Hotels logo

Hotels in Chillicothe

October 2026
3
November 2026

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Next weekend
Oct 9 - Oct 11
In two weeks
Oct 16 - Oct 18

Where to stay in Chillicothe?

A hotel room with a large bathtub, a bed with a headboard, a desk, and a chair.
A spacious living room with a large window, a sofa, a chair, a coffee table, and a lamp.
A reception area with a black and white patterned counter, hanging pendant lights, and a wall-mounted artwork.
A modern kitchen with dark cabinets, a microwave, a juice dispenser, and a decorative wall piece.

1. Best Western Brookfield

Best Western Brookfield
Brookfield
$116
$126 total
includes taxes & fees
Oct 5 - Oct 6
Best Western Brookfield
A spacious living area with two armchairs, a wooden coffee table with a floral centerpiece, and a kitchen area with wooden cabinets and a television.
A bathroom with a white toilet, a sink with a mirror, and toiletries on the counter.
A gas station with a brick facade, large windows, and a covered entrance.
A swimming pool with a fountain, surrounded by lounge chairs and a brick wall.

2. Motel 6 – Chillicothe, MO

Motel 6 – Chillicothe, MO
Chillicothe
$71
$80 total
includes taxes & fees
Oct 4 - Oct 5
Motel 6 – Chillicothe, MO
A hotel bathroom with a large bathtub, a television, a desk, and a chair.
A reception area with a stone wall, a clock, and a Super 8 by Wyndham sign.
A gazebo with picnic tables and benches, surrounded by a grassy field and farm equipment in the background.
A hotel with a covered outdoor seating area, a flagpole with an American flag, and a parking lot with several cars.

3. Super 8 by Wyndham Chillicothe

Super 8 by Wyndham Chillicothe
Chillicothe
$79
$90 total
includes taxes & fees
Nov 1 - Nov 2
Super 8 by Wyndham Chillicothe
A modern hotel room with a spa area, including a bathtub, a flat-screen TV, and a seating area with ottomans.
A reception desk with a Westbridge logo, a laptop, and a patterned tile design.
A corner room with a jacuzzi, a stone-patterned wall, and a modern light fixture.
A modern kitchen with white cabinets, a refrigerator, a microwave, and a coffee machine. There are two pendant lights hanging above the counter.

4. Westbridge Inn & Suites Carrollton

Westbridge Inn & Suites Carrollton
Carrollton
$102
$118 total
includes taxes & fees
Oct 4 - Oct 5
Westbridge Inn & Suites Carrollton
A spacious kitchen with wooden cabinets, a dining area with a table and chairs, and a hallway leading to another room.
A multi-story hotel with a flat roof, a swimming pool, and a fenced parking area.
A hotel room with a bed, a desk with a computer, a microwave, a red chair, and a window with curtains.
A hotel room with a bed, a desk, a chair, a television, and an air conditioning unit.

5. Red Roof Inn Cameron

Red Roof Inn Cameron
Cameron
$86
$95 total
includes taxes & fees
Oct 4 - Oct 5
Red Roof Inn Cameron
A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining table.
A reception area with a wooden counter, a Mickey Mouse figurine, a large Disney-themed painting, and a ceiling light fixture.
A single-story house with a front porch, a large tree, and a well-maintained lawn.
A neatly made bed with a patterned throw, a bedside lamp, and a small table with a remote control.

6. Hotel Marceline

Hotel Marceline
Marceline
$78
$96 total
includes taxes & fees
Oct 5 - Oct 6
Hotel Marceline
A hotel room with two beds, a desk, a television, and a bathroom visible through an open door.
A hotel with a covered outdoor area, a brick building, and a sign for a nearby Subway.
A cozy room with a coffee machine, a clock, and a potted plant.
A 8 ft. clearance hotel entrance with a SureStay sign, brick exterior, and potted plants.

7. SureStay Hotel by Best Western Cameron

SureStay Hotel by Best Western Cameron
Cameron
$78
$86 total
includes taxes & fees
Oct 9 - Oct 10
SureStay Hotel by Best Western Cameron
A hotel room with a bed, two armchairs, a desk with a chair, a TV, and a painting on the wall.
A Super 8 motel with picnic tables and benches outside.
A hotel room with a wooden desk, a flat-screen TV, a microwave, a refrigerator, a chair, a lamp, and a framed picture on the wall.
A swimming pool with lounge chairs and a hot tub.

