Hotels in Florence
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Affordable Suites Florence
Affordable Suites Florencecleanliness Florence stay with spacious rooms and helpful staff near Veterans Park.

Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center Areacleanliness Sink into comfortable beds near Florence Veterans Park with a seasonal pool.

Hyatt Place Florence Downtown
Hyatt Place Florence Downtowncleanliness Stay comfortably near Florence attractions with an outdoor pool and 24-hour fitness center.

TownePlace Suites by Marriott Florence
TownePlace Suites by Marriott Florencecleanliness Spacious Florence hotel with outdoor pool and 24-hour fitness center near Veterans Park.

Staybridge Suites Florence - Civic Center by IHG
Staybridge Suites Florence - Civic Center by IHGcleanliness Relax at this Florence hotel with outdoor pool and spacious suites for families.

Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SCcleanliness Stay near Florence Station with free breakfast, WiFi, and 24-hour fitness center.

Residence Inn Marriott Florence
Residence Inn Marriott Florencecleanliness Bright Florence stay near Magnolia Mall with fitness center and outdoor pool.

Aloft Florence
Aloft Florencecleanliness Wake up to convenience at this modern Florence hotel with an indoor pool.

SpringHill Suites by Marriott Florence
SpringHill Suites by Marriott Florencecleanliness Peaceful hotel with convenient location for dining and shopping in Florence.

Hotel Florence, Tapestry Collection by Hilton
Hotel Florence, Tapestry Collection by Hiltoncleanliness Take in serene surroundings at this spa hotel near Florence Station.

Hampton Inn & Suites Florence-North-I-95
Hampton Inn & Suites Florence-North-I-95cleanliness Cozy Florence retreat with hot tub, fitness center, and complimentary treats.

Fairfield Inn by Marriott Hartsville
Fairfield Inn by Marriott Hartsvillecleanliness Peaceful retreat in Hartsville near dining and shopping with pool and fitness center.

Homewood Suites by Hilton Florence
Homewood Suites by Hilton Florencecleanliness Seasonal outdoor pool and 24-hour fitness center in Florence with free breakfast.

The Mantissa Hotel
The Mantissa Hotelcleanliness Scenic Hartsville views await on the rooftop terrace at this welcoming hotel.

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHGcleanliness Relaxing gateway to I-95 travelers with indoor pool and complimentary perks.

Home2 Suites by Hilton Florence, SC
Home2 Suites by Hilton Florence, SC
Tru by Hilton Florence I-95
Tru by Hilton Florence I-95cleanliness Casual Florence hotel near Darlington Raceway with pool and complimentary perks.

Hampton Inn & Suites Hartsville
Hampton Inn & Suites Hartsvillecleanliness Relax in this hotel near Hartsville Museum with pool and fitness center.

La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florencecleanliness Experience comfort near highways and popular dining spots in peaceful Florence.

Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florencecleanliness Convenient Florence stay with free parking near Darlington Raceway.
Check out pet-friendly hotels in Florence

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Go beyond your typical stay in Florence
Top landmarks in Florence
Florence and related destinations
Between the intersections of two major highways lies a city where history and Southern culture blend seamlessly. The Florence County Museum showcases local heritage, while the War Between the States Museum offers a window into Civil War history. Downtown restaurants serve up authentic Southern cuisine worth the detour off I-95. Catch performances at Francis Marion University's Performing Arts Center, with acoustics rivaling larger cities. Florence Veterans Park provides a peaceful retreat with thoughtful memorials. Shoppers enjoy Magnolia Mall, while families visit Greenwood Baseball Park's playgrounds. The city's railroad heritage remains visible in its layout – a reminder of how this transportation hub became the beating heart of the Pee Dee region.

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