Hotels in Mesilla

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La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
3.0 star property
Las Cruces
8.2 out of 10, Very Good, (2,357 reviews)
  • cleanliness
    Wake up to majestic mountain views at this relaxing Las Cruces retreat.
The price is $59
$70 total
includes taxes & fees
Feb 1 - Feb 2
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Days Inn by Wyndham Las Cruces
Days Inn by Wyndham Las Cruces
2.5 star property
Las Cruces
8.2 out of 10, Very Good, (1,335 reviews)
The price is $48
$57 total
includes taxes & fees
Feb 1 - Feb 2
Days Inn by Wyndham Las Cruces
Drury Inn & Suites Las Cruces
Drury Inn & Suites Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (1,008 reviews)
  • cleanliness
    Stay minutes from Luna Rossa Winery at this Las Cruces hotel with indoor pool.
The price is $94
$109 total
includes taxes & fees
Feb 1 - Feb 2
Drury Inn & Suites Las Cruces
Hampton Inn & Suites Las Cruces I-10
Hampton Inn & Suites Las Cruces I-10
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,008 reviews)
  • cleanliness
    Take a dip in the indoor pool or hit the fitness center after exploring Las Cruces.
The price is $89
$104 total
includes taxes & fees
Feb 16 - Feb 17
Hampton Inn & Suites Las Cruces I-10
Comfort Inn & Suites Las Cruces Mesilla
Comfort Inn & Suites Las Cruces Mesilla
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,004 reviews)
  • cleanliness
    Relax in this Las Cruces hotel near wineries with indoor pool and hot tub.
The price is $98
$114 total
includes taxes & fees
Jan 29 - Jan 30
Comfort Inn & Suites Las Cruces Mesilla
Best Western Mission Inn
Best Western Mission Inn
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,226 reviews)
  • cleanliness
    Quiet rooms near New Mexico State University with a helpful staff and tasty cafe.
The price is $77
$89 total
includes taxes & fees
Jan 29 - Jan 30
Best Western Mission Inn
Ramada Hotel & Conference Center by Wyndham Las Cruces
Ramada Hotel & Conference Center by Wyndham Las Cruces
3.0 star property
Las Cruces
8.0 out of 10, Very Good, (1,005 reviews)
  • cleanliness
    Tranquil Las Cruces haven with courtyard and pool near Pan American Center.
The price is $79
$92 total
includes taxes & fees
Jan 28 - Jan 29
Ramada Hotel & Conference Center by Wyndham Las Cruces
Quality Inn & Suites Las Cruces - University Area
Quality Inn & Suites Las Cruces - University Area
2.5 star property
Las Cruces
7.0 out of 10, Good, (1,002 reviews)
  • cleanliness
    Stay comfortably near New Mexico State University at this quiet, well-maintained hotel.
The price is $51
$60 total
includes taxes & fees
Feb 25 - Feb 26
Quality Inn & Suites Las Cruces - University Area
Motel 9 Las Cruces
Motel 9 Las Cruces
2.5 star property
Las Cruces
6.2 out of 10, (243 reviews)
  • cleanliness
    Affordable university lodgings with complimentary WiFi and parking nearby.
The price is $39
$46 total
includes taxes & fees
Jan 30 - Jan 31
Motel 9 Las Cruces
Springhill Suites By Marriott Las Cruces
Springhill Suites By Marriott Las Cruces
3.0 star property
Las Cruces
8.4 out of 10, Very Good, (980 reviews)
  • cleanliness
    Enjoy comfort in Las Cruces near restaurants, wine destinations, and outdoor fun.
The price is $93
$108 total
includes taxes & fees
Feb 22 - Feb 23
Springhill Suites By Marriott Las Cruces
Big Chile Inn & Suites
Big Chile Inn & Suites
2.0 star property
Las Cruces
7.0 out of 10, Good, (53 reviews)
  • cleanliness
    Close to Las Cruces museums with free WiFi and parking near New Mexico State.
The price is $72
$84 total
includes taxes & fees
Jan 28 - Jan 29
Big Chile Inn & Suites
Courtyard by Marriott Las Cruces at NMSU
Courtyard by Marriott Las Cruces at NMSU
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (519 reviews)
  • cleanliness
    Convenient campus locale with heated pool for year-round southwestern relaxation.
The price is $131
$151 total
includes taxes & fees
Feb 6 - Feb 7
Courtyard by Marriott Las Cruces at NMSU
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
3.0 star property
Las Cruces
5.4 out of 10, (1,006 reviews)
  • cleanliness
    Spacious rooms near Luna Rossa Winery with free parking and WiFi.
The price is $51
$60 total
includes taxes & fees
Feb 1 - Feb 2
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
Econo Lodge Las Cruces University Area
Econo Lodge Las Cruces University Area
2.0 star property
Las Cruces
7.2 out of 10, Good, (643 reviews)
  • cleanliness
    Steps from New Mexico State University, this hotel serves up free breakfast daily.
The price is $56
$69 total
includes taxes & fees
Feb 25 - Feb 26
Econo Lodge Las Cruces University Area
Las Cruces Home w/ Fenced Yard: Recently Remodeled
Las Cruces Home w/ Fenced Yard: Recently Remodeled
3.0 star property
Las Cruces
  • cleanliness
    Enjoy a charming cottage with a patio and kitchen in the heart of Las Cruces.
The price is $104
$263 total
includes taxes & fees
Jan 28 - Jan 29
Las Cruces Home w/ Fenced Yard: Recently Remodeled
Comfort Suites University Las Cruces
Comfort Suites University Las Cruces
2.5 star property
Las Cruces
8.0 out of 10, Very Good, (1,012 reviews)
  • cleanliness
    Peaceful golf-adjacent hotel provides serene atmosphere near Pan American Center.
The price is $80
$93 total
includes taxes & fees
Feb 5 - Feb 6
Comfort Suites University Las Cruces
Hilton Garden Inn Las Cruces
Hilton Garden Inn Las Cruces
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Peaceful Las Cruces hotel with on-site dining and fitness options near Pan American Center.
The price is $90
$105 total
includes taxes & fees
Feb 8 - Feb 9
Hilton Garden Inn Las Cruces
Super 8 by Wyndham Las Cruces University Area
Super 8 by Wyndham Las Cruces University Area
2.0 star property
Las Cruces
5.8 out of 10, (306 reviews)
  • cleanliness
    Stay near American Southwest Theater with a rejuvenating indoor pool experience.
The price is $48
$57 total
includes taxes & fees
Jan 28 - Jan 29
Super 8 by Wyndham Las Cruces University Area
Comfort Suites Las Cruces I-25 North
Comfort Suites Las Cruces I-25 North
2.5 star property
Las Cruces
9.2 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Discover Las Cruces with ease at a hotel near Mesilla Valley Mall.
The price is $97
$116 total
includes taxes & fees
Feb 22 - Feb 23
Comfort Suites Las Cruces I-25 North
Hampton Inn & Suites Las Cruces I-25
Hampton Inn & Suites Las Cruces I-25
2.5 star property
Las Cruces
8.4 out of 10, Very Good, (1,001 reviews)
The price is $89
$104 total
includes taxes & fees
Feb 22 - Feb 23
Hampton Inn & Suites Las Cruces I-25
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mesilla

