Hotels logo

Hotels in Opelousas

October 2026
5
November 2026

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Where to stay in Opelousas?

A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.
A snack display with various chips and snacks.
A poolside area with lounge chairs, a glass table, and a brick building in the background.
A spacious kitchen area with wooden cabinets, a central island, and various appliances.

1. Hampton Inn Opelousas

Hampton Inn Opelousas
Opelousas
$110
$129 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn Opelousas
A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.
A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".
A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.
A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

2. Holiday Inn Express & Suites Opelousas by IHG

Holiday Inn Express & Suites Opelousas by IHG
Opelousas
$129
$152 total
includes taxes & fees
Nov 4 - Nov 5
Holiday Inn Express & Suites Opelousas by IHG
A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.
A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.
A reception desk with a stone facade, blue walls, and a chandelier.
A hotel room with two beds, a sofa, a chair, and a wooden table.

3. Days Inn & Suites by Wyndham Opelousas

Days Inn & Suites by Wyndham Opelousas
Opelousas
$68
$80 total
includes taxes & fees
Nov 1 - Nov 2
Days Inn & Suites by Wyndham Opelousas
A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.
A shower enclosure with a glass door, a showerhead, and a handheld shower attachment.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

4. Spark by Hilton Opelousas

Spark by Hilton Opelousas
Opelousas
$93
$109 total
includes taxes & fees
Oct 11 - Oct 12
Spark by Hilton Opelousas
A gas station with a covered parking area, a building with multiple windows, and a sign indicating it's now open.
A hotel room with a bed, a flat-screen TV mounted on the wall, a refrigerator, a small wooden side table, and a mirror.
A reception desk with a number '6' sign above it, a fire extinguisher, and a blue informational poster on the wall.
A bathroom with a granite countertop, a sink, a mirror, a towel rack, and a heater.

5. Studio 6 Suites Opelousas, LA

Studio 6 Suites Opelousas, LA
Opelousas
$58
$73 total
includes taxes & fees
Oct 6 - Oct 7
Studio 6 Suites Opelousas, LA
A reception area with a large number '6' on the wall, a flat-screen TV mounted on the wall, and two reception desks.
A hotel room with a dining area, a flat-screen TV mounted on the wall, and two posters advertising travel savings.
A hotel courtyard with a central swimming pool, multiple balconies, and palm trees.
A blue building with a covered entrance and palm trees in the foreground.

6. Motel 6 Opelousas, LA

Motel 6 Opelousas, LA
Opelousas
$53
$63 total
includes taxes & fees
Oct 26 - Oct 27
Motel 6 Opelousas, LA
A reception desk with a blue geometric wall design and a wooden accent.
A hotel room with two beds, a desk, a chair, and a wardrobe.
A kitchenette with two black refrigerators stocked with beverages and snacks, a wooden cabinet with various food items, and a shelf with packaged goods.
A modern breakfast area with a counter displaying various food items and a refrigerated display case.

7. Holiday Inn Express Breaux Bridge by IHG

Holiday Inn Express Breaux Bridge by IHG
Breaux Bridge
$93
$109 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express Breaux Bridge by IHG
A hotel room with a large bed, a desk with a chair, a chair, and a lamp.
A row of sun loungers with a pair of rolled towels placed on one.
A swimming pool with a geometric tile design, surrounded by palm trees and a fence.
A two-story building with a balcony and a covered porch.

8. Hotel Klaus

Hotel Klaus
Washington
$115
$170 total
includes taxes & fees
Oct 6 - Oct 7
Hotel Klaus
A spacious lobby with a reception desk, seating area, and a large potted plant.
A hotel with a swimming pool, lounge chairs, and a covered patio area.
A hotel room with two beds, a large mirror, a flat-screen TV, and a window with curtains.
A conference room with a long table, four bar stools, a television, and framed pictures on the wall.

9. Motel 6 Breaux Bridge, La

Motel 6 Breaux Bridge, La
Breaux Bridge
$52
$65 total
includes taxes & fees
Oct 6 - Oct 7
Motel 6 Breaux Bridge, La
A modern lobby with grey upholstered armchairs, a round wooden ottoman, and a patterned rug.
A spacious indoor dining area with multiple tables and chairs, large windows, and a polished floor.
A hotel room with a sofa, a small table, a TV, a desk with a chair, and a wardrobe.
A hotel room with two beds, a desk, a television, and a wardrobe.

