A sign for the Key West Museum of Art & History at the Custom House.

Business Hotels in Key West

Where to?

Dates

November 2026

December 2026

I'm traveling for business

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Business Hotels in Key West

A pool area with lounge chairs and gazebos, surrounded by palm trees.

1. DoubleTree Resort by Hilton Grand Key - Key West

Key West

$186 total

includes taxes & fees

Nov 17 - Nov 18

A pool area with lounge chairs and palm trees, surrounded by boats and a sunset in the background.

2. The Perry Hotel & Marina Key West

Stock Island

$205 total

includes taxes & fees

Nov 30 - Dec 1

A hotel with a swimming pool, sun loungers, and palm trees.

3. Blue Flamingo Resort Key West

New Town

$197 total

includes taxes & fees

Nov 15 - Nov 16

A pool area with lounge chairs and umbrellas, surrounded by palm trees.

4. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

New Town

$179 total

includes taxes & fees

Nov 18 - Nov 19

A marina with boats docked, a pool area, and a building with a white facade.

5. Hilton Key West Resort & Marina

Stock Island

$191 total

includes taxes & fees

Nov 17 - Nov 18

A swimming pool with lounge chairs and palm trees.

6. Hilton Garden Inn Key West / The Keys Collection

New Town

$157 total

includes taxes & fees

Nov 17 - Nov 18

A pool area with lounge chairs and a cabana.

7. Ocean Key Resort - A Noble House Resort

Key West Historic District

$367 total

includes taxes & fees

Nov 29 - Nov 30

A spacious living room with a balcony, a ceiling fan, and a large window offering a view of the ocean.

8. The Laureate Key West

New Town

$207 total

includes taxes & fees

Nov 15 - Nov 16

A beach with a wooden pier, palm trees, and beach umbrellas.

9. The Reach Key West, Curio Collection by Hilton

Old Town Key West

$296 total

includes taxes & fees

Nov 30 - Dec 1

A hotel with a swimming pool, balconies, and a view of the sea.

10. Hyatt Centric Key West Resort and Spa

Key West Historic District

$345 total

includes taxes & fees

Dec 1 - Dec 2

A pool area with lounge chairs and umbrellas, surrounded by palm trees and a view of the ocean.

11. Hampton Inn Key West FL

Key West

$212 total

includes taxes & fees

Nov 30 - Dec 1

A resort pool with clear blue water, surrounded by palm trees and lounge chairs.

12. Havana Cabana at Key West

New Town

$225 total

includes taxes & fees

Nov 29 - Nov 30

A swimming pool with water splashing, surrounded by palm trees and a building in the background.

13. Silver Palms Inn & Historic Homes

Old Town Key West

$258 total

includes taxes & fees

Dec 1 - Dec 2

A wooden deck with wicker furniture and a glass balustrade overlooking a beach.

14. Casa Marina Key West, Curio Collection by Hilton

Old Town Key West

$322 total

includes taxes & fees

Nov 23 - Nov 24

A wooden boardwalk with a palm tree and lamp post, leading to a waterfront.

15. Courtyard by Marriott Key West Waterfront

Northside Resort

$211 total

includes taxes & fees

Nov 30 - Dec 1

A wooden archway leading to a pool area surrounded by lush tropical vegetation.

16. Parrot Key Hotel & Villas

Northside Resort

$224 total

includes taxes & fees

Dec 1 - Dec 2

A multi-story hotel with a pink facade, multiple balconies, and a prominent 'LA CONCHA' sign.

17. La Concha Key West, Autograph Collection

Key West Historic District

$267 total

includes taxes & fees

Nov 30 - Dec 1

A covered balcony with white Adirondack chairs and a small table with flowers, overlooking a turquoise sea and distant shoreline.

18. Opal Key Resort & Marina, Key West

Old Town Key West

$331 total

includes taxes & fees

Nov 29 - Nov 30

A pool area with lounge chairs and candles, surrounded by palm trees and a building in the background.

19. Tropical Inn

Old Town Key West

$238 total

includes taxes & fees

Nov 15 - Nov 16

A poolside area with lounge chairs, umbrellas, and a pergola.

20. Ella's Cottages - Key West Historic Inns

Old Town Key West

$298 total

includes taxes & fees

Nov 29 - Nov 30

View all properties

Top neighborhoods in Key West

A large red brick building with arched windows and a prominent entrance.

Old Town Key West

Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

See properties

A row of pastel-colored houses with white railings and a clear blue sky.

New Town

New Town gives you a quieter slice of Key West living away from the tourist crowds. This peaceful residential area offers wide streets for strolling and a glimpse into authentic island life. Nearby Smathers Beach and the Key West Tropical Forest provide natural escapes when you need a break from the bustle. Budget-friendly chain hotels and vacation rentals make this area wallet-friendly for longer stays. Cuban-American eateries and family restaurants offer affordable meals, while shopping plazas with grocery stores help you feel right at home. A car is handy, but free parking is plentiful throughout the neighborhood.

See properties

The Monroe County Courthouse with a clock tower, surrounded by trees and a clear blue sky.

Downtown Key West

Downtown Key West dazzles with its historic charm and non-stop energy. Wander Duval Street's lively scene, visit Hemingway's famous six-toed cat sanctuary, or catch the sunset celebration at Mallory Square where fire-breathers and musicians perform against stunning Gulf backdrops. The neighborhood's Victorian mansions with gingerbread trim and weathered coral stone churches create a unique tropical atmosphere. The area serves up fresh seafood from casual waterfront joints to upscale restaurants. Most attractions sit within a walkable six-block radius, though you can hop on the Conch Tour Train when your feet need a break. Boutique hotels and historic inns with tropical courtyards offer charming places to crash after experiencing the legendary bar scene.

See properties

A white lighthouse surrounded by lush greenery and a white picket fence.

Key West Historic District

Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

See properties

A street with a pharmacy, a theater, and a yellow building.

Uptown - Upper Duval

Key West's Uptown - Upper Duval neighborhood has a host of places to visit such as Duval Street and Florida Keys Beaches.

See properties

Top landmarks in Key West

Duval Street

9.2/10 (20,928 reviews)

If you want to give your credit card some exercise, head out to Duval Street, a popular place for shoppers in Key West Historic District. Splash some more cash at Mallory Dock and We Cycle Key West.

See properties

A two-story colonial-style building with a balcony, surrounded by lush greenery and palm trees.

Ernest Hemingway Home and Museum

9.2/10 (8,543 reviews)

Ernest Hemingway Home and Museum is just one of the attractions in Old Town Key West, Key West so you might want to stop by during your trip. Why not take a stroll along the beaches and watch the sunset while you're here? If you want to experience more of the culture Key West has to offer, head to Key West Lighthouse and Keeper's Quarters Museum, Duval Street, and Key West Butterfly and Nature Conservatory.

See properties

About the destination

Visitors speak favorably about all that Key West has to offer, including its seaside, live music, bars, and festivals. Activities like biking give you a chance to enjoy the outdoors while you're in town. Beachcombers can spend the day at Florida Keys Beaches when the weather is nice. While you're here, make time to enjoy other sights such as Duval Street.