Hotels in Florence
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Tonight
Sep 2 - Sep 3Tomorrow
Sep 3 - Sep 4This weekend
Sep 4 - Sep 6Next weekend
Sep 11 - Sep 13Where to stay in Florence?
1. Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SCFlorence
$80
$89 total
includes taxes & fees
Sep 7 - Sep 8
2. Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham FlorenceFlorence
$65
$72 total
includes taxes & fees
Sep 3 - Sep 4
3. Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center AreaFlorence
$108
$121 total
includes taxes & fees
Sep 27 - Sep 28
4. Hyatt Place Florence Downtown
Hyatt Place Florence DowntownFlorence
$100
$112 total
includes taxes & fees
Sep 8 - Sep 9
5. Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic CenterFlorence
$88
$98 total
includes taxes & fees
Oct 1 - Oct 2
6. Spark by Hilton Florence North I-95, SC
Spark by Hilton Florence North I-95, SCFlorence
$93
$109 total
includes taxes & fees
Sep 13 - Sep 14
7. Comfort Suites Florence I-95
Comfort Suites Florence I-95Florence
$85
$100 total
includes taxes & fees
Sep 28 - Sep 29
8. SpringHill Suites by Marriott Florence
SpringHill Suites by Marriott FlorenceFlorence
$104
$122 total
includes taxes & fees
Sep 11 - Sep 12
9. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHGFlorence
$118
$142 total
includes taxes & fees
Sep 7 - Sep 8
10. La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham FlorenceFlorence
$89
$100 total
includes taxes & fees
Sep 13 - Sep 14
11. Home2 Suites by Hilton Florence, SC
Home2 Suites by Hilton Florence, SCFlorence
$101
$117 total
includes taxes & fees
Sep 27 - Sep 28
12. Hampton Inn & Suites Florence Center
Hampton Inn & Suites Florence CenterFlorence
$110
$123 total
includes taxes & fees
Sep 20 - Sep 21
13. Homewood Suites by Hilton Florence
Homewood Suites by Hilton FlorenceFlorence
$107
$130 total
includes taxes & fees
Sep 20 - Sep 21
14. Tru by Hilton Florence I-95
Tru by Hilton Florence I-95Florence
$98
$115 total
includes taxes & fees
Sep 8 - Sep 9
15. Hotel Florence, Tapestry Collection by Hilton
Hotel Florence, Tapestry Collection by HiltonFlorence
$139
$155 total
includes taxes & fees
Sep 11 - Sep 12
16. Hilton Garden Inn Florence
Hilton Garden Inn FlorenceFlorence
$114
$128 total
includes taxes & fees
Sep 13 - Sep 14
17. Staybridge Suites Florence - Civic Center by IHG
Staybridge Suites Florence - Civic Center by IHGFlorence
$135
$151 total
includes taxes & fees
Sep 13 - Sep 14
18. TownePlace Suites by Marriott Florence
TownePlace Suites by Marriott FlorenceFlorence
$114
$128 total
includes taxes & fees
Sep 10 - Sep 11
19. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHGFlorence
$126
$141 total
includes taxes & fees
Sep 30 - Oct 1
20. Residence Inn Marriott Florence
Residence Inn Marriott FlorenceFlorence
$107
$120 total
includes taxes & fees
Sep 13 - Sep 14
Get last-minute hotel deals in Florence and save more
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$65
per night
$72 total
includes taxes & fees
$96
per night
$108 total
includes taxes & fees
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHGFlorence
$154
per night
$182 total
includes taxes & fees
$124
per night
$145 total
includes taxes & fees
$109
per night
$122 total
includes taxes & fees
$69
per night
$77 total
includes taxes & fees
$133
per night
$149 total
includes taxes & fees
$144
per night
$161 total
includes taxes & fees
$34 off
The Inn at the Crossroads$99
per night
$111 total
includes taxes & fees
Fairfield Inn & Suites by Marriott Florence I-20
Fairfield Inn & Suites by Marriott Florence I-20Florence
$169
per night
$189 total
includes taxes & fees
$85
per night
$95 total
includes taxes & fees
$73
per night
$82 total
includes taxes & fees
$149
per night
$173 total
includes taxes & fees
$54
per night
$60 total
includes taxes & fees
$159
per night
$184 total
includes taxes & fees
Check out pet-friendly hotels in Florence
$80
$89 total
includes taxes & fees
Sep 7 - Sep 8
$108
$121 total
includes taxes & fees
Sep 27 - Sep 28
$88
$98 total
includes taxes & fees
Oct 1 - Oct 2
$85
$100 total
includes taxes & fees
Sep 28 - Sep 29
$93
$109 total
includes taxes & fees
Sep 13 - Sep 14
$104
$122 total
includes taxes & fees
Sep 11 - Sep 12
$100
$112 total
includes taxes & fees
Sep 8 - Sep 9
$110
$123 total
includes taxes & fees
Sep 20 - Sep 21
$101
$117 total
includes taxes & fees
Sep 27 - Sep 28
$89
$100 total
includes taxes & fees
Sep 13 - Sep 14
You may also like hotels with pools in Florence
$80
$89 total
includes taxes & fees
Sep 7 - Sep 8
$88
$98 total
includes taxes & fees
Oct 1 - Oct 2
$100
$112 total
includes taxes & fees
Sep 8 - Sep 9
$108
$121 total
includes taxes & fees
Sep 27 - Sep 28
$93
$109 total
includes taxes & fees
Sep 13 - Sep 14
$85
$100 total
includes taxes & fees
Sep 28 - Sep 29
$104
$122 total
includes taxes & fees
Sep 11 - Sep 12
$110
$123 total
includes taxes & fees
Sep 20 - Sep 21
$98
$115 total
includes taxes & fees
Sep 8 - Sep 9
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHGFlorence
$126
$141 total
includes taxes & fees
Sep 30 - Oct 1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Florence
Pet friendly
Family friendly
Cottage
Our prices for hotels in Florence are cheapest in December
Our prices for hotels in Florence are cheapest in December
Price trends for hotels in Florence
Pricing is based on two traveler single night rates
Top landmarks in Florence
Florence Civic Center
8.0/10 (599 reviews)
Florence Civic Center is worth a visit, located 4.1 mi (6.6 km) from central Florence.
