If you're looking to discover somewhere new, look no further than Perryville. Whether you're planning to stay for a night or for the week, the area around Perryville has accommodations to fit every need. Search for hotels in Perryville with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Perryville hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Perryville hotel deals are here with our lowest price guarantee.
Hotels in Perryville
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Perryville?

Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHG
9.4 out of 10, Exceptional, (478)
The price is $94
$107 total
includes taxes & fees
Jul 13 - Jul 14
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Perryville
Pet friendly
Top landmarks in Perryville
National Shrine of Our Lady of the Miraculous Medal
Find out about the history of Perryville when you take a trip to National Shrine of Our Lady of the Miraculous Medal. Take in the festivals while you're in the area.
Perryville and related destinations
Explore the historic downtown, where Civil War-era buildings house quaint shops and local eateries. Visit the American Tractor Museum to marvel at vintage farm equipment or catch a show at the Perry Park Center.
Check out reviews of Perryville hotels guests love

Tru By Hilton Cape Girardeau
10/10 Excellent
Frequently asked questions
Find out more about Perryville
Find out more about Perryville
Keep exploring
Keep exploring
- Landmarks
- Amenities
- Hotels close to nearby airports
- Nearby cities
- Top cities in United States of America
- More Hotels
- Most popular destinations
- More ways to book
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Hotels near Perryville Country Club
- Hotels near Missouri's National Veterans Memorial
- Hotels near Cross Trails Medical Center
- Hotels near Sainte Genevieve Winery
- Hotels near Hawn State Park
- Hotels near Pickle Springs Natural Area
- Hotels near Crown Valley Winery
- Hotels near Little Grand Canyon Trail Trailhead
- Hotels near Popeye Museum
- Hotels near Hunter Valley Winery
- Hotels near Pomona Winery
- Las Vegas Hotels
- New York Hotels
- Orlando Hotels
- Myrtle Beach Hotels
- Chicago Hotels
- San Diego Hotels
- Panama City Beach Hotels
- Destin Hotels
- Los Angeles Hotels
- Ocean City Hotels
- Miami Hotels
- Boston Hotels
- Gulf Shores Hotels
- Nashville Hotels
- Atlantic City Hotels
- Pigeon Forge Hotels
- Atlanta Hotels
- San Francisco Hotels
- Houston Hotels
- Virginia Beach Hotels
Most popular destinations
Hotels
Cheap Hotels in San DiegoHotels in BransonHotels with Parking in Cape GirardeauHotels in BooneCheap Hotels in Twin FallsCheap Hotels in KirksvilleHotels in WestonHotels in Emerald IsleHotels with Free Breakfast in WarrentonHotels with Parking in IronwoodHotels in LinnHotels in Big SpringFamily Hotels in LebanonHotels in LaconiaCheap Hotels in BiloxiFamily Hotels in ColbyHotels in LawrencevilleHotels in NeenahHotels in McAllenCheap Hotels in HamptonHotels in PellaCheap Hotels in DothanHotels in AnaheimHotels in South Lake TahoeHotels in SikestonHotels with a Pool in CamdentonBusiness Hotels in HannibalHotels in Lake OzarkHotels in BolivarCheap Hotels in Branson