8. Super 8 by Wyndham Bethany MO

Super 8 by Wyndham Bethany MO
Bethany
$89
$96 total
includes taxes & fees
Oct 5 - Oct 6
Super 8 by Wyndham Bethany MO
A reception desk with a stone wall backdrop, a wooden door, and a sign indicating a family budget inn.
A hallway with a Coca-Cola vending machine and a snack vending machine.
A row of trucks parked in a gravel lot.
A motel with a brick facade, a covered walkway, and a parking lot.

9. Family Budget Inn Bethany

Family Budget Inn Bethany
Bethany
$63
$68 total
includes taxes & fees
Oct 4 - Oct 5
Family Budget Inn Bethany
A modern kitchen with wooden cabinets, a dishwasher, an oven, and a built-in TV.
A wooden door with a handle, a sign above it, and a hallway with a tiled floor.
A living room with a green sofa, white armchairs, a wooden door, and a view of a house through large windows.
A kitchen with wooden cabinets, a dining table, and a bench.

10. Hamilton Charm Place, 4 Bdrm, 2 Bath, Step-free

Hamilton Charm Place, 4 Bdrm, 2 Bath, Step-free
Hamilton
$212
$383 total
includes taxes & fees
Oct 4 - Oct 5
Hamilton Charm Place, 4 Bdrm, 2 Bath, Step-free
A swimming pool with a hot tub, a ladder, and a slide.
A hotel room with a brown sofa, a wooden coffee table, a desk with a chair, and a lamp. There are three framed pictures on the wall, a window with curtains, and a radiator.
A hotel room with a large bed, two bedside tables with lamps, a desk, and a chair.
A reception area with a reception desk, a plant, a coffee station, and a sign for breakfast.

11. Quality Inn Cameron

Quality Inn Cameron
Cameron
$106
$118 total
includes taxes & fees
Nov 2 - Nov 3
Quality Inn Cameron
A modern living room with a blue sofa, a coffee table, and a fireplace. There is a kitchen area with a red accent wall and a flat-screen TV mounted above the counter.
A SureStay hotel with a blue roof and a green sign.
A reception area with a wooden reception desk, a cityscape painting, a potted plant, and a door in the background.
A hotel room with two beds, a desk, a sofa, a TV, and a window with curtains.

12. SureStay Hotel by Best Western Higginsville

SureStay Hotel by Best Western Higginsville
Higginsville
$71
$77 total
includes taxes & fees
Oct 11 - Oct 12
SureStay Hotel by Best Western Higginsville
A cozy room with a wooden floor, a ceiling fan, a refrigerator, a dining table with chairs, and various potted plants.
A hotel room with two beds, a sofa, a desk, and a chair.
A building with a flat roof and a brick facade, featuring a flagpole and a well-lit entrance.
An outdoor patio area with a grill, table, and chairs, in front of a building with a brick facade and a white awning.

13. Night Inn

Night Inn
Sweet Springs
$88
$100 total
includes taxes & fees
Oct 4 - Oct 5
Night Inn
A hotel room with a large bed, two bedside tables with lamps, a cityscape painting on the wall, and a window with blinds.
A reception area with a stone wall, a large illuminated number '6', and a door to the right.
Reception
A compact kitchenette with a refrigerator, microwave, and a small cabinet with drawers.

14. Motel 6 Concordia, MO

Motel 6 Concordia, MO
Concordia
$60
$70 total
includes taxes & fees
Nov 1 - Nov 2
Motel 6 Concordia, MO
A small indoor swimming pool with a metal ladder, surrounded by white chairs.
A hotel room with a bed, a desk, a chair, a television, and a window.
A breakfast area with a Daybreak sign, ice cube machines, a coffee machine, and a refrigerator.
A multi-story hotel with a prominent brick tower and a flat-roofed annex.

15. Days Inn by Wyndham Concordia

Days Inn by Wyndham Concordia
Concordia
$59
$67 total
includes taxes & fees
Oct 25 - Oct 26
Days Inn by Wyndham Concordia
A lobby with a reception desk, two red chairs, a small table with a lamp, and a large aquarium.
A swimming pool with a clear water surface, a pool ladder, and a few lounge chairs around the pool area.
A building with a covered entrance, multiple windows, and a parking lot.
A hotel room with two beds, a desk, a chair, a lamp, and a television.

16. Comfort Inn Marshall Station

Comfort Inn Marshall Station
Marshall
$117
$133 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Inn Marshall Station
A gazebo with a porch and a picnic table in a grassy field.
A compact hotel room with a wooden desk, a television mounted above it, a white chair, a lamp, a microwave, and a small refrigerator.
A hotel room with a bed, a desk, a microwave, a TV, and a lamp.
A hotel reception area with a curved reception desk, a wall-mounted clock, and a sign for Hotel LexiHill.com.

