Hotels in Mesilla

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Check prices for these dates

This weekend
May 22 - May 24
Next weekend
May 29 - May 31

Where to stay in Mesilla?

Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers

Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
3.5 star property
Las Cruces
9.2 out of 10, Wonderful, (1,771 reviews)
Experience tranquility at this Las Cruces retreat featuring an outdoor pool, 3 bars, and a nightclub. Comfortable beds await after exploring nearby Mesilla Valley Mall or watching stunning sunsets over the mountains from your historic-charm accommodations.
The price is $110
$154 total
includes taxes & fees
May 19 - May 20
Hotel Encanto de Las Cruces
Lobby

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (1,005 reviews)
Start your day with complimentary breakfast before exploring nearby vineyards. After sightseeing, unwind in the relaxing hot tub or take a dip in the indoor pool. Business travelers appreciate the free WiFi and parking, plus the attentive staff that guests consistently praise.
The price is $106
$123 total
includes taxes & fees
May 31 - Jun 1
Drury Inn & Suites Las Cruces
Exterior

Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
2.5 star property
Las Cruces
8.2 out of 10, Very Good, (1,487 reviews)
The price is $48
$57 total
includes taxes & fees
Jun 1 - Jun 2
Days Inn by Wyndham Las Cruces
Deluxe Room, 2 Double Beds, Non Smoking, Mountain View | Premium bedding, desk, iron/ironing board, free cribs/infant beds

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
3.0 star property
Las Cruces
8.2 out of 10, Very Good, (2,415 reviews)
Surrounded by breathtaking scenery, this quiet hotel offers an outdoor pool and comfortable beds near restaurants and stores. Just 15 minutes from New Mexico State University with easy freeway access, enjoy free breakfast and helpful staff.
The price is $60
$71 total
includes taxes & fees
Jun 7 - Jun 8
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Restaurant

Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,005 reviews)
This business-friendly hotel offers free breakfast, WiFi, and parking in Las Cruces. Visit nearby Luna Rossa Winery & Pizzeria or Rio Grande Vineyards, then return to clean, comfortable rooms praised by travelers for their immaculate condition.
The price is $123
$143 total
includes taxes & fees
Jun 14 - Jun 15
Hampton Inn & Suites Las Cruces I-10
Interior

Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (1,002 reviews)
Wake up refreshed at this Las Cruces haven with a 24-hour fitness center and soothing hot tub. Grab dinner at Great American Grille or unwind at the bar after exploring nearby Pan American Center and Aggie Memorial Stadium. Rooms include microwaves and refrigerators for added convenience.
The price is $124
$143 total
includes taxes & fees
May 31 - Jun 1
Hilton Garden Inn Las Cruces
Free daily buffet breakfast

Best Western Mission Inn

Best Western Mission Inn
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,221 reviews)
This serene Las Cruces hotel offers comfortable beds and a refreshing outdoor pool just minutes from campus. Enjoy the complimentary buffet breakfast before exploring nearby Luna Rossa Winery or local theaters, with free parking for added convenience.
The price is $86
$99 total
includes taxes & fees
May 20 - May 21
Best Western Mission Inn
Suite, 2 Double Beds | Down comforters, in-room safe, desk, laptop workspace

Springhill Suites By Marriott Las Cruces

Springhill Suites By Marriott Las Cruces
3.0 star property
Las Cruces
8.4 out of 10, Very Good, (1,000 reviews)
This modern hotel offers a peaceful atmosphere near Luna Rossa Winery and Rio Grande Vineyards. Start your day with free breakfast, then unwind in the outdoor pool and hot tub. Clean rooms with sofa beds welcome you back after exploring local shops.
The price is $107
$124 total
includes taxes & fees
May 31 - Jun 1
Springhill Suites By Marriott Las Cruces
Lobby

Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces
3.0 star property
Las Cruces
8.0 out of 10, Very Good, (1,003 reviews)
Soak up relaxing vibes at this peaceful hotel featuring a beautiful courtyard, indoor pool, and full-service spa. Located near American Southwest Theater Company with helpful staff ready to enhance your stay.
The price is $80
$93 total
includes taxes & fees
Jun 1 - Jun 2
Ramada Hotel & Conference Center by Wyndham Las Cruces
Restaurant

Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25
2.5 star property
Las Cruces
8.4 out of 10, Very Good, (1,001 reviews)
The price is $103
$119 total
includes taxes & fees
May 25 - May 26
Hampton Inn & Suites Las Cruces I-25
Pool

Quality Inn & Suites Las Cruces - University Area

Quality Inn & Suites Las Cruces - University Area
2.5 star property
Las Cruces
7.0 out of 10, Good, (1,001 reviews)
Wake to a complimentary continental breakfast at this peaceful Las Cruces retreat. Located near Luna Rossa Winery and Rio Grande Vineyards, this hotel offers free WiFi and parking. Guests consistently praise the helpful staff and clean, quiet rooms.
The price is $50
$59 total
includes taxes & fees
Jun 16 - Jun 17
Quality Inn & Suites Las Cruces - University Area
Lobby

Comfort Suites University Las Cruces

Comfort Suites University Las Cruces
2.5 star property
Las Cruces
8.0 out of 10, Very Good, (1,003 reviews)
Find a tranquil retreat at this golf-adjacent Las Cruces hotel featuring an indoor pool and fitness center. Located near Pan American Center and Aggie Memorial Stadium, enjoy complimentary breakfast, WiFi, and parking while experiencing the attentive service that guests consistently praise.
The price is $88
$103 total
includes taxes & fees
Jun 14 - Jun 15
Comfort Suites University Las Cruces
View from property

Courtyard by Marriott Las Cruces at NMSU

Courtyard by Marriott Las Cruces at NMSU
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (552 reviews)
Moments from New Mexico State University, this modern hotel offers a refreshing outdoor pool and 24-hour fitness center. Grab breakfast or dinner at The Bistro, unwind at the bar, and appreciate free WiFi and parking during your Las Cruces adventure.
The price is $152
$175 total
includes taxes & fees
May 24 - May 25
Courtyard by Marriott Las Cruces at NMSU
Lobby

Sleep Inn University

Sleep Inn University
2.5 star property
Las Cruces
7.6 out of 10, Good, (1,002 reviews)
This serene Las Cruces hotel offers an indoor pool, complimentary breakfast, WiFi, and parking. Guests consistently praise the quiet environment and helpful staff. Conveniently located near Pan American Center with clean, comfortable rooms.
The price is $61
$71 total
includes taxes & fees
Jun 8 - Jun 9
Sleep Inn University
Indoor pool

Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North
2.5 star property
Las Cruces
9.2 out of 10, Wonderful, (1,008 reviews)
This business-friendly hotel offers a rejuvenating indoor pool, hot tub, and spa services. Enjoy free breakfast, WiFi, and parking while exploring nearby Sonoma Ranch Golf Course. In-room refrigerators and microwaves add convenience to your southwestern stay.
The price is $112
$133 total
includes taxes & fees
Jun 14 - Jun 15
Comfort Suites Las Cruces I-25 North
Exterior

Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG
2.5 star property
Las Cruces
9.0 out of 10, Wonderful, (1,001 reviews)
Escape to Las Cruces where this hotel offers complimentary breakfast, WiFi, and parking. Relax in the indoor pool and hot tub after a workout in the fitness center. Clean rooms with microwaves and refrigerators await near Branigan Cultural Center and local attractions.
The price is $131
$151 total
includes taxes & fees
May 31 - Jun 1
Holiday Inn Express & Suites Las Cruces North by IHG
Indoor pool

Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,003 reviews)
Escape to the Mesilla area where an indoor pool and hot tub await after winery visits. Just 15 minutes from New Mexico State University, this hotel offers free breakfast, WiFi, and parking, plus in-room microwaves and refrigerators.
The price is $98
$113 total
includes taxes & fees
Jun 14 - Jun 15
Comfort Inn & Suites Las Cruces Mesilla
Exterior

