A sunset over a calm lake with Spanish moss-covered trees.

Hotels in Opelousas

City, hotel name, or address

Dates

Travelers

I'm traveling for business

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Oct 16 - Oct 18

Where to stay in Opelousas?

A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.

A poolside area with lounge chairs, a glass table, and a brick building in the background.

A gym with treadmills, elliptical machines, and a weightlifting area.

A snack display with various chips and snacks.

1. Hampton Inn Opelousas

Opelousas

$110

$129 total

includes taxes & fees

Oct 14 - Oct 15

A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.

A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.

A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".

2. Holiday Inn Express & Suites Opelousas by IHG

Opelousas

$116

$137 total

includes taxes & fees

Nov 4 - Nov 5

A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.

A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.

A hotel room with two beds, a sofa, a chair, and a wooden table.

A kitchenette with a microwave, coffee machine, and a mini-fridge.

3. Days Inn & Suites by Wyndham Opelousas

Opelousas

$68

$80 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

A modern bathroom with a sink, mirror, toilet, and towel rack.

4. Spark by Hilton Opelousas

Opelousas

$82

$97 total

includes taxes & fees

Nov 6 - Nov 7

A gas station with a covered parking area, a building with multiple windows, and a sign indicating it's now open.

A bathroom with a granite countertop, a sink, a mirror, a towel rack, and a heater.

A hotel room with a bed, a flat-screen TV mounted on the wall, a refrigerator, a small wooden side table, and a mirror.

A multi-story motel with a parking lot.

5. Studio 6 Suites Opelousas, LA

Opelousas

$58

$73 total

includes taxes & fees

Oct 8 - Oct 9

A reception area with a large number '6' on the wall, a flat-screen TV mounted on the wall, and two reception desks.

A hotel room with a dining area, a flat-screen TV mounted on the wall, and two posters advertising travel savings.

A bedroom with a bed, two bedside tables, and a nightstand.

A blue building with a covered entrance and palm trees in the foreground.

6. Motel 6 Opelousas, LA

Opelousas

$57

$67 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with a large bed, a desk with a chair, a chair, and a lamp.

A swimming pool with a geometric tile design, surrounded by palm trees and a fence.

A two-story building with a balcony and a covered porch.

A row of sun loungers with a pair of rolled towels placed on one.

7. Hotel Klaus

Washington

$115

$170 total

includes taxes & fees

Oct 8 - Oct 9

A reception desk with a blue geometric wall design and a wooden accent.

A modern breakfast area with a counter displaying various food items and a refrigerated display case.

A kitchenette with two black refrigerators stocked with beverages and snacks, a wooden cabinet with various food items, and a shelf with packaged goods.

A hotel room with two beds, a desk, a chair, and a wardrobe.

8. Holiday Inn Express Breaux Bridge by IHG

Breaux Bridge

$93

$109 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with two beds, a TV, and a desk.

A modern breakfast area with seating, a coffee machine, and a refrigerator.

A hotel lobby with a reception desk, a flat-screen TV, multiple potted plants, a seating area with a sofa and armchair, and a wooden coffee table.

A modern living room with a sofa, armchair, and coffee table, a flat-screen TV mounted on the wall, and several potted plants.

9. Best Western Ville Platte

Ville Platte

$99

$112 total

includes taxes & fees

Oct 8 - Oct 9

A modern lobby with grey upholstered armchairs, a round wooden ottoman, and a patterned rug.

A Drury Inn & Suites hotel with a stone facade, multiple windows, and a covered entrance.

A hotel room with a sofa, a small table, a TV, a desk with a chair, and a wardrobe.

A spacious indoor dining area with multiple tables and chairs, large windows, and a polished floor.

10. Drury Inn & Suites Lafayette, LA

Lafayette

$117

$138 total

includes taxes & fees

Oct 11 - Oct 12

A hotel laundry area with Whirlpool washers and dryers, a sign with guest laundry guidelines, and a Whirlpool self-service machine.

A Comfort Inn & Suites hotel with a covered entrance and a landscaped driveway.

A hotel room with two beds, a TV, a desk with a computer, a lamp, and a window with curtains.

A reception desk with a wooden finish, a large wall-mounted crescent moon decoration, and several framed certificates on the wall.

