Hotels in Florence
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Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHGcleanliness Relaxing gateway to I-95 travelers with indoor pool and complimentary perks.

Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florencecleanliness Convenient Florence stay with free parking near Darlington Raceway.

Best Western Inn
Best Western Inncleanliness Restful stay in this well-located Florence hotel with helpful, attentive staff.

Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SCcleanliness Stay near Florence Station with free breakfast, WiFi, and 24-hour fitness center.

Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center Areacleanliness Sink into comfortable beds near Florence Veterans Park with a seasonal pool.

Microtel Inn & Suites by Wyndham Florence
Microtel Inn & Suites by Wyndham Florencecleanliness Easy access to I-95 makes this hotel a convenient stop for business travelers.

Super 8 by Wyndham Florence
Super 8 by Wyndham Florencecleanliness Just outside Florence's center with easy highway access and a seasonal pool.

Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Centercleanliness Tranquil retreat near Magnolia Mall with seasonal pool and free amenities.

Tru by Hilton Florence I-95
Tru by Hilton Florence I-95cleanliness Casual Florence hotel near Darlington Raceway with pool and complimentary perks.

La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florencecleanliness Experience comfort near highways and popular dining spots in peaceful Florence.

Holiday Inn Express & Suites Latta by IHG
Holiday Inn Express & Suites Latta by IHGcleanliness Seasonal pool and free breakfast add value to your Florence-adjacent stay.

Home2 Suites by Hilton Florence, SC
Home2 Suites by Hilton Florence, SC
Best Western Executive Inn
Best Western Executive Inncleanliness Quiet retreat with pool access in Latta, just 22 minutes from Florence Regional.

Fairfield Inn & Suites by Marriott Florence I-20
Fairfield Inn & Suites by Marriott Florence I-20cleanliness Fitness-focused hotel near Florence Veterans Park with indoor pool and friendly staff.

Hyatt Place Florence Downtown
Hyatt Place Florence Downtowncleanliness Stay comfortably near Florence attractions with an outdoor pool and 24-hour fitness center.

Spark by Hilton Florence North I-95, SC
Spark by Hilton Florence North I-95, SC
Red Roof Inn Dillon, SC
Red Roof Inn Dillon, SCcleanliness Budget-friendly oasis in Dillon with free breakfast and convenient highway access.

Quality Inn Dillon
Quality Inn Dilloncleanliness Peaceful retreat in Dillon with free breakfast and nearby attractions.

Hampton Inn & Suites Florence-North-I-95
Hampton Inn & Suites Florence-North-I-95cleanliness Cozy Florence retreat with hot tub, fitness center, and complimentary treats.

The Inn at the Crossroads
The Inn at the Crossroadscleanliness Enjoy Lake City Bistro while staying minutes from Lynches Lake and The Bean Market.
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Go beyond your typical stay in Florence
Top landmarks in Florence
Florence and related destinations
Between the intersections of two major highways lies a city where history and Southern culture blend seamlessly. The Florence County Museum showcases local heritage, while the War Between the States Museum offers a window into Civil War history. Downtown restaurants serve up authentic Southern cuisine worth the detour off I-95. Catch performances at Francis Marion University's Performing Arts Center, with acoustics rivaling larger cities. Florence Veterans Park provides a peaceful retreat with thoughtful memorials. Shoppers enjoy Magnolia Mall, while families visit Greenwood Baseball Park's playgrounds. The city's railroad heritage remains visible in its layout – a reminder of how this transportation hub became the beating heart of the Pee Dee region.

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