10. Drury Inn & Suites Lafayette, LA

Drury Inn & Suites Lafayette, LA
Lafayette
$117
$138 total
includes taxes & fees
Oct 11 - Oct 12
Drury Inn & Suites Lafayette, LA
A lobby with two yellow sofas, a coffee table, and a reception desk.
A hotel room with a flat-screen TV, a desk with a computer, a sofa, and a coffee table. There is a window with curtains, a wall-mounted lamp, and a small painting.
A kitchen with blue cabinets, a coffee machine, a toaster, and a grill.
A modern hotel room with a large bed, a nightstand, a desk, and a window with curtains.

11. Comfort Inn Lafayette North I-10

Comfort Inn Lafayette North I-10
Lafayette
$69
$79 total
includes taxes & fees
Oct 24 - Oct 25
Comfort Inn Lafayette North I-10
A spacious lobby with a modern design, featuring a seating area, a fireplace, and a refreshment bar.
A spacious living room with a large sofa, ottomans, and a fireplace.
A Hilton Garden Inn hotel with a covered entrance and a large parking lot.
A spacious lobby with a fireplace, seating area, and a reception desk.

12. Hilton Garden Inn Lafayette/Cajundome

Hilton Garden Inn Lafayette/Cajundome
Lafayette
$94
$111 total
includes taxes & fees
Oct 12 - Oct 13
Hilton Garden Inn Lafayette/Cajundome
A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase to an upper level.
A spacious lobby with a high ceiling, a central seating area with sofas, a coffee table, and a staircase leading to an upper level.
A hotel room with two beds, a wooden headboard, a nightstand with a clock, and a carpeted floor.
A living room with a blue sofa, a small coffee table, and a TV on a wooden stand.

13. Wingate by Wyndham Lafayette Airport

Wingate by Wyndham Lafayette Airport
Lafayette
$76
$87 total
includes taxes & fees
Oct 12 - Oct 13
Wingate by Wyndham Lafayette Airport
A hotel entrance with a covered driveway, palm trees, and a sign for Homewood Suites.
A covered patio area with outdoor seating and a stone wall.
A lobby with a seating area, a reception desk, and a view of the outside.
A spacious hotel lobby with high ceilings, a central seating area, and a bar.

14. Homewood Suites by Hilton Lafayette, LA

Homewood Suites by Hilton Lafayette, LA
Lafayette
$93
$108 total
includes taxes & fees
Oct 30 - Oct 31
Homewood Suites by Hilton Lafayette, LA
A modern outdoor seating area with fire pit, chairs, and a covered patio.
A modern hotel reception area with a counter, coffee machines, and a fruit display.
A modern building with a sign reading 'HOME 2' and a water feature with fountains.
A modern hotel reception desk with a wooden finish, two monitors, and a sign that reads 'HOME2'.

15. Home2 Suites By Hilton Lafayette I-10

Home2 Suites By Hilton Lafayette I-10
Lafayette
$115
$132 total
includes taxes & fees
Oct 19 - Oct 20
Home2 Suites By Hilton Lafayette I-10
A house with a blue front door, white columns, and a brick porch.
A laundry room with a washing machine, dryer, and a window with a view.
A spacious living room with a fireplace, leather sofas, a chandelier, and various artworks.
A brick pathway leading to a building with a tiled roof, surrounded by lush greenery and flowering plants.

16. 476 Nona st Breaux Bridge LA US 70517

476 Nona st Breaux Bridge LA US 70517
Breaux Bridge
$63
$72 total
includes taxes & fees
Oct 6 - Oct 7
476 Nona st Breaux Bridge LA US 70517
A hotel laundry area with Whirlpool washers and dryers, a sign with guest laundry guidelines, and a Whirlpool self-service machine.
A hotel room with two beds, a flat-screen TV, a coffee maker, and a small refrigerator.
A reception desk with a wooden finish, a large wall-mounted crescent moon decoration, and several framed certificates on the wall.
A Comfort Inn & Suites hotel with a covered entrance and a landscaped driveway.

