Hotels in Depew

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Where to stay in Depew?

A hotel room with a bed, a sofa, a desk with a chair, a television, and a minibar.

A spacious dining area with multiple wooden tables and chairs, a kitchen area with a counter and appliances, and a tiled ceiling with a grid pattern.

A Sleep Inn & Suites hotel with a modern design, featuring a prominent entrance, a covered walkway, and a well-maintained lawn.

A spacious lobby with a staircase, a reception desk, and a vending machine.

1. Sleep Inn & Suites Buffalo Airport

Buffalo

$81

$92 total

includes taxes & fees

Oct 27 - Oct 28

A bar area with multiple stools, a counter, and TVs displaying sports.

A hotel room with a beige sofa, a wooden coffee table, a TV, and a bed with a wooden headboard.

A hotel room with a bed, a desk, a television, and a couch.

A gym with treadmills, elliptical machines, and weightlifting equipment.

2. Buffalo Airport Hotel

Buffalo

$94

$106 total

includes taxes & fees

Sep 28 - Sep 29

A spacious lobby with high ceilings, a grand staircase, and a gift shop.

A bar area with red upholstered bar stools, a bar counter, and a chandelier.

A hotel room with two beds, a desk, a chair, a coffee machine, and a large window with curtains.

A bar area with leather barstools, a bar counter, and a television screen.

3. The Delavan Hotel & Spa

Bowmansville

$110

$125 total

includes taxes & fees

Oct 12 - Oct 13

An indoor swimming pool with clear water, lounge chairs, and a lifeguard stand.

A modern dining area with yellow chairs, wooden tables, and a central counter with a coffee machine.

A modern hotel lobby with a blue accent wall, a reception desk, a sofa, a chair, and a coffee table.

A hotel room with a bed, a desk, a chair, a sofa, a small round table, and a TV mounted on the wall.

4. Comfort Inn & Suites Buffalo Airport

Buffalo

$114

$130 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a bed, desk, and a large mirror with built-in lighting.

A large industrial building with a silo-like structure and a tower on top, surrounded by calm water with several small boats.

A Holiday Inn Express hotel with a prominent entrance and a clear blue sky.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a stone wall.

5. Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Buffalo

$129

$147 total

includes taxes & fees

Oct 14 - Oct 15

A pool area with a hot tub, lounge chairs, and a lifeguard chair.

A modern hotel lobby with a beige sofa, green armchairs, a dining area, and a kitchen area with a refrigerator stocked with beverages.

A modern hotel lobby with a central bar area, seating arrangements, and pendant lighting.

6. Fairfield Inn & Suites by Marriott Buffalo Airport

Buffalo

$139

$162 total

includes taxes & fees

Oct 18 - Oct 19

A room with two blue armchairs, a green armchair, and a woven ottoman. A large landscape painting is on the wall.

A coffee station with a coffee machine, cups, and a display of pastries.

A hotel entrance with a glass door, stone facade, and a covered walkway.

A La Quinta Inn with a red and white exterior, a covered entrance, and a parking lot with several cars.

7. La Quinta Inn by Wyndham Buffalo Airport

Buffalo

$74

$84 total

includes taxes & fees

Sep 30 - Oct 1

A patio area with a fire pit, outdoor furniture, and a pergola.

An indoor swimming pool with lounge chairs and umbrellas, surrounded by walls with windows and doors.

A modern hotel lobby with a fireplace, seating area, and a 'Suite Shop' with refrigerated display cases.

A modern hotel lobby with a reception desk, seating area, and a fireplace.

8. Homewood Suites by Hilton Buffalo Airport

Buffalo

$131

$153 total

includes taxes & fees

Oct 5 - Oct 6

A hotel lobby with a bar area, seating arrangements, and large windows providing natural light.

A snack bar with refrigerated drinks, chips, and cookies.

A Hampton Inn & Suites with a clear entrance, a covered parking area, and a brick facade.

9. Hampton Inn & Suites Buffalo Airport

Buffalo

$130

$152 total

includes taxes & fees

Oct 18 - Oct 19

An outdoor seating area with orange chairs and tables, a covered area with umbrellas, and a building entrance with glass doors and interior lighting.

A modern hotel with a prominent 'Aloft' sign, large windows, and a well-lit entrance.

A modern cafe with a wooden counter, clear menu boards, and a variety of food and drink dispensers.

A gym with treadmills, elliptical machines, and weight machines.

10. Aloft by Marriott Buffalo Airport

Buffalo

$115

$131 total

includes taxes & fees

Oct 25 - Oct 26

A modern coffee station with a coffee machine, a variety of coffee pods, and a selection of snacks and condiments.

A modern living room with large windows, a fireplace, and a comfortable seating area.

A modern hotel with a prominent sign, a parking lot, and a well-maintained lawn.

A modern reception area with a blue and white color scheme, a large window, and a green wall feature.

11. Best Western Buffalo Inn & Suites

Buffalo

$100

$114 total

includes taxes & fees

Oct 5 - Oct 6

A modern living room with a sofa, armchair, and coffee table, a black and white abstract wall art, a black cabinet with decorative items, and a ceiling light.

A hotel room with a bed, a chair, and a small table.

A fitness room with treadmills and a stationary bike, a television on the wall, and a window with blinds.

A reception area with a wooden counter, a potted plant, a painting on the wall, a clock, and a window with blinds.

12. Baymont by Wyndham Buffalo

Buffalo

$86

$100 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with a central seating area, a shop in the background, and potted plants along the walkway.

A modern bar area with a long counter, multiple seating options, and a unique ceiling design.

A Hilton Garden Inn hotel with a well-lit entrance, outdoor seating area, and landscaped garden.

An outdoor patio with a fire pit, seating, and string lights.

