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Hotels in Cayce

October 2026
November 2026

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Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Where to stay in Cayce?

A modern bistro with a wooden counter, a menu board, and a refrigerated display.
A hotel room with two beds, a TV, a desk, and a large window with a view of trees.
A modern lobby with seating areas, a reception desk, and a large abstract painting on the wall.
A Courtyard Marriott hotel with a modern design, featuring multiple floors and a well-lit entrance.

1. Courtyard by Marriott Columbia Cayce

Courtyard by Marriott Columbia Cayce
Cayce
$127
$141 total
includes taxes & fees
Oct 4 - Oct 5
Courtyard by Marriott Columbia Cayce
A modern living room with a grey sofa, a wooden bookshelf, a large wall clock, a fireplace, and a staircase.
A multi-story hotel with a modern design, featuring a covered entrance and a parking lot.
A modern kitchen with blue cabinets, a coffee station, and a microwave.

2. Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC
Cayce
$95
$106 total
includes taxes & fees
Oct 18 - Oct 19
Country Inn & Suites by Radisson, Columbia Airport, SC

3. Econo Lodge Inn & Suites Cayce I-26 Airport

Econo Lodge Inn & Suites Cayce I-26 Airport
Cayce
$66
$77 total
includes taxes & fees
Oct 25 - Oct 26
Econo Lodge Inn & Suites Cayce I-26 Airport
A pool area with a picnic table, surrounded by various plants and trees.
A kitchenette with a refrigerator, coffee maker, and a sink.
A reception desk with a sign reading "Masters Inn." There is a decorative wreath above the sign, and a shelf with various items on the right side.
A motel with a green sign, a parking lot, and a building with multiple floors.

4. Masters Inn Columbia I-26

Masters Inn Columbia I-26
Cayce
$60
$67 total
includes taxes & fees
Sep 27 - Sep 28
Masters Inn Columbia I-26
A breakfast bar with a variety of food options, a coffee machine, and a seating area with a view.
A multi-story hotel with a flat roof, balconies, and a parking lot.
A hotel room with a bed, a nightstand, a desk, a chair, a bathroom with a bathtub, and a patterned curtain.
A vending machine with a tropical beach mural, an ice cube dispenser, and a Coca-Cola vending slot.

5. Quality Inn West Columbia - Cayce

Quality Inn West Columbia - Cayce
West Columbia
$68
$75 total
includes taxes & fees
Oct 18 - Oct 19
Quality Inn West Columbia - Cayce
A hotel dining area with wooden tables and chairs, a kitchen in the background, and a flat-screen TV on the wall.
A hotel room with a large bed, two bedside tables with lamps, a green accent wall, and framed pictures above the bed.
A living room with a sofa, two armchairs, a coffee table, and a rug. There are picture frames on the wall and two lamps on side tables.
A hotel room with a flat-screen TV, a desk with a lamp, a microwave, and a refrigerator.

6. Sleep Inn Columbia Airport

Sleep Inn Columbia Airport
West Columbia
$82
$95 total
includes taxes & fees
Oct 18 - Oct 19
Sleep Inn Columbia Airport
A modern hotel room with a large bed, bedside tables, a headboard with integrated lighting, a patterned curtain, and a door with a keycard lock.
A compact kitchen with a granite countertop, a stainless steel sink, and a built-in microwave.
A laundry facility with Whirlpool washers and dryers, a refrigerator, and a vending machine.
A room with two red chairs, a floor lamp, and a painting on the wall.

7. Studio 6 West Columbia, SC - Airport

Studio 6 West Columbia, SC - Airport
West Columbia
$66
$71 total
includes taxes & fees
Sep 27 - Sep 28
Studio 6 West Columbia, SC - Airport
A modern bar area with a long counter, multiple bar stools, and a decorative wall with geometric patterns.
A modern retail space with shelves stocked with beverages, snacks, and other items.
A multi-story hotel with a modern design, featuring a mix of brick and glass facades, and a prominent entrance with a covered walkway.
An outdoor patio with a bar area, seating, and a grill station.

8. Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown
Downtown Columbia
$118
$132 total
includes taxes & fees
Oct 18 - Oct 19
Tru By Hilton Columbia Downtown
A modern hotel building with a prominent 'tru by Hilton' sign, multiple floors, and a well-lit entrance.
A modern cafe with a central display of snacks and beverages, a seating area with sofas, and a ceiling with unique lighting fixtures.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with a blue sofa, hanging chairs, and a table with chairs.

9. Tru By Hilton Columbia Greystone

Tru By Hilton Columbia Greystone
Columbia
$98
$111 total
includes taxes & fees
Oct 18 - Oct 19
Tru By Hilton Columbia Greystone
A modern hotel room with a large bed, a seating area, and a TV.
A pool table with balls, a bar area, and a large TV screen.
A multi-story hotel with a modern design, featuring a prominent vertical stripe pattern on the facade.
A modern kitchen with a central island, wooden cabinets, a built-in washer and dryer, and a view of the city.

10. Homewood Suites By Hilton Columbia Downtown

Homewood Suites By Hilton Columbia Downtown
Downtown Columbia
$126
$141 total
includes taxes & fees
Oct 4 - Oct 5
Homewood Suites By Hilton Columbia Downtown
A patio area with wicker furniture, a central fire pit, and outdoor umbrellas.
A spacious lobby with a fireplace, comfortable seating, and a large window offering a view.
A modern kitchen with a central island, bar stools, and a coffee station with various containers.
A spacious lobby with a large seating area, a coffee table, and a potted plant.

11. Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport
West Columbia
$114
$123 total
includes taxes & fees
Oct 11 - Oct 12
Hilton Garden Inn Columbia Airport
A modern interior with a reception desk, a bench, and a wall with a bulletin board.
A gym with treadmills, weight benches, dumbbells, and a large motivational mural.
A modern laundry room with a table, chairs, and washing machines.
A hotel room with two beds, a desk, a chair, and a bathroom visible through an open door.

12. LivSmart Studios by Hilton Columbia Greystone

LivSmart Studios by Hilton Columbia Greystone
Columbia
$114
$130 total
includes taxes & fees
Oct 11 - Oct 12
LivSmart Studios by Hilton Columbia Greystone
A modern bar area with a central island, bar stools, and a television.
A spacious lobby with a reception desk, seating area, and large windows allowing natural light.
A modern hotel room with a sectional sofa, a small table, and a TV mounted on the wall.
A modern dining area with marble tables and cushioned chairs, a central chandelier, and large windows providing natural light.

13. Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista
Downtown Columbia
$123
$138 total
includes taxes & fees
Oct 18 - Oct 19
Cambria Hotel Columbia Downtown The Vista
An outdoor patio area with brick walls, a covered seating area, and a fire pit.
A hotel room with two beds, a desk, a chair, a lamp, and artwork on the wall.
A modern breakfast area with a long counter, two hanging pendant lights, and a view of the outdoors through large windows.
A modern bar area with a high ceiling, bar stools, and a central bar counter.

14. Hampton Inn Columbia-Downtown Historic District

Hampton Inn Columbia-Downtown Historic District
Downtown Columbia
$122
$137 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn Columbia-Downtown Historic District
A hotel room with a large bed, a flat-screen TV mounted on the wall, a desk with a chair, a microwave, and a refrigerator.
A motel with a gas station, multiple floors, and a parking lot.
A modern kitchen area with a coffee machine, a refrigerator, and a window with blinds.
A parking garage with a Pepsi dispenser and an ICE dispenser.

15. Red Roof Inn Columbia, SC Airport

Red Roof Inn Columbia, SC Airport
West Columbia
$80
$86 total
includes taxes & fees
Sep 27 - Sep 28
Red Roof Inn Columbia, SC Airport
A modern kitchen with wooden cabinetry, a dining table with chairs, a microwave, and a blackboard on the wall.
A self-service food display with various snacks, beverages, and prepared dishes.
A modern hotel lobby with a seating area, a wooden reception desk, and a large wall art piece.
A multi-story hotel with a covered entrance and a brick facade.

