Hotels in La Mesa

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Check prices for these dates

Tonight
Oct 8 - Oct 9
Tomorrow
Oct 9 - Oct 10
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Where to stay in La Mesa?

A multi-story hotel with a brick facade, multiple windows, and a fire escape.
A lobby with a seating area featuring two armchairs and a table, a decorative wall, and a chandelier.
A hotel room with a large walk-in closet, a bed with white bedding, a bedside table with a lamp, and a wall-mounted mirror.
A person holding a bottle and glasses, wearing a dark shirt with a logo and an apron.

1. The Sofia Hotel

The Sofia Hotel
Downtown San Diego
$147
$199 total
includes taxes & fees
Oct 26 - Oct 27
The Sofia Hotel
Poolside bar
A Hard Rock Hotel with a prominent Hard Rock Cafe sign, a large marquee, and a modern building facade.
A modern bar area with a circular bar, multiple stools, and a large screen.
A modern lobby with a digital display wall, reception desks, and a spacious, well-lit area.

2. Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
Downtown San Diego
$195
$274 total
includes taxes & fees
Oct 25 - Oct 26
Hard Rock Hotel San Diego
A hotel courtyard with outdoor seating, palm trees, and a view of the ocean at dusk.
A high-rise urban area with modern buildings, palm trees, and a clear sky.
A marina with multiple boats docked and tall buildings in the background.
A modern living room with a green sofa, a round glass table, and a flat-screen TV mounted on the wall.

3. Wyndham San Diego Bayside

Wyndham San Diego Bayside
Downtown San Diego
$152
$211 total
includes taxes & fees
Oct 25 - Oct 26
Wyndham San Diego Bayside
A resort with a large swimming pool surrounded by lounge chairs and palm trees.
A hotel with a curved entrance, palm trees, and a parking lot.
A bar area with wooden chairs and tables, a bar counter with various bottles, and a sign reading "BEACH BUMS CATER HERE".
A lobby with seating areas, a piano, and a reception desk.

4. Handlery Hotel

Handlery Hotel
Mission Valley
$103
$119 total
includes taxes & fees
Oct 15 - Oct 16
Handlery Hotel
A hotel room with a large window offering a city view, a bed, a chair, and a small table.
A modern reception area with a wooden reception desk, a large flat-screen TV displaying a scenic ocean view, and a seating area with pink chairs.
A tall, modern hotel with a curved facade, multiple balconies, and an American flag.
A room with a view of a cityscape, a chair with a patterned cushion, and a floor lamp.

5. The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
Downtown San Diego
$143
$166 total
includes taxes & fees
Nov 8 - Nov 9
The DEXTRO Little Italy, BW Premier Collection
A pathway flanked by neatly trimmed hedges and a building with a balcony.
A lobby with a mosaic fountain, seating area, and a book display.
A courtyard with a small pond, trees, and a fountain.
A courtyard with a small water feature surrounded by rocks and greenery.

6. California Suites Hotel

California Suites Hotel
Clairemont
$76
$87 total
includes taxes & fees
Oct 12 - Oct 13
California Suites Hotel
A modern bar area with a curved counter, multiple bar stools, and a large window offering a view of the cityscape.
A rooftop lounge area with outdoor seating, a pool, and umbrellas.
An outdoor patio area with seating arrangements, including sofas, chairs, and round tables.
A spacious lobby with a high ceiling, a large sectional sofa, multiple seating areas, and a modern chandelier.

7. Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
Downtown San Diego
$285
$376 total
includes taxes & fees
Oct 28 - Oct 29
Omni San Diego Hotel at the Ballpark
A rectangular swimming pool with lounge chairs and umbrellas, surrounded by tall trees and greenery.
A hotel room with a large window with blinds, a round mirror, two teal chairs, a small round table, and a television on a wooden cabinet.
A compact kitchen with a microwave, coffee maker, and sink.
A hotel room with a large bed, a TV, a desk, and a painting on the wall.

8. Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle
Mission Valley
$88
$102 total
includes taxes & fees
Oct 25 - Oct 26
Days Inn by Wyndham San Diego Hotel Circle
An aerial view of a resort with a central swimming pool, palm trees, and a view of the ocean and beach.
A modern building with a curved roof, surrounded by lush tropical vegetation.
An outdoor dining area with tables and chairs, umbrellas, and string lights against a sunset backdrop.
A living room with a fireplace, a television, a sofa, a chair, a round coffee table, and a view of the ocean through glass doors.

