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Hotels in Pythagorio

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Check prices for these dates

Tonight
Dec 22 - Dec 23
Tomorrow
Dec 23 - Dec 24
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Where to stay in Pythagorio?

Outdoor pool, pool umbrellas, sun loungers
Aegeon
Aegeon
3.0 star property
7.6 out of 10, Good, (19)
The price is $59
$66 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Aegeon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Budget hotels in Pythagorio and vicinity

Outdoor pool, pool umbrellas, sun loungers
Aegeon

Aegeon

Aegeon
3.0 star property
Samos
7.6 out of 10, Good, (19)
The price is $59
$66 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Aegeon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top landmarks in Pythagorio

Samos Pythagorion Archaeological Museum

If visiting museums in Pythagorio are on your list, you might want to check out the upcoming exhibitions at Samos Pythagorion Archaeological Museum, located in the heart of town. If you want to see more of the museums in Pythagorio, you can easily walk to Folklore Museum of the Nikolaos Dimitriou Foundation of Samos or Nikolaos Dimitriou Folklore Museum.
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Pythagoreion

4.3/5 (97 reviews)
If you're planning a bit of sightseeing during your trip, head to Pythagoreion— just one of the monuments in central Pythagorio.
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Learn more about Pythagorio

Notable for its seaside, Pythagorio features attractions such as Samos Pythagorion Archaeological Museum and Pythagoreion.

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Photo by Erdem Yücel
Open Photo by Erdem Yücel

Check out reviews of Pythagorio hotels guests love

Casa Cook Samos

Casa Cook Samos

10/10 Excellent
"Clean and modernly decorated rooms with all the facilities"
Aylin 3-night trip
Posted 2 months ago
Casa Cook Samos

Frequently asked questions

What accommodations do travelers recommend in Pythagorio?
Casa Cook Samos is an accommodation that is popular with guests.
Where can I find free parking at my hotel in Pythagorio?
Park your car for free at these properties: Astra Village, Potokaki Beachfront Hotel and Anna Studios. There are 5 choices you may want to check out on our site.
Can I book a refundable hotel in Pythagorio?
If you need the flexibility to change your travel plans to Pythagorio, most properties offer refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Pythagorio if I want an affordable accommodation?
Doryssa Lithos Hotel, Sunrise Hotel and Mykali are a few accommodations you might want to consider that'll save you money.
Where can I stay in Pythagorio if I want a vacation home instead of a traditional hotel?
Browse 5 vacation homes on our site. In addition, you can choose from 17 apartments.
What will the weather in Pythagorio be like during my trip?
August and July are typically the warmest months in Pythagorio when the average temp is 77°F. January and February are the coldest months when the average temperature is 55°F. January and December are the months with the most rain.
Why should I book my Pythagorio hotel with Hotels.com?
There are lots of reasons to book your Pythagorio trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.