Hotels in Greenville

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Check prices for these dates

Tonight
Sep 4 - Sep 5
Tomorrow
Sep 5 - Sep 6
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Where to stay in Greenville?

A hotel room with a bed, bedside tables, a desk, a chair, a TV, and a window with curtains.
A covered outdoor area with a concrete walkway, large windows, and a building with a gray exterior.
A reception desk with a wooden finish, a framed picture on the wall, a clock, and a chair in the room.
A hotel lobby with a wooden reception desk, a round table, a clock, and a coat rack.

Budget Inn Motel

Budget Inn Motel
Greenville
$48
$54 total
includes taxes & fees
Sep 5 - Sep 6
Budget Inn Motel
A modern living room with a fireplace, blue sofa, red chairs, and a flat-screen TV mounted on a textured wall.
A reception desk with a wooden panel design, a large 'C' logo, and a glass partition.
A hotel reception area with a computer desk, a printer, a coffee machine, and a framed cityscape picture on the wall.
A hotel reception area with a long wooden counter, coffee machines, and a wall with framed pictures.

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
Greenville
$98
$109 total
includes taxes & fees
Sep 20 - Sep 21
Comfort Inn & Suites Greenville I-70
A hotel room with a large bed, a desk, a chair, a TV, a mirror, and a bathroom with a bathtub and sink.
A restaurant with wooden tables and chairs, a kitchen area, and a vending machine.
A hotel lobby with a reception desk, a staircase to an upper level, a sofa, and a TV mounted on the wall.
A SureStay hotel entrance with a covered waiting area, brick facade, and potted plants.

SureStay Hotel by Best Western Greenville

SureStay Hotel by Best Western Greenville
Greenville
$61
$68 total
includes taxes & fees
Sep 28 - Sep 29
SureStay Hotel by Best Western Greenville
A hotel room with a bed, a television, a desk, and a chair.
A reception area with a reception desk, a computer, a sewing machine, and an exit sign.
A multi-story hotel with a covered entrance, a Super 8 logo, and a brick facade.
A breakfast area with a counter, microwave, coffee machine, and seating.

Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
Greenville
$71
$79 total
includes taxes & fees
Sep 10 - Sep 11
Super 8 by Wyndham Greenville
A hotel room with a blue sofa, a bed with white bedding, a nightstand, a desk with a chair, and a large window offering a view.
A hotel room with a bed, bedside table, chair, and artwork on the walls.
An indoor swimming pool with tiled flooring, a metal ladder, and seating areas with chairs and tables.
A modern hotel lobby with a reception desk, seating area, and a large wall mural.

Holiday Inn Express & Suites Vandalia by IHG

Holiday Inn Express & Suites Vandalia by IHG
Vandalia
$114
$124 total
includes taxes & fees
Sep 7 - Sep 8
Holiday Inn Express & Suites Vandalia by IHG
A neatly made bed with a patterned bedspread, a framed picture above it, a chair, a lamp, and a checkered floor.
Two double beds with patterned headboards, a bedside table with a lamp, and framed pictures on the wall.
A motel with a prominent 'MOTEL' sign.
A room with teal walls, a wooden desk, a chair, a television, a lamp, a microwave, and a coat rack.

Powhatan Motel

Powhatan Motel
Pocahontas
$97
$103 total
includes taxes & fees
Sep 5 - Sep 6
Powhatan Motel
A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.
A hotel room with a sofa, two lamps, a television, and a desk.
A hotel room with a wooden dining table, four brown chairs, a beige sofa, a small wooden coffee table, a lamp, a framed picture on the wall, and a kitchenette with a microwave.
A kitchen with a dishwasher, coffee makers, a water dispenser, and various kitchen utensils.

Seasons Inn & Suites Highland

Seasons Inn & Suites Highland
Highland
$94
$104 total
includes taxes & fees
Sep 6 - Sep 7
Seasons Inn & Suites Highland
A lobby with a wooden staircase, a desk with a computer, and patterned armchairs.
A kitchen with white cabinets, a microwave, a coffee machine, and a refrigerator.
A Ramada hotel with a brick facade, large entrance, and a clear sky.
A hotel room with a large bed, two bedside tables, a nightstand, and a lamp on each side.

Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
Vandalia
$84
$92 total
includes taxes & fees
Oct 4 - Oct 5
Ramada by Wyndham Vandalia
A white door with the number 16, a mailbox, and a small light fixture on the left.
A bathroom with a bathtub, toilet, and a shower curtain.
A compact bathroom with a white microwave, a sink with a dark faucet, and a red rug on the floor.
A hotel room with two beds, a desk, and a chair. There are framed pictures on the walls and a lamp on the desk.

