Business Hotels in Florence

October 2026
6
November 2026

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This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Business Hotels in Florence

1. Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Florence
$127
$146 total
includes taxes & fees
Oct 25 - Oct 26
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

2. Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area
Florence
$98
$112 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Suites Florence Shoals Area

3. Residence Inn Florence Marriott

Residence Inn Florence Marriott
East Florence
$138
$159 total
includes taxes & fees
Oct 15 - Oct 16
Residence Inn Florence Marriott

4. The Stricklin Hotel

The Stricklin Hotel
Florence
$185
$214 total
includes taxes & fees
Nov 4 - Nov 5
The Stricklin Hotel

5. Baymont by Wyndham Florence/Muscle Shoals

Baymont by Wyndham Florence/Muscle Shoals
Florence
$76
$87 total
includes taxes & fees
Oct 7 - Oct 8
Baymont by Wyndham Florence/Muscle Shoals

6. Renaissance Shoals Resort & Spa

Renaissance Shoals Resort & Spa
East Florence
$289
$332 total
includes taxes & fees
Oct 7 - Oct 8
Renaissance Shoals Resort & Spa

7. Clarion Inn Sheffield Muscle Shoals

Clarion Inn Sheffield Muscle Shoals
Sheffield
$79
$89 total
includes taxes & fees
Oct 9 - Oct 10
Clarion Inn Sheffield Muscle Shoals

8. Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
Tuscumbia
$63
$70 total
includes taxes & fees
Oct 20 - Oct 21
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

9. Spark by Hilton Tuscumbia Muscle Shoals

Spark by Hilton Tuscumbia Muscle Shoals
Tuscumbia
$90
$100 total
includes taxes & fees
Nov 1 - Nov 2
Spark by Hilton Tuscumbia Muscle Shoals

10. Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
Tuscumbia
$112
$123 total
includes taxes & fees
Oct 10 - Oct 11
Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

11. Comfort Inn & Suites Tuscumbia - Muscle Shoals

Comfort Inn & Suites Tuscumbia - Muscle Shoals
Tuscumbia
$106
$117 total
includes taxes & fees
Oct 18 - Oct 19
Comfort Inn & Suites Tuscumbia - Muscle Shoals

12. Red Roof Inn Muscle Shoals

Red Roof Inn Muscle Shoals
Muscle Shoals
$80
$89 total
includes taxes & fees
Oct 7 - Oct 8
Red Roof Inn Muscle Shoals

13. Keywest Inn - Tuscumbia/Muscle Shoals

Keywest Inn - Tuscumbia/Muscle Shoals
Tuscumbia
$75
$83 total
includes taxes & fees
Oct 7 - Oct 8
Keywest Inn - Tuscumbia/Muscle Shoals
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Top neighborhoods in Florence

East Florence

Florence's East Florence neighborhood has a host of places to visit such as Wilson Lake and Tennessee River.

Top landmarks in Florence

McFarland Park

McFarland Park is worth a visit, located 1.1 mi (1.7 km) from central Florence.
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Regency Square Mall

7.8/10 (96 reviews)
If you like shopping, take time out to go to Regency Square Mall when in Florence.
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Shoals Conference Center

6.4/10 (10 reviews)
Shoals Conference Center is worth a pic or two when discovering East Florence.
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Shoals Community Theater

7.6/10 (13 reviews)
If you’re after a show while in the center of Florence, you might want to get tickets at Shoals Community Theater. If you want to experience more of the culture Florence has to offer, head to University of North Alabama, McFarland Park, and North Alabama Medical Center.
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Blackberry Trail Golf Course

7.8/10 (22 reviews)
You might want to play some rounds at Blackberry Trail Golf Course, located 5.1 mi (8.2 km) from central Florence. If Blackberry Trail Golf Course doesn't quite scratch your golfing itch, Shoals Golf Club is just a short drive away.
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Kennedy-Douglass Center for the Arts

8.2/10 (38 reviews)
Kennedy-Douglass Center for the Arts is in the heart of Florence, so why not stop by during your stay. If you have fun at Kennedy-Douglass Center for the Arts, you'll love Muscle Shoals Sound Studios and Children's Museum of the Shoals, both located nearby.
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Key Cave National Wildlife Refuge

Key Cave National Wildlife Refuge is 6.8 mi (11 km) from central Florence, why not stop by during your stay. Want to stretch your legs some more? Head to Spring Park and Sevenmile Island Wildlife Management Area, both nearby.
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Children's Museum of the Shoals

7.2/10 (7 reviews)
Children's Museum of the Shoals is 3.3 mi (5.3 km) from central Florence, why not stop by during your stay. If you want to experience more of the culture Florence has to offer, head to Regency Square Mall, North Alabama Medical Center, and University of North Alabama.
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About the destination

Florence is a family-friendly place known for its restaurants. Nature lovers can visit Wilson Lake and Pickwick Lake. And while you're here, be sure to stop by Shoals Conference Center and Regency Square Mall.