A cityscape at dusk with illuminated buildings, a prominent dome structure, and a well-lit street.

Hotels in Cayce

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A modern bistro with a wooden counter, a menu board, and a refrigerated display.

A modern lobby with seating areas, a reception desk, and a large abstract painting on the wall.

A hotel room with two beds, a TV, a desk, and a large window with a view of trees.

A Courtyard Marriott hotel with a modern design, featuring multiple floors and a well-lit entrance.

1. Courtyard by Marriott Columbia Cayce

Cayce

$127

$141 total

includes taxes & fees

Oct 11 - Oct 12

A modern living room with a grey sofa, a wooden bookshelf, a large wall clock, a fireplace, and a staircase.

A modern kitchen with blue cabinets, a coffee station, and a microwave.

A multi-story hotel with a modern design, featuring a covered entrance and a parking lot.

2. Country Inn & Suites by Radisson, Columbia Airport, SC

Cayce

$96

$107 total

includes taxes & fees

Nov 1 - Nov 2

3. Econo Lodge Inn & Suites Cayce I-26 Airport

Cayce

$66

$76 total

includes taxes & fees

Nov 1 - Nov 2

A pool area with a picnic table, surrounded by various plants and trees.

A red sofa, a yellow armchair, and a wooden coffee table with a potted plant in a hotel lobby.

A reception desk with a sign reading "Masters Inn." There is a decorative wreath above the sign, and a shelf with various items on the right side.

A kitchenette with a refrigerator, coffee maker, and a sink.

4. Masters Inn Columbia I-26

Cayce

$55

$61 total

includes taxes & fees

Nov 1 - Nov 2

A hotel dining area with wooden tables and chairs, a kitchen in the background, and a flat-screen TV on the wall.

A hotel room with a large bed, two bedside tables with lamps, a green accent wall, and framed pictures above the bed.

A living room with a sofa, two armchairs, a coffee table, and a rug. There are picture frames on the wall and two lamps on side tables.

A hotel room with a flat-screen TV, a desk with a lamp, a microwave, and a refrigerator.

5. Sleep Inn Columbia Airport

West Columbia

$81

$95 total

includes taxes & fees

Nov 1 - Nov 2

A breakfast bar with a variety of food options, a coffee machine, and a seating area with a view.

A multi-story hotel with a flat roof, balconies, and a parking lot.

A hotel room with a bed, a nightstand, a desk, a chair, a bathroom with a bathtub, and a patterned curtain.

A vending machine with a tropical beach mural, an ice cube dispenser, and a Coca-Cola vending slot.

6. Quality Inn West Columbia - Cayce

West Columbia

$68

$75 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel room with a large bed, bedside tables, a nightstand, and a bathroom visible through an open door.

A clean, modern reception area with a coffee machine, a digital screen, and decorative flowers.

A reception area with a large number '6' on the wall, a flower vase, and a counter with a black and white design.

A laundry room with two white washing machines, a large stainless steel dryer, and a door leading to another room.

7. Motel 6 West Columbia, SC - Airport

West Columbia

$67

$72 total

includes taxes & fees

Oct 5 - Oct 6

A modern bar area with a long counter, multiple bar stools, and a decorative wall with geometric patterns.

A multi-story hotel with a modern design, featuring a mix of brick and glass facades, and a prominent entrance with a covered walkway.

A modern lounge area with a sectional sofa, two armchairs, a coffee table, and a wall-mounted TV.

An outdoor patio with a bar area, seating, and a grill station.

8. Tru By Hilton Columbia Downtown

Downtown Columbia

$98

$109 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a large bed, two bedside tables, a nightstand, a wall-mounted lamp, and a window with curtains.

A reception desk with a black counter, a glass partition, and a view of the city through the glass. There are chairs, a small plant, and a bulletin board with notices.

A bathroom with a large mirror, a sink, and a framed picture on the wall.

A multi-story building with a modern architectural design, featuring a mix of stone and concrete facades, large windows, and a parking area with yellow curbs and red bollards.

