Hotels in St. Charles
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Where to stay in St. Charles?
White Valley Motel
White Valley Motel
2.5 star property
St. Charles
5.6 out of 10, (128)
5.6/10
(128)
- Cozy riverside motel in St. Charles with easy access to Whitewater River.
The price is $69
$69
$77 total
includes taxes & fees
Jan 5 - Jan 6
AmericInn by Wyndham Winona
AmericInn by Wyndham Winona
2.5 star property
Winona
9.0 out of 10, Wonderful, (898)
9.0/10
Wonderful
(898)
- Stay minutes from Winona State University with hot tub and complimentary perks.
The price is $101
$101
$113 total
includes taxes & fees
Jan 11 - Jan 12
Days Inn by Wyndham Winona
Days Inn by Wyndham Winona
2.0 star property
Winona
7.8 out of 10, Good, (1003)
7.8/10
Good
(1003)
- Modern Days Inn by the Mississippi with complimentary amenities and fitness.
The price is $59
$59
$65 total
includes taxes & fees
Jan 12 - Jan 13
Big River Escape Riverside Cabins
Big River Escape Riverside Cabins
3.0 star property
Cochrane
9.2 out of 10, Wonderful, (41)
9.2/10
Wonderful
(41)
- Unwind in riverside cabins with kitchen convenience, just minutes from Mississippi River.
The price is $118
$118
$124 total
includes taxes & fees
Jan 28 - Jan 29
The Wen Inn formerly Andor Wenneson
The Wen Inn formerly Andor Wenneson
2.0 star property
Peterson
9.8 out of 10, Exceptional, (57)
9.8/10
Exceptional
(57)
- Escape to a charming inn adjacent to Peterson's golf course, with hiking trails nearby.
The price is $98
$98
$107 total
includes taxes & fees
Jan 18 - Jan 19
Stone Mill Hotel & Suites
Stone Mill Hotel & Suites
3.0 star property
Lanesboro
9.2 out of 10, Wonderful, (663)
9.2/10
Wonderful
(663)
- Experience the serenity of countryside living at this golf-adjacent retreat in Lanesboro.
The price is $105
$105
$113 total
includes taxes & fees
Jan 5 - Jan 6
Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1002)
8.8/10
Excellent
(1002)
- Modern rooms near Mayo Clinic with indoor pool and free hot breakfast daily.
The price is $73
$73
$84 total
includes taxes & fees
Jan 11 - Jan 12
Spark by Hilton Rochester South
Spark by Hilton Rochester South
3.0 star property
Rochester
9.2 out of 10, Wonderful, (337)
9.2/10
Wonderful
(337)
- Cozy lodging near Mayo Clinic with complimentary breakfast and indoor pool access.
The price is $71
$71
$81 total
includes taxes & fees
Jan 11 - Jan 12
Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1003)
9.0/10
Wonderful
(1003)
- Peaceful hotel near Mayo Clinic with indoor pool and daily complimentary breakfast.
The price is $81
$81
$93 total
includes taxes & fees
Jan 24 - Jan 25
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (897)
8.8/10
Excellent
(897)
- Relax in quiet comfort with Mayo Clinic just a 15-minute walk away from this hotel.
The price is $80
$80
$92 total
includes taxes & fees
Jan 24 - Jan 25
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.2 out of 10, Good, (1032)
7.2/10
Good
(1032)
- Convenient location near Mayo Clinic with free daily breakfast and on-site fitness.
The price is $72
$72
$83 total
includes taxes & fees
Jan 6 - Jan 7
Quality Inn & Suites Mayo Clinic Area
Quality Inn & Suites Mayo Clinic Area
2.5 star property
Rochester
8.8 out of 10, Excellent, (836)
8.8/10
Excellent
(836)
- Quiet refuge in Rochester's medical district with free hot breakfast daily.
The price is $65
$65
$76 total
includes taxes & fees
Feb 1 - Feb 2
Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (909)
9.0/10
Wonderful
(909)
- Restful retreat near Mayo Clinic with 24-hour fitness center and complimentary perks.
The price is $68
$68
$78 total
includes taxes & fees
Jan 30 - Jan 31
Hilton Garden Inn Rochester Downtown, MN
Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester
8.8 out of 10, Excellent, (858)
8.8/10
Excellent
(858)
- A welcoming downtown haven near Mayo Clinic with indoor pool and hot tub.
