Luxury Hotels in Pythagorio
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Tonight
Sep 8 - Sep 9Tomorrow
Sep 9 - Sep 10This weekend
Sep 11 - Sep 13Next weekend
Sep 18 - Sep 20Luxury Hotels in Pythagorio




Casa Cook Samos
Casa Cook SamosSamos
- On the beach
- Beachfront dining
- Full-service spa
- Concierge services
- Boutique feel
$208
$245 total
includes taxes & fees
Oct 1 - Oct 2




Doryssa Seaside Resort
Doryssa Seaside ResortSamos
- Direct access to the beach
- Beachfront dining
- Full-service spa
- Poolside bar
- Concierge services
$193
$229 total
includes taxes & fees
Sep 29 - Sep 30




Proteas Blu Resort - Adults Only
Proteas Blu Resort - Adults OnlySamos
- On private beach
- Ocean-view dining
- Full-service spa
- Poolside bar
- Concierge services
- Adults-only
$172
$206 total
includes taxes & fees
Oct 3 - Oct 4
$120
$143 total
includes taxes & fees
Sep 27 - Sep 28
$113
$135 total
includes taxes & fees
Oct 5 - Oct 6
$145
$171 total
includes taxes & fees
Sep 29 - Sep 30




Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)Samos
- 2 restaurants
- Full-service spa
- Outdoor pool
- Concierge services
$290
$335 total
includes taxes & fees
Oct 8 - Oct 9




Samian Mare Hotel Suites & Spa
Samian Mare Hotel Suites & SpaSamos
- Near private beach
- Full-service spa
- Poolside bar
- Concierge services
$114
$136 total
includes taxes & fees
Sep 13 - Sep 14




Erato by Samian Mare
Erato by Samian MareSamos
- Near private beach
- Ocean-view dining
- Full-service spa
- Poolside bar
- Concierge services
$142
$168 total
includes taxes & fees
Oct 2 - Oct 3
Top landmarks in Pythagorio
Samos Pythagorion Archaeological Museum
8.2/10 (12 reviews)
If visiting museums in Pythagorio are on your list, you might want to check out the upcoming exhibitions at Samos Pythagorion Archaeological Museum, located in the heart of town. If you want to see more of the museums in Pythagorio, you can easily walk to Folklore Museum of the Nikolaos Dimitriou Foundation of Samos or Nikolaos Dimitriou Folklore Museum.
Pythagoreion
8.8/10 (130 reviews)
If you're planning a bit of sightseeing during your trip, head to Pythagoreion— just one of the monuments in central Pythagorio.
Glicorisa Beach
8.0/10 (4 reviews)
If you can't wait to get to the beach, you might enjoy a trip to Glicorisa Beach located 1.3 mi (2 km) from central Pythagorio. Enjoy the sunset by the shore at Psili Amos Beach, Gagou Beach, and Potakaki beach.
Heraion of Samos
7.0/10 (16 reviews)
You might want to get your camera out and head to Heraion of Samos— just one of the landmarks located 3.2 mi (5.2 km) from central Pythagorio.
Tunnel of Eupalinos
If you're planning a bit of sightseeing during your trip, head to Tunnel of Eupalinos— just one of the landmarks located 0.6 mi (0.9 km) from central Pythagorio.
Folklore Museum of the Nikolaos Dimitriou Foundation of Samos
The center of Pythagorio is home to cultural attractions like Folklore Museum of the Nikolaos Dimitriou Foundation of Samos, so you might want to stop by during your stay. If you want to experience more of the culture Pythagorio has to offer, head to Pythagoreion, Samos Pythagorion Archaeological Museum, and Glicorisa Beach.
Monastery of Panagia Spiliani
Monastery of Panagia Spiliani is 0.4 mi (0.6 km) from central Pythagorio, why not stop by during your stay.
Potakaki beach
When the beach is calling your name, you might want to head down to Potakaki beach, located 0.7 mi (1.2 km) from central Pythagorio. Enjoy the sunset by the shore at Glicorisa Beach, İreo beach, and Kyriakoú.
