Staybridge Suites Las Cruces by IHG

Staybridge Suites Las Cruces by IHG
3.0 star property
Las Cruces
8.8 out of 10, Excellent, (1,000 reviews)
Experience Las Cruces from this welcoming hotel with an outdoor pool and hot tub for relaxing after your day. Near Sonoma Ranch Golf Course and Branigan Cultural Center, the property offers free breakfast, WiFi, and convenient parking.
The price is $152
$175 total
includes taxes & fees
May 24 - May 25
Staybridge Suites Las Cruces by IHG
Exterior

La Quinta Inn by Wyndham Las Cruces Mesilla Valley

La Quinta Inn by Wyndham Las Cruces Mesilla Valley
3.0 star property
Las Cruces
5.4 out of 10, (1,008 reviews)
This welcoming Las Cruces hotel offers clean accommodations with complimentary WiFi and parking. Work out in the fitness center before exploring nearby attractions like Luna Rossa Winery & Pizzeria and Rio Grande Vineyards, just a 10-minute drive from the airport.
The price is $42
$50 total
includes taxes & fees
May 24 - May 25
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
Desk, laptop workspace, blackout drapes, soundproofing

Super 8 by Wyndham Las Cruces/White Sands Area

Super 8 by Wyndham Las Cruces/White Sands Area
2.0 star property
Las Cruces
7.2 out of 10, Good, (1,004 reviews)
Refresh in the seasonal outdoor pool at this convenient Las Cruces hotel near New Mexico State University. Enjoy free breakfast, WiFi, and parking, plus easy access to Sonoma Ranch Golf Course and Red Hawk Golf Club.
The price is $51
$60 total
includes taxes & fees
May 25 - May 26
Super 8 by Wyndham Las Cruces/White Sands Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top landmarks in Mesilla

Mesillia Plaza

4.6/5 (5 reviews)
Get a few outdoor pics when passing through Mesillia Plaza, located 0.4 mi (0.7 km) from central Mesilla.
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Learn more about Mesilla

Centuries-old adobe buildings frame the historic plaza, where the Confederate Territory of Arizona once claimed its brief capital. Duck into La Posta de Mesilla, a former stagecoach stop now serving chile rellenos that locals defend with patriotic fervor. The Fountain Theatre screens independent films in what might be the oldest movie house in the Southwest. Browse galleries where artists capture desert light in ways that make you understand why Georgia O'Keeffe never left. The Mesilla Plaza, a National Historic Landmark, hosts festivals where the smell of roasting green chiles mingles with mariachi music. Las Cruces sits just next door with its Museum of Nature & Science when you've had your fill of history.

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Red chile doorway Mesilla NM

Check out reviews of Mesilla hotels guests love

Comfort Suites University Las Cruces

Comfort Suites University Las Cruces

10/10 Excellent
"The staff was friendly and helpful. Everything was clean, but could use updating, walls, bathroom tub. Overall had a great stay with no problems."
tacv 3-night trip
Posted 2 hours ago
Comfort Suites University Las Cruces

Frequently asked questions

What hotels do travelers like in Mesilla?
Guests like Hotel Encanto de Las Cruces, Days Inn by Wyndham Las Cruces and La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain.
Can I book a refundable hotel in Mesilla?
If you want the flexibility to change your travel plans to Mesilla, most accommodations offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Mesilla if I want a vacation rental instead of a traditional hotel?
If you're looking for a good alternative to a hotel, review our selection of 8 vacation homes.
What will the weather in Mesilla be like during my trip?
The warmest months in Mesilla are usually June and July with an average temp of 82°F. January and December are the chilliest months when the average temp is 48°F. The rainiest months are August and September.
Why should I book my Mesilla accommodation with Hotels.com?
There are plenty of reasons to book your Mesilla travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.