Hotels in Charleston

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Where to stay in Charleston?

The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (408 reviews)
The price is $70
$78 total
includes taxes & fees
Mar 3 - Mar 4
The Riverstone Hotel Charleston-Sikeston
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (625 reviews)
This Charleston motel offers complimentary WiFi, parking, and on-the-go breakfast daily. Located with convenient interstate access to Cape Girardeau, guests consistently praise the helpful staff. The comfortable accommodations provide a practical base for exploring southeastern Missouri.
The price is $62
$69 total
includes taxes & fees
Mar 3 - Mar 4
Super 8 by Wyndham Charleston/Sikeston East MO
Eagle Inn Charleston
Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105 reviews)
Active travelers will appreciate the health club at this comfortable Charleston motel. Free WiFi keeps you connected, while complimentary parking saves you money. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.
The price is $64
$71 total
includes taxes & fees
Mar 3 - Mar 4
Eagle Inn Charleston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,007 reviews)
Escape to this serene Sikeston hotel with both indoor and outdoor pools near restaurants and shopping. The fitness center, free breakfast, WiFi and parking enhance your stay, while the helpful staff ensures comfort just minutes from Central Park.
The price is $94
$108 total
includes taxes & fees
Mar 8 - Mar 9
Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,003 reviews)
Travelers rave about this serene retreat with helpful staff and clean rooms. Take advantage of free WiFi, parking, and on-the-go breakfast. Work out in the fitness center before exploring Central Park and Sikeston Depot Museum nearby.
The price is $71
$80 total
includes taxes & fees
Mar 4 - Mar 5
Days Inn and Suites by Wyndham Sikeston
Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (598 reviews)
Cozy lodging near Central Park and Sikeston Depot Museum with complimentary breakfast, WiFi, and parking. Just 29 minutes from Cape Girardeau Municipal Airport, this Super 8 offers comfortable accommodations for exploring the area.
The price is $61
$70 total
includes taxes & fees
Mar 8 - Mar 9
Super 8 by Wyndham Sikeston/Miner Area
Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,004 reviews)
Experience comfort at this Sikeston hotel, offering free breakfast and parking close to Central Park. The helpful staff welcomes guests to enjoy the indoor pool and fitness center. With easy access to Sikeston Depot Museum, you'll find everything needed for a convenient Missouri stay.
The price is $82
$93 total
includes taxes & fees
Mar 26 - Mar 27
Best Western Plus Sikeston I-55
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (747 reviews)
This peaceful hotel offers a complimentary continental breakfast, free WiFi, and convenient parking. Located near I-55 Exit 67, guests consistently praise the helpful staff and clean rooms that provide a quiet retreat after exploring local attractions.
The price is $65
$75 total
includes taxes & fees
Mar 3 - Mar 4
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (287 reviews)
Warm comfort awaits at this Sikeston hotel where the indoor pool invites morning swims. Just minutes from Central Park and Sikeston Depot Museum, enjoy free WiFi, parking, and a fitness center while helpful staff enhance your stay.
The price is $93
$107 total
includes taxes & fees
Mar 15 - Mar 16
Comfort Inn & Suites Sikeston I-55
Country Yard Inn and Suite
Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (124 reviews)
This welcoming motel offers convenience with complimentary WiFi and parking, plus round-the-clock front desk assistance. Explore nearby Central Park and Sikeston Depot Museum before returning to your comfortable accommodations.
The price is $53
$64 total
includes taxes & fees
Mar 3 - Mar 4
Country Yard Inn and Suite
Quality Inn Cairo I-57
Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (282 reviews)
Set off I-57 in Cairo, this welcoming hotel provides complimentary full breakfast and self parking. Explore nearby Fort Defiance State Park or take a short drive to Ballard Wildlife Management Area while enjoying free WiFi throughout your stay.
The price is $68
$76 total
includes taxes & fees
Mar 20 - Mar 21
Quality Inn Cairo I-57
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (448 reviews)
Experience Sikeston from this hotel with free breakfast, WiFi, and parking. Take a morning dip in the indoor pool or hit the fitness center. Near Central Park and Sikeston Depot Museum, guests love the helpful staff and clean rooms.
The price is $93
$105 total
includes taxes & fees
Mar 22 - Mar 23
Holiday Inn Express & Suites Sikeston Southwest by IHG
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (60 reviews)
Located in Sikeston, this hotel offers free breakfast, WiFi, and parking. Take a refreshing swim in the indoor pool or grab a bite at the restaurant. Nearby attractions include Central Park and Sikeston Depot Museum for local exploration.
The price is $101
$114 total
includes taxes & fees
Mar 12 - Mar 13
Fairfield Inn & Suites by Marriott Sikeston
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (493 reviews)
Dive into vacation mode at this welcoming hotel with an indoor pool and fitness center near Central Park. After enjoying the complimentary breakfast, explore Sikeston Depot Museum before returning to relax in modern rooms with free WiFi.
The price is $95
$108 total
includes taxes & fees
Mar 29 - Mar 30
Hampton Inn Sikeston
TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (12 reviews)
The price is $114
$129 total
includes taxes & fees
Mar 8 - Mar 9
TownePlace Suites by Marriott Sikeston
La Center Motel
La Center Motel
2.0 star property
La Center
7.8 out of 10, Good, (17 reviews)
Escape to this relaxing La Center hotel with complimentary WiFi and parking. Just a 15-minute drive from Ohio River Valley and 16 minutes from Paducah Regional Airport, the convenient location makes exploring the area effortless.
The price is $60
$70 total
includes taxes & fees
Mar 3 - Mar 4
La Center Motel
Quiet Country Stay: Modern Home Near Paducah
Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is $121
$290 total
includes taxes & fees
Mar 9 - Mar 10
Quiet Country Stay: Modern Home Near Paducah
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (899 reviews)
The price is $80
$96 total
includes taxes & fees
Mar 4 - Mar 5
Candlewood Suites Cape Girardeau by IHG
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (490 reviews)
Experience Mississippi River views and explore Shawnee National Forest from this downtown Marriott. The Bistro serves American cuisine while in-room refrigerators and washers/dryers enhance comfort. Enjoy the 24-hour fitness center after visiting nearby Riverfront Park and Isle Casino.
The price is $121
$137 total
includes taxes & fees
Mar 15 - Mar 16
Courtyard by Marriott Cape Girardeau Downtown
The Riverview
The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (516 reviews)
Overlooking the Mississippi River, this hotel puts you near Isle Casino Cape Girardeau and Riverfront Park. Enjoy 2 restaurants including Beacon 53, plus free WiFi and complimentary parking during your business-friendly stay.
The price is $96
$109 total
includes taxes & fees
Mar 9 - Mar 10
The Riverview
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit Charleston?