11. Comfort Inn & Suites Scott-West Lafayette

Scott

$91

$111 total

includes taxes & fees

Oct 29 - Oct 30

A modern outdoor seating area with fire pit, chairs, and a covered patio.

A modern hotel reception desk with a wooden finish, two monitors, and a sign that reads 'HOME2'.

A modern hotel reception area with a counter, coffee machines, and a fruit display.

A snack display with shelves and a table, a refrigerator with beverages, and a sign stating 'HOME IS WHERE THE SNACKS ARE'.

12. Home2 Suites By Hilton Lafayette I-10

Lafayette

$115

$132 total

includes taxes & fees

Oct 19 - Oct 20

A spacious lobby with a modern design, featuring a seating area, a fireplace, and a refreshment bar.

A self-service beverage station with a variety of drinks, snacks, and a wine cooler.

A Hilton Garden Inn hotel with a covered entrance and a large parking lot.

A spacious living room with a large sofa, ottomans, and a fireplace.

13. Hilton Garden Inn Lafayette/Cajundome

Lafayette

$94

$111 total

includes taxes & fees

Oct 13 - Oct 14

A hotel room with a bed, a TV, a desk, a red sofa, and a striped carpet.

A buffet setup with various food items and a long table covered with a white cloth.

A compact kitchen with dark cabinets, a microwave, a coffee maker, and a sink.

14. Holiday Inn & Suites Lafayette North by IHG

Lafayette

$99

$114 total

includes taxes & fees

Nov 4 - Nov 5

A modern hotel room with a large bed, a TV, a desk, and a carpeted floor.

A gym with treadmills, an elliptical, a bench, and a dumbbell rack.

A modern hotel room with a desk, a blue office chair, a gray sofa, a round wooden coffee table, and two wall-mounted lamps.

A hotel room with a green sofa, wooden tables, and chairs.

15. City Express By Marriott Lafayette

Lafayette

$78

$90 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a reception desk, seating area, and a large cityscape mural.

A lobby with seating, a patterned wall, and a glass entrance.

A hotel room with a large bed, a desk, a chair, a TV, and a window.

16. La Quinta Inn & Suites by Wyndham Lafayette Oil Center

Lafayette

$83

$95 total

includes taxes & fees

Oct 25 - Oct 26

A coffee station with two espresso machines, a coffee dispenser, and various coffee-related items.

A hotel room with a sofa, two beds, a desk, and a TV.

A hotel with a swimming pool, multiple balconies, and a brick facade.

A Holiday Inn Express & Suites hotel with a brick facade, a covered entrance, and palm trees.

17. Holiday Inn Express Hotel & Suites Scott - Lafayette West by IHG

Scott

$109

$133 total

includes taxes & fees

Oct 25 - Oct 26

A modern lobby with a sofa, armchairs, a coffee table, and a reception desk.

A hotel room with a bed, a sofa, a table, a TV, a mirror, and a painting on the wall.

A kitchen with a granite countertop, wooden cabinets, and various appliances including a coffee maker, toaster, and blender. There is a dining table with chairs and a vase of flowers.

A modern living room with a sofa, armchairs, a small table, and a TV mounted on the wall.

18. Best Western Eunice

Eunice

$87

$102 total

includes taxes & fees

Oct 8 - Oct 9

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase to an upper level.

A modern hotel entrance with a covered walkway, clear signage, and a well-maintained exterior.

A living room with a blue sofa, a small coffee table, and a TV on a wooden stand.

A spacious lobby with a high ceiling, a central seating area with sofas, a coffee table, and a staircase leading to an upper level.

19. Wingate by Wyndham Lafayette Airport

Lafayette

$76

$87 total

includes taxes & fees

Oct 13 - Oct 14

View all properties

Get last-minute hotel deals in Opelousas and save more

Sign in to unlock great savings.

A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.

A poolside area with lounge chairs, a glass table, and a brick building in the background.

A gym with treadmills, elliptical machines, and a weightlifting area.

A snack display with various chips and snacks.

Hampton Inn Opelousas

Opelousas

$129

per night

$152 total

includes taxes & fees

A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.

A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.

A hotel room with two beds, a sofa, a chair, and a wooden table.

A kitchenette with a microwave, coffee machine, and a mini-fridge.

Days Inn & Suites by Wyndham Opelousas

Opelousas

$9 off

$78

per night

$92 total

includes taxes & fees

A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.

A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.

