Hotels in Santa Clara

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Villa Botero By Casa Mojito B&B
Villa Botero By Casa Mojito B&B
3.0 star property
Rio Hato
9.8 out of 10, Exceptional, (66 reviews)
  • cleanliness
    Wake up to paradise at Villa Botero, minutes from Rio Hato airport and nearby beaches.
The price is $122
$122 total
includes taxes & fees
Apr 2 - Apr 3
Villa Botero By Casa Mojito B&B
Grand Decameron Panama, A Trademark All Inclusive Resort
Grand Decameron Panama, A Trademark All Inclusive Resort
3.5 star property
Rio Hato
7.2 out of 10, Good, (1,002 reviews)
  • cleanliness
    Beachfront paradise with 6 pools, 9 restaurants, and a marina in Rio Hato.
The price is $225
$248 total
includes taxes & fees
Apr 19 - Apr 20
Grand Decameron Panama, A Trademark All Inclusive Resort
Gran Evenia Bijao & Convention Center
Gran Evenia Bijao & Convention Center
3.5 star property
Rio Hato
8.2 out of 10, Very Good, (1,005 reviews)
  • cleanliness
    Beachfront bliss with 3 outdoor pools and spa services at this all-inclusive Rio Hato retreat.
The price is $179
$197 total
includes taxes & fees
Apr 19 - Apr 20
Gran Evenia Bijao & Convention Center
Town Center Paradise in Playa Blanca
Town Center Paradise in Playa Blanca
2.5 star property
Rio Hato
7.8 out of 10, Good, (56 reviews)
  • cleanliness
    Escape to beach paradise with poolside relaxation minutes from Playa Blanca.
The price is $98
$108 total
includes taxes & fees
Apr 15 - Apr 16
Town Center Paradise in Playa Blanca
Playa Blanca Beach Resort - All Inclusive
Playa Blanca Beach Resort - All Inclusive
4.0 star property
Rio Hato
6.6 out of 10, (1,000 reviews)
  • cleanliness
    Ocean escape with free water park and private beach access just minutes from Playa Blanca.
The price is $163
$180 total
includes taxes & fees
Apr 29 - Apr 30
Playa Blanca Beach Resort - All Inclusive
Apartamento en Playa Blanca Town Center
Apartamento en Playa Blanca Town Center
3.0 star property
Rio Hato
7.8 out of 10, Good, (53 reviews)
  • cleanliness
    Seaside retreat with water park, pool, and multiple restaurants near Playa Blanca.
The price is $94
$103 total
includes taxes & fees
Apr 13 - Apr 14
Apartamento en Playa Blanca Town Center
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
5.0 star property
El Chiru
9.2 out of 10, Wonderful, (733 reviews)
  • cleanliness
    A beachfront paradise with 12 pools and a private stretch of golden sand in Panama.
The price is $222
$244 total
includes taxes & fees
Apr 9 - Apr 10
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
Casa Caracol Boutique Hotel
Casa Caracol Boutique Hotel
2.0 star property
Las Uvas
8.8 out of 10, Excellent, (22 reviews)
The price is $99
$109 total
includes taxes & fees
Apr 7 - Apr 8
Casa Caracol Boutique Hotel
B&B Casa Naturaleza Playa Corona
B&B Casa Naturaleza Playa Corona
3.0 star property
Las Uvas
2.0 out of 10, (1 review)
  • cleanliness
    Serene oceanside retreat near Playa Corona with outdoor pool and island vibes.
The price is $234
$257 total
includes taxes & fees
Apr 2 - Apr 3
B&B Casa Naturaleza Playa Corona
Hotel Las Catalinas Antón
Hotel Las Catalinas Antón
2.5 star property
Anton
8.4 out of 10, Very Good, (35 reviews)
  • cleanliness
    Feel refreshed at this Anton hotel with a lazy river and lively café on-site.
The price is $38
$42 total
includes taxes & fees
May 1 - May 2
Hotel Las Catalinas Antón
Hostal Las Catalinas Ecológicas
Hostal Las Catalinas Ecológicas
2.5 star property
El Valle de Anton
6.0 out of 10, (3 reviews)
  • cleanliness
    Scenic mountain eco-retreat with hiking and biking trails near El Valle attractions.
The price is $41
$45 total