9. Paradise Point Resort & Spa

Paradise Point Resort & Spa
Mission Bay
$208
$292 total
includes taxes & fees
Nov 1 - Nov 2
Paradise Point Resort & Spa
A pool area with a hot tub, lounge chairs, and umbrellas.
A marina with boats, a bridge, and a building with a pool and palm trees.
A dining table set for a wedding with floral centerpieces and candles, overlooking a marina with boats.
An outdoor seating area with a fire pit table, surrounded by chairs and umbrellas, in a courtyard with palm trees and a building in the background.

10. The Dana on Mission Bay

The Dana on Mission Bay
Mission Bay
$169
$223 total
includes taxes & fees
Nov 1 - Nov 2
The Dana on Mission Bay
A bar area with a glass ceiling, a central bar counter, and multiple stools.
A large swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a striped facade.
A luxurious interior with a large chandelier, patterned sofas, and a view of a cityscape through a large window.
A checkered floor with round tables and chairs, a patterned ceiling, and large windows.

11. Lafayette Hotel & Club

Lafayette Hotel & Club
University Heights
$273
$314 total
includes taxes & fees
Oct 19 - Oct 20
Lafayette Hotel & Club
A modern hotel room with a large bed, a sofa, a TV, and a city view.
A rooftop pool with lounge chairs and umbrellas, a clear sky, and a high-rise building in the background.
A high-rise hotel with multiple floors, a prominent curved glass facade, and a view of a bridge and water body in the background.
A spacious hotel dining area with multiple tables and chairs, large windows, and a view of the outdoors.

12. Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
Downtown San Diego
$229
$320 total
includes taxes & fees
Oct 9 - Oct 10
Manchester Grand Hyatt San Diego
A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
A modern interior with wooden panel ceilings, patterned seating, and a central bar area.
A swimming pool with blue lounge chairs and umbrellas, surrounded by a building with balconies.
A hotel room with a large bed, a wooden nightstand, a bench, a desk with a TV, and a chair.

13. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
$172
$198 total
includes taxes & fees
Oct 25 - Oct 26
Legacy Resort Hotel & Spa
An aerial view of a resort with multiple swimming pools, lounge areas, and palm trees.
A modern hotel with a prominent circular tower and a glass facade.
An outdoor patio area with tables and chairs, a fire pit, and string lights.
A bar area with a long counter, multiple stools, and hanging wicker lamps.

14. Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
Downtown San Diego
$285
$378 total
includes taxes & fees
Oct 29 - Oct 30
Marriott Marquis San Diego Marina
A hotel lobby with a waterfall feature, outdoor seating area, and multiple floors with balconies.
A spacious lobby with two sofas, a reception desk, and a large chandelier.
A bar area with a long counter, multiple stools, and a television screen.
A hotel with a large pool area, outdoor seating, and a well-maintained garden.

15. Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
Mission Valley
$118
$136 total
includes taxes & fees
Oct 26 - Oct 27
Crowne Plaza San Diego - Mission Valley by IHG
A modern indoor swimming pool with lounge chairs and palm trees.
A marina with boats, a modern building, and a sunset.
An outdoor dining area with multiple round tables and chairs, surrounded by palm trees and a view of the sea.
A modern bar area with a curved counter, bar stools, and a large chandelier.

16. Hilton San Diego Bayfront

Hilton San Diego Bayfront
Downtown San Diego
$188
$267 total
includes taxes & fees
Oct 25 - Oct 26
Hilton San Diego Bayfront
A hotel lobby with a 'Lobby' sign, palm trees, and a sunset sky.
A gym with treadmills, elliptical machines, and a stationary bike.
A modern hotel lobby with a reception desk, seating area with chairs and a sofa, a ceiling fan, and a large window with curtains.
An outdoor patio area with tables and chairs, red umbrellas, and a view of palm trees and a building with a 'BLW' sign.