A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".

Holiday Inn Express & Suites Opelousas by IHG

Opelousas

$174

per night

$205 total

includes taxes & fees

A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

A modern bathroom with a sink, mirror, toilet, and towel rack.

Spark by Hilton Opelousas

Opelousas

$149

per night

$175 total

includes taxes & fees

A gas station with a covered parking area, a building with multiple windows, and a sign indicating it's now open.

A bathroom with a granite countertop, a sink, a mirror, a towel rack, and a heater.

A hotel room with a bed, a flat-screen TV mounted on the wall, a refrigerator, a small wooden side table, and a mirror.

A multi-story motel with a parking lot.

Studio 6 Suites Opelousas, LA

Opelousas

$7 off

$58

per night

$73 total

includes taxes & fees

A reception area with a large number '6' on the wall, a flat-screen TV mounted on the wall, and two reception desks.

A hotel room with a dining area, a flat-screen TV mounted on the wall, and two posters advertising travel savings.

A bedroom with a bed, two bedside tables, and a nightstand.

A blue building with a covered entrance and palm trees in the foreground.

Motel 6 Opelousas, LA

Opelousas

$69

per night

$81 total

includes taxes & fees

A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.

A poolside area with lounge chairs, a glass table, and a brick building in the background.

A gym with treadmills, elliptical machines, and a weightlifting area.

A snack display with various chips and snacks.

Hampton Inn Opelousas

Opelousas

$129

per night

$152 total

includes taxes & fees

A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.

A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.

A hotel room with two beds, a sofa, a chair, and a wooden table.

A kitchenette with a microwave, coffee machine, and a mini-fridge.

Days Inn & Suites by Wyndham Opelousas

Opelousas

$9 off

$80

per night

$94 total

includes taxes & fees

A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.

A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.

A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".

Holiday Inn Express & Suites Opelousas by IHG

Opelousas

$164

per night

$193 total

includes taxes & fees

A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

A modern bathroom with a sink, mirror, toilet, and towel rack.

Spark by Hilton Opelousas

Opelousas

$119

per night

$140 total

includes taxes & fees

A gas station with a covered parking area, a building with multiple windows, and a sign indicating it's now open.

A bathroom with a granite countertop, a sink, a mirror, a towel rack, and a heater.

A hotel room with a bed, a flat-screen TV mounted on the wall, a refrigerator, a small wooden side table, and a mirror.

A multi-story motel with a parking lot.

Studio 6 Suites Opelousas, LA

Opelousas

$7 off

$58

per night

$73 total

includes taxes & fees

A reception area with a large number '6' on the wall, a flat-screen TV mounted on the wall, and two reception desks.

A hotel room with a dining area, a flat-screen TV mounted on the wall, and two posters advertising travel savings.

A bedroom with a bed, two bedside tables, and a nightstand.

A blue building with a covered entrance and palm trees in the foreground.

Motel 6 Opelousas, LA

Opelousas

$69

per night

$81 total

includes taxes & fees

A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.

A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.

A hotel room with two beds, a sofa, a chair, and a wooden table.

A kitchenette with a microwave, coffee machine, and a mini-fridge.

Days Inn & Suites by Wyndham Opelousas

Opelousas

$93

per night

$219 total

includes taxes & fees

A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.

A poolside area with lounge chairs, a glass table, and a brick building in the background.

A gym with treadmills, elliptical machines, and a weightlifting area.

A snack display with various chips and snacks.

Hampton Inn Opelousas

Opelousas

$178

per night

$418 total

includes taxes & fees

A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

A modern bathroom with a sink, mirror, toilet, and towel rack.

Spark by Hilton Opelousas

Opelousas

$117

per night

$276 total

includes taxes & fees

A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.

A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.

A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".

Holiday Inn Express & Suites Opelousas by IHG

Opelousas

$193

per night

$455 total

includes taxes & fees

A gas station with a covered parking area, a building with multiple windows, and a sign indicating it's now open.

A bathroom with a granite countertop, a sink, a mirror, a towel rack, and a heater.

A hotel room with a bed, a flat-screen TV mounted on the wall, a refrigerator, a small wooden side table, and a mirror.

A multi-story motel with a parking lot.

Studio 6 Suites Opelousas, LA

Opelousas

$15 off

$58

per night

$146 total

includes taxes & fees

A reception area with a large number '6' on the wall, a flat-screen TV mounted on the wall, and two reception desks.

