchagua
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (98 reviews)
Soak in the Chilean sunshine at this Santa Cruz retreat with an outdoor pool and rejuvenating spa treatments. Just minutes from local wineries and Plaza de Armas, the hotel offers free breakfast, WiFi, and parking plus a garden terrace and welcoming bar.
The price is $76
$76 total
Apr 20 - Apr 21
Hotel Boutique Solaz Bella Vista de Colchagua
Seasonal outdoor pool, sun loungers
La Perla Hotel
La Perla Hotel
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (111 reviews)
This business-friendly hotel offers complimentary breakfast, WiFi, and parking near Museo de Colchagua. Unwind with massages or manicures, sip drinks at the bar, or relax while children enjoy their own pool.
The price is $80
$80 total
Apr 21 - Apr 22
La Perla Hotel
Front of property
Hotel Vendimia Parador
Hotel Vendimia Parador
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (85 reviews)
Escape to Hotel Vendimia Parador in Santa Cruz, where an indoor and outdoor pool with swim-up bar await. Close to Laura Hartwig Winery and Plaza de Armas, this colonial retreat offers free WiFi, parking, and grocery service, with staff that guests consistently praise.
The price is $89
$89 total
May 13 - May 14
Hotel Vendimia Parador
Aerial view
TerraViña
TerraViña
3.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (213 reviews)
Immerse yourself in wine country at this Santa Cruz retreat, complete with its own winery, refreshing outdoor pool, and restaurant. After vineyard exploration, enjoy drinks at the bar or relax in the garden terrace near Laura Hartwig Winery.
The price is $135
$135 total
May 17 - May 18
TerraViña
Couples treatment rooms, hot springs, massages
Hotel Cava Colchagua
Hotel Cava Colchagua
4.0 star property
Santa Cruz
8.8 out of 10, Excellent, (174 reviews)
This Santa Cruz spa hotel offers an attached winery and outdoor pool near Laura Hartwig Winery. After exploring Colchagua Campo y Vino, guests enjoy complimentary breakfast, massage treatments, and drinks at the bar. The train station proximity ensures easy regional access.
The price is $163
$163 total
Apr 20 - Apr 21
Hotel Cava Colchagua
Outdoor pool, sun loungers
Santa Cruz Plaza
Santa Cruz Plaza
4.0 star property
Santa Cruz
8.8 out of 10, Excellent, (356 reviews)
Unwind at this tranquil hotel near Plaza de Armas featuring a full-service spa with massages and hydrotherapy. Enjoy the rooftop terrace, outdoor pool, and free kids' club while the 24-hour fitness center keeps your routine intact. Museo de Colchagua is just moments away.
The price is $157
$157 total
Apr 26 - Apr 27
Santa Cruz Plaza
Courtyard
Hotel Boutique Vendimia Premium
Hotel Boutique Vendimia Premium
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (139 reviews)
This colonial hotel in the entertainment district offers a seasonal outdoor pool, children's pool, and tranquil garden terrace. Near Museo de Colchagua and Plaza de Armas, you'll appreciate free WiFi and parking while enjoying the boutique atmosphere.
The price is $92
$92 total
May 13 - May 14
Hotel Boutique Vendimia Premium
Exterior
Hotel Ontiveros
Hotel Ontiveros
3.5 star property
San Fernando
9.6 out of 10, Exceptional, (25 reviews)
Unwind in Hotel Ontiveros' tranquil garden or terrace after exploring nearby Iglesia de San Francisco and Plaza de San Fernando. Enjoy complimentary breakfast before venturing out, then return for refreshments at the restaurant and bar/lounge.
The price is $76
$76 total
Apr 20 - Apr 21
Hotel Ontiveros
Separate tub and shower, deep soaking tub, free toiletries, hair dryer
Vik Chile
Vik Chile
5.0 star property
San Vicente
9.2 out of 10, Wonderful, (184 reviews)
The price is $629
$629 total
May 6 - May 7
Vik Chile
Premium Twin | Free WiFi, bed sheets
Hotel Viña La Playa
Hotel Viña La Playa
3.5 star property
Peralillo
8.4 out of 10, Very Good, (18 reviews)
Immerse yourself in Chilean wine culture at this spa hotel featuring a winery, outdoor pool, and tennis court. Indulge in massages or body treatments before enjoying fusion cuisine at Tinguiririca restaurant. Near Hacienda El Huique with free breakfast, WiFi, and parking.
The price is $221
$221 total
Apr 21 - Apr 22
Hotel Viña La Playa
Seasonal outdoor pool, pool umbrellas, sun loungers
Noi Blend Colchagua
Noi Blend Colchagua
3.0 star property
Palmilla
9.0 out of 10, Wonderful, (148 reviews)
Set among Colchagua's vineyards, this hotel offers deep-tissue massages and regional cuisine at Ensamblaje Restaurant. After wine tasting at nearby MontGras Winery, unwind in the hot tub or sip drinks at the poolside bar while friendly staff attend to your needs.
The price is $153
$153 total
May 3 - May 4
Noi Blend Colchagua
Seasonal outdoor pool, open 10:00 AM to 8:00 PM, pool umbrellas
Hacienda Histórica Marchigüe
Hacienda Histórica Marchigüe
3.5 star property
Marchihue
8.0 out of 10, Very Good, (13 reviews)
Surrounded by Chile's wine region, this historic hacienda offers a seasonal outdoor pool and poolside bar for relaxation. After deep-tissue massages at the spa, enjoy dinner at the restaurant before exploring nearby Clos Santa Ana Winery.
The price is $198
$198 total
Apr 25 - Apr 26
Hacienda Histórica Marchigüe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Get last-minute hotel deals in Santa Cruz and save more