17. Best Western Seven Seas

Best Western Seven Seas
Mission Valley
$85
$97 total
includes taxes & fees
Oct 12 - Oct 13
Best Western Seven Seas
A restaurant with outdoor seating, brick walls, and decorative lighting.
A vintage car parked in front of a building with a sign that reads "Horton Grand Hotel."
A spacious lobby with high ceilings, large windows, and elegant furniture.
A spacious lobby with a bar area, seating arrangements, and a large chandelier.

18. The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter
Downtown San Diego
$164
$218 total
includes taxes & fees
Nov 8 - Nov 9
The Horton Grand, Downtown/Gaslamp Quarter
A cityscape at dusk with high-rise buildings and a bridge in the distance.
A modern bar area with a curved counter, bar stools, and a seating area with tables and chairs.
A modern hotel lobby with a wooden reception desk, a patterned wall, and a long corridor leading to a bright area with a view.
A rooftop pool area with lounge chairs and umbrellas, surrounded by modern buildings and a cityscape at sunset.

19. Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
Downtown San Diego
$161
$187 total
includes taxes & fees
Oct 25 - Oct 26
Courtyard by Marriott San Diego Downtown Little Italy
A high-rise hotel with multiple floors, a prominent sign at the top, and a well-lit facade.
A modern lobby with seating areas, a reception desk, and a sign indicating elevators to parking and a street.
A lobby with a purple-lit ceiling, a large wall mural, and seating areas.
A spacious lobby with a high ceiling, leather seating, multiple tables, and a large flat-screen TV mounted on the wall.

20. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
Downtown San Diego
$186
$216 total
includes taxes & fees
Oct 25 - Oct 26
Marriott Vacation Club®, San Diego
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A hotel room with a bed, a bedside table with a phone, and a nightstand.
A reception desk with a sign promoting the My6 app, a clock, and framed pictures on the wall.
A building with a '6' sign, surrounded by lush greenery and palm trees.
A hotel room with a large window, a poster on the wall, and a tiled floor.

Motel 6 La Mesa, CA - San Diego

Motel 6 La Mesa, CA - San Diego
La Mesa
$42 off
$114
per night
$251 total
includes taxes & fees
Motel 6 La Mesa, CA - San Diego
A building with a 'Lobby' and 'Vacancy' sign, surrounded by a variety of flowering plants.
A laundry room with four front-loading washing machines, a dryer, and a vending machine.
A swimming pool with a metal ladder, a blue chair, and a white chair.
A hotel room with two beds, a chair, a desk, and a lamp.

Heritage Inn La Mesa

Heritage Inn La Mesa
La Mesa
$108
per night
$237 total
includes taxes & fees
Heritage Inn La Mesa
A spacious lobby with leather sofas, a round coffee table with fruit, and a ceiling adorned with colorful hanging ornaments.
A gym with treadmills, ellipticals, and weight machines.
A hotel room with a large bed, a sofa, a nightstand with a lamp, and a vase of flowers.
A swimming pool with a wooden deck, lounge chairs, and a gated entrance.

Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego
La Mesa
$278
per night
$612 total
includes taxes & fees
Best Western Plus La Mesa San Diego
A spacious living room with two sofas, a coffee table, and a staircase leading to an upper level.
A living room with leather sofas, a flat-screen TV, a fireplace, and a dining table.
A swimming pool with a tiled edge, a patio area with chairs, and a house in the background.
A dining area with a glass table, wooden chairs, and a chandelier.

Spacious Getaway w/ Pool in La Mesa!

Spacious Getaway w/ Pool in La Mesa!
Casa de Oro-Mount Helix
$289
per night
$1,021 total
includes taxes & fees
Spacious Getaway w/ Pool in La Mesa!
A modern hotel room with two beds, a balcony, and a desk.
A motel with a prominent '6' sign, a parking lot with several cars, and a well-lit entrance.
A motel with a red-tiled roof, multiple balconies, and a parking area with several vehicles.
A motel with a covered parking area, a 'No Parking' sign, and a 'Fire Lane' sign.

Motel 6 La Mesa, CA

Motel 6 La Mesa, CA
La Mesa
$130
per night
$286 total
includes taxes & fees
Sign in for extra savings
Motel 6 La Mesa, CA
Our prices for hotels in La Mesa are cheapest in January
Price trends for hotels in La Mesa
Pricing is based on two traveler single night rates
View properties in October
Typical weather for La Mesa
October
High 26°C / low 16°C. Sunny most days.
View properties in October
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Monthly weather averages (˚C)

Top neighborhoods in La Mesa

A town with a mountain in the background, a clear sky, and scattered clouds.
A town with a mountain in the background.