16. Hyatt Place Columbia/Downtown/The Vista

Hyatt Place Columbia/Downtown/The Vista
Downtown Columbia
$135
$151 total
includes taxes & fees
Oct 6 - Oct 7
Hyatt Place Columbia/Downtown/The Vista
A hotel room with a bed, a desk with a computer, a nightstand, a lamp, and a window with curtains.
A modern living room with a brown sectional sofa, a white coffee table, and a kitchen area with stainless steel appliances.
A compact kitchen with a dishwasher, a refrigerator, and a coffee maker.

17. Residence Inn Columbia West/Lexington

Residence Inn Columbia West/Lexington
West Columbia
$137
$148 total
includes taxes & fees
Oct 4 - Oct 5
Residence Inn Columbia West/Lexington
A modern restaurant with a bar area, wooden stools, and a curved seating arrangement.
A modern hotel with a brick facade, large windows, and a covered entrance area.
A hotel room with a desk, two beds, a TV, and a large mirror.
A spacious lobby with a central seating area, a reception desk, and a modern ceiling design.

18. SpringHill Suites by Marriott Columbia Downtown/The Vista

SpringHill Suites by Marriott Columbia Downtown/The Vista
Downtown Columbia
$135
$154 total
includes taxes & fees
Oct 4 - Oct 5
SpringHill Suites by Marriott Columbia Downtown/The Vista
A hotel room with a large bed, two bedside tables, a nightstand, a wall-mounted lamp, and a window with curtains.
A modern kitchen area with a built-in microwave, a refrigerator, and a coffee machine.
A bathroom with a large mirror, a sink, and a framed picture on the wall.
A reception desk with a black counter, a glass partition, and a view of the city through the glass. There are chairs, a small plant, and a bulletin board with notices.

19. Gallus Stadium Park Inn, an Ascend Collection Hotel

Gallus Stadium Park Inn, an Ascend Collection Hotel
Downtown Columbia
$68
$76 total
includes taxes & fees
Oct 5 - Oct 6
Gallus Stadium Park Inn, an Ascend Collection Hotel
A modern dining area with a central island, multiple seating options, and pendant lighting.
A patio area with outdoor furniture, a pergola, and a brick building in the background.
A hotel with a modern facade, a well-lit entrance, and an American flag.
A reception desk with a wooden finish and a modern design, featuring a large circular artwork on the wall behind it.

20. Fairfield Inn & Suites by Marriott Columbia Downtown

Fairfield Inn & Suites by Marriott Columbia Downtown
Downtown Columbia
$98
$110 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield Inn & Suites by Marriott Columbia Downtown
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Go beyond your typical stay in Cayce

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Our prices for hotels in Cayce are cheapest in January

Price trends for hotels in Cayce

Pricing is based on two traveler single night rates
View properties in September

September

High 30°C / low 20°C. Sunny most days.
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Monthly weather averages (˚C)

Top landmarks in Cayce

Congaree Creek Heritage Preserve

9.4/10 (9 reviews)
Congaree Creek Heritage Preserve is 1.3 mi (2.1 km) from central Cayce, why not stop by during your stay. Want to stretch your legs some more? Head to West Columbia Riverwalk and Finlay Park, both nearby.
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Cayce Historical Museum

8.8/10 (5 reviews)
Cayce Historical Museum is 1 mi (1.6 km) from central Cayce, why not stop by during your stay. If you want to experience more of the culture Cayce has to offer, head to West Columbia Riverwalk, South Carolina State Museum, and EdVenture Children's Museum.
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Learn more about Cayce

Cayce is well-known for its attractions such as Congaree Creek Heritage Preserve and Cayce Historical Museum. The city has something for everyone including restaurants along with sights like Bowlero Cayce and Three Rivers Greenway.