17. Comfort Inn & Suites Scott-West Lafayette

Comfort Inn & Suites Scott-West Lafayette
Scott
$84
$102 total
includes taxes & fees
Oct 31 - Nov 1
Comfort Inn & Suites Scott-West Lafayette
A modern hotel room with a large bed, a TV, a desk, and a carpeted floor.
A hotel room with a flat-screen TV mounted above a wooden cabinet, a microwave, and a small bedside table with a lamp.
A gym with treadmills, an elliptical, a bench, and a dumbbell rack.
A hotel room with a green sofa, wooden tables, and chairs.

18. City Express By Marriott Lafayette

City Express By Marriott Lafayette
Lafayette
$78
$90 total
includes taxes & fees
Oct 11 - Oct 12
City Express By Marriott Lafayette
A hotel room with a large bed, a nightstand with a lamp, and a zebra-patterned carpet.
A vending machine with various drink options, a metal cart, and a window with blinds.
A small bathroom with a sink, toilet, and hand dryer.
A hotel room with two beds, a nightstand with a lamp, a striped sofa, and a patterned carpet.

19. Executive Inn & Suites Breaux Bridge, LA

Executive Inn & Suites Breaux Bridge, LA
Breaux Bridge
$48
$58 total
includes taxes & fees
Oct 6 - Oct 7
Executive Inn & Suites Breaux Bridge, LA
View all properties

Get last-minute hotel deals in Opelousas and save more

Sign in to unlock great savings.
A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.
A snack display with various chips and snacks.
A poolside area with lounge chairs, a glass table, and a brick building in the background.
A spacious kitchen area with wooden cabinets, a central island, and various appliances.

Hampton Inn Opelousas

Hampton Inn Opelousas
Opelousas
$129
per night
$152 total
includes taxes & fees
Hampton Inn Opelousas
A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.
A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.
A reception desk with a stone facade, blue walls, and a chandelier.
A hotel room with two beds, a sofa, a chair, and a wooden table.

Days Inn & Suites by Wyndham Opelousas

Days Inn & Suites by Wyndham Opelousas
Opelousas
$9 off
$78
per night
$92 total
includes taxes & fees
Days Inn & Suites by Wyndham Opelousas
A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.
A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".
A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.
A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

Holiday Inn Express & Suites Opelousas by IHG

Holiday Inn Express & Suites Opelousas by IHG
Opelousas
$154
per night
$181 total
includes taxes & fees
Holiday Inn Express & Suites Opelousas by IHG
A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.
A shower enclosure with a glass door, a showerhead, and a handheld shower attachment.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

Spark by Hilton Opelousas

Spark by Hilton Opelousas
Opelousas
$109
per night
$128 total
includes taxes & fees
Spark by Hilton Opelousas
A gas station with a covered parking area, a building with multiple windows, and a sign indicating it's now open.
A hotel room with a bed, a flat-screen TV mounted on the wall, a refrigerator, a small wooden side table, and a mirror.
A reception desk with a number '6' sign above it, a fire extinguisher, and a blue informational poster on the wall.
A bathroom with a granite countertop, a sink, a mirror, a towel rack, and a heater.

Studio 6 Suites Opelousas, LA

Studio 6 Suites Opelousas, LA
Opelousas
$7 off
$58
per night
$73 total
includes taxes & fees
Studio 6 Suites Opelousas, LA
A reception area with a large number '6' on the wall, a flat-screen TV mounted on the wall, and two reception desks.
A hotel room with a dining area, a flat-screen TV mounted on the wall, and two posters advertising travel savings.
A hotel courtyard with a central swimming pool, multiple balconies, and palm trees.
A blue building with a covered entrance and palm trees in the foreground.

Motel 6 Opelousas, LA

Motel 6 Opelousas, LA
Opelousas
$64
per night
$75 total
includes taxes & fees
Motel 6 Opelousas, LA
A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.
A snack display with various chips and snacks.
A poolside area with lounge chairs, a glass table, and a brick building in the background.
A spacious kitchen area with wooden cabinets, a central island, and various appliances.

Hampton Inn Opelousas

Hampton Inn Opelousas
Opelousas
$129
per night
$152 total
includes taxes & fees
Hampton Inn Opelousas
A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.
A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.
A reception desk with a stone facade, blue walls, and a chandelier.
A hotel room with two beds, a sofa, a chair, and a wooden table.