9. Gallus Stadium Park Inn, an Ascend Collection Hotel

Downtown Columbia

$60

$68 total

includes taxes & fees

Oct 25 - Oct 26

A modern building entrance with a brick pathway leading to a glass door.

A snack display with various chips and packaged snacks.

A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

A gym with treadmills, stationary bikes, and weight machines.

10. Hampton Inn Columbia-I-26 Airport

West Columbia

$98

$108 total

includes taxes & fees

Oct 11 - Oct 12

A modern dining area with a central island, multiple seating options, and pendant lighting.

A reception desk with a wooden finish and a modern design, featuring a large circular artwork on the wall behind it.

A modern lounge area with a fireplace, comfortable seating, and a television.

A hotel with a modern facade, a well-lit entrance, and an American flag.

11. Fairfield Inn & Suites by Marriott Columbia Downtown

Downtown Columbia

$94

$105 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel room with a large bed, a seating area, and a TV.

A modern kitchen with a central island, wooden cabinets, a built-in washer and dryer, and a view of the city.

A multi-story hotel with a modern design, featuring a prominent vertical stripe pattern on the facade.

A pool table with balls, a bar area, and a large TV screen.

12. Homewood Suites By Hilton Columbia Downtown

Downtown Columbia

$126

$141 total

includes taxes & fees

Oct 18 - Oct 19

A modern restaurant with a bar area, wooden stools, and a curved seating arrangement.

A spacious lobby with a central seating area, a reception desk, and a modern ceiling design.

A modern kitchen with a wooden bar area, bar stools, and built-in appliances.

A modern hotel with a brick facade, large windows, and a covered entrance area.

13. SpringHill Suites by Marriott Columbia Downtown/The Vista

Downtown Columbia

$134

$153 total

includes taxes & fees

Oct 31 - Nov 1

A modern bar area with a central island, bar stools, and a television.

A spacious lobby with a reception desk, seating area, and large windows allowing natural light.

A modern hotel room with a sectional sofa, a small table, and a TV mounted on the wall.

A hotel room with two beds, a sofa, a desk, and a large window.

14. Cambria Hotel Columbia Downtown The Vista

Downtown Columbia

$127

$142 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel building with a prominent 'tru by Hilton' sign, multiple floors, and a well-lit entrance.

A modern cafe with a central display of snacks and beverages, a seating area with sofas, and a ceiling with unique lighting fixtures.

A breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

A modern lounge area with a blue sofa, hanging chairs, and a table with chairs.

15. Tru By Hilton Columbia Greystone

Columbia

$98

$112 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a sofa, a TV, a desk, and a window.

16. Hyatt Place Columbia/Downtown/The Vista

Downtown Columbia

$127

$142 total

includes taxes & fees

Oct 12 - Oct 13

A reception area with a stone mosaic wall, a wooden reception desk, and a counter with a green top. There are framed certificates on the wall and a vending machine to the right.

A hotel with a brick facade, a covered entrance, and a sign for Quality Inn.

A living room with a fireplace, two armchairs, a sofa, a flat-screen TV, and a ceiling-mounted air conditioning unit.

A hotel room with two beds, a green wall, and a blue curtain.

17. Quality Inn Columbia Airport

West Columbia

$59

$64 total

includes taxes & fees

Nov 1 - Nov 2

A rooftop bar with tables and chairs, overlooking a cityscape at dusk.

A historic building with ornate architectural details, a prominent entrance, and flags.

An outdoor seating area with wicker tables and chairs, a bar counter, and a ceiling fan.

A bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

18. Sheraton Columbia Downtown Hotel

Downtown Columbia

$114

$128 total

includes taxes & fees

Oct 22 - Oct 23

An outdoor seating area with a stone fireplace, a flat-screen TV mounted above it, and a view of the cityscape in the background.

A modern indoor space with a curved reception desk, a refrigerated display case with beverages, and a seating area with chairs and tables.

A modern bar area with a long counter, multiple bar stools, and a television screen above the bar.

A hotel room with two beds, a desk, and a chair.

