Hotels in Charleston

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May 22 - May 24
Next weekend
May 29 - May 31

Where to stay in Charleston?

Lobby sitting area

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (412 reviews)
The price is $70
$78 total
includes taxes & fees
May 31 - Jun 1
The Riverstone Hotel Charleston-Sikeston
Room, 1 King Bed, Non Smoking | View from room

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
Active travelers will appreciate the health club at this comfortable Charleston motel. Free WiFi keeps you connected, while complimentary parking saves you money. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.
The price is $72
$79 total
includes taxes & fees
May 29 - May 30
Eagle Inn Charleston
Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (634 reviews)
This Charleston motel offers complimentary WiFi, parking, and on-the-go breakfast daily. Located with convenient interstate access to Cape Girardeau, guests consistently praise the helpful staff. The comfortable accommodations provide a practical base for exploring southeastern Missouri.
The price is $60
$66 total
includes taxes & fees
Jun 7 - Jun 8
Super 8 by Wyndham Charleston/Sikeston East MO
Basic Double Room | Living area

La Center Motel

La Center Motel
2.0 star property
La Center
7.6 out of 10, Good, (19 reviews)
Escape to this relaxing La Center hotel with complimentary WiFi and parking. Just a 15-minute drive from Ohio River Valley and 16 minutes from Paducah Regional Airport, the convenient location makes exploring the area effortless.
The price is $60
$70 total
includes taxes & fees
May 21 - May 22
La Center Motel
Lobby

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (285 reviews)
Set off I-57 in Cairo, this welcoming hotel provides complimentary full breakfast and self parking. Explore nearby Fort Defiance State Park or take a short drive to Ballard Wildlife Management Area while enjoying free WiFi throughout your stay.
The price is $73
$81 total
includes taxes & fees
Jun 12 - Jun 13
Quality Inn Cairo I-57
Lobby sitting area

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (574 reviews)
Overlooking the Mississippi River, this hotel puts you near Isle Casino Cape Girardeau and Riverfront Park. Enjoy 2 restaurants including Beacon 53, plus free WiFi and complimentary parking during your business-friendly stay.
The price is $132
$149 total
includes taxes & fees
May 24 - May 25
The Riverview
Lobby

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (508 reviews)
Experience Mississippi River views and explore Shawnee National Forest from this downtown Marriott. The Bistro serves American cuisine while in-room refrigerators and washers/dryers enhance comfort. Enjoy the 24-hour fitness center after visiting nearby Riverfront Park and Isle Casino.
The price is $125
$142 total
includes taxes & fees
May 29 - May 30
Courtyard by Marriott Cape Girardeau Downtown
Iron/ironing board, free WiFi, bed sheets

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (139 reviews)
This welcoming motel offers convenience with complimentary WiFi and parking, plus round-the-clock front desk assistance. Explore nearby Central Park and Sikeston Depot Museum before returning to your comfortable accommodations.
The price is $57
$68 total
includes taxes & fees
May 21 - May 22
Country Yard Inn and Suite
1 bedroom, desk, laptop workspace, blackout drapes

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.4 out of 10, Good, (1,003 reviews)
Travelers rave about this serene retreat with helpful staff and clean rooms. Take advantage of free WiFi, parking, and on-the-go breakfast. Work out in the fitness center before exploring Central Park and Sikeston Depot Museum nearby.
The price is $68
$78 total
includes taxes & fees
Jun 7 - Jun 8
Days Inn and Suites by Wyndham Sikeston
Free daily full breakfast

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,012 reviews)
Experience comfort at this Sikeston hotel, offering free breakfast and parking close to Central Park. The helpful staff welcomes guests to enjoy the indoor pool and fitness center. With easy access to Sikeston Depot Museum, you'll find everything needed for a convenient Missouri stay.
The price is $90
$103 total
includes taxes & fees
Jun 7 - Jun 8
Best Western Plus Sikeston I-55
Lobby

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (20 reviews)
Wake up refreshed at this cozy Cape Girardeau retreat with free WiFi and parking. Explore nearby attractions like Show Me Center and Isle Casino, then unwind in the tranquil garden after your adventures.
The price is $150
$170 total
includes taxes & fees
May 21 - May 22
Rockwood Inn
Indoor pool, outdoor pool

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,003 reviews)
Escape to this serene Sikeston hotel with both indoor and outdoor pools near restaurants and shopping. The fitness center, free breakfast, WiFi and parking enhance your stay, while the helpful staff ensures comfort just minutes from Central Park.
The price is $111
$128 total
includes taxes & fees
May 25 - May 26
Drury Inn & Suites Sikeston, MO
Individually decorated, individually furnished, desk, blackout drapes

