Business Hotels in Key Largo

October 2026
November 2026

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Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Business Hotels in Key Largo

1. Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay
Key Largo
$130
$147 total
includes taxes & fees
Sep 28 - Sep 29
Hampton Inn Key Largo Manatee Bay

2. Bayside Inn Key Largo

Bayside Inn Key Largo
Key Largo
$122
$163 total
includes taxes & fees
Oct 7 - Oct 8
Bayside Inn Key Largo

3. Courtyard by Marriott Key Largo

Courtyard by Marriott Key Largo
Key Largo
$143
$161 total
includes taxes & fees
Sep 27 - Sep 28
Courtyard by Marriott Key Largo

4. Dove Creek Resort & Marina, Trademark Collection by Wyndham

Dove Creek Resort & Marina, Trademark Collection by Wyndham
Key Largo
$94
$137 total
includes taxes & fees
Sep 27 - Sep 28
Dove Creek Resort & Marina, Trademark Collection by Wyndham

5. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
$263
$351 total
includes taxes & fees
Oct 4 - Oct 5
Playa Largo Resort & Spa, Autograph Collection

6. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
$237
$322 total
includes taxes & fees
Sep 30 - Oct 1
Baker's Cay Resort Key Largo, Curio Collection by Hilton

7. Gilbert's Resort

Gilbert's Resort
Key Largo
$237
$267 total
includes taxes & fees
Sep 22 - Sep 23
Gilbert's Resort

8. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
$149
$241 total
includes taxes & fees
Sep 23 - Sep 24
Cheeca Lodge & Spa

9. Islander Resort

Islander Resort
Matecumbe
$196
$288 total
includes taxes & fees
Sep 27 - Sep 28
Islander Resort

10. Hampton Inn & Suites Homestead Miami South

Hampton Inn & Suites Homestead Miami South
Homestead
$85
$97 total
includes taxes & fees
Sep 29 - Sep 30
Hampton Inn & Suites Homestead Miami South

11. Hilton Garden Inn Homestead

Hilton Garden Inn Homestead
Homestead
$81
$92 total
includes taxes & fees
Sep 27 - Sep 28
Hilton Garden Inn Homestead

12. Travelodge by Wyndham Florida City/Homestead/Everglades

Travelodge by Wyndham Florida City/Homestead/Everglades
Florida City
$65
$74 total
includes taxes & fees
Sep 27 - Sep 28
Travelodge by Wyndham Florida City/Homestead/Everglades

13. Fairway Inn Florida City Homestead Everglades

Fairway Inn Florida City Homestead Everglades
Florida City
$53
$60 total
includes taxes & fees
Oct 13 - Oct 14
Fairway Inn Florida City Homestead Everglades

14. Quality Inn Florida City - Gateway to the Keys

Quality Inn Florida City - Gateway to the Keys
Florida City
$63
$71 total
includes taxes & fees
Sep 29 - Sep 30
Quality Inn Florida City - Gateway to the Keys

15. Fairfield by Marriott Inn & Suites Homestead Florida City

Fairfield by Marriott Inn & Suites Homestead Florida City
Florida City
$80
$91 total
includes taxes & fees
Sep 28 - Sep 29
Fairfield by Marriott Inn & Suites Homestead Florida City

16. Super 8 by Wyndham Homestead/Florida City/Gateway to Keys

Super 8 by Wyndham Homestead/Florida City/Gateway to Keys
Florida City
$55
$62 total
includes taxes & fees
Sep 22 - Sep 23
Super 8 by Wyndham Homestead/Florida City/Gateway to Keys

17. TownePlace Suites by Marriott Miami Homestead

TownePlace Suites by Marriott Miami Homestead
Homestead
$116
$132 total
includes taxes & fees
Sep 29 - Sep 30
TownePlace Suites by Marriott Miami Homestead

18. Home2 Suites by Hilton Florida City, FL

Home2 Suites by Hilton Florida City, FL
Florida City
$110
$124 total
includes taxes & fees
Sep 27 - Sep 28
Home2 Suites by Hilton Florida City, FL

19. Courtyard by Marriott Miami Homestead

Courtyard by Marriott Miami Homestead
Homestead
$116
$131 total
includes taxes & fees
Oct 12 - Oct 13
Courtyard by Marriott Miami Homestead

20. Garden Inn Homestead/Everglades/Gateway to Keys

Garden Inn Homestead/Everglades/Gateway to Keys
Homestead
$50
$56 total
includes taxes & fees
Oct 4 - Oct 5
Garden Inn Homestead/Everglades/Gateway to Keys
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Top neighborhoods in Key Largo

Rock Harbor

Key Largo's Rock Harbor neighborhood offers attractions including Bluefin Rock Harbor Marina.

