Poplar Bluff is a family-friendly city where you can spend time checking out the local cuisine. Take in the local culture of Poplar Bluff at Margaret Harwell Art Museum and Mo-Ark Regional Railroad Museum. A stop at other sights like Black River Coliseum and Mark Twain National Forest will create memories.
Hotels in Poplar Bluff
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Poplar Bluff?

Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff
9.2 out of 10, Wonderful, (883)
The price is $94
$106 total
includes taxes & fees
Jul 20 - Jul 21

Hampton Inn Poplar Bluff
Hampton Inn Poplar Bluff
9.4 out of 10, Exceptional, (736)
The price is $97
$109 total
includes taxes & fees
Aug 10 - Aug 11

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff
9.4 out of 10, Exceptional, (769)
The price is $99
$112 total
includes taxes & fees
Aug 3 - Aug 4

Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHG
8.8 out of 10, Excellent, (657)
The price is $87
$99 total
includes taxes & fees
Jul 27 - Jul 28

Comfort Inn Poplar Bluff North
Comfort Inn Poplar Bluff North
7.8 out of 10, Good, (368)
The price is $97
$109 total
includes taxes & fees
Aug 11 - Aug 12

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO
7.8 out of 10, Good, (1010)
The price is $79
$83 total
includes taxes & fees
Jul 14 - Jul 15

Super 8 by Wyndham Poplar Bluff Missouri
Super 8 by Wyndham Poplar Bluff Missouri
6.6 out of 10, (580)
The price is $61
$69 total
includes taxes & fees
Jul 20 - Jul 21

Lake Wappapello
Lake Wappapello
The price is $138
$146 total
includes taxes & fees
Aug 5 - Aug 6

Dexter Inn
Dexter Inn
6.8 out of 10, (305)
The price is $69
$77 total
includes taxes & fees
Jul 16 - Jul 17

OYO Hickory House Inn
OYO Hickory House Inn
5.4 out of 10, (115)
The price is $51
$64 total
includes taxes & fees
Aug 12 - Aug 13

Travelodge by Wyndham Dexter
Travelodge by Wyndham Dexter
7.4 out of 10, Good, (363)
The price is $109
$122 total
includes taxes & fees
Jul 14 - Jul 15

Econo Lodge Dexter
Econo Lodge Dexter
6.8 out of 10, (236)
The price is $59
$67 total
includes taxes & fees
Aug 11 - Aug 12

Parkview Motel
Parkview Motel
6.8 out of 10, (130)
The price is $74
$83 total
includes taxes & fees
Jul 14 - Jul 15
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Poplar Bluff
Pet friendly
Top landmarks in Poplar Bluff
Poplar Bluff Regional Medical Center
Though Poplar Bluff Regional Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Poplar Bluff while you are here.
Learn more about Poplar Bluff
Explore the historic downtown, where antique shops and local eateries line Main Street's charming brick facades. Outdoor enthusiasts can fish, kayak, or hike at nearby Lake Wappapello State Park.

Check out reviews of Poplar Bluff hotels guests love

Hampton Inn Poplar Bluff
10/10 Excellent
Frequently asked questions
Find out more about Poplar Bluff
Find out more about Poplar Bluff
Keep exploring
Keep exploring
- Landmarks
- Star Rating
- Amenities
- Hotels close to nearby airports
- Nearby cities
- Top cities in United States of America
- Most popular destinations
- More ways to book
- Hotels near Poplar Bluff Regional Medical Center
- Hotels near Black River Coliseum
- Hotels near Margaret Harwell Art Museum
- Hotels near Ozark Ridge Golf Course
- Hotels near Mo-Ark Regional Railroad Museum
- Hotels near Lake Wappapello
- Hotels near Lake Wappapello State Park
- Hotels near Hemingway Center
- Hotels near Wynn Park
- Hotels near Southeast Health Center of Stoddard County
- Hotels near The Heritage House
- Hotels near Dexter Welcome Center Depot and Museum
- Hotels near Victory Lake Golf Course
- Hotels near Corning Municipal Pool
- Hotels near Keller Veteran Memorial
- Las Vegas Hotels
- New York Hotels
- Orlando Hotels
- Myrtle Beach Hotels
- Chicago Hotels
- San Diego Hotels
- Panama City Beach Hotels
- Destin Hotels
- Los Angeles Hotels
- Ocean City Hotels
- Miami Hotels
- Boston Hotels
- Gulf Shores Hotels
- Nashville Hotels
- Atlantic City Hotels
- Pigeon Forge Hotels
- Atlanta Hotels
- San Francisco Hotels
- Houston Hotels
- Virginia Beach Hotels
Most popular destinations
Hotels
- Cheap Hotels in San Diego
- Hotels in Branson
- Hotels with Parking in Cape Girardeau
- Hotels in Boone
- Cheap Hotels in Twin Falls
- Cheap Hotels in Kirksville
- Hotels in Weston
- Hotels in Emerald Isle
- Hotels with Free Breakfast in Warrenton
- Hotels with Parking in Ironwood
- Hotels in Linn
- Hotels in Big Spring
- Family Hotels in Lebanon
- Hotels in Laconia
- Cheap Hotels in Biloxi
- Family Hotels in Colby
- Hotels in Lawrenceville
- Hotels in Neenah
- Hotels in McAllen
- Cheap Hotels in Hampton
- Hotels in Pella
- Cheap Hotels in Dothan
- Hotels in Anaheim
- Hotels in South Lake Tahoe
- Hotels in Sikeston
- Hotels with a Pool in Camdenton
- Business Hotels in Hannibal
- Hotels in Lake Ozark
- Hotels in Bolivar
- Cheap Hotels in Branson