A hotel room with a dining area, a flat-screen TV mounted on the wall, and two posters advertising travel savings.

A bedroom with a bed, two bedside tables, and a nightstand.

A blue building with a covered entrance and palm trees in the foreground.

Motel 6 Opelousas, LA

Opelousas

$65

per night

$153 total

includes taxes & fees

Check out pet-friendly hotels in Opelousas

A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.

A poolside area with lounge chairs, a glass table, and a brick building in the background.

A gym with treadmills, elliptical machines, and a weightlifting area.

A snack display with various chips and snacks.

Hampton Inn Opelousas

Opelousas

$110

$129 total

includes taxes & fees

Oct 14 - Oct 15

A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.

A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.

A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".

Holiday Inn Express & Suites Opelousas by IHG

Opelousas

$116

$137 total

includes taxes & fees

Nov 4 - Nov 5

A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.

A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.

A hotel room with two beds, a sofa, a chair, and a wooden table.

A kitchenette with a microwave, coffee machine, and a mini-fridge.

Days Inn & Suites by Wyndham Opelousas

Opelousas

$68

$80 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

A modern bathroom with a sink, mirror, toilet, and towel rack.

Spark by Hilton Opelousas

Opelousas

$82

$97 total

includes taxes & fees

Nov 6 - Nov 7

A gas station with a covered parking area, a building with multiple windows, and a sign indicating it's now open.

A bathroom with a granite countertop, a sink, a mirror, a towel rack, and a heater.

A hotel room with a bed, a flat-screen TV mounted on the wall, a refrigerator, a small wooden side table, and a mirror.

A multi-story motel with a parking lot.

Studio 6 Suites Opelousas, LA

Opelousas

$58

$73 total

includes taxes & fees

Oct 8 - Oct 9

A reception area with a large number '6' on the wall, a flat-screen TV mounted on the wall, and two reception desks.

A hotel room with a dining area, a flat-screen TV mounted on the wall, and two posters advertising travel savings.

A bedroom with a bed, two bedside tables, and a nightstand.

A blue building with a covered entrance and palm trees in the foreground.

Motel 6 Opelousas, LA

Opelousas

$57

$67 total

includes taxes & fees

Oct 26 - Oct 27

View all properties

Go beyond your typical stay in Opelousas

pet friendly image

Pool image

hot tub image

Family friendly image

spa image

Apartment image

Condo image

Cottage image

Our prices for hotels in Opelousas are cheapest in December

Top landmarks in Opelousas

Evangeline Downs Racetrack & Casino

Evangeline Downs Racetrack & Casino is 1.4 mi (2.2 km) from central Opelousas, why not stop by during your stay.

St. Landry Catholic Church

8.2/10 (26 reviews)

St. Landry Catholic Church is 0.7 mi (1.1 km) from central Opelousas, why not stop by during your stay.

Louisiana Orphan Train Museum

8.0/10 (17 reviews)

If museums are on your list of things to see in Opelousas, then you might want to head to Louisiana Orphan Train Museum. If you want to see more of the museums in Opelousas, you can easily walk to Fireman's Museum.

Opelousas Historic District

If you're planning a bit of sightseeing during your trip, head to Opelousas Historic District— just one of the monuments in central Opelousas.

Opelousas Museum And Interpretive Center

The center of Opelousas is home to cultural attractions like Opelousas Museum And Interpretive Center, so you might want to stop by during your stay. If you want to experience more of the culture Opelousas has to offer, head to St. Landry Catholic Church, Louisiana Orphan Train Museum, and Evangeline Downs Racetrack & Casino.

Fireman's Museum

If museums are on your list of things to see, then you might want to head to Fireman's Museum, located in the heart of Opelousas.If you want to see more of the museums in Opelousas, you can easily walk to Louisiana Orphan Train Museum or Opelousas Museum And Interpretive Center.

Opelousas Public Library

Opelousas Public Library is worth a visit when in central Opelousas.

North Park

North Park is worth a visit, located 1.2 mi (1.9 km) from central Opelousas.

Learn more about Opelousas

Savor spicy Cajun cuisine at local eateries like Palace Cafe, then tap your toes to zydeco music. Explore the Opelousas Museum and Interpretive Center to uncover the city's rich history as 'The Spice Capital of the World.'

