Hotels in Effingham

Q: What accommodations do travelers like in Effingham?

Guests like Comfort Inn & Suites Florence Center Area , Hyatt Place Florence Downtown and Aloft by Marriott Florence .

Where to?

Dates

November 2026

December 2026

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Where to stay in Effingham?

A hotel lobby with a reception desk, seating area, and a television screen.

1. Comfort Inn & Suites Florence Center Area

Florence

$113 total

includes taxes & fees

Nov 30 - Dec 1

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

2. Park Inn by Radisson Florence, SC

Florence

$101 total

includes taxes & fees

Nov 15 - Nov 16

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

3. Hyatt Place Florence Downtown

Florence

$130 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel with a covered entrance, large windows, and a sign indicating it is a hotel.

4. Aloft by Marriott Florence

Florence

$113 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

5. TownePlace Suites by Marriott Florence

Florence

$123 total

includes taxes & fees

Nov 10 - Nov 11

A multi-story hotel with a prominent entrance and signage for Springhill Suites by Marriott.

6. SpringHill Suites by Marriott Florence

Florence

$121 total

includes taxes & fees

Nov 12 - Nov 13

A hotel room with a desk, a bed, a sofa, a TV, and a mirror.

7. Quality Inn & Suites Florence Civic Center

Florence

$100 total

includes taxes & fees

Nov 16 - Nov 17

A restaurant with brick walls, framed awards, and a bar area.

8. Hotel Florence, Tapestry Collection by Hilton

Florence

$155 total

includes taxes & fees

Nov 20 - Nov 21

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

9. Howard Johnson by Wyndham Florence

Florence

$72 total

includes taxes & fees

Nov 10 - Nov 11

A hotel entrance with a covered walkway, columns, and a number '340' sign.

10. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Florence

$128 total

includes taxes & fees

Nov 15 - Nov 16

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

11. Hampton Inn & Suites Florence Center

Florence

$128 total

includes taxes & fees

Nov 22 - Nov 23

A hotel entrance with a covered walkway, a brick pathway, and a well-maintained garden.

12. Staybridge Suites Florence - Civic Center by IHG

Florence

$137 total

includes taxes & fees

Dec 6 - Dec 7

A hotel entrance with a stone facade, glass doors, and a number '501' above.

13. Fairfield Inn & Suites by Marriott Florence I-20

Florence

$132 total

includes taxes & fees

Nov 12 - Nov 13

A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

14. Residence Inn Marriott Florence

Florence

$120 total

includes taxes & fees

Nov 15 - Nov 16

A spacious room with a large window, a kitchenette, and two chairs.

15. Florence Inn and Suites

Florence

$59 total

includes taxes & fees

Nov 12 - Nov 13

A spacious lobby with a reception desk, seating area, and large windows.

16. Hilton Garden Inn Florence

Florence

$128 total

includes taxes & fees

Nov 15 - Nov 16

A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

17. Spark by Hilton Florence North I-95, SC

Florence

$114 total

includes taxes & fees

Nov 16 - Nov 17

An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.

18. Homewood Suites by Hilton Florence

Florence

$116 total

includes taxes & fees

Nov 23 - Nov 24

19. Home2 Suites by Hilton Florence, SC

Florence

$134 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a checkered sofa, a bed, a desk, and a framed picture on the wall.

20. Best Western Inn

Florence

$88 total

includes taxes & fees

Nov 11 - Nov 12

View all properties

Go beyond your typical stay in Effingham

Check out reviews of Effingham hotels guests love

Staybridge Suites Florence - Civic Center by IHG

Florence

10/10 Exceptional

William

Comfort Inn & Suites Florence Center Area

Florence

10/10 Exceptional

Roland

TownePlace Suites by Marriott Florence

Florence

10/10 Exceptional

Celia

Fairfield Inn & Suites by Marriott Florence I-20

Florence

10/10 Exceptional

Anonymous traveler

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Florence

10/10 Exceptional

Tammie

Park Inn by Radisson Florence, SC

Florence

10/10 Exceptional

Nichole

Hampton Inn & Suites Florence Center

Florence

10/10 Exceptional

Shawn

Residence Inn Marriott Florence

Florence

10/10 Exceptional

Staff were friendly and nice! Very accommodating to both my dogs. Room was clean and nice. Some wallpaper was bubbling but it honestly didn’t bother me. Loved the secure easy access to the building. Hotel was right next to a beautiful memorial park and very easy to get to the civic center. Pool was beautiful even though I didn’t get to use it due to weather. Looked like the pool was handicap accessible with a lift. Breakfast was amazing every morning with lots to choose from. We definitely will...

Anna

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

Hampton Inn & Suites Florence-North-I-95

Florence

10/10 Exceptional

I chose Hampton Inn in Florence because, overall, in the past I have had excellent experiences with this chain. I was very pleasantly treated to a very beautifully appointed hotel setting, it was also very clean. I saw staff picking up small items or pieces of paper that had been left or dropped by a visitor. My room itself was very clean and the bed was very comfortable and the room had it's own thermostat so the temperature and whether you wished heat or air could be selected for...

Anonymous traveler

Aloft by Marriott Florence

Florence

10/10 Exceptional

Kyle

Howard Johnson by Wyndham Florence

Florence

10/10 Exceptional

Mike

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

Tru by Hilton Florence I-95

Florence

10/10 Exceptional

Robert

A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.

Affordable Suites Florence

Florence

10/10 Exceptional

MY CL

Quality Inn & Suites Florence Civic Center

Florence

10/10 Exceptional

Jay

Frequently Asked Questions

What accommodations do travelers like in Effingham?

Guests like Comfort Inn & Suites Florence Center Area, Hyatt Place Florence Downtown and Aloft by Marriott Florence.

Can I book refundable accommodations in Effingham?

If you need the flexibility to change your plans to Effingham, most properties offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Effingham be like during my trip?

July and August are typically the warmest months in Effingham when the average temp is 78°F. January and February are the coldest months when the average temperature is 50°F. August and July are the months with the most rain.

Why should I book my Effingham accommodation with Hotels.com?

There are lots of reasons to book your Effingham trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.