19. Courtyard by Marriott Columbia Downtown at USC

Downtown Columbia

$127

$142 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor patio area with brick walls, a covered seating area, and a fire pit.

The Columbia Metropolitan Convention Center with a modern architectural design, featuring large windows and a prominent entrance.

A modern breakfast area with a long counter, two hanging pendant lights, and a view of the outdoors through large windows.

A hotel room with two beds, a desk, a chair, a lamp, and artwork on the wall.

20. Hampton Inn Columbia-Downtown Historic District

Downtown Columbia

$115

$129 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Go beyond your typical stay in Cayce

Our prices for hotels in Cayce are cheapest in January

Top landmarks in Cayce

Congaree Creek Heritage Preserve

9.4/10 (9 reviews)

Congaree Creek Heritage Preserve is 1.3 mi (2.1 km) from central Cayce, why not stop by during your stay. Want to stretch your legs some more? Head to West Columbia Riverwalk and Finlay Park, both nearby.

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Cayce Historical Museum

8.8/10 (5 reviews)

Cayce Historical Museum is 1 mi (1.6 km) from central Cayce, why not stop by during your stay. If you want to experience more of the culture Cayce has to offer, head to West Columbia Riverwalk, South Carolina State Museum, and EdVenture Children's Museum.

See properties

Learn more about Cayce

Cayce is well-known for its attractions such as Congaree Creek Heritage Preserve and Cayce Historical Museum. The city has something for everyone including restaurants along with sights like Bowlero Cayce and Three Rivers Greenway.

See all hotels in Cayce

Check out reviews of Cayce hotels guests love

Courtyard by Marriott Columbia Cayce

Cayce

10/10 Exceptional

amy

A spacious indoor area with a long table, multiple chairs, and a seating area with sofas and a TV.

A hotel room with a bed, a nightstand, a lamp, and a view of the outside.

A modern building with a brick facade, large windows, and outdoor exercise equipment.

A spacious lobby with modern furniture, a decorative partition, and a visible kitchen area.

The Lantern Hotel Columbia

Downtown Columbia

10/10 Exceptional

rhonda

A modern living room with a blue cabinet, a blue sofa, a round coffee table, and patterned ottomans.

Two people celebrating with confetti in a bar setting.

A hotel room with exposed brick walls, a large bed, a desk with a telephone, and a television on the wall.

A hotel lobby with a modern chandelier, a reception desk, and a staircase with decorative railings.

Hotel Trundle

Downtown Columbia

10/10 Exceptional

Loretta

Homewood Suites By Hilton Columbia Downtown

Downtown Columbia

10/10 Exceptional

Takyra

A two-story house with a porch, a small balcony, and a gabled roof.

A bedroom with a four-poster bed, a nightstand with a lamp, a wooden dresser, a chair, and a large window with curtains.

A spacious living area with a staircase, a dining area, and a hallway leading to another room.

The 1425 Inn

Downtown Columbia

10/10 Exceptional

I needed a place to stay close by to the hospital while my husband had surgery, but wanted a warm comfortable place. The place was just what I needed. Shanna was warm and welcoming, and couldn't have done more to make my stay a good one. I felt very much at home. The inn was beautifully decorated and well kept. Breakfast was excellent and there were snacks available at all times, a plus after a long day at the hospital. I would highly recommend this place.

Phoebe A

A modern hotel lobby with a large dining table, multiple seating areas, and a large screen wall.

A hotel room with a bed, desk, chair, air conditioning unit, and a window with a view of trees.

A snack and beverage kiosk with shelves stocked with various snacks and drinks, a chalkboard with writing, and a large circular sign with the word 'TREATS'.

A reception desk with a "Welcome to the Palmetto State" sign, a wooden accent wall, a minibar, and a digital kiosk.

Hampton Inn & Suites Lexington Columbia

Lexington

10/10 Exceptional

Jodi

Tru By Hilton Columbia Downtown

Downtown Columbia

10/10 Exceptional

Hynrie Emerlou

Cambria Hotel Columbia Downtown The Vista

Downtown Columbia

10/10 Exceptional

Carla

A two-story brick house with a porch, a flag, and a well-maintained lawn.