Days Inn & Suites by Wyndham Opelousas

Days Inn & Suites by Wyndham Opelousas
Opelousas
$9 off
$78
per night
$92 total
includes taxes & fees
Days Inn & Suites by Wyndham Opelousas
A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.
A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".
A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.
A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

Holiday Inn Express & Suites Opelousas by IHG

Holiday Inn Express & Suites Opelousas by IHG
Opelousas
$164
per night
$193 total
includes taxes & fees
Holiday Inn Express & Suites Opelousas by IHG
A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.
A shower enclosure with a glass door, a showerhead, and a handheld shower attachment.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

Spark by Hilton Opelousas

Spark by Hilton Opelousas
Opelousas
$119
per night
$140 total
includes taxes & fees
Spark by Hilton Opelousas
A gas station with a covered parking area, a building with multiple windows, and a sign indicating it's now open.
A hotel room with a bed, a flat-screen TV mounted on the wall, a refrigerator, a small wooden side table, and a mirror.
A reception desk with a number '6' sign above it, a fire extinguisher, and a blue informational poster on the wall.
A bathroom with a granite countertop, a sink, a mirror, a towel rack, and a heater.

Studio 6 Suites Opelousas, LA

Studio 6 Suites Opelousas, LA
Opelousas
$7 off
$58
per night
$73 total
includes taxes & fees
Studio 6 Suites Opelousas, LA
A reception area with a large number '6' on the wall, a flat-screen TV mounted on the wall, and two reception desks.
A hotel room with a dining area, a flat-screen TV mounted on the wall, and two posters advertising travel savings.
A hotel courtyard with a central swimming pool, multiple balconies, and palm trees.
A blue building with a covered entrance and palm trees in the foreground.

Motel 6 Opelousas, LA

Motel 6 Opelousas, LA
Opelousas
$63
per night
$74 total
includes taxes & fees
Motel 6 Opelousas, LA
A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.
A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.
A reception desk with a stone facade, blue walls, and a chandelier.
A hotel room with two beds, a sofa, a chair, and a wooden table.

Days Inn & Suites by Wyndham Opelousas

Days Inn & Suites by Wyndham Opelousas
Opelousas
$33 off
$93
per night
$218 total
includes taxes & fees
Days Inn & Suites by Wyndham Opelousas
A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.
A snack display with various chips and snacks.
A poolside area with lounge chairs, a glass table, and a brick building in the background.
A spacious kitchen area with wooden cabinets, a central island, and various appliances.

Hampton Inn Opelousas

Hampton Inn Opelousas
Opelousas
$184
per night
$434 total
includes taxes & fees
Hampton Inn Opelousas
A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.
A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".
A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.
A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

Holiday Inn Express & Suites Opelousas by IHG

Holiday Inn Express & Suites Opelousas by IHG
Opelousas
$193
per night
$455 total
includes taxes & fees
Holiday Inn Express & Suites Opelousas by IHG
A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.
A shower enclosure with a glass door, a showerhead, and a handheld shower attachment.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

Spark by Hilton Opelousas

Spark by Hilton Opelousas
Opelousas
$131
per night
$309 total
includes taxes & fees
Spark by Hilton Opelousas
A reception area with a large number '6' on the wall, a flat-screen TV mounted on the wall, and two reception desks.
A hotel room with a dining area, a flat-screen TV mounted on the wall, and two posters advertising travel savings.
A hotel courtyard with a central swimming pool, multiple balconies, and palm trees.
A blue building with a covered entrance and palm trees in the foreground.

Motel 6 Opelousas, LA

Motel 6 Opelousas, LA
Opelousas
$63
per night
$148 total
includes taxes & fees
Motel 6 Opelousas, LA

Check out pet-friendly hotels in Opelousas

A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.
A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".
A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.
A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

Holiday Inn Express & Suites Opelousas by IHG

Holiday Inn Express & Suites Opelousas by IHG
Opelousas
$129
$152 total
includes taxes & fees
Nov 4 - Nov 5
Holiday Inn Express & Suites Opelousas by IHG
A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.
A snack display with various chips and snacks.
A poolside area with lounge chairs, a glass table, and a brick building in the background.
A spacious kitchen area with wooden cabinets, a central island, and various appliances.

Hampton Inn Opelousas

Hampton Inn Opelousas
Opelousas
$110
$129 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn Opelousas
A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.
A shower enclosure with a glass door, a showerhead, and a handheld shower attachment.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

Spark by Hilton Opelousas

Spark by Hilton Opelousas
Opelousas
$93
$109 total
includes taxes & fees
Oct 11 - Oct 12
Spark by Hilton Opelousas
A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.
A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.
A reception desk with a stone facade, blue walls, and a chandelier.
A hotel room with two beds, a sofa, a chair, and a wooden table.