See all hotels in Opelousas

A sunset over a calm lake with Spanish moss-covered trees.

Check out reviews of Opelousas hotels guests love

A Holiday Inn Express & Suites building with a covered entrance and a sign indicating the entrance.

A modern kitchen with a dining area, featuring a wooden table, blue chairs, and a hanging pendant light.

A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A reception area with two reception desks, a blue wall with geometric patterns, and a sign reading "Holiday Inn Express".

Holiday Inn Express & Suites Opelousas by IHG

Opelousas

10/10 Exceptional

United States

Robin

A Hampton Inn hotel with a clear entrance, a flagpole with the American flag, and a parking area.

A poolside area with lounge chairs, a glass table, and a brick building in the background.

A gym with treadmills, elliptical machines, and a weightlifting area.

A snack display with various chips and snacks.

Hampton Inn Opelousas

Opelousas

10/10 Exceptional

United States

JERRY

A hotel room with a large bed, bedside tables, a TV, a wardrobe, and a window with curtains.

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A hotel room with a bed, a sofa, a bedside table with a lamp, and a wall-mounted artwork.

A modern bathroom with a sink, mirror, toilet, and towel rack.

Spark by Hilton Opelousas

Opelousas

10/10 Exceptional

United States

Kevin

A hotel room with a large bed, a sofa, a small table, a nightstand, and a wall-mounted lamp.

A modern living room with a stone accent wall, a flat-screen TV, a glass coffee table, and a beige sofa.

A hotel room with two beds, a sofa, a chair, and a wooden table.

A kitchenette with a microwave, coffee machine, and a mini-fridge.

Days Inn & Suites by Wyndham Opelousas

Opelousas

10/10 Exceptional

United States

Nichole

A hotel room with a large bed, a desk with a chair, a chair, and a lamp.

A swimming pool with a geometric tile design, surrounded by palm trees and a fence.

A two-story building with a balcony and a covered porch.

A row of sun loungers with a pair of rolled towels placed on one.

Hotel Klaus

Washington

10/10 Exceptional

United States

Darlene

A modern outdoor seating area with fire pit, chairs, and a covered patio.

A modern hotel reception desk with a wooden finish, two monitors, and a sign that reads 'HOME2'.

A modern hotel reception area with a counter, coffee machines, and a fruit display.

A snack display with shelves and a table, a refrigerator with beverages, and a sign stating 'HOME IS WHERE THE SNACKS ARE'.

Home2 Suites By Hilton Lafayette I-10

Lafayette

10/10 Exceptional

United States

Kalu

A modern lobby with grey upholstered armchairs, a round wooden ottoman, and a patterned rug.

A Drury Inn & Suites hotel with a stone facade, multiple windows, and a covered entrance.

A hotel room with a sofa, a small table, a TV, a desk with a chair, and a wardrobe.

A spacious indoor dining area with multiple tables and chairs, large windows, and a polished floor.

Drury Inn & Suites Lafayette, LA

Lafayette

10/10 Exceptional

United States

salvatore

A modern kitchen with white cabinets, a central island with bar stools, a stainless steel refrigerator, and a brick backsplash.

A bedroom with a bed, nightstands, a ceiling fan, a large window, and a potted plant.

A row of modern townhouses with attached garages, a fire department use sprinkler box, and a parked car.

A spacious living area with a large white island, a ceiling fan, and a view of the outside through large windows.

Enclave 2 Bedroom Luxury Homes

Lafayette

10/10 Exceptional

United States

Yvette

A modern living room with a sofa, armchair, coffee table, and a dining area with a table and chairs.

A modern kitchen with white cabinets, a wooden staircase, and a chair.

A modern kitchen with grey cabinets, stainless steel appliances, a round dining table with chairs, and a potted plant.

A modern apartment with a living room, dining area, and kitchen.

Enclave 1 Bedroom Suites

Lafayette

10/10 Exceptional

United States

Holly

A small, single-story house with a porch and a wooden fence.

A sunlit room with a table, two chairs, a vase with flowers, and a view of a green landscape through large windows.

A bedroom with a large bed, a bathroom with a bathtub, and a view of trees through the window.

A wooden sign with the text "Prairie Haven Cottage".

Maison D'Memoire Bed & Breakfast Cottages

Rayne

10/10 Exceptional

United States

Kim

A reception desk with a blue geometric wall design and a wooden accent.