A traditional library with a fireplace, leather seating, and a patterned rug.

A bar area with a coffee machine, stools, and a menu board.

An outdoor patio area with brick buildings, tables, chairs, and umbrellas.

Graduate by Hilton Columbia SC

Downtown Columbia

10/10 Exceptional

Earl

An outdoor patio with a stone fire pit, seating, and a covered area with lights.

A modern reception area with a large digital display, a counter, and vending machines.

A hotel room with a modern design, featuring a large bed, a desk, and a seating area with a tray table.

A modern kitchen with dark wood cabinets, a white countertop, and various kitchen appliances.

Springhill Suites by Marriott Columbia near Fort Jackson

Columbia

10/10 Exceptional

Savannah

An outdoor patio with yellow chairs and tables, a pergola with string lights, and a stone wall.

A modern hotel with a flat facade, multiple windows, and a covered outdoor seating area.

A hotel room with a sofa, ottoman, table, and chairs. There is a bed in the adjacent room.

A swimming pool with a tiled edge, surrounded by yellow chairs and red umbrellas.

Home2 Suites by Hilton Columbia Southeast Fort Jackson

Columbia

10/10 Exceptional

Jodi

A hotel with a modern exterior, featuring a brick facade, large windows, and a well-lit outdoor area with palm trees and a landscaped garden.

A hotel reception area with a modern design, featuring a reception desk, a large abstract painting, and a unique ceiling structure.

A covered outdoor seating area with orange sofas and white tables, palm trees, and a view of a residential neighborhood.

A modern lobby with seating areas, a fireplace, and a large glass wall.

Holiday Inn Express & Suites Lexington by IHG

Downtown Lexington

10/10 Exceptional

Warning: I’ll be naming names in this review. To say that I was impressed is the understatement of the year! I am every hotels worst nightmare when it comes to my level of pickiness as a guest because I check everywhere. Well, this hotel beat me to the punch! Room 113 was so clean that we booked a second night just to extend our stay there. Sindy was responsible for cleaning my room so I found her and asked how she got it so clean. When she told me the entire cleaning staff uses black...

Jacqueline

Tru By Hilton Columbia Greystone

Columbia

10/10 Exceptional

Adam

A building entrance with a stone facade, large glass doors, and a wooden archway.

A kitchen with a brick wall, wooden cabinets, a coffee machine, a waffle maker, and a large window with a view of trees.

A modern living room with a stone fireplace, a flat-screen TV mounted on the wall, and a sectional sofa.

A spacious indoor area with a large gray sofa, multiple tables, chairs, and a television mounted on the wall.

Staybridge Suites Columbia by IHG

Downtown Columbia

10/10 Exceptional

We have a child at the university and stayed here for a weekend visit. I had never been, but my husband had stayed years ago for a swim meet. He insisted I book here, though I wanted to stay at the Hilton. I was so pleasantly surprised when I arrived at the Staybridge! The staff was super friendly, and exceptionally efficient. The room was very spacious, and the little kitchen was perfect! The included breakfast was also excellent. I will stay here every visit to Columbia!

Karen

A hotel room with a bed, a desk with a computer, a nightstand, a lamp, and a window with curtains.

A modern kitchen with stainless steel appliances, a dining table with red chairs, and wooden cabinets.

A conference room with long tables and chairs, a projector screen, a storage area, and a carpeted floor.

A modern hotel room with a sofa, a small table, a desk with a lamp, and a chair.

Residence Inn Columbia West/Lexington

West Columbia

10/10 Exceptional

Anthony

A modern dining area with wooden tables and chairs, a central bar, and colorful wall art.

A hotel room with two beds, a wooden headboard, a desk with a lamp, a window with curtains, and a painting on the wall.

A modern kitchen with a built-in refrigerator, a coffee machine, and a painting on the wall.

A modern hotel with a sign reading "Best Western PLUS". It features a multi-story structure with large windows and a well-maintained lawn in front.