17. Hotel Lexihill

Hotel Lexihill
Lexington
$64
$70 total
includes taxes & fees
Oct 5 - Oct 6
Hotel Lexihill
A hotel room with two beds, a desk, a chair, a TV, and two wall-mounted lamps.
A hotel reception area with a reception desk, a ceiling fan, a fire extinguisher, and a green wall.
A two-story motel with a covered entrance and a parking lot.
A reception area with a counter, a ceiling fan, a green wall, and a door marked 'EXIT'.

18. Super 8 by Wyndham Sweet Springs

Super 8 by Wyndham Sweet Springs
Sweet Springs
$64
$73 total
includes taxes & fees
Oct 14 - Oct 15
Super 8 by Wyndham Sweet Springs
A gazebo with a metal roof and wooden benches.
A hotel room with a wooden desk, two red chairs, a TV mounted on the wall, a mirror, and a wardrobe.
A hotel room with two beds, a nightstand with a lamp, a small table, a mirror, and a window.
A lobby with a fireplace, a table with four chairs, and a patterned carpet.

19. Econo Lodge Cameron

Econo Lodge Cameron
Cameron
$74
$82 total
includes taxes & fees
Oct 11 - Oct 12
Econo Lodge Cameron
A room with two beds, red walls, and a window with blue curtains.
Room
A living room with a floral sofa, a white door, and a wall-mounted circular mirror.
Exterior

20. Marshall Lodge By OYO Hwy 65

Marshall Lodge By OYO Hwy 65
Marshall
$93
$108 total
includes taxes & fees
Oct 19 - Oct 20
Marshall Lodge By OYO Hwy 65
View all properties

Go beyond your typical stay in Chillicothe

pet friendly image
Pet friendly
Pet friendly
Pool image
Pool
Pool
hot tub image
Hot tub
Hot tub
Family friendly image
Family friendly
Family friendly
Cottage image
Cottage
Cottage
Our prices for hotels in Chillicothe are cheapest in April

Price trends for hotels in Chillicothe

Pricing is based on two traveler single night rates
View properties in October

October

High 19°C / low 9°C. Sunny most days.
19°
9°
11°
2°
5°
-3°
2°
-6°
4°
-5°
11°
2°
17°
7°
22°
13°
28°
19°
30°
20°
29°
19°
26°
15°
Monthly weather averages (˚C)

Top landmarks in Chillicothe

Downtown Greenway

Downtown Greenway is worth a visit when in central Chillicothe.
See properties

Chillicothe Country Club

7.6/10 (7 reviews)
You might want to practice your swing at Chillicothe Country Club, a golf course located 1 mi (1.5 km) from central Chillicothe. If Chillicothe Country Club doesn't quite scratch your golfing itch, Green Hills Golf Course is also nearby.
See properties

Livingston County Library

Livingston County Library is worth a visit when in central Chillicothe.
See properties

Gravesville Park

Gravesville Park is worth a visit, located 0.7 mi (1.2 km) from central Chillicothe.
See properties

Simpson Park

Simpson Park is worth a visit, located 0.9 mi (1.4 km) from central Chillicothe.
See properties

Grand River Historical Society Museum

Grand River Historical Society Museum is 0.5 mi (0.9 km) from central Chillicothe, why not stop by during your stay. If you want to experience more of the culture Chillicothe has to offer, head to Chillicothe Country Club, Downtown Greenway, and Gravesville Park.
See properties

Chillicothe City Hall

Chillicothe City Hall is worth a visit when in central Chillicothe.
See properties

June Shaffer Memorial Park

June Shaffer Memorial Park is worth a visit, located 0.8 mi (1.3 km) from central Chillicothe.
See properties

Chillicothe and related destinations

Grayville is well-known for its attractions such as Grayville Memorial Park and Grayville City Hall. This family-friendly city has something for everyone including sights like Grayville Public Library within a small-town setting.

See all hotels in Grayville
A black and red train with the number 8701 at a train station.

Check out reviews of Chillicothe hotels guests love

A hotel room with a large bathtub, a bed with a headboard, a desk, and a chair.
A spacious living room with a large window, a sofa, a chair, a coffee table, and a lamp.
A reception area with a black and white patterned counter, hanging pendant lights, and a wall-mounted artwork.
A modern kitchen with dark cabinets, a microwave, a juice dispenser, and a decorative wall piece.