Learn more about Mesilla

Centuries-old adobe buildings frame the historic plaza, where the Confederate Territory of Arizona once claimed its brief capital. Duck into La Posta de Mesilla, a former stagecoach stop now serving chile rellenos that locals defend with patriotic fervor. The Fountain Theatre screens independent films in what might be the oldest movie house in the Southwest. Browse galleries where artists capture desert light in ways that make you understand why Georgia O'Keeffe never left. The Mesilla Plaza, a National Historic Landmark, hosts festivals where the smell of roasting green chiles mingles with mariachi music. Las Cruces sits just next door with its Museum of Nature & Science when you've had your fill of history.

Red chile doorway Mesilla NM

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Frequently asked questions

What hotels do travelers like in Mesilla?
Can I book a refundable hotel in Mesilla?
If you want the flexibility to change your travel plans to Mesilla, most accommodations offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Mesilla if I want a vacation rental instead of a traditional hotel?
If you're looking for a good alternative to a hotel, review our selection of 10 vacation homes.
What will the weather in Mesilla be like during my trip?
The warmest months in Mesilla are usually June and July with an average temp of 82°F. January and December are the chilliest months when the average temp is 48°F. The rainiest months are August and September.
Why should I book my Mesilla accommodation with Hotels.com?
There are plenty of reasons to book your Mesilla travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.