See all hotels in Cayce
A cityscape at dusk with illuminated buildings, a prominent dome structure, and a well-lit street.

Check out reviews of Cayce hotels guests love

A modern living room with a blue cabinet, a blue sofa, a round coffee table, and patterned ottomans.
A hotel lobby with a modern chandelier, a reception desk, and a staircase with decorative railings.
A hotel room with exposed brick walls, a large bed, a desk with a telephone, and a television on the wall.
Two people celebrating with confetti in a bar setting.

Hotel Trundle

Hotel Trundle
Downtown Columbia

10/10 Exceptional

United States
Loretta
Hotel Trundle
A modern hotel room with a large bed, a seating area, and a TV.
A pool table with balls, a bar area, and a large TV screen.
A multi-story hotel with a modern design, featuring a prominent vertical stripe pattern on the facade.
A modern kitchen with a central island, wooden cabinets, a built-in washer and dryer, and a view of the city.

Homewood Suites By Hilton Columbia Downtown

Homewood Suites By Hilton Columbia Downtown
Downtown Columbia

10/10 Exceptional

United States
Takyra
Homewood Suites By Hilton Columbia Downtown
A modern bar area with a central island, bar stools, and a television.
A spacious lobby with a reception desk, seating area, and large windows allowing natural light.
A modern hotel room with a sectional sofa, a small table, and a TV mounted on the wall.
A modern dining area with marble tables and cushioned chairs, a central chandelier, and large windows providing natural light.

Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista
Downtown Columbia

10/10 Exceptional

United States
Carla
Cambria Hotel Columbia Downtown The Vista
A modern bistro with a wooden counter, a menu board, and a refrigerated display.
A hotel room with two beds, a TV, a desk, and a large window with a view of trees.
A modern lobby with seating areas, a reception desk, and a large abstract painting on the wall.
A Courtyard Marriott hotel with a modern design, featuring multiple floors and a well-lit entrance.

Courtyard by Marriott Columbia Cayce

Courtyard by Marriott Columbia Cayce
Cayce

10/10 Exceptional

United States
amy
Courtyard by Marriott Columbia Cayce
A modern room with large windows, a green armchair, a brown chair, a small round table, and a potted plant.
A modern hotel entrance with a green sign, outdoor seating, and planters.
A hotel room with a large bed, a desk with a TV, and a view of buildings through the windows.
A modern bar area with a sign reading "TOAST ORDER HERE," bar stools, a counter with a laptop, and a display of liquor bottles.

Holiday Inn Columbia - Downtown by IHG

Holiday Inn Columbia - Downtown by IHG
Downtown Columbia

10/10 Exceptional

United States
Fatmah
Holiday Inn Columbia - Downtown by IHG
A panoramic mosaic mural of a cityscape with buildings and greenery.
A modern hotel with a prominent 'La Quinta' sign, large windows, and a covered entrance area.
A hotel room with two beds, a nightstand with a phone and lamp, and two large landscape paintings on the wall.
A hotel lobby with a reception desk, a large cityscape mural, and a door leading to a parking area.

La Quinta Inn by Wyndham Columbia NE/Fort Jackson

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
Columbia

10/10 Exceptional

United States
Hugh
La Quinta Inn by Wyndham Columbia NE/Fort Jackson
A modern hotel room with a kitchenette, a large mirror, a bed, and a desk area.
A modern hotel lobby with a large wooden number '2' sign, a geometric patterned wall, and a blue accent in the reception desk area.
A modern hotel lobby with a central seating area, multiple tables, and a reception desk.
A modern kitchen with a built-in microwave, stainless steel appliances, a coffee maker, and a dish rack.

Home2 Suites by Hilton Blythewood, SC

Home2 Suites by Hilton Blythewood, SC
Blythewood

10/10 Exceptional

United States
Jerlin
Home2 Suites by Hilton Blythewood, SC
A spacious lobby with a high ceiling, a staircase, and a seating area with a patterned sofa and armchairs.
A hotel room with two beds, a desk, a TV, and a wardrobe.
A Holiday Inn Express building with a modern design, large windows, and a parking lot in front.
A coffee station with two espresso machines and a variety of coffee pods and cups.