A modern breakfast area with a counter displaying various food items and a refrigerated display case.

A kitchenette with two black refrigerators stocked with beverages and snacks, a wooden cabinet with various food items, and a shelf with packaged goods.

A hotel room with two beds, a desk, a chair, and a wardrobe.

Holiday Inn Express Breaux Bridge by IHG

Breaux Bridge

10/10 Exceptional

United States

Jacque

A hotel room with a bed, a TV, a desk, a red sofa, and a striped carpet.

A buffet setup with various food items and a long table covered with a white cloth.

A compact kitchen with dark cabinets, a microwave, a coffee maker, and a sink.

Holiday Inn & Suites Lafayette North by IHG

Lafayette

10/10 Exceptional

United States

Anonymous traveler

An outdoor patio with brick flooring, metal tables and chairs, potted plants, and a building with large windows in the background.

A gated entrance to a building with a white facade and a covered walkway leading to the entrance.

A four-poster bed with a white bedspread, a wooden chair, a fireplace, and a chandelier.

A dining room with a long wooden table set for a meal, large windows, and a chandelier.

Mouton Plantation

Sterling Grove Historic District

10/10 Exceptional

United States

Rita

A hotel laundry area with Whirlpool washers and dryers, a sign with guest laundry guidelines, and a Whirlpool self-service machine.

A Comfort Inn & Suites hotel with a covered entrance and a landscaped driveway.

A hotel room with two beds, a TV, a desk with a computer, a lamp, and a window with curtains.

A reception desk with a wooden finish, a large wall-mounted crescent moon decoration, and several framed certificates on the wall.

Comfort Inn & Suites Scott-West Lafayette

Scott

10/10 Exceptional

United States

Kevin

A spacious indoor area with multiple seating options, including tables and chairs, and a large window providing natural light.

A modern hotel room with a living area, kitchenette, and a view of the city.

A Staybridge Suites hotel with a brick facade, multiple windows, and a covered entrance.

A gym with treadmills, exercise bikes, and a mirrored wall.

Staybridge Suites Lafayette by IHG

Lafayette

10/10 Exceptional

United States

James

A spacious lobby with a reception desk, seating area, and a large cityscape mural.

A lobby with seating, a patterned wall, and a glass entrance.

A hotel room with a large bed, a desk, a chair, a TV, and a window.

La Quinta Inn & Suites by Wyndham Lafayette Oil Center

Lafayette

10/10 Exceptional

United States

Tiana

A modern lobby with a central bar area, seating arrangements, and a reception desk.

A hotel room with a bed, a desk, a microwave, a coffee maker, and a mini fridge.

A reception area with a curved wooden counter, glass panels, and a large wall with text and geometric patterns.

A brick patio with a light-colored sectional sofa and two round tables.

SpringHill Suites by Marriott Lafayette South at River Ranch

River Ranch

10/10 Exceptional

United States

Charles

A modern lobby with a reception desk, seating area, and a large plant.

A breakfast bar with various food items and a coffee station.

A modern living room with a gray sofa, yellow ottoman, and a round coffee table. There is a desk with a chair and a lamp. The room has a wooden floor and white walls with artwork.

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a red roof.

Comfort Suites Oil Center

Lafayette

10/10 Exceptional

United States

Ross

Private kitchen

A modern courtyard with white furniture, a central seating area, and a small lawn.

Private kitchen

A sign for Stay Apt Suites with a modern building in the background.

stayAPT Suites Lafayette South

Lafayette

10/10 Exceptional

United States

Alyssa

Frequently Asked Questions

What accommodations do travelers recommend in Opelousas?

Guests like Days Inn & Suites by Wyndham Opelousas, Hampton Inn Opelousas and Motel 6 Opelousas, LA.

Can I book a refundable accommodation in Opelousas?

If you need the flexibility to change your travel plans to Opelousas, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Opelousas if I want a vacation rental instead of a hotel?

Browse 5 vacation homes on our site.

What will the weather in Opelousas be like during my vacation?

August and July are typically the warmest months in Opelousas when the average temp is 80°F. January and February are the coldest months when the average temperature is 55°F. August and July are the months with the most rain.

Why should I book my Opelousas accommodation with Hotels.com?

There are lots of reasons to book your Opelousas trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.