13. Hilton Garden Inn Buffalo Airport

Buffalo

$163

$191 total

includes taxes & fees

Oct 18 - Oct 19

A hotel pool area with a hot tub, lounge chairs, and a seating area with tables.

A Courtyard by Marriott hotel with a covered entrance, brick facade, and multiple windows.

An outdoor patio area with a stone fire pit surrounded by wicker furniture and cushions.

A spacious hotel lounge with multiple seating areas, a flat-screen TV, and a large window providing natural light.

14. Courtyard Buffalo Airport

Buffalo

$165

$193 total

includes taxes & fees

Oct 18 - Oct 19

A Holiday Inn Express building with a covered entrance, a flag, and a sign indicating the address.

A modern hotel lobby with a circular glass table surrounded by chairs, a bar area, and seating with orange cushions.

A large indoor swimming pool with a curved edge, a lounge area with a sofa, and a door leading to another room.

A hotel room with a large bed, a desk with a flat-screen TV, a sofa, a lamp, and a window with curtains.

15. Holiday Inn Express Cheektowaga North East by IHG

Buffalo

$142

$166 total

includes taxes & fees

Oct 18 - Oct 19

A patio area with outdoor seating, a barbecue grill, and a stone wall.

A modern hotel lobby with a central seating area, a reception desk, and a colorful mural.

A modern lounge area with seating, tables, and hanging chairs.

A modern indoor space with a foosball table, seating areas, a mural, and a television screen.

16. Tru by Hilton Williamsville Buffalo Airport

Buffalo

$127

$144 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with a water fountain, surrounded by greenery and modern architecture with a glass ceiling.

A hotel room with two beds, a desk with a television, and a view of the outdoors.

A hotel room with a bed, a TV mounted on the wall, a small table with a vase and candles, a chair, and a view of the city at night.

A lobby with a reception desk, seating area, and a patterned carpet.

17. M Hotel Buffalo

Buffalo

$103

$117 total

includes taxes & fees

Sep 28 - Sep 29

A pool area with clear blue water, a diving board, and several lounge chairs.

A modern conference room with tables and chairs, large windows, and a carpeted floor.

A hotel with a modern design, featuring a prominent sign for TownePlace Suites by Marriott.

A modern hotel lobby with a kitchen area, a seating area, and a refrigerator stocked with beverages.

18. TownePlace Suites Buffalo Airport

Buffalo

$166

$193 total

includes taxes & fees

Oct 18 - Oct 19

A Hampton Inn hotel with a modern facade, large windows, and a well-maintained parking lot.

An outdoor patio with a table and chairs, a blue sofa, and a large umbrella.

An indoor swimming pool with blue and yellow lounge chairs, large windows, and a tiled floor.

A vending machine with snacks and drinks, including Coca-Cola, Sprite, and various chips.

19. Hampton Inn Buffalo-Airport / Galleria Mall

Buffalo

$137

$160 total

includes taxes & fees

Oct 18 - Oct 19

A buffet setup with various food items and utensils.

A hotel room with a sofa, a bed, a desk, and a chair. There are lamps on the desk and bedside tables.

A hotel reception desk with a large mirror, a chandelier, and a 'HOTEL' sign.

A building with a large illuminated sign reading "Russells STEAKS - CHOPS - AND MORE".

20. Salvatores Grand Hotel

Buffalo

$169

$192 total

includes taxes & fees

Sep 28 - Sep 29

View all properties

Go beyond your typical stay in Depew

Pet friendly

Pool

Hot tub

Family friendly

Check out reviews of Depew hotels guests love

Holiday Inn Express Grand Island - Niagara Falls by IHG

8/10 Good

"We enjoyed our stay very much! The elevator by main desk actually closed or tried to a couple times almost like sensor was not reading a person there and pretty quick needs to be looked at slammed my arm a couple times. Everyone was very helpful. The breakfast was wonderful all in all a great trip!"

La Quinta Inn & Suites by Wyndham Buffalo Amherst

8/10 Good

"Only complaint was that there was no decaf coffee and seating was awkward. The booth benches were low compared to the tables and there weren’t many tables with just chairs."

Buffalo Airport Hotel

8/10 Good

"The rooms were nice, clean and well maintained."

M Hotel Buffalo

8/10 Good

"The hotel was good, stayed two nights to go to a local fossil pit and Niagara Falls. It was 30 mins away from both and easy access to the highway. The mall is in walking distance, which was nice since we needed emergency pants. For the price, I would stay there again."

Best Western Buffalo Inn & Suites

8/10 Good

"Great location, our room was perfect for 5!"

Hampton Inn Buffalo - Amherst, NY

10/10 Excellent

"Good location. Helpful staff. Ample and varied breakfast."

Sleep Inn & Suites Buffalo Airport

10/10 Excellent

"Great room and area. Breakfast not so great."

Comfort Inn & Suites Niagara Falls Blvd USA

10/10 Excellent

"Un hotel muy acogedor y tranquilo. Desayuno muy variado. Me encantó."

Studio 6 Corporate Extended Stay Buffalo Amherst NY

10/10 Excellent

"The staff was very nice and helpful."

Frequently asked questions

What accommodations do travelers like in Depew?

Guests like M Hotel Buffalo, Buffalo Airport Hotel and Garden Place Hotel.

Can I book a refundable hotel in Depew?

If you want the flexibility to change your travel plans to Depew, most properties offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Depew if I want a vacation home instead of a traditional hotel?

You'll find 5 vacation homes on our site. In addition, you can choose from 6 apartments.

What will the weather in Depew be like during my trip?

The warmest months in Depew are usually July and August with an average temp of 67°F. January and February are the chilliest months when the average temp is 29°F. The rainiest months are April and June.

Why should I book my Depew hotel with Hotels.com?

There are plenty of reasons to book your Depew travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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