Hotels in Santa Cruz

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Where to stay in Santa Cruz?

A building with a pool, outdoor seating, and a hot tub.

An outdoor dining area with tables and chairs, string lights, and a covered section.

A multi-story building with multiple windows, a staircase, and a paved entrance area.

A well-maintained grassy lawn with a few trees and a building in the background.

Hotel Finca Las Hortensias

Tepotzotlán

$64

$76 total

includes taxes & fees

Sep 3 - Sep 4

A rooftop spa with two massage tables, a hot tub, and a seating area.

A bar area with a stone counter, metal chairs, and a variety of bottles and glasses.

A dining table with plates of food, wine glasses, and cutlery.

A stone entrance with a lit frame, a sign reading "La Morada Boutique Hotel & Spa", and a palm tree in the background.

La Morada Tepotzotlan Boutique & Spa

Tepotzotlán

$231

$278 total

includes taxes & fees

Aug 28 - Aug 29

A spacious lobby with a reception desk, seating area, and large windows.

An outdoor patio with tables and chairs, a large umbrella, and a potted plant.

A dining area with a table, chairs, a meal, a drink, and a counter with a TV in the background.

A hotel room with two beds, a desk, a chair, a wardrobe, and a window with a view.

City Express by Marriott Tepotzotlan

Tepotzotlán

$72

$86 total

includes taxes & fees

Sep 19 - Sep 20

A modern lobby with large windows, a sofa, ottomans, and a coffee table.

A modern dining area with a long table and chairs, large windows with a view of a cityscape and mountains, and hanging pendant lights.

A gym with treadmills, elliptical machines, and a mirror wall.

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham

Cuautitlan Izcalli

$70

$84 total

includes taxes & fees

Sep 4 - Sep 5

A modern reception area with a blue wall, a reception desk, and a large window offering a view of the outside. There are two sofas and a coffee table in the seating area.

A modern living room with a long white bookshelf, a blue wall, and a dining area in the background.

A modern living room with a large flat-screen TV, wooden shelving, a beige sofa, and a glass partition wall.

A modern dining area with white tables and blue chairs, a large black pillar, and a wall-mounted TV.

One Cuautitlan

Cuautitlan Izcalli

$87

$104 total

includes taxes & fees

Aug 29 - Aug 30

A pool area with lounge chairs and umbrellas, a tiled pool, and a modern building in the background.

A hotel room with two beds, a desk with a computer, and a TV.

A modern bar area with a red and white color scheme, featuring a menu board, multiple shelves with bottles, and bar stools.

A modern hotel building with a prominent entrance and a clear sky.

Fiesta Inn Cuautitlan

Cuautitlan Izcalli

$90

$108 total

includes taxes & fees

Sep 4 - Sep 5

A modern hotel reception area with a white reception desk, a digital screen displaying the weather, and a green sofa.

A hotel room with two beds, a headboard, and a curtain.

Fiesta Inn Express Perinorte

Tultitlan

$84

$101 total

includes taxes & fees

Sep 4 - Sep 5

An outdoor patio with string lights, wooden tables, and chairs.

A buffet setup with multiple food stations, overhead lighting, and a red counter.

ibis Mexico Perinorte

Cuautitlan Izcalli

$48

$57 total

includes taxes & fees

Sep 11 - Sep 12

A hotel entrance with a modern design, featuring a glass facade, a central staircase, and a Christmas tree.

A hotel room with a bed, a chair, and a standing lamp.

A modern hotel lobby with a wooden floor, a white sofa, a coffee table with decorative plants, and a large abstract painting on the wall.

A hotel room with a wooden door, a bed with a headboard, and a small potted plant in the background.

Antigua Hotel Boutique

Ciudad López Mateos

$73

$88 total

includes taxes & fees

Aug 30 - Aug 31

A spacious lobby with a modern design, featuring a large seating area, a reception desk, and a chandelier.

A modern kitchen with a large island, bar stools, and a view of a bridge.

A rooftop bar with a long counter, multiple bar stools, and outdoor seating.

An outdoor patio with a wooden ceiling, seating arrangements, and a view of the airport in the background.

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Zumpango

$112

$135 total

includes taxes & fees

Sep 3 - Sep 4

An indoor swimming pool with lounge chairs and a table, surrounded by white walls and blue ceiling accents.

A bar area with a large jar of iced tea, glasses on a tray, and a sign with 'There is Beauty Everywhere'.

A hotel room with two beds, a window, a bedside table, and a wall-mounted lamp.

An ornate wooden door, a stained glass window, and a painting on the wall.

Ramada by Wyndham CDMX Perinorte

Tlalnepantla de Baz

$54

$65 total

includes taxes & fees

Sep 8 - Sep 9

A modern building with a cylindrical structure to the left and a glass facade to the right.

A restaurant with wooden walls and tables set with white tablecloths and orange chairs.

A gym with a treadmill, elliptical, and stationary bike.

A hotel room with two beds, a large mirror, a sink, and a television.

Hotel Madeira

Ciudad López Mateos

$47

$56 total

includes taxes & fees

Aug 28 - Aug 29

A buffet with various food items and a sign indicating a vanilla dessert.

A modern living room with two leather armchairs, a round table, and a dark accent wall.

A hotel room with two beds, a wardrobe, a walk-in closet, and a wooden accent wall.