Magnolia Mall
8.2/10 (745 reviews)
If you like shopping, take time out to go to Magnolia Mall when in Florence.
Florence County Museum
7.8/10 (236 reviews)
The center of Florence is home to cultural attractions like Florence County Museum, so you might want to stop by during your stay. If you want to experience more of the culture Florence has to offer, head to Mcleod Regional Medical Center, Magnolia Mall, and Florence Civic Center.
Palmetto Shores Lake
7.4/10 (96 reviews)
Palmetto Shores Lake is 5.2 mi (8.3 km) from central Florence, why not stop by during your stay.
Eastern Carolina Agricultural Fairgrounds
7.4/10 (162 reviews)
Why not give yourself a treat with a trip to Eastern Carolina Agricultural Fairgrounds, one of the family attractions located 7.3 mi (11.8 km) from central Florence. If you'd also like to explore some of the parks in Florence, head to Greenwood Baseball Park and Playground.
Dr. Eddie Floyd Tennis Center
You can catch an event at Dr. Eddie Floyd Tennis Center, located 1.6 mi (2.6 km) from central Florence.
If you think Dr. Eddie Floyd Tennis Center is cool, you also might like CarolinaBank Field, located nearby.
Columns Plantation
7.6/10 (101 reviews)
If you're planning a bit of sightseeing during your trip, head to Columns Plantation— just one of the landmarks located 7.3 mi (11.8 km) from central Florence.
Florence Veterans Park
8.0/10 (58 reviews)
If seeing the sights is on your list of things to do, head to Florence Veterans Park— just one of the landmarks located 3.9 mi (6.2 km) from central Florence. If you like Florence Veterans Park, you'll love Greenwood Baseball Park and Playground and Williamson Park, both just a short drive away.
Florence and related destinations
Between the intersections of two major highways lies a city where history and Southern culture blend seamlessly. The Florence County Museum showcases local heritage, while the War Between the States Museum offers a window into Civil War history. Downtown restaurants serve up authentic Southern cuisine worth the detour off I-95. Catch performances at Francis Marion University's Performing Arts Center, with acoustics rivaling larger cities. Florence Veterans Park provides a peaceful retreat with thoughtful memorials. Shoppers enjoy Magnolia Mall, while families visit Greenwood Baseball Park's playgrounds. The city's railroad heritage remains visible in its layout – a reminder of how this transportation hub became the beating heart of the Pee Dee region.
See all hotels in Florence
Check out reviews of Florence hotels guests love
TownePlace Suites by Marriott Florence
10/10 Excellent
"Staff was accommodating and very nice. The room is very clean and quiet"
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
10/10 Excellent
"Clean"
Comfort Inn & Suites Florence Center Area
8/10 Good
"Na"
Hyatt Place Florence Downtown
10/10 Excellent
"A wonderful place to stay with really good breakfast!!!"
Tru by Hilton Florence I-95
10/10 Excellent
"I"
Days Inn by Wyndham Florence Near Civic Center
8/10 Good
"Good"
Hampton Inn & Suites Florence Center
10/10 Excellent
"We really enjoyed our stay."
Comfort Suites Florence I-95
8/10 Good
"Nice hotel. Just disappointed that the inside pool water is too cold to swim in. I asked before I booked if the pool water was warm and was told yes but once again it was cold and couldn’t swim."
Hampton Inn & Suites Florence-North-I-95
10/10 Excellent
"The only issue that I had was the pool was out of order. I stayed there back in November of 2025, and the pool was out of order then!!"