Holiday Inn Express Columbia NE - Fort Jackson by IHG

Holiday Inn Express Columbia NE - Fort Jackson by IHG
Columbia

10/10 Exceptional

United States
Linda
Holiday Inn Express Columbia NE - Fort Jackson by IHG
A modern dining area with a central island, multiple seating options, and pendant lighting.
A patio area with outdoor furniture, a pergola, and a brick building in the background.
A hotel with a modern facade, a well-lit entrance, and an American flag.
A reception desk with a wooden finish and a modern design, featuring a large circular artwork on the wall behind it.

Fairfield Inn & Suites by Marriott Columbia Downtown

Fairfield Inn & Suites by Marriott Columbia Downtown
Downtown Columbia

10/10 Exceptional

United States
Eunice
Fairfield Inn & Suites by Marriott Columbia Downtown
An outdoor seating area with a fire feature, a wooden bench, and a modern design.
A MainStay Marketplace with shelves stocked with snacks and beverages, a small plant, and a logo on the wall.
A hotel room with a large bed, a desk with a chair, a small armchair, and a nightstand with a lamp.
A row of townhouses with a green lawn, a sidewalk, and a street.

Quality Inn & Suites Columbia Harbison

Quality Inn & Suites Columbia Harbison
Columbia

10/10 Exceptional

United States
Keith
Quality Inn & Suites Columbia Harbison
A modern kitchen with a long counter, a coffee machine, and a refrigerator.
A reception area with a cityscape mural, two reception desks, and a modern design.
A hotel named La Quinta with a modern architectural design, featuring a prominent sun logo and multiple windows.
A modern living room with a flat-screen TV mounted on a textured wall, two sofas with decorative pillows, a patterned rug, and two side tables with plants.

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Columbia

10/10 Exceptional

United States
Rosa
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
A hotel room with a sofa, a small table, a bed, and a painting on the wall.
A modern hotel lobby with seating, a coffee station, and a dining area.
A gym with treadmills, elliptical machines, and stationary bikes.
A lobby with a reception desk, two armchairs, a television, and a Coca-Cola vending machine.

Best Western Executive Inn & Suites

Best Western Executive Inn & Suites
Seven Oaks

10/10 Exceptional

United States
Jeffrey
Best Western Executive Inn & Suites
A modern hotel with a flat roof, a central entrance, and a parking lot in front.
A laundry facility with multiple washing machines and dryers, a blue wall, and a wooden floor.
A compact room with a bed, a desk with a TV, a kitchenette, and a dining area.
A reception desk with a blue wall and a leaf-shaped artwork above it.

Woodspring Suites Columbia - Irmo

Woodspring Suites Columbia - Irmo
Irmo

10/10 Exceptional

United States
Katelyn
Woodspring Suites Columbia - Irmo

Frequently Asked Questions

What accommodations do travelers like in Cayce?

Guests like Country Inn & Suites by Radisson, Columbia Airport, SC, Econo Lodge Inn & Suites Cayce I-26 Airport and Courtyard by Marriott Columbia Cayce.

Can I book refundable accommodations in Cayce?

If you want the flexibility to change your plans to Cayce, most properties offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where should I consider staying in Cayce if I want an affordable accommodation?

Country Inn & Suites by Radisson, Columbia Airport, SC is an accommodation you might want to consider that'll save you money.

Where can I stay in Cayce if I want a vacation home instead of a traditional hotel?

If you're looking for a good alternative to a hotel, review our selection of 19 vacation homes. In addition, you can choose from 5 apartments.

What will the weather in Cayce be like during my vacation?

July and August are typically the warmest months in Cayce when the average temp is 79°F. January and February are the coldest months when the average temperature is 50°F. August and July are the months with the most rain.

Why should I book my Cayce accommodation with Hotels.com?

There are lots of reasons to book your Cayce trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.