Lighthouse Lodge

Lighthouse Lodge
Pocahontas
$74
$83 total
includes taxes & fees
Sep 5 - Sep 6
Lighthouse Lodge
An indoor swimming pool with a clear view of the sky through the roof, surrounded by red lounge chairs and a few tables.
A hotel room with a bed, a sofa, a small table, and a chair. There is a door and a lamp on a nightstand.
A spacious lobby with a seating area, a television, and a reception desk.
A Baymont by Wyndham hotel with a blue facade, a covered entrance, and a parking lot.

Baymont by Wyndham Litchfield

Baymont by Wyndham Litchfield
Litchfield
$93
$102 total
includes taxes & fees
Sep 5 - Sep 6
Baymont by Wyndham Litchfield
A hotel room with a bed, a desk with a chair, a sofa, and a small table.
A modern lobby with a stone accent wall, a flat-screen TV, orange armchairs, a dark sofa, and a colorful rug.
A hotel lobby with a reception desk, seating area, and a TV mounted on the wall.
A hotel reception area with a reception desk, a clock, a television, and a seating area with an orange chair and a table.

Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
Vandalia
$76
$83 total
includes taxes & fees
Oct 5 - Oct 6
Quality Inn & Suites Vandalia near I-70 and Hwy 51
A restaurant with a bar area, seating, and a view of the outside.
A sign for the Americas Best Value Inn with an entrance sign.
A hotel room with a bed, a desk, a chair, a table, a mirror, and a bathroom visible in the background.
A basic earth hair care kit with shampoo, conditioner, and body lotion tubes, and a box.

Americas Best Value Inn Vandalia

Americas Best Value Inn Vandalia
Vandalia
$60
$65 total
includes taxes & fees
Sep 6 - Sep 7
Americas Best Value Inn Vandalia
A modern living room with patterned carpet, two sofas, a coffee table, and a TV.
A modern kitchen with white cabinets, a black countertop, and a dining area with a table and chairs.
A hotel room with two beds, a cityscape mural, a lamp, and a patterned bedspread.
A hotel lobby with a reception desk, a chandelier, and a patterned carpet.

Super 8 by Wyndham Staunton

Super 8 by Wyndham Staunton
Staunton
$81
$90 total
includes taxes & fees
Sep 28 - Sep 29
Super 8 by Wyndham Staunton
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.
A hotel room with two beds, a large window with curtains, a wall-mounted lamp, and a patterned carpet.
A spacious lobby with a large seating area, a reception desk, and a television.
A modern kitchen with a checkered tile backsplash, wooden flooring, and stainless steel appliances.

Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
Centralia
$139
$156 total
includes taxes & fees
Sep 6 - Sep 7
Best Western Plus Centralia Hotel & Suites
A Holiday Inn Express & Suites building with a covered entrance and a landscaped area with plants and rocks.
An indoor swimming pool with a tiled edge, surrounded by green chairs and tables, and large windows with a view.
A modern hotel lobby with a seating area, a coffee shop, and a bar.
A gym with treadmills, stationary bikes, and elliptical machines.

Holiday Inn Express & Suites Litchfield West by IHG

Holiday Inn Express & Suites Litchfield West by IHG
Litchfield
$122
$134 total
includes taxes & fees
Oct 5 - Oct 6
Holiday Inn Express & Suites Litchfield West by IHG
A hotel room with a bed, a desk, a television, a chair, and a window with curtains.
A gym with various exercise equipment, a mirror, a sink, and a chair.
A reception area with a counter, a mounted television, a door, and a wall-mounted sign.
A spacious living room with a fireplace, a television, and a modern chandelier.

Quality Inn Litchfield Route 66

Quality Inn Litchfield Route 66
Litchfield
$68
$75 total
includes taxes & fees
Oct 1 - Oct 2
Quality Inn Litchfield Route 66
A Hampton Inn hotel with a flagpole, clear signage, and a well-maintained lawn.
A swimming pool with clear blue water, surrounded by chairs and a view of the outdoors.
A buffet area with cereal bowls, spoons, and a fruit bowl.
A hotel dining area with multiple tables and chairs, a bar, and a reception desk.

