Hotels in Pickens
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Pickens?
Days Inn by Wyndham Easley/Greenville/Clemson Area
Days Inn by Wyndham Easley/Greenville/Clemson Area
2.0 star property
Easley
6.2 out of 10, (821)
6.2/10
(821)
The price is $65
$65
$72 total
includes taxes & fees
Dec 22 - Dec 23
Baymont by Wyndham Easley/Greenville
Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (756)
7.4/10
Good
(756)
The price is $75
$75
$83 total
includes taxes & fees
Dec 22 - Dec 23
Quality Inn & Suites Easley - Greenville
Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (387)
7.0/10
Good
(387)
The price is $52
$52
$58 total
includes taxes & fees
Dec 27 - Dec 28
Hampton Inn Easley
Hampton Inn Easley
2.5 star property
Easley
9.4 out of 10, Exceptional, (683)
9.4/10
Exceptional
(683)
The price is $139
$139
$154 total
includes taxes & fees
Dec 27 - Dec 28
The Inn at Patrick Square
The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (784)
9.8/10
Exceptional
(784)
The price is $149
$149
$165 total
includes taxes & fees
Dec 22 - Dec 23
Courtyard Marriott Clemson
Courtyard Marriott Clemson
3.0 star property
Clemson
9.0 out of 10, Wonderful, (523)
9.0/10
Wonderful
(523)
The price is $107
$107
$119 total
includes taxes & fees
Dec 27 - Dec 28
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1005)
8.2/10
Very Good
(1005)
The price is $84
$84
$93 total
includes taxes & fees
Dec 23 - Dec 24
Days Inn by Wyndham Clemson
Days Inn by Wyndham Clemson
3.5 star property
Clemson
6.8 out of 10, (198)
6.8/10
(198)
The price is $85
$85
$94 total
includes taxes & fees
Dec 23 - Dec 24
Inn @ Clemson
Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very Good, (1002)
8.0/10
Very Good
(1002)
The price is $89
$89
$99 total
includes taxes & fees
Dec 22 - Dec 23
Holiday Inn Express & Suites Clemson by IHG
Holiday Inn Express & Suites Clemson by IHG
2.5 star property
Clemson
8.8 out of 10, Excellent, (950)
8.8/10
Excellent
(950)
The price is $108
$108
$120 total
includes taxes & fees
Jan 2 - Jan 3, 2026
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (743)
9.8/10
Exceptional
(743)
The price is $169
$169
$188 total
includes taxes & fees
Dec 22 - Dec 23
Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very Good, (1001)
8.2/10
Very Good
(1001)
The price is $98
$98
$109 total
includes taxes & fees
Dec 29 - Dec 30
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1003)
9.0/10
Wonderful
(1003)
The price is $109
$109
$135 total
includes taxes & fees
Dec 22 - Dec 23
Hampton Inn Clemson-University Area
Hampton Inn Clemson-University Area
2.5 star property
Clemson
8.8 out of 10, Excellent, (623)
8.8/10
Excellent
(623)
The price is $101
$101
$112 total
includes taxes & fees
Dec 29 - Dec 30
The Abernathy of Clemson
The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (557)
9.6/10
Exceptional
(557)
The price is $149
$149
$165 total
includes taxes & fees
Dec 26 - Dec 27
Clemson Memorabilia House
Clemson Memorabilia House
3.0 star property
Clemson
9.8 out of 10, Exceptional, (9)
9.8/10
Exceptional
(9)
The price is $89
$89
$238 total
includes taxes & fees
Dec 22 - Dec 23
Comfort Suites Piedmont - Greenville South
Comfort Suites Piedmont - Greenville South
2.5 star property
Piedmont
8.6 out of 10, Excellent, (926)
8.6/10
Excellent
(926)
The price is $107
$107
$118 total
includes taxes & fees
Dec 29 - Dec 30
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (795)
9.2/10
Wonderful
(795)
The price is $98
$98
$107 total
includes taxes & fees
Dec 27 - Dec 28
Homewood Suites by Hilton Greenville Downtown
