Hotels in St. Charles
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White Valley Motel
White Valley MotelSt. Charles
5.6 out of 10, (129 reviews)
cleanliness Cozy riverside motel in St. Charles with easy access to Whitewater River.
The price is $69
$77 total
includes taxes & fees
Apr 1 - Apr 2

Big River Escape Grandview Manse
Big River Escape Grandview ManseAltura
10.0 out of 10, Exceptional, (4 reviews)
cleanliness Charming vacation home in Altura with kitchen amenities and natural surroundings.
The price is $370
$397 total
includes taxes & fees
Apr 1 - Apr 2

Days Inn by Wyndham Winona
Days Inn by Wyndham WinonaWinona
7.8 out of 10, Good, (1,000 reviews)
cleanliness Modern Days Inn by the Mississippi with complimentary amenities and fitness.
The price is $68
$76 total
includes taxes & fees
Apr 2 - Apr 3

The Wen Inn formerly Andor Wenneson
The Wen Inn formerly Andor WennesonPeterson
9.8 out of 10, Exceptional, (62 reviews)
cleanliness Escape to a charming inn adjacent to Peterson's golf course, with hiking trails nearby.
The price is $87
$96 total
includes taxes & fees
Apr 14 - Apr 15

Big River Escape Riverside Cabins
Big River Escape Riverside CabinsCochrane
9.2 out of 10, Wonderful, (44 reviews)
cleanliness Unwind in riverside cabins with kitchen convenience, just minutes from Mississippi River.
The price is $98
$104 total
includes taxes & fees
Apr 2 - Apr 3

AmericInn by Wyndham Winona
AmericInn by Wyndham WinonaWinona
9.2 out of 10, Wonderful, (920 reviews)
cleanliness Stay minutes from Winona State University with hot tub and complimentary perks.
The price is $116
$130 total
includes taxes & fees
Apr 12 - Apr 13

Stone Mill Hotel & Suites
Stone Mill Hotel & SuitesLanesboro
9.2 out of 10, Wonderful, (669 reviews)
cleanliness Experience the serenity of countryside living at this golf-adjacent retreat in Lanesboro.
The price is $105
$113 total
includes taxes & fees
Apr 1 - Apr 2

Green Gables Inn
Green Gables InnLanesboro
9.6 out of 10, Exceptional, (73 reviews)
cleanliness Explore the charm of Lanesboro with a quaint inn near Root River and local parks.
The price is $102
$109 total
includes taxes & fees
Apr 1 - Apr 2

The Rushford Inn
The Rushford InnRushford
The price is $159
$176 total
includes taxes & fees
Apr 1 - Apr 2

Spark by Hilton Rochester South
Spark by Hilton Rochester SouthRochester
9.4 out of 10, Exceptional, (421 reviews)
cleanliness Cozy lodging near Mayo Clinic with complimentary breakfast and indoor pool access.
The price is $73
$84 total
includes taxes & fees
Apr 12 - Apr 13

Big River Escape Parkside Bungalow
Big River Escape Parkside BungalowWinona
10.0 out of 10, Exceptional, (1 review)
cleanliness Quiet cottage retreat near Winona Station with free WiFi and parking.
The price is $206
$230 total
includes taxes & fees
Apr 5 - Apr 6

Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHGRochester
8.8 out of 10, Excellent, (1,006 reviews)
cleanliness Modern rooms near Mayo Clinic with indoor pool and free hot breakfast daily.
The price is $99
$114 total
includes taxes & fees
Apr 5 - Apr 6

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic SRochester
7.2 out of 10, Good, (1,032 reviews)
cleanliness Convenient location near Mayo Clinic with free daily breakfast and on-site fitness.
The price is $72
$83 total
includes taxes & fees
Apr 1 - Apr 2

AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo ClinicRochester
8.0 out of 10, Very Good, (1,244 reviews)
cleanliness Peaceful retreat near Mayo Clinic with serene atmosphere and indoor pool.
The price is $73
$84 total
includes taxes & fees
Apr 5 - Apr 6

Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic AreaRochester
9.0 out of 10, Wonderful, (955 reviews)
cleanliness Restful retreat near Mayo Clinic with 24-hour fitness center and complimentary perks.
The price is $68
$78 total
includes taxes & fees
Apr 19 - Apr 20

Carriage House B&B
Carriage House B&BHistoric Downtown Winona
9.6 out of 10, Exceptional, (89 reviews)
cleanliness Experience Victorian elegance in Winona, with easy access to hiking trails.
The price is $148
$165 total
includes taxes & fees
Apr 1 - Apr 2

Hampton Inn Rochester-South
Hampton Inn Rochester-SouthRochester
9.0 out of 10, Wonderful, (1,009 reviews)
cleanliness Peaceful hotel near Mayo Clinic with indoor pool and daily complimentary breakfast.
The price is $86
$99 total
includes taxes & fees
Apr 26 - Apr 27

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHGDowntown Rochester
8.8 out of 10, Excellent, (971 reviews)
cleanliness Relax in quiet comfort with Mayo Clinic just a 15-minute walk away from this hotel.
The price is $93
$107 total
includes taxes & fees
Apr 4 - Apr 5

Baymont by Wyndham Rochester Mayo Clinic Area
Baymont by Wyndham Rochester Mayo Clinic AreaRochester
7.0 out of 10, Good, (756 reviews)
The price is $60
$69 total
includes taxes & fees
Apr 6 - Apr 7

Birch Hill Suite Rochester – Med City
Birch Hill Suite Rochester – Med CityRochester
7.8 out of 10, Good, (25 reviews)
cleanliness Stylish retreat close to Mayo Clinic with thoughtful traveler amenities.
The price is $59
$68 total
includes taxes & fees
Apr 5 - Apr 6
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in St. Charles
Pet friendly
Learn more about St. Charles
St. Charles is well-known for its attractions such as Whitewater State Park and Whitewater River.

Check out reviews of St. Charles hotels guests love

Kahler Inn and Suites - Mayo Clinic Area
10/10 Excellent




































