Hampton Inn by Hilton Litchfield

Hampton Inn by Hilton Litchfield
Litchfield
$102
$112 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn by Hilton Litchfield
An ice dispenser with a sign indicating it's for ice machines, a caution sign about not filling ice chests, and a plant in the foreground.
A reception desk with a large illuminated number 6, a clock above it, and various informational posters and signs around the area.
A blue sign with the number 6 and the word "hotel" on it.
A hotel room with a bed, desk, chair, lamp, TV, and a bathroom visible through an open door.

Motel 6 Litchfield, IL

Motel 6 Litchfield, IL
Litchfield
$75
$82 total
includes taxes & fees
Sep 5 - Sep 6
Motel 6 Litchfield, IL
A hotel room with a bed, a chair, a small table, a lamp, a television, and a window with curtains.
A compact laundry area with a front-loading washer and dryer, a small countertop with a scale, and a mirror above the dryer.
A hotel room with a wooden dresser, a television, a desk, a chair, and a refrigerator.
A hotel hallway with blue doors, a patterned carpet, and a light fixture on the wall.

Countryside Inn

Countryside Inn
Hillsboro
$79
$87 total
includes taxes & fees
Sep 5 - Sep 6
Countryside Inn
A riverside view with a gravel path and a building with a red facade.
A bathroom with a bathtub, a shower, and a curtain.
A motel with a gravel driveway, a river in the background, and a clear blue sky.
A hotel room with two beds, a small kitchenette, and a single nightstand with a lamp.

Innkeeper Motel

Innkeeper Motel
Hamel
$63
$70 total
includes taxes & fees
Sep 12 - Sep 13
Innkeeper Motel
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Our prices for hotels in Greenville are cheapest in December
Price trends for hotels in Greenville
Pricing is based on two traveler single night rates
View properties in September
Typical weather for Greenville
September
High 26°C / low 16°C. Sunny most days.
View properties in September
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29°
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Monthly weather averages (˚C)

Top landmarks in Greenville

Patriot's Park

8.4/10 (14 reviews)
Patriot's Park is 1.4 mi (2.2 km) from central Greenville, why not stop by during your stay.
See properties

Greenville Country Club

7.6/10 (14 reviews)
You might want to practice your swing at Greenville Country Club, a golf course located 2.2 mi (3.5 km) from central Greenville.
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Learn more about Greenville

Greenville is well-known for its attractions such as Patriot's Park and Greenville Country Club. Visitors speak highly of this family-friendly city's restaurants and small-town setting.

See all hotels in Greenville
A calm lake reflecting autumn trees with vibrant orange and yellow foliage.

Check out reviews of Greenville hotels guests love

Hampton Inn by Hilton Litchfield

Hampton Inn by Hilton Litchfield

10/10 Excellent
"Good room and breakfast"
Aimee 1-night trip
Posted 21 hours ago
Hampton Inn by Hilton Litchfield
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51

8/10 Good
"The room was clean except for the mirror and floor. I got out of the shower and wiped the floor with a towel and the towel was dirty.. Breakfast was the same thing both mornings, it was good. The pool is closed for the season already!"
Debbie 2-night trip
Posted 4 days ago
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Holiday Inn Express & Suites Vandalia by IHG

Holiday Inn Express & Suites Vandalia by IHG

10/10 Excellent
"Nice"
Len 1-night trip
Posted 4 days ago
Holiday Inn Express & Suites Vandalia by IHG
Budget Inn Motel

Budget Inn Motel

10/10 Excellent
"I was stinned at the quality of the rooms for the price Will definitely use again!"
Cynthia 1-night trip
Posted 1 month ago
Budget Inn Motel

Frequently asked questions

What accommodations do travelers recommend in Greenville?
Guests like Comfort Inn & Suites Greenville I-70, Super 8 by Wyndham Greenville and SureStay Hotel by Best Western Greenville.
Can I book refundable hotels in Greenville?
If you want the flexibility to change your plans to Greenville, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where should I stay in Greenville if I'm looking for a cheap accommodation?
Two inexpensive options worth considering are Comfort Inn & Suites Greenville I-70 and SureStay Hotel by Best Western Greenville.
Where can I stay in Greenville if I want a vacation home instead of a hotel?
If you want to find a good alternative to a hotel, look over our selection of 5 vacation homes.
What will the weather in Greenville be like during my vacation?
July and August are typically the warmest months in Greenville when the average temp is 74°F. January and February are the coldest months when the average temperature is 36°F. April and May are the months with the most rain.
Why should I book my Greenville hotel through Hotels.com?
There are lots of reasons to book your Greenville trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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