Homewood Suites by Hilton Greenville Downtown
3.0 star property
Greenville Downtown
9.4 out of 10, Exceptional, (1006)
9.4/10
Exceptional
(1006)
The price is $119
$119
$135 total
includes taxes & fees
Dec 28 - Dec 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Budget hotels in Pickens and vicinity
Quality Inn & Suites Easley - Greenville
Quality Inn & Suites Easley - Greenville2.5 star property
Easley
7.0 out of 10, Good, (387)
7.0/10
Good
(387)
The price is $52
$52
$58 total
includes taxes & fees
Dec 27 - Dec 28
Motel 6 Greenville, SC - I-85 Near Downtown
Motel 6 Greenville, SC - I-85 Near Downtown2.0 star property
Greenville
7.0 out of 10, Good, (349)
7.0/10
Good
(349)
The price is $56
$56
$62 total
includes taxes & fees
Jan 5 - Jan 6, 2026
7.0 out of 10, Good, (844)
7.0/10
Good
(844)
The price is $60
$60
$66 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Urban Boutique Hotel, BW Signature Collection
Urban Boutique Hotel, BW Signature Collection2.5 star property
Greenville
8.0 out of 10, Very Good, (929)
8.0/10
Very Good
(929)
The price is $62
$62
$68 total
includes taxes & fees
Jan 4 - Jan 5, 2026
7.8 out of 10, Good, (1001)
7.8/10
Good
(1001)
The price is $63
$63
$70 total
includes taxes & fees
Dec 23 - Dec 24
7.8 out of 10, Good, (316)
7.8/10
Good
(316)
The price is $65
$65
$72 total
includes taxes & fees
Dec 22 - Dec 23
Quality Inn & Suites Greenville - Haywood Mall
Quality Inn & Suites Greenville - Haywood Mall2.5 star property
Greenville
7.4 out of 10, Good, (1005)
7.4/10
Good
(1005)
The price is $67
$67
$76 total
includes taxes & fees
Dec 22 - Dec 23
WoodSpring Suites Greenville Haywood Mall
WoodSpring Suites Greenville Haywood Mall2.5 star property
Greenville
7.6 out of 10, Good, (261)
7.6/10
Good
(261)
The price is $67
$67
$74 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Quality Inn & Suites Greenville near downtown
Quality Inn & Suites Greenville near downtown2.5 star property
Greenville
7.0 out of 10, Good, (705)
7.0/10
Good
(705)
The price is $67
$67
$74 total
includes taxes & fees
Dec 23 - Dec 24
La Quinta Inn & Suites by Wyndham Greenville Haywood
La Quinta Inn & Suites by Wyndham Greenville Haywood3.0 star property
Greenville
7.4 out of 10, Good, (1123)
7.4/10
Good
(1123)
The price is $68
$68
$75 total
includes taxes & fees
Dec 28 - Dec 29
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd2.0 star property
Greenville
8.2 out of 10, Very Good, (1005)
8.2/10
Very Good
(1005)
The price is $69
$69
$76 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Holiday Inn Express Brevard City Center by IHG
Holiday Inn Express Brevard City Center by IHG2.5 star property
Brevard
9.2 out of 10, Wonderful, (603)
9.2/10
Wonderful
(603)
The price is $70
$70
$78 total
includes taxes & fees
Dec 28 - Dec 29
Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-1232.5 star property
Downtown
8.0 out of 10, Very Good, (665)
8.0/10
Very Good
(665)
The price is $74
$74
$87 total
includes taxes & fees
Dec 27 - Dec 28
9.2 out of 10, Wonderful, (510)
9.2/10
Wonderful
(510)
The price is $74
$74
$83 total
includes taxes & fees
Dec 22 - Dec 23
7.6 out of 10, Good, (62)
7.6/10
Good
(62)
The price is $72
$72
$80 total
includes taxes & fees
Dec 22 - Dec 23
7.4 out of 10, Good, (756)
7.4/10
Good
(756)
The price is $75
$75
$83 total
includes taxes & fees
Dec 22 - Dec 23
7.6 out of 10, Good, (174)
7.6/10
Good
(174)
The price is $75
$75
$84 total
includes taxes & fees
Dec 22 - Dec 23
Studio 6 Suites Greenville, SC - Haywood Mall
Studio 6 Suites Greenville, SC - Haywood Mall2.0 star property