Sign in to unlock great savings.
Showing deals for:Apr 24 - Apr 26
Seasonal outdoor pool, sun loungers
La Perla Hotel

La Perla Hotel

La Perla Hotel
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (111 reviews)
$139 off
The price is $63
per night
$298 total
La Perla Hotel
Showing deals for:May 19 - May 20
Front of property
Hotel Vendimia Parador

Hotel Vendimia Parador

Hotel Vendimia Parador
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (85 reviews)
The price is $89
per night
$89 total
Hotel Vendimia Parador

When is the best time to visit Santa Cruz?

Our prices for hotels in Santa Cruz are cheapest in July
Price trends for hotels in Santa Cruz
Pricing is based on two traveler single night rates
View properties in April
Currently viewing crowd sizes and weather for April.
Typical weather for Santa Cruz
April
High 23°C / low 11°C. Sunny most days.
View properties in April
23°
weather_sun
April, no crowd data, average high temperature 23 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
19°
weather_sun
May, no crowd data, average high temperature 19 degrees Celsius, average low temperature 8 degrees Celsius. Sunny most days.
8°
15°
weather_sun
June, no crowd data, average high temperature 15 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
6°
14°
weather_sun
July, no crowd data, average high temperature 14 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
4°
16°
weather_sun
August, no crowd data, average high temperature 16 degrees Celsius, average low temperature 5 degrees Celsius. Sunny most days.
5°
18°
weather_sun
September, no crowd data, average high temperature 18 degrees Celsius, average low temperature 7 degrees Celsius. Sunny most days.
7°
21°
weather_sun
October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 8 degrees Celsius. Sunny most days.
8°
26°
weather_sun
November, no crowd data, average high temperature 26 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
29°
weather_sun
December, no crowd data, average high temperature 29 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
31°
weather_sun
January, no crowd data, average high temperature 31 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
30°
weather_sun
February, no crowd data, average high temperature 30 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
28°
weather_sun
March, no crowd data, average high temperature 28 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
Monthly weather averages (˚C)

Top landmarks in Santa Cruz

Lapostolle Clos Apalta Winery

4.7/5 (21 reviews)
Travelers might want a tour of Lapostolle Clos Apalta Winery, just one of the places to visit, and located 5.3 mi (8.5 km) from central Santa Cruz.
See properties

Colchagua Campo y Vino

4.7/5 (3 reviews)
Colchagua Campo y Vino is 1.4 mi (2.2 km) from central Santa Cruz, why not stop by during your stay.
See properties

Learn more about Santa Cruz

Notable for its wineries, Santa Cruz features attractions such as Colchagua Campo y Vino and Casino Colchagua. This relaxing city has something for everyone including restaurants as well as sights like Lapostolle Clos Apalta Winery and Millahue Valley. All are within a rural setting.

See all hotels in Santa Cruz
Rows of vineyards, Santa Cruz, Chile

Check out reviews of Santa Cruz hotels guests love

Hotel Vendimia Parador

Hotel Vendimia Parador

10/10 Excellent
" "I had a wonderful experience at this hotel. The location is fantastic—central and convenient to everything I wanted to see. The room was spotless and well-maintained, which I really appreciated. But what truly sets this place apart is the staff. From the front desk to the housekeeping team, everyone was genuinely warm, helpful, and went out of their way to be friendly. It made all the difference. I would absolutely stay here again." "
Yorba 1-night trip
Posted 3 weeks ago
Hotel Vendimia Parador

Frequently asked questions

What accommodations do travelers recommend in Santa Cruz?
Guests like Santa Cruz Plaza, Hotel Cava Colchagua and TerraViña.
Where can I find free parking at my hotel in Santa Cruz?
These hotels offer the perk of free parking: Tierra y Vino, Hostal Gomero and Whay Hau.
Can I book refundable accommodations in Santa Cruz?
If you need the flexibility to change your plans to Santa Cruz, most properties offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Cruz be like during my visit?
January and February are typically the warmest months in Santa Cruz when the average temp is 70°F. July and August are the coldest months when the average temperature is 50°F. June and August are the months with the most rain.
Why should I book my Santa Cruz hotel through Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.