Verticca Hotel

Ojo de Agua

$97

$117 total

includes taxes & fees

Sep 7 - Sep 8

A courtyard with white outdoor furniture, large umbrellas, and a building in the background.

A buffet with various desserts and beverages.

A spacious lobby with a reception desk, modern seating, large windows, and a high ceiling.

A modern hotel with a swimming pool, outdoor seating, and a covered patio area.

Krystal Satélite María Bárbara

San Lucas Tepetlacalco

$77

$92 total

includes taxes & fees

Aug 28 - Aug 29

A modern lobby with a red sofa, colorful chairs, a round table, and a ceiling with various words and phrases.

A hotel room with two beds, a desk, a laptop, and a large window with curtains.

ibis Mexico Tlalnepantla

Tlalnepantla Centro

$55

$66 total

includes taxes & fees

Sep 8 - Sep 9

A rooftop swimming pool with lounge chairs and a view of the city.

A restaurant with a long counter, multiple tables, and hanging pendant lights.

A person sitting on a bed with a glass of orange juice, a plate of fruit, and a magazine.

A laptop on a desk with a cup, a lamp, and a chair, overlooking a hilly landscape.

Fiesta Inn Ecatepec

Ecatepec de Morelos

$88

$106 total

includes taxes & fees

Sep 4 - Sep 5

A hotel entrance with a curved awning, a fountain, and a well-lit building facade.

A buffet with various food items and beverages, set against a brick wall.

A Starbucks coffee shop with a menu board, a beverage display, and a refrigerated section.

A spacious lobby with a grand piano, a reception desk, and wooden doors.

Real Inn Perinorte

Tlalnepantla de Baz

$65

$78 total

includes taxes & fees

Sep 12 - Sep 13

A modern dining area with a high ceiling, large windows, and a view of the city.

A modern office space with a round table, chairs, a sofa, and a view of the city through large windows.

A modern reception area with a reception desk, seating arrangements, and a large window providing a view of the outside.

A modern dining area with a high ceiling, large windows, and a view of a cityscape.

City Express Plus by Marriott Ciudad de México Mundo E

Jardines de Santa Monica

$77

$92 total

includes taxes & fees

Sep 4 - Sep 5

An outdoor dining area with tables and chairs, a glass wall, and a metal structure overhead.

A spacious lobby with a large sofa, two armchairs, and a matching ottoman.

A bar area with a central bar counter, multiple stools, and a unique liquor display.

A modern restaurant interior with high ceilings, geometric wall panels, and a mix of seating arrangements including tables and booths.

Fiesta Americana México Satélite

Tlalnepantla de Baz

$111

$133 total

includes taxes & fees

Sep 12 - Sep 13

A spacious lobby with modern lighting, a reception desk, seating area, and large windows.

A modern living room with a sofa, ottomans, a coffee table, and a TV.

A hotel building with a sign reading "cityexpress hotels" and multiple illuminated windows.

A buffet counter with various food items, a coffee machine, and a microwave.

City Express by Marriott Ciudad de México Tlalnepantla

Ciudad Satélite

$63

$76 total

includes taxes & fees

Sep 4 - Sep 5

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Go beyond your typical stay in Santa Cruz

Pet friendly

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Spa

Pool

Hot tub

Family friendly

Check out reviews of Santa Cruz hotels guests love

Casa Olea

10/10 Excellent

"Property was clean and well maintained. Staff was nice and helpful. Room was spacious and great shower pressure!"

InterContinental Presidente Mexico City by IHG

10/10 Excellent

"I have been staying at this hotel since forever and love it! Prime location, very clean, and efficient."

Capitalia Antara Polanco

8/10 Good

"Very nice and spacious apartment in a great location. The staff was friendly, and the breakfast was good. It feels more like an Airbnb, so daily room cleaning is not provided."

Kukun Homero Polanco

10/10 Excellent

"Very nice place to stay. I highly recommend."

Hyatt Regency Mexico City

10/10 Excellent

"Desayuno muy variado y personal muy atento."

Krystal Satélite María Bárbara

8/10 Good

"This property has a lot of potential. It's beautiful. We had to request the coffee maker for our room. The safe instructions were worn off so we couldn't figure it out. Our biggest problem was the restaurant in the evening. They were obviously short staffed. A meal that should have taken an hour at the most was a 2 hour ordeal. With steaks cooked overdone. No I didn't send it back. Our table mates meals were served after ours and her potatoes were cold. When the, waiter was told. Nothing was done to compensate. The weekend brunches were amazing."

Downtown Treasure Place

10/10 Excellent

"Todo muy bien! Muy limpio todo, un lugar muy acogedor lo recomiendo mucho."

District Polanco by Lumina

10/10 Excellent

"BUENA ZONA, LIMPIEZA, COMODIDAD Y ATENCION"

Frequently asked questions

What accommodations do travelers like in Santa Cruz?

La Morada Tepotzotlan Boutique & Spa and Hotel Finca Las Hortensias are a couple of accommodations that are popular with guests.

Can I book refundable hotels in Santa Cruz?

If you want the flexibility to change your travel plans to Santa Cruz, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Santa Cruz be like during my vacation?

April and May are typically the warmest months in Santa Cruz when the average temp is 64°F. January and December are the coldest months when the average temperature is 57°F. August and July are the months with the most rain.

Why should I book my Santa Cruz accommodation with Hotels.com?

There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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