includes taxes & fees
May 1 - May 2
Hostal Las Catalinas Ecológicas
Acuarela Hostal - Hostel
Acuarela Hostal - Hostel
2.0 star property
Rio Hato
8.6 out of 10, Excellent, (27 reviews)
  • cleanliness
    Experience seaside relaxation just steps from Farallón Beach at this welcoming hostel.
The price is $18
$42 total
includes taxes & fees
Apr 23 - Apr 24
Acuarela Hostal - Hostel
San Carlos Surf Resort & Eco Lodge
San Carlos Surf Resort & Eco Lodge
3.0 star property
Costa Esmeralda
6.4 out of 10, (5 reviews)
The price is $78
$102 total
includes taxes & fees
Apr 11 - Apr 12
San Carlos Surf Resort & Eco Lodge
Casa Blanca
Casa Blanca
4.0 star property
San Carlos
4.0 out of 10, (1 review)
  • cleanliness
    Scenic spa getaway in San Carlos with a full-service retreat and poolside relaxation.
The price is $73
$80 total
includes taxes & fees
Apr 2 - Apr 3
Casa Blanca
San Carlos Beach Inn
San Carlos Beach Inn
3.0 star property
San Carlos
8.6 out of 10, Excellent, (34 reviews)
  • cleanliness
    Oceanfront San Carlos hotel with rooftop terrace offers stunning beach views.
The price is $32
$35 total
includes taxes & fees
Apr 4 - Apr 5
San Carlos Beach Inn
Manglar Lodge
Manglar Lodge
3.0 star property
San Carlos
9.0 out of 10, Wonderful, (213 reviews)
  • cleanliness
    Peaceful beachfront escape steps from San Carlos Bay with international cuisine served daily.
The price is $60
$66 total
includes taxes & fees
Apr 6 - Apr 7
Manglar Lodge
Bay View Hotel
Bay View Hotel
3.0 star property
San Carlos
6.4 out of 10, (98 reviews)
The price is $70
$77 total
includes taxes & fees
Apr 2 - Apr 3
Bay View Hotel
Casa Madre Tierra
Casa Madre Tierra
3.0 star property
Los Llanitos
9.8 out of 10, Exceptional, (43 reviews)
  • cleanliness
    Experience breathtaking mountain views and eco-friendly comfort in Los Llanitos.
The price is $203
$223 total
includes taxes & fees
Apr 5 - Apr 6
Casa Madre Tierra
Caracoral Hotel Boutique & Spa
Caracoral Hotel Boutique & Spa
3.0 star property
El Valle de Anton
9.6 out of 10, Exceptional, (64 reviews)
  • cleanliness
    Escape to a mountainside spa retreat with deep-tissue massages and outdoor pool.
The price is $179
$197 total
includes taxes & fees
Apr 5 - Apr 6
Caracoral Hotel Boutique & Spa
Cabaña Villa Victoria
Cabaña Villa Victoria
2.5 star property
El Valle de Anton
9.6 out of 10, Exceptional, (60 reviews)
  • cleanliness
    Serene garden cottage retreat a short drive from El Valle's market and attractions.
The price is $70
$77 total
includes taxes & fees
Apr 10 - Apr 11
Cabaña Villa Victoria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Clara

The region around Santa Clara is home to attractions such as Playa Blanca and Santa Clara Beach.

Santa Clara, Panama

Check out reviews of Santa Clara hotels guests love

Frequently asked questions

What accommodations do travelers recommend in Santa Clara?
Villa Botero By Casa Mojito B&B is a property that our guests really like.
Can I book a refundable hotel in Santa Clara?
If you're looking for the flexibility to change your plans to Santa Clara, most accommodations provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Santa Clara if I want a vacation home instead of a traditional hotel?
If you're looking for a good alternative to a hotel, look over our selection of 6 vacation homes.
What will the weather in Santa Clara be like during my visit?
With an average temperature of 78°F, Santa Clara is a great place if you want to enjoy the sunshine year all year long.
Why should I book my Santa Clara hotel through Hotels.com?
There are plenty of reasons to book your Santa Clara travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.