Best Western Brookfield

Best Western Brookfield
Brookfield

10/10 Exceptional

United States
Jennifer
Best Western Brookfield
A spacious kitchen with wooden cabinets, a dining area with a table and chairs, and a hallway leading to another room.
A multi-story hotel with a flat roof, a swimming pool, and a fenced parking area.
A hotel room with a bed, a desk with a computer, a microwave, a red chair, and a window with curtains.
A hotel room with a bed, a desk, a chair, a television, and an air conditioning unit.

Red Roof Inn Cameron

Red Roof Inn Cameron
Cameron

10/10 Exceptional

United States
Shannon
Red Roof Inn Cameron
A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining table.
A reception area with a wooden counter, a Mickey Mouse figurine, a large Disney-themed painting, and a ceiling light fixture.
A single-story house with a front porch, a large tree, and a well-maintained lawn.
A neatly made bed with a patterned throw, a bedside lamp, and a small table with a remote control.

Hotel Marceline

Hotel Marceline
Marceline

10/10 Exceptional

United States
Debra
Hotel Marceline
A hotel room with two beds, a desk, a television, and a bathroom visible through an open door.
A hotel with a covered outdoor area, a brick building, and a sign for a nearby Subway.
A cozy room with a coffee machine, a clock, and a potted plant.
A 8 ft. clearance hotel entrance with a SureStay sign, brick exterior, and potted plants.

SureStay Hotel by Best Western Cameron

SureStay Hotel by Best Western Cameron
Cameron

10/10 Exceptional

United States
Dawn
SureStay Hotel by Best Western Cameron
A modern hotel room with a spa area, including a bathtub, a flat-screen TV, and a seating area with ottomans.
A reception desk with a Westbridge logo, a laptop, and a patterned tile design.
A corner room with a jacuzzi, a stone-patterned wall, and a modern light fixture.
A modern kitchen with white cabinets, a refrigerator, a microwave, and a coffee machine. There are two pendant lights hanging above the counter.

Westbridge Inn & Suites Carrollton

Westbridge Inn & Suites Carrollton
Carrollton

10/10 Exceptional

United States
bradley
Westbridge Inn & Suites Carrollton
A hotel room with two beds, a desk, a chair, a TV, and two wall-mounted lamps.
A hotel reception area with a reception desk, a ceiling fan, a fire extinguisher, and a green wall.
A two-story motel with a covered entrance and a parking lot.
A reception area with a counter, a ceiling fan, a green wall, and a door marked 'EXIT'.

Super 8 by Wyndham Sweet Springs

Super 8 by Wyndham Sweet Springs
Sweet Springs

10/10 Exceptional

United States
Cindy
Super 8 by Wyndham Sweet Springs
A hotel room with a bed, two armchairs, a desk with a chair, a TV, and a painting on the wall.
A Super 8 motel with picnic tables and benches outside.
A hotel room with a wooden desk, a flat-screen TV, a microwave, a refrigerator, a chair, a lamp, and a framed picture on the wall.
A swimming pool with lounge chairs and a hot tub.

Super 8 by Wyndham Bethany MO

Super 8 by Wyndham Bethany MO
Bethany

10/10 Exceptional

United States
Jessica
Super 8 by Wyndham Bethany MO
A reception desk with a stone wall backdrop, a wooden door, and a sign indicating a family budget inn.
A hallway with a Coca-Cola vending machine and a snack vending machine.
A row of trucks parked in a gravel lot.
A motel with a brick facade, a covered walkway, and a parking lot.

Family Budget Inn Bethany

Family Budget Inn Bethany
Bethany

10/10 Exceptional

United States
Peggy
Family Budget Inn Bethany
A hotel bathroom with a wooden bathtub, a desk with a lamp, a chair, a television, and a microwave.
A two-story building with a covered parking area and a brick facade.
A reception area with a marble counter, a fish tank, a welcome sign, and a 'Super 8' sign.
A hotel room with a bed, a desk with a computer, a chair, a TV, and a window with a view.

Super 8 by Wyndham Cameron

Super 8 by Wyndham Cameron
Cameron

10/10 Exceptional

United States
Cathy
Super 8 by Wyndham Cameron
A cozy room with a wooden floor, a ceiling fan, a refrigerator, a dining table with chairs, and various potted plants.
A hotel room with two beds, a sofa, a desk, and a chair.
A building with a flat roof and a brick facade, featuring a flagpole and a well-lit entrance.
An outdoor patio area with a grill, table, and chairs, in front of a building with a brick facade and a white awning.