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (780 reviews)
This peaceful hotel offers a complimentary continental breakfast, free WiFi, and convenient parking. Located near I-55 Exit 67, guests consistently praise the helpful staff and clean rooms that provide a quiet retreat after exploring local attractions.
The price is $67
$77 total
includes taxes & fees
May 21 - May 22
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Exterior

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (293 reviews)
Warm comfort awaits at this Sikeston hotel where the indoor pool invites morning swims. Just minutes from Central Park and Sikeston Depot Museum, enjoy free WiFi, parking, and a fitness center while helpful staff enhance your stay.
The price is $94
$107 total
includes taxes & fees
Jun 14 - Jun 15
Comfort Inn & Suites Sikeston I-55
Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout drapes, free WiFi

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (627 reviews)
Cozy lodging near Central Park and Sikeston Depot Museum with complimentary breakfast, WiFi, and parking. Just 29 minutes from Cape Girardeau Municipal Airport, this Super 8 offers comfortable accommodations for exploring the area.
The price is $63
$72 total
includes taxes & fees
May 21 - May 22
Super 8 by Wyndham Sikeston/Miner Area
Desk, free WiFi

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, (224 reviews)
Wake up to adventure at this Cape Girardeau motel near the Family Aquatic Center and Show Me Center. Enjoy hassle-free travel with free WiFi, complimentary parking, and 24-hour front desk service for your Missouri getaway.
The price is $75
$88 total
includes taxes & fees
May 21 - May 22
Town House Inn Cape Giradreau
Exterior

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very Good, (937 reviews)
The price is $74
$89 total
includes taxes & fees
May 25 - May 26
Candlewood Suites Cape Girardeau by IHG
Lobby

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (185 reviews)
Discover Cape Girardeau from this hotel with free WiFi, parking, and continental breakfast. Take a refreshing dip in the indoor pool after exploring nearby attractions like Fort D Historic Site and Cape Splash Family Aquatic Center.
The price is $93
$105 total
includes taxes & fees
May 28 - May 29
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (815 reviews)
Wake up to a free breakfast at this Cape Girardeau hotel, just minutes from Shawnee National Forest and the Mississippi River. Swim in the indoor pool, work out in the fitness center, or relax on the terrace after exploring nearby aquatic attractions.
The price is $106
$119 total
includes taxes & fees
May 25 - May 26
Hampton Inn Cape Girardeau I 55 East
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
Discover Cape Girardeau from this central hotel with easy access to restaurants and shopping. Enjoy the indoor pool and fitness center, then wake up to a free breakfast. Helpful staff ensure a smooth stay with convenient free WiFi and parking.
The price is $110
$124 total
includes taxes & fees
May 24 - May 25
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Charleston?

Our prices for hotels in Charleston are cheapest in January
Price trends for hotels in Charleston
Pricing is based on two traveler single night rates
View properties in May
Currently viewing crowd sizes and weather for May.
Typical weather for Charleston
May
High 25°C / low 15°C. Sunny most days.
View properties in May
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May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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July, no crowd data, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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December, no crowd data, average high temperature 9 degrees Celsius, average low temperature 2 degrees Celsius. Partly sunny.
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January, no crowd data, average high temperature 6 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
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February, no crowd data, average high temperature 8 degrees Celsius, average low temperature 0 degrees Celsius. Partly sunny.
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March, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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April, no crowd data, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Learn more about Charleston

Charleston is well-known for its attractions such as Mississippi River and Ohio River. Visitors give high marks to the city's restaurants and small-town setting.

See all hotels in Charleston
Cypress Trees on the Horizon. A sting of cypress trees of various sizes extend across the horizon as the sunken sun paints the multicolored sky.

Check out reviews of Charleston hotels guests love

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

8/10 Good
"First time staying here and was completely pleased with what it offered. The hot breakfast and hot dinner was very nice they offered each night and the three drinks per night also. We will be back again. "
Susan 2-night trip
Posted 5 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center

Frequently asked questions

What hotels do travelers recommend in Charleston?
Guests like Super 8 by Wyndham Charleston/Sikeston East MO, The Riverstone Hotel Charleston-Sikeston and Eagle Inn Charleston.
Can I book a refundable accommodation in Charleston?
If you're looking for the flexibility to change your plans to Charleston, most accommodations offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where should I consider staying in Charleston if I'm looking for a cheap accommodation?
An inexpensive option worth considering is The Riverstone Hotel Charleston-Sikeston.
What will the weather in Charleston be like during my vacation?
July and August are typically the warmest months in Charleston when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. April and March are the months with the most rain.
Why should I book my Charleston accommodation with Hotels.com?
There are lots of reasons to book your Charleston trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.