A coastal cityscape with a sandy beach, palm trees, and high-rise buildings.

5 Star Hotels in Panama City

Where to?

Dates

November 2026

December 2026

I'm traveling for business

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

5 Star Hotels in Panama City

A bar area with a view of the sunset over the water, equipped with bar stools and a variety of bottles.

1. Hotel Indigo Panama City Marina by IHG

Downtown Panama City

$133 total

includes taxes & fees

Nov 23 - Nov 24

A hotel with a central tower, multiple buildings, and a parking area.

2. La Quinta Inn & Suites by Wyndham Panama City

Panama City

$63 total

includes taxes & fees

Nov 22 - Nov 23

A spacious indoor area with a central water feature surrounded by planters, large windows offering views of the sea, and a modern architectural design.

3. Hyatt Place Panama City Beach

Panama City Beach

$105 total

includes taxes & fees

Nov 9 - Nov 10

A modern lobby with a reception desk, seating area, and a green wall with plants.

4. Holiday Inn Panama City by IHG

Panama City

$121 total

includes taxes & fees

Dec 2 - Dec 3

An outdoor patio with a fire pit, seating, and a covered area with string lights.

5. Hilton Garden Inn Panama City Airport

Panama City

$119 total

includes taxes & fees

Dec 1 - Dec 2

A Courtyard by Marriott hotel with a central courtyard, multiple floors, and a well-lit entrance.

6. Courtyard by Marriott Panama City

Panama City

$105 total

includes taxes & fees

Dec 3 - Dec 4

A modern coffee shop interior with a counter, seating area, and various food items displayed.

7. Hilton Garden Inn Panama City

Panama City

$106 total

includes taxes & fees

Nov 22 - Nov 23

A covered outdoor area with seating and a view of the ocean.

8. Embassy Suites by Hilton Panama City Beach Resort

Panama City Beach

$140 total

includes taxes & fees

Nov 15 - Nov 16

A modern building with a covered outdoor seating area, a fire pit, and a barbecue grill.

9. Candlewood Suites Panama City Tyndall AFB by IHG

Panama City

$122 total

includes taxes & fees

Nov 10 - Nov 11

A modern hotel room with a large bed, a desk, a chair, a sofa, and a television.

10. Atwell Suites Panama City Beach Southeast by IHG

Panama City Beach

$74 total

includes taxes & fees

Dec 2 - Dec 3

A swimming pool with lounge chairs and umbrellas, surrounded by buildings with balconies and a waterfall feature.

11. Holiday Inn Express & Suites Panama City Beach - Beachfront by IHG

Panama City Beach

$139 total

includes taxes & fees

Nov 10 - Nov 11

A resort pool with lounge chairs and umbrellas, a beach view, and a pier in the background.

12. SpringHill Suites by Marriott Panama City Beach Beachfront

Panama City Beach

$106 total

includes taxes & fees

Nov 19 - Nov 20

A spacious lobby with a grey sofa, round coffee table, and a patterned rug.

13. Wingate by Wyndham Panama City Area Lynn Haven

Lynn Haven

$95 total

includes taxes & fees

Dec 1 - Dec 2

A resort with a beachfront pool, palm trees, and a white building with balconies.

14. Holiday Inn Resort Panama City Beach by IHG

Panama City Beach

$149 total

includes taxes & fees

Nov 22 - Nov 23

A modern reception area with a counter, a refrigerator stocked with beverages, and a seating area with a table and chairs.

15. Comfort Inn & Suites Panama City Beach - Pier Park Area

Panama City Beach

$77 total

includes taxes & fees

Nov 11 - Nov 12

A modern hotel with a prominent neon sign, large columns, and a well-lit entrance.

16. Hampton Inn & Suites Panama City Beach-Pier Park Area

Panama City Beach

$96 total

includes taxes & fees

Nov 10 - Nov 11

TownePlace Suites by Marriott with a parking lot, accessible entrance, and a building facade with a mix of beige and red colors.

17. TownePlace Suites by Marriott Panama City

Panama City

$110 total

includes taxes & fees

Nov 29 - Nov 30

A resort with multiple swimming pools, a parking area, and a body of water.

18. Hilton Vacation Club Bayside Resort Panama City Beach

Panama City Beach

$151 total

includes taxes & fees

Nov 6 - Nov 7

A lobby with a reception desk, a chandelier, a sofa, and a potted plant.

19. Comfort Inn & Suites Panama City North

Panama City

$75 total

includes taxes & fees

Nov 22 - Nov 23

A modern lounge area with comfortable seating, a flat-screen TV, and a view of the outside.

20. Best Western Plus Panama City Hotel

Panama City

$82 total

includes taxes & fees

Nov 6 - Nov 7

View all properties

Top neighborhoods in Panama City

A flagpole with the American flag, palm trees, and a sign that reads "Panama City Marina".

Downtown Panama City

Downtown Panama City balances historic charm with waterfront beauty along St. Andrews Bay. The Victorian-era McKenzie House and brick-faced Martin Theatre showcase the area's rich past. Stroll along waterfront promenades where pelicans dive and sailboats bob in emerald waters, or catch rotating exhibitions at the Panama City Center for the Arts. Waterfront seafood restaurants serve fresh Gulf shrimp and grouper with bay views. Boutique hotels in restored buildings and historic bed & breakfasts offer personalized stays with period furnishings. The compact downtown core is easily walkable with brick sidewalks connecting attractions, shops, and the marina.

See properties

A dolphin jumping out of the water with a boat in the background.

St. Andrews

St. Andrews blends coastal charm with maritime history along Panama City's bayfront. The historic district's Victorian buildings and the restored 1913 Panama City Publishing Company Museum showcase the neighborhood's rich heritage. Stroll waterfront paths with Gulf Coast views, browse the farmers market for local seafood, or watch boats bobbing in St. Andrews Marina. Fresh Gulf seafood stars at casual waterfront restaurants where you can enjoy grouper sandwiches with bay views. Boutique inns and historic bed & breakfasts in restored Victorian homes offer personalized service. The walkable core connects the marina, shops, and tree-lined streets, making it perfect for leisurely exploration.

See properties

Millville

See properties

A building with a sign reading "MacArthur Ave" and "Emergency and Trauma Center" on the side.

Bunkers Cove

Bunkers Cove gives you a front-row seat to St. Andrews Bay without the tourist chaos. This upscale residential area lets you live like a well-heeled local with waterfront views and peaceful streets perfect for evening strolls. When you're ready to explore, the Cove Shopping Center, Visual Arts Center, and Martin Theatre are just minutes away. Getting around requires wheels—bring your car or budget for rideshares to reach Panama City's restaurants and attractions. Accommodation here means luxury vacation rentals with private docks and bay access rather than hotels. The payoff? Quiet mornings watching boats drift by and the perfect launch spot for kayaking adventures.

See properties

Glenwood

See properties

Top landmarks in Panama City

A marina with several boats docked, a pier extending into the water, and palm trees along the shore.

Panama City Marina

8.4/10 (468 reviews)

You can stroll along Panama City Marina for relaxing water views when you're in Downtown Panama City. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.

See properties

A calm water body reflecting palm trees and a clear sky.

Majette Dunes Disc Golf Course

7.4/10 (16 reviews)

You might want to practice your swing at Majette Dunes Golf & Country Club, a golf course located 10.9 mi (17.6 km) from central Panama City. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches. If Majette Dunes Golf & Country Club doesn't quite scratch your golfing itch, Fox Run Country Club is just a short drive away.

See properties