Night Inn

Night Inn
Sweet Springs

10/10 Exceptional

United States
Anonymous traveler
Night Inn
A lobby with a reception desk, two red chairs, a small table with a lamp, and a large aquarium.
A swimming pool with a clear water surface, a pool ladder, and a few lounge chairs around the pool area.
A building with a covered entrance, multiple windows, and a parking lot.
A hotel room with two beds, a desk, a chair, a lamp, and a television.

Comfort Inn Marshall Station

Comfort Inn Marshall Station
Marshall

10/10 Exceptional

United States
Sinsery
Comfort Inn Marshall Station
A spacious living area with a dining table, chairs, a chandelier, and a staircase.
A hotel with a covered entrance, brick facade, and outdoor seating area.
A spacious living room with a large window, a sofa, two armchairs, a dining table, and a rug.
A hotel room with a bed, a desk with a chair, a television, and a bathroom with a bathtub.

Super 8 by Wyndham Richmond

Super 8 by Wyndham Richmond
Richmond

10/10 Exceptional

United States
dci
Super 8 by Wyndham Richmond
A hotel room with a large bed, two bedside tables with lamps, a cityscape painting on the wall, and a window with blinds.
A reception area with a stone wall, a large illuminated number '6', and a door to the right.
Reception
A compact kitchenette with a refrigerator, microwave, and a small cabinet with drawers.

Motel 6 Concordia, MO

Motel 6 Concordia, MO
Concordia

10/10 Exceptional

United States
Marty
Motel 6 Concordia, MO
A modern living room with a blue sofa, a coffee table, and a fireplace. There is a kitchen area with a red accent wall and a flat-screen TV mounted above the counter.
A SureStay hotel with a blue roof and a green sign.
A reception area with a wooden reception desk, a cityscape painting, a potted plant, and a door in the background.
A hotel room with two beds, a desk, a sofa, a TV, and a window with curtains.

SureStay Hotel by Best Western Higginsville

SureStay Hotel by Best Western Higginsville
Higginsville

10/10 Exceptional

United States
Ronald Marsha Niki Natalie
SureStay Hotel by Best Western Higginsville
A hotel room with a desk, two chairs, a sofa, and a patterned carpet.
A hotel dining area with multiple tables and chairs, a kitchen area, and a view of the lobby.
An indoor swimming pool with clear blue water, a covered seating area, and a door with a phone.
A hotel room with a brown leather sofa, a wooden coffee table, and a lamp on a side table. There are framed pictures on the wall and a door in the background.

Quality Inn & Suites Bethany

Quality Inn & Suites Bethany
Bethany

10/10 Exceptional

United States
Patricia
Quality Inn & Suites Bethany
A gazebo with a porch and a picnic table in a grassy field.
A compact hotel room with a wooden desk, a television mounted above it, a white chair, a lamp, a microwave, and a small refrigerator.
A hotel room with a bed, a desk, a microwave, a TV, and a lamp.
A hotel reception area with a curved reception desk, a wall-mounted clock, and a sign for Hotel LexiHill.com.

Hotel Lexihill

Hotel Lexihill
Lexington

10/10 Exceptional

United States
Anonymous traveler
Hotel Lexihill
A reception desk with a "WELCOME" sign, a clock, and a mirror.
A hotel room with two beds, a desk with a chair, a microwave, a TV, and a small shelf with toiletries.
A compact refrigerator with a microwave on top, an air conditioner, and a power outlet on the wall.
A kitchenette with a coffee machine, a trash can, and a sign indicating coffee service hours.

Motel 6 Cameron, MO

Motel 6 Cameron, MO
Cameron

10/10 Exceptional

United States
Terrence
Motel 6 Cameron, MO

Frequently Asked Questions

What accommodations do travelers recommend in Chillicothe?

Guests like Super 8 by Wyndham Chillicothe, Motel 6 – Chillicothe, MO and Fairfield Inn & Suites Chillicothe.

Can I book refundable hotels in Chillicothe?

If you need the flexibility to change your travel plans to Chillicothe, most accommodations provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where should I consider staying in Chillicothe if I want a reasonably priced accommodation?

An inexpensive option worth considering is Comfort Inn & Suites Chillicothe.

What will the weather in Chillicothe be like during my trip?

The warmest months in Chillicothe are usually July and August with an average temp of 74°F. January and February are the chilliest months when the average temp is 34°F. The rainiest months are May and June.

Why should I book my Chillicothe hotel through Hotels.com?

There are plenty of reasons to book your Chillicothe travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.