Best Western Plus Lexington Inn

Downtown Lexington

10/10 Exceptional

Amy

Frequently Asked Questions

What accommodations do travelers like in Cayce?

Guests like Country Inn & Suites by Radisson, Columbia Airport, SC, Econo Lodge Inn & Suites Cayce I-26 Airport and Masters Inn Columbia I-26.

Can I book refundable accommodations in Cayce?

If you want the flexibility to change your plans to Cayce, most properties offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where should I consider staying in Cayce if I want an affordable accommodation?

Country Inn & Suites by Radisson, Columbia Airport, SC is an accommodation you might want to consider that'll save you money.

Where can I stay in Cayce if I want a vacation home instead of a traditional hotel?

If you're looking for a good alternative to a hotel, review our selection of 19 vacation homes. In addition, you can choose from 5 apartments.

What will the weather in Cayce be like during my vacation?

July and August are typically the warmest months in Cayce when the average temp is 79°F. January and February are the coldest months when the average temperature is 50°F. August and July are the months with the most rain.

Why should I book my Cayce accommodation with Hotels.com?

There are lots of reasons to book your Cayce trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Hotels in Cayce

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Cayce?

1. Courtyard by Marriott Columbia Cayce

2. Country Inn & Suites by Radisson, Columbia Airport, SC

3. Econo Lodge Inn & Suites Cayce I-26 Airport

4. Masters Inn Columbia I-26

5. Sleep Inn Columbia Airport

6. Quality Inn West Columbia - Cayce

7. Motel 6 West Columbia, SC - Airport

8. Tru By Hilton Columbia Downtown

9. Gallus Stadium Park Inn, an Ascend Collection Hotel

10. Hampton Inn Columbia-I-26 Airport

11. Fairfield Inn & Suites by Marriott Columbia Downtown

12. Homewood Suites By Hilton Columbia Downtown

13. SpringHill Suites by Marriott Columbia Downtown/The Vista

14. Cambria Hotel Columbia Downtown The Vista

15. Tru By Hilton Columbia Greystone

16. Hyatt Place Columbia/Downtown/The Vista

17. Quality Inn Columbia Airport

18. Sheraton Columbia Downtown Hotel

19. Courtyard by Marriott Columbia Downtown at USC

20. Hampton Inn Columbia-Downtown Historic District

Go beyond your typical stay in Cayce

Price trends for hotels in Cayce

October

Top landmarks in Cayce

Congaree Creek Heritage Preserve

Cayce Historical Museum

Learn more about Cayce

Check out reviews of Cayce hotels guests love

Courtyard by Marriott Columbia Cayce

10/10 Exceptional

The Lantern Hotel Columbia

10/10 Exceptional

Hotel Trundle

10/10 Exceptional

Homewood Suites By Hilton Columbia Downtown

10/10 Exceptional

The 1425 Inn

10/10 Exceptional

Hampton Inn & Suites Lexington Columbia

10/10 Exceptional

Tru By Hilton Columbia Downtown

10/10 Exceptional

Cambria Hotel Columbia Downtown The Vista

10/10 Exceptional

Graduate by Hilton Columbia SC

10/10 Exceptional

Springhill Suites by Marriott Columbia near Fort Jackson

10/10 Exceptional

Home2 Suites by Hilton Columbia Southeast Fort Jackson

10/10 Exceptional

Holiday Inn Express & Suites Lexington by IHG

10/10 Exceptional

Tru By Hilton Columbia Greystone

10/10 Exceptional

Staybridge Suites Columbia by IHG

10/10 Exceptional

Residence Inn Columbia West/Lexington

10/10 Exceptional

Best Western Plus Lexington Inn

10/10 Exceptional

Frequently Asked Questions

What accommodations do travelers like in Cayce?

Can I book refundable accommodations in Cayce?

Where should I consider staying in Cayce if I want an affordable accommodation?

Where can I stay in Cayce if I want a vacation home instead of a traditional hotel?

What will the weather in Cayce be like during my vacation?

Why should I book my Cayce accommodation with Hotels.com?