Hotels in St. Charles

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White Valley Motel
White Valley Motel
2.5 star property
St. Charles
5.6 out of 10, (129 reviews)
  • cleanliness
    Cozy riverside motel in St. Charles with easy access to Whitewater River.
The price is $69
$77 total
includes taxes & fees
Apr 1 - Apr 2
White Valley Motel
Big River Escape Grandview Manse
Big River Escape Grandview Manse
3.0 star property
Altura
10.0 out of 10, Exceptional, (4 reviews)
  • cleanliness
    Charming vacation home in Altura with kitchen amenities and natural surroundings.
The price is $370
$397 total
includes taxes & fees
Apr 1 - Apr 2
Big River Escape Grandview Manse
Days Inn by Wyndham Winona
Days Inn by Wyndham Winona
2.0 star property
Winona
7.8 out of 10, Good, (1,000 reviews)
  • cleanliness
    Modern Days Inn by the Mississippi with complimentary amenities and fitness.
The price is $68
$76 total
includes taxes & fees
Apr 2 - Apr 3
Days Inn by Wyndham Winona
The Wen Inn formerly Andor Wenneson
The Wen Inn formerly Andor Wenneson
2.0 star property
Peterson
9.8 out of 10, Exceptional, (62 reviews)
  • cleanliness
    Escape to a charming inn adjacent to Peterson's golf course, with hiking trails nearby.
The price is $87
$96 total
includes taxes & fees
Apr 14 - Apr 15
The Wen Inn formerly Andor Wenneson
Big River Escape Riverside Cabins
Big River Escape Riverside Cabins
3.0 star property
Cochrane
9.2 out of 10, Wonderful, (44 reviews)
  • cleanliness
    Unwind in riverside cabins with kitchen convenience, just minutes from Mississippi River.
The price is $98
$104 total
includes taxes & fees
Apr 2 - Apr 3
Big River Escape Riverside Cabins
AmericInn by Wyndham Winona
AmericInn by Wyndham Winona
2.5 star property
Winona
9.2 out of 10, Wonderful, (920 reviews)
  • cleanliness
    Stay minutes from Winona State University with hot tub and complimentary perks.
The price is $116
$130 total
includes taxes & fees
Apr 12 - Apr 13
AmericInn by Wyndham Winona
Stone Mill Hotel & Suites
Stone Mill Hotel & Suites
3.0 star property
Lanesboro
9.2 out of 10, Wonderful, (669 reviews)
  • cleanliness
    Experience the serenity of countryside living at this golf-adjacent retreat in Lanesboro.
The price is $105
$113 total
includes taxes & fees
Apr 1 - Apr 2
Stone Mill Hotel & Suites
Green Gables Inn
Green Gables Inn
2.0 star property
Lanesboro
9.6 out of 10, Exceptional, (73 reviews)
  • cleanliness
    Explore the charm of Lanesboro with a quaint inn near Root River and local parks.
The price is $102
$109 total
includes taxes & fees
Apr 1 - Apr 2
Green Gables Inn
The Rushford Inn
The Rushford Inn
3.0 star property
Rushford
The price is $159
$176 total
includes taxes & fees
Apr 1 - Apr 2
The Rushford Inn
Spark by Hilton Rochester South
Spark by Hilton Rochester South
3.0 star property
Rochester
9.4 out of 10, Exceptional, (421 reviews)
  • cleanliness
    Cozy lodging near Mayo Clinic with complimentary breakfast and indoor pool access.
The price is $73
$84 total
includes taxes & fees
Apr 12 - Apr 13
Spark by Hilton Rochester South
Big River Escape Parkside Bungalow
Big River Escape Parkside Bungalow
3.0 star property
Winona
10.0 out of 10, Exceptional, (1 review)
  • cleanliness
    Quiet cottage retreat near Winona Station with free WiFi and parking.
The price is $206
$230 total
includes taxes & fees
Apr 5 - Apr 6
Big River Escape Parkside Bungalow
Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,006 reviews)
  • cleanliness
    Modern rooms near Mayo Clinic with indoor pool and free hot breakfast daily.
The price is $99
$114 total
includes taxes & fees
Apr 5 - Apr 6
Holiday Inn Express Rochester South - Mayo Area by IHG
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.2 out of 10, Good, (1,032 reviews)
  • cleanliness
    Convenient location near Mayo Clinic with free daily breakfast and on-site fitness.
The price is $72
$83 total
includes taxes & fees
Apr 1 - Apr 2
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.0 out of 10, Very Good, (1,244 reviews)
  • cleanliness
    Peaceful retreat near Mayo Clinic with serene atmosphere and indoor pool.
The price is $73
$84 total
includes taxes & fees
Apr 5 - Apr 6
AmericInn by Wyndham Rochester Near Mayo Clinic
Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (955 reviews)
  • cleanliness
    Restful retreat near Mayo Clinic with 24-hour fitness center and complimentary perks.
The price is $68
$78 total
includes taxes & fees
Apr 19 - Apr 20
Econo Lodge Mayo Clinic Area
Carriage House B&B
Carriage House B&B
3.0 star property
Historic Downtown Winona
9.6 out of 10, Exceptional, (89 reviews)
  • cleanliness
    Experience Victorian elegance in Winona, with easy access to hiking trails.
The price is $148
$165 total
includes taxes & fees
Apr 1 - Apr 2
Carriage House B&B
Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,009 reviews)
  • cleanliness
    Peaceful hotel near Mayo Clinic with indoor pool and daily complimentary breakfast.
The price is $86
$99 total
includes taxes & fees
Apr 26 - Apr 27
Hampton Inn Rochester-South
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (971 reviews)
  • cleanliness
    Relax in quiet comfort with Mayo Clinic just a 15-minute walk away from this hotel.
The price is $93
$107 total
includes taxes & fees
Apr 4 - Apr 5
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Baymont by Wyndham Rochester Mayo Clinic Area
Baymont by Wyndham Rochester Mayo Clinic Area
2.5 star property
Rochester
7.0 out of 10, Good, (756 reviews)
The price is $60
$69 total
includes taxes & fees
Apr 6 - Apr 7
Baymont by Wyndham Rochester Mayo Clinic Area
Birch Hill Suite Rochester – Med City
Birch Hill Suite Rochester – Med City
2.5 star property
Rochester
7.8 out of 10, Good, (25 reviews)
  • cleanliness
    Stylish retreat close to Mayo Clinic with thoughtful traveler amenities.
The price is $59
$68 total
includes taxes & fees
Apr 5 - Apr 6
Birch Hill Suite Rochester – Med City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

St. Charles is well-known for its attractions such as Whitewater State Park and Whitewater River.

St. Charles is a rural Community in South East Minnesota

Check out reviews of St. Charles hotels guests love

Frequently asked questions

What accommodations do travelers recommend in St. Charles?
White Valley Motel is an accommodation that is popular with guests.
Can I book refundable accommodations in St. Charles?
If you need the flexibility to change your plans to St. Charles, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in St. Charles be like during my vacation?
July and August are typically the warmest months in St. Charles when the average temp is 67°F. January and February are the coldest months when the average temperature is 22°F. June and May are the months with the most rain.
Why should I book my St. Charles accommodation with Hotels.com?
There are plenty of reasons to book your St. Charles travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.