Key Largo Village

Key Largo Village wraps you in a tropical paradise where dive shops, seafood joints, and tiki bars create a lively waterfront scene. The neighborhood buzzes with charter boats and sun-soaked docks while providing easy access to underwater adventures at John Pennekamp Coral Reef State Park. Everglades National Park sits nearby, offering a perfect day trip for nature lovers between snorkeling sessions. Fresh-caught seafood dominates local menus, with restaurants offering deck seating and stunning water views. Most visitors stay in waterfront resorts or boutique inns, many featuring private boat slips. Getting around requires a car, though the village core is walkable with plenty of free parking throughout.

Key Largo Park

Key Largo Park gives you that perfect Florida Keys vibe without the highway hustle. Canal-front homes and private docks create a waterfront wonderland where you can fish, swim, or just watch the boats drift by. Mornings bring bird calls and gentle waves, while evenings deliver spectacular sunsets over Florida Bay. The neighborhood sits just minutes from underwater adventures at John Pennekamp Coral Reef State Park. You won't find restaurants or shops within the neighborhood itself, but that's part of the charm. Most vacation rentals come with fully equipped kitchens and tropical backyards perfect for grilling your fresh catch. A quick drive takes you to Key Largo's dining spots when you're ready to venture out.

Cross Key Waterways

Cross Key Waterways puts you right where the action happens in Key Largo—on the water. Canal-front homes with private docks mean you can boat straight from your backyard to the Atlantic Ocean or Florida Bay. The neighborhood sits close to must-see spots like John Pennekamp Coral Reef State Park and the MarineLab Undersea Laboratory. This peaceful residential area offers vacation rentals with tropical vibes and plenty of privacy. You'll need to drive about 5-10 minutes to find restaurants and shops along the main highway. Most properties come with pools, boat access, and those gorgeous Florida Keys water views.

Top landmarks in Key Largo

A beach with palm trees, a 'DO NOT PASS' sign, a 'SEVEN MILE BRIDGE' sign, and a bench.

Florida Keys Visitor Center - Key Largo

8.8/10 (549 reviews)
Florida Keys Visitor Center - Key Largo is worth a visit, located 6.4 mi (10.3 km) from central Key Largo. Why not take a stroll along the beaches and watch the sunset while you're here?
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A wooden pavilion with picnic tables in a forested area.

Dagny Johnson Key Largo Hammock Botanical State Park

8.2/10 (113 reviews)
Dagny Johnson Key Largo Hammock Botanical State Park is 16.3 mi (26.2 km) from central Key Largo, why not stop by during your stay. Why not take a stroll along the beaches and watch the sunset while you're here?
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Jimmy Johnson's Big Chill

8.4/10 (687 reviews)
Imagine strolling along Jimmy Johnson's Big Chill for some great waterfront pics when in the heart of Key Largo.
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Caribbean Club Bar

8.6/10 (312 reviews)
If seeing the sights is on your list of things to do, head to Caribbean Club Bar— just one of the landmarks located 4.5 mi (7.3 km) from central Key Largo. Why not take a stroll along the beaches and watch the sunset while you're here?
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MarineLab Undersea Laboratory

9.2/10 (35 reviews)
MarineLab Undersea Laboratory is 3.8 mi (6.1 km) from central Key Largo, why not stop by during your stay. Why not take a stroll along the beaches and watch the sunset while you're here? If you have fun at MarineLab Undersea Laboratory, you'll love John Pennekamp Coral Reef State Park and Jacob's Aquatic Center, both located nearby.
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Jacob's Aquatic Center

8.8/10 (27 reviews)
Jacob's Aquatic Center is in the heart of Key Largo, so why not stop by during your stay. Why not take a stroll along the beaches and watch the sunset while you're here? If you have fun at Jacob's Aquatic Center, you'll love John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory, both located nearby.
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Bluefin Rock Harbor Marina

8.6/10 (123 reviews)
You can stroll along Bluefin Rock Harbor Marina for relaxing water views when you're in Rock Harbor.
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Key Largo Hammocks State Botanical Site

8.4/10 (256 reviews)
Ready for an education in local botany? Key Largo Hammocks State Botanical Site should make your list of places to visit, located 8.4 mi (13.5 km) from central Key Largo. Why not take a stroll along the beaches and watch the sunset while you're here? If you like Key Largo Hammocks State Botanical Site, you'll love New Mahogany Hammock State Botanical Site, just a short drive away.
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About the destination

Key Largo is a relaxing place known for its marina. Enjoy fun activities like dolphin viewing and boating. Why not spend time at Jacob's Aquatic Center and John Pennekamp Coral Reef State Park?While you're in town, don't miss a chance to see sights like Jimmy Johnson's Big Chill and Bluefin Rock Harbor Marina.