Days Inn & Suites by Wyndham Opelousas

Days Inn & Suites by Wyndham Opelousas
Opelousas
$68
$80 total
includes taxes & fees
Nov 1 - Nov 2
Days Inn & Suites by Wyndham Opelousas
A gas station with a covered parking area, a building with multiple windows, and a sign indicating it's now open.
A hotel room with a bed, a flat-screen TV mounted on the wall, a refrigerator, a small wooden side table, and a mirror.
A reception desk with a number '6' sign above it, a fire extinguisher, and a blue informational poster on the wall.
A bathroom with a granite countertop, a sink, a mirror, a towel rack, and a heater.

Studio 6 Suites Opelousas, LA

Studio 6 Suites Opelousas, LA
Opelousas
$58
$73 total
includes taxes & fees
Oct 6 - Oct 7
Studio 6 Suites Opelousas, LA
A reception area with a large number '6' on the wall, a flat-screen TV mounted on the wall, and two reception desks.
A hotel room with a dining area, a flat-screen TV mounted on the wall, and two posters advertising travel savings.
A hotel courtyard with a central swimming pool, multiple balconies, and palm trees.
A blue building with a covered entrance and palm trees in the foreground.

Motel 6 Opelousas, LA

Motel 6 Opelousas, LA
Opelousas
$53
$63 total
includes taxes & fees
Oct 26 - Oct 27
Motel 6 Opelousas, LA
View all properties

Go beyond your typical stay in Opelousas

pet friendly image
Pet friendly
Pet friendly
Pool image
Pool
Pool
hot tub image
Hot tub
Hot tub
Family friendly image
Family friendly
Family friendly
spa image
Spa
Spa
Apartment image
Apart­ment
Apart­ment
Cottage image
Cottage
Cottage
Condo image
Condo
Condo
Our prices for hotels in Opelousas are cheapest in December

Price trends for hotels in Opelousas

Pricing is based on two traveler single night rates
View properties in October

October

High 27°C / low 16°C. Sunny most days.
27°
16°
20°
11°
17°
8°
15°
6°
17°
8°
21°
12°
25°
15°
29°
19°
32°
22°
32°
23°
32°
23°
31°
21°
Monthly weather averages (˚C)

Top landmarks in Opelousas

Evangeline Downs Racetrack & Casino

Evangeline Downs Racetrack & Casino is 1.4 mi (2.2 km) from central Opelousas, why not stop by during your stay.
See properties

St. Landry Catholic Church

8.2/10 (26 reviews)
St. Landry Catholic Church is 0.7 mi (1.1 km) from central Opelousas, why not stop by during your stay.
See properties

Louisiana Orphan Train Museum

8.0/10 (17 reviews)
If museums are on your list of things to see in Opelousas, then you might want to head to Louisiana Orphan Train Museum. If you want to see more of the museums in Opelousas, you can easily walk to Fireman's Museum.
See properties

Opelousas Historic District

If you're planning a bit of sightseeing during your trip, head to Opelousas Historic District— just one of the monuments in central Opelousas.
See properties

Opelousas Museum And Interpretive Center

The center of Opelousas is home to cultural attractions like Opelousas Museum And Interpretive Center, so you might want to stop by during your stay. If you want to experience more of the culture Opelousas has to offer, head to St. Landry Catholic Church, Louisiana Orphan Train Museum, and Evangeline Downs Racetrack & Casino.
See properties

Fireman's Museum

If museums are on your list of things to see, then you might want to head to Fireman's Museum, located in the heart of Opelousas.If you want to see more of the museums in Opelousas, you can easily walk to Louisiana Orphan Train Museum or Opelousas Museum And Interpretive Center.
See properties

Opelousas Public Library

Opelousas Public Library is worth a visit when in central Opelousas.
See properties

North Park

North Park is worth a visit, located 1.2 mi (1.9 km) from central Opelousas.
See properties

Learn more about Opelousas

Savor spicy Cajun cuisine at local eateries like Palace Cafe, then tap your toes to zydeco music. Explore the Opelousas Museum and Interpretive Center to uncover the city's rich history as 'The Spice Capital of the World.'