Our prices for hotels in Charleston are cheapest in November
Price trends for hotels in Charleston
Pricing is based on two traveler single night rates
View properties in March
Currently viewing crowd sizes and weather for March.
Typical weather for Charleston
March
High 14°C / low 5°C. Partly sunny.
View properties in March
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March, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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April, no crowd data, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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July, no crowd data, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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December, no crowd data, average high temperature 9 degrees Celsius, average low temperature 2 degrees Celsius. Partly sunny.
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January, no crowd data, average high temperature 6 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
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February, no crowd data, average high temperature 8 degrees Celsius, average low temperature 0 degrees Celsius. Partly sunny.
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Learn more about Charleston

Charleston is well-known for its attractions such as Mississippi River and Ohio River. Visitors give high marks to the city's restaurants and small-town setting.

Cypress Trees on the Horizon.  A sting of cypress trees of various sizes extend across the horizon as the sunken sun paints the multicolored sky.

Check out reviews of Charleston hotels guests love

Frequently asked questions

What hotels do travelers recommend in Charleston?
Super 8 by Wyndham Charleston/Sikeston East MO and Eagle Inn Charleston are a couple of properties that our guests really like.
Can I book a refundable accommodation in Charleston?
If you're looking for the flexibility to change your plans to Charleston, most accommodations offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Charleston be like during my vacation?
July and August are typically the warmest months in Charleston when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. April and March are the months with the most rain.
Why should I book my Charleston accommodation with Hotels.com?
There are lots of reasons to book your Charleston trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.