Casa de Oro-Mount Helix

La Mesa's Casa de Oro-Mount Helix neighborhood offers attractions including Mount Helix Park.

A large white cross against a cloudy sky.

Mount Helix

The Mount Helix neighborhood offers attractions such as Mount Helix Park and FAITH CHAPEL.

Top landmarks in La Mesa

Mount Helix Park

7.4/10 (59 reviews)
If you're planning a bit of sightseeing head to Mount Helix Park— just one of the monuments in Casa de Oro-Mount Helix. Why not take a stroll along the port and watch the sunset while you're here?
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La Mesa Memorial Fine Arts Center

La Mesa Memorial Fine Arts Center is in the heart of La Mesa, so why not stop by during your stay. If you have fun at La Mesa Memorial Fine Arts Center, you'll love San Diego Zoo, which isn't far.
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The Bancroft

If you find yourself in Mount Helix, you can stop off for a few drinks or snacks at The Bancroft.
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FAITH CHAPEL

FAITH CHAPEL is a venue in Mount Helix.
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Learn more about La Mesa

Between the bustle of San Diego and the quiet of the hills, La Mesa lives up to its 'Jewel of the Hills' nickname without trying too hard. The historic Village area offers boutiques and cafés where locals actually eat, not just places that survive on tourist traffic. Mount Helix rewards a short climb with panoramic views that explain why everyone in California seems suspiciously content. Lake Murray Park provides a refreshing escape where fishing lines dangle alongside kayakers who've discovered this urban oasis. Train enthusiasts find unexpected delight at the Pacific Southwest Railway Museum, where vintage locomotives sit frozen in time.

See all hotels in La Mesa
A sunset over a mountainous landscape with scattered clouds.

Check out reviews of La Mesa hotels guests love

Kings Inn San Diego

Kings Inn San Diego

10/10 Excellent
"."
Deepa 2-night trip
Posted 2 hours ago
Kings Inn San Diego
The Sofia Hotel

The Sofia Hotel

8/10 Good
"Really loved the staff and how historic the Sofia Hotel is. However, it could use an update (while still maintaining its integrity)."
John 2-night trip
Posted 4 hours ago
The Sofia Hotel
California Suites Hotel

California Suites Hotel

8/10 Good
"Hotel is nice but dont expect top notch amenities. The price is cheap, the area is decent, and the hotel is dated but our room was quiet. It is a big sized room for the price."
Robert 1-night trip
Posted 6 hours ago
California Suites Hotel
Sheraton San Diego Resort

Sheraton San Diego Resort

8/10 Good
"Great location overall I’ll recommended to everybody with the families"
Stepan 2-night trip
Posted 6 hours ago
Sheraton San Diego Resort
Ocean Beach Hotel

Ocean Beach Hotel

10/10 Excellent
":)"
Josh 1-night trip
Posted 6 hours ago
Ocean Beach Hotel
Best Western Seven Seas

Best Western Seven Seas

10/10 Excellent
"It was good"
Mike 3-night trip
Posted 14 hours ago
Best Western Seven Seas
Paradise Point Resort & Spa

Paradise Point Resort & Spa

10/10 Excellent
"Lovely place!!"
Pascale Adel 3-night trip
Posted 18 hours ago
Paradise Point Resort & Spa

Frequently asked questions

What accommodations do travelers like in La Mesa?
Guests like Best Western Seven Seas, Wyndham San Diego Bayside and Handlery Hotel.
Can I book a refundable accommodation in La Mesa?
If you need the flexibility to change your travel plans to La Mesa, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in La Mesa if I want a vacation home instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 65 vacation homes. In addition, you can choose from 10 apartments.
What will the weather in La Mesa be like during my trip?
August and September are typically the warmest months in La Mesa when the average temp is 72°F. February and January are the coldest months when the average temperature is 56°F. December and February are the months with the most rain.
Why should I book my La Mesa hotel through Hotels.com?
There are lots of reasons to book your La Mesa trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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