See all hotels in Opelousas
A sunset over a calm lake with Spanish moss-covered trees.

Check out reviews of Opelousas hotels guests love

A modern lobby with grey upholstered armchairs, a round wooden ottoman, and a patterned rug.
A spacious indoor dining area with multiple tables and chairs, large windows, and a polished floor.
A hotel room with a sofa, a small table, a TV, a desk with a chair, and a wardrobe.
A hotel room with two beds, a desk, a television, and a wardrobe.

Drury Inn & Suites Lafayette, LA

Drury Inn & Suites Lafayette, LA
Lafayette

10/10 Exceptional

United States
salvatore
Drury Inn & Suites Lafayette, LA
A hotel entrance with a covered driveway, palm trees, and a sign for Homewood Suites.
A covered patio area with outdoor seating and a stone wall.
A lobby with a seating area, a reception desk, and a view of the outside.
A spacious hotel lobby with high ceilings, a central seating area, and a bar.

Homewood Suites by Hilton Lafayette, LA

Homewood Suites by Hilton Lafayette, LA
Lafayette

10/10 Exceptional

United States
Don
Homewood Suites by Hilton Lafayette, LA
A large outdoor swimming pool with lounge chairs and palm trees, surrounded by houses.
A group of people at a bar with drinks and a bottle of beer.
A spacious gym with various weightlifting equipment, mirrors, and a large window providing natural light.
A fountain surrounded by a brick wall, palm trees, and a flower bed.

Carriage House Hotel

Carriage House Hotel
River Ranch

10/10 Exceptional

United States
Angel
Carriage House Hotel
A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.
A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".
A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.
A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

Holiday Inn Express & Suites Opelousas by IHG

Holiday Inn Express & Suites Opelousas by IHG
Opelousas

10/10 Exceptional

United States
Robin
Holiday Inn Express & Suites Opelousas by IHG
A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.
A snack display with various chips and snacks.
A poolside area with lounge chairs, a glass table, and a brick building in the background.
A spacious kitchen area with wooden cabinets, a central island, and various appliances.

Hampton Inn Opelousas

Hampton Inn Opelousas
Opelousas

10/10 Exceptional

United States
JERRY
Hampton Inn Opelousas
A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.
A shower enclosure with a glass door, a showerhead, and a handheld shower attachment.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

Spark by Hilton Opelousas

Spark by Hilton Opelousas
Opelousas

10/10 Exceptional

United States
Kevin
Spark by Hilton Opelousas
A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.
A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.
A reception desk with a stone facade, blue walls, and a chandelier.
A hotel room with two beds, a sofa, a chair, and a wooden table.

Days Inn & Suites by Wyndham Opelousas

Days Inn & Suites by Wyndham Opelousas
Opelousas

10/10 Exceptional

United States
Nichole
Days Inn & Suites by Wyndham Opelousas
A modern kitchen with white cabinets, a central island with bar stools, a stainless steel refrigerator, and a brick backsplash.
A spacious living area with a large white island, a ceiling fan, and a view of the outside through large windows.
A modern kitchen with white cabinets, a central island with bar stools, and pendant lighting.
A row of modern townhouses with attached garages, a fire department use sprinkler box, and a parked car.

Enclave 2 Bedroom Luxury Homes

Enclave 2 Bedroom Luxury Homes
Lafayette

10/10 Exceptional

United States
Yvette
Enclave 2 Bedroom Luxury Homes
A modern living room with a sofa, armchair, coffee table, and a dining area with a table and chairs.
A modern kitchen with grey cabinets, stainless steel appliances, a round dining table with chairs, and a potted plant.
A modern kitchen with white cabinets, a wooden staircase, and a view of the living area.
A modern kitchen with white cabinets, a wooden staircase, and a chair.

Enclave 1 Bedroom Suites

Enclave 1 Bedroom Suites
Lafayette

10/10 Exceptional

United States
Holly
Enclave 1 Bedroom Suites
A modern kitchen with grey cabinets, a central island with a sink, and a dining area with wicker chairs.
A row of modern townhouses with attached garages, a clear sky, and a well-maintained lawn.
A modern two-story residential building with a garage, a small front yard, and a clear sky.
A neatly made bed with a headboard, two bedside tables with lamps, a wall-mounted artwork, and a window with blinds.