Greenville
7.0 out of 10, Good, (541)
7.0/10
Good
(541)
The price is $75
$75
$82 total
includes taxes & fees
Dec 22 - Dec 23
8.6 out of 10, Excellent, (1002)
8.6/10
Excellent
(1002)
The price is $76
$76
$84 total
includes taxes & fees
Dec 28 - Dec 29
7.2 out of 10, Good, (147)
7.2/10
Good
(147)
The price is $76
$76
$85 total
includes taxes & fees
Dec 28 - Dec 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Pickens
Pet friendly
Cottage
Family friendly
Apartment
Top landmarks in Pickens
Table Rock State Park Headquarters and Visitor Center
Table Rock State Park Headquarters and Visitor Center is 9.5 mi (15.2 km) from central Pickens, why not stop by during your stay. If you like Table Rock State Park Headquarters and Visitor Center, you'll love Mountain Bridge Wilderness Area and Pickens Recreation Center, both just a short drive away.
The Real American Tea Museum
If museums are on your list of things to see in Pickens, then you might want to head to The Real American Tea Museum. If you want to experience more of the culture Pickens has to offer, head to Table Rock State Park, Table Rock, and Table Rock State Park Headquarters and Visitor Center.
Learn more about Pickens
Pickens is well-known for its attractions such as Table Rock State Park and Table Rock.
Check out reviews of Pickens hotels guests love
Hyatt Place Greenville/Haywood
10/10 Excellent
"Great staff, very helpful, fantastic beds and breakfast."
Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
"Very clean and very friendly staff highly recommend!"
Days Inn by Wyndham Anderson
10/10 Excellent
"Jennifer was outstanding
She was very helpful and suggested a great place to eat
Room was very clean and roomy
Thanks "
Hilton Greenville
10/10 Excellent
"Awesome and super clean "
Homewood Suites by Hilton Greenville Downtown
10/10 Excellent
"Everything was great! Great location, good breakfast selection, friendly staff, clean comfortable rooms!"
Hyatt Regency Greenville
10/10 Excellent
"The hotel was beautifully decorated for Christmas, the check in staff was quick and accurate. Our room was great and we loved that we could walk to the Bon Secour Wellness Arena easily. After the event at the arena, we enjoyed a drink in the lobby."
Embassy Suites by Hilton Greenville Downtown Riverplace
10/10 Excellent
"Great Overall Experience "
Best Western Plus Greenville I-385 Inn & Suites
10/10 Excellent
"Staff"
Grand Bohemian Lodge Greenville, Autograph Collection
10/10 Excellent
"The hotel was beautiful. The room was clean. The water pressure in the shower was very low. It took quite a while for the hot water to come. The breakfast was mediocre. Coffee was cold. None of the breakfast was really hot. Location is fantastic."
Frequently asked questions
Can I book a refundable hotel in Pickens?
If you're looking for the flexibility to change your plans to Pickens, most accommodations offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Pickens if I want a vacation home instead of a hotel?
Browse 14 vacation homes on our site. You also might want to book one of 7 cottages or 18 cabins.
What will the weather in Pickens be like during my visit?
July and August are typically the warmest months in Pickens when the average temp is 76°F. January and February are the coldest months when the average temperature is 46°F. December and April are the months with the most rain.
Why should I book my Pickens hotel through Hotels.com?
There are lots of reasons to book your Pickens trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.