The price is $107
$107
$123 total
includes taxes & fees
Jan 11 - Jan 12
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very Good, (1158)
8.2/10
Very Good
(1158)
- Peaceful retreat near Mayo Clinic with serene atmosphere and indoor pool.
The price is $77
$77
$89 total
includes taxes & fees
Jan 7 - Jan 8
Country Inn & Suites Rochester South Mayo Clinic
Country Inn & Suites Rochester South Mayo Clinic
3.0 star property
Rochester
8.4 out of 10, Very Good, (1002)
8.4/10
Very Good
(1002)
- A peaceful Mayo Clinic escape with complimentary hot breakfast and tranquil pool area.
The price is $89
$89
$103 total
includes taxes & fees
Jan 11 - Jan 12
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (1014)
9.2/10
Wonderful
(1014)
- Stay near Mayo Clinic with comfort amenities and complimentary breakfast.
The price is $137
$137
$158 total
includes taxes & fees
Jan 24 - Jan 25
Hilton Rochester Mayo Clinic Area
Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (548)
9.6/10
Exceptional
(548)
- Convenient downtown retreat for Mayo Clinic patients with spa and dining options.
The price is $171
$171
$197 total
includes taxes & fees
Jan 10 - Jan 11
Kahler Grand Hotel
Kahler Grand Hotel
3.0 star property
Downtown Rochester
8.4 out of 10, Very Good, (1851)
8.4/10
Very Good
(1851)
- Quiet historic escape with indoor pool, minutes from Mayo Clinic facilities.
The price is $149
$149
$172 total
includes taxes & fees
Jan 7 - Jan 8
Super 8 by Wyndham Rochester Mayo Clinic Area
Super 8 by Wyndham Rochester Mayo Clinic Area
2.0 star property
Rochester
7.8 out of 10, Good, (1002)
7.8/10
Good
(1002)
- Peaceful retreat near Mayo Clinic with free WiFi, parking, and breakfast daily.
The price is $54
$54
$63 total
includes taxes & fees
Jan 15 - Jan 16
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in St. Charles
Pet friendly
Family friendly
Learn more about St. Charles
St. Charles is well-known for its attractions such as Whitewater State Park and Whitewater River.
Check out reviews of St. Charles hotels guests love
Express Suites Riverport Inn & Suites
10/10 Excellent
"Great stay"
Kahler Grand Hotel
10/10 Excellent
"Clean, comfortable room. The staff was very helpful"
Spark by Hilton Rochester South
10/10 Excellent
"Nice place to stay. No hot breakfast though only Complimentary breakfast offered. "
Hotel Indigo Rochester – Mayo Clinic Area by IHG
10/10 Excellent
"The hotel was clean and a friendly staff at check in. We love that the hotel skyway is connected to Mayo, so could walk to appts. inside on a cold day. We also appreciated a noon check out."
Brentwood Inn & Suites
10/10 Excellent
"LOVE this hotel. We stay every time we go to Mayo. It is out dated but SUPER CLEAN, a place you can tell employees take pride in. We always recognize staff even through the years. Everyone is always helpful and kind. Great breakfast as well. One huge perk too is it has access in the hotel to the subway system. Thanks Brentwood for another awesome stay, you never disappoint. "
The Berkman
10/10 Excellent
"It was a bit tricky finding our area we could park in but it worked out. "
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
10/10 Excellent
"Friendly staff and very clean "
EVEN Hotel Rochester - Mayo Clinic Area by IHG
10/10 Excellent
"The staff was very friendly and the room spotless. "
Kahler Inn and Suites - Mayo Clinic Area
10/10 Excellent
"Great service. Clean room. Good breakfast"
Frequently asked questions
What accommodations do travelers recommend in St. Charles?
White Valley Motel is an accommodation that is popular with guests.
Can I book refundable accommodations in St. Charles?
If you need the flexibility to change your plans to St. Charles, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in St. Charles be like during my vacation?
July and August are typically the warmest months in St. Charles when the average temp is 67°F. January and February are the coldest months when the average temperature is 22°F. June and May are the months with the most rain.
Why should I book my St. Charles accommodation with Hotels.com?
There are plenty of reasons to book your St. Charles travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.