Enclave 3 Bedroom Luxury Homes

Enclave 3 Bedroom Luxury Homes
Lafayette

10/10 Exceptional

United States
Roderick
Enclave 3 Bedroom Luxury Homes
A lobby with two yellow sofas, a coffee table, and a reception desk.
A hotel room with a flat-screen TV, a desk with a computer, a sofa, and a coffee table. There is a window with curtains, a wall-mounted lamp, and a small painting.
A kitchen with blue cabinets, a coffee machine, a toaster, and a grill.
A modern hotel room with a large bed, a nightstand, a desk, and a window with curtains.

Comfort Inn Lafayette North I-10

Comfort Inn Lafayette North I-10
Lafayette

10/10 Exceptional

United States
Samantha
Comfort Inn Lafayette North I-10
A compact hotel room with a kitchenette, a small table with a chair, and a television mounted on the wall.
A hotel room with a bed, a chair, a dresser, and a framed picture on the wall.
A multi-story motel with a flat facade, balconies, and a parking lot.
A Super 6 Inn sign with a clear view of the surrounding area including a Delta Media billboard and a grassy landscape.

Super 6 Inn

Super 6 Inn
Carencro

10/10 Exceptional

United States
Jimmy
Super 6 Inn
A hotel room with a large bed, two bedside lamps, a desk, a chair, a TV, and an air conditioning unit.
A reception area with two leather chairs, a small table, a wall-mounted TV, and a fireplace.
A modern hotel lobby with a kitchen area, seating arrangements, and a flat-screen TV.
A swimming pool with a 3 FT depth marker, surrounded by lounge chairs and umbrellas, with a building labeled "BOG CITY" in the background.

Best Western Rayne Inn

Best Western Rayne Inn
Rayne

10/10 Exceptional

United States
Sarah
Best Western Rayne Inn
A hotel room with a large bed, a desk with a chair, a chair, and a lamp.
A row of sun loungers with a pair of rolled towels placed on one.
A swimming pool with a geometric tile design, surrounded by palm trees and a fence.
A two-story building with a balcony and a covered porch.

Hotel Klaus

Hotel Klaus
Washington

10/10 Exceptional

United States
Darlene
Hotel Klaus
A reception desk with a blue geometric wall design and a wooden accent.
A hotel room with two beds, a desk, a chair, and a wardrobe.
A kitchenette with two black refrigerators stocked with beverages and snacks, a wooden cabinet with various food items, and a shelf with packaged goods.
A modern breakfast area with a counter displaying various food items and a refrigerated display case.

Holiday Inn Express Breaux Bridge by IHG

Holiday Inn Express Breaux Bridge by IHG
Breaux Bridge

10/10 Exceptional

United States
Jacque
Holiday Inn Express Breaux Bridge by IHG
An outdoor patio with brick flooring, metal tables and chairs, potted plants, and a building with large windows in the background.
A four-poster bed with a white bedspread, a wooden chair, a fireplace, and a chandelier.
A residential area with mature trees, a white house, and parked vehicles.
A gated entrance to a building with a white facade and a covered walkway leading to the entrance.

Mouton Plantation

Mouton Plantation
Sterling Grove Historic District

10/10 Exceptional

United States
Rita
Mouton Plantation
A spacious living area with a dining table, sofa, and a ceiling fan.
A bedroom with a bed, a nightstand, a lamp, a door, and a painting on the wall.
A modern kitchen with white cabinets, stainless steel appliances, a wooden cart, and a dining area with a chair.
A modern, well-lit room with a dining table, wicker chairs, a sofa, and a large mirror on the wall.

The Royal Inn

The Royal Inn
Lafayette

10/10 Exceptional

United States
Yudeika
The Royal Inn

Frequently Asked Questions

What accommodations do travelers recommend in Opelousas?

Guests like Days Inn & Suites by Wyndham Opelousas, Hampton Inn Opelousas and Motel 6 Opelousas, LA.

Can I book a refundable accommodation in Opelousas?

If you need the flexibility to change your travel plans to Opelousas, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Opelousas if I want a vacation rental instead of a hotel?

Browse 5 vacation homes on our site.

What will the weather in Opelousas be like during my vacation?

August and July are typically the warmest months in Opelousas when the average temp is 80°F. January and February are the coldest months when the average temperature is 55°F. August and July are the months with the most rain.

Why should I book my Opelousas accommodation with Hotels.com?

There are lots of reasons to book your Opelousas trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.