Hotels in Santa María

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Next weekend
In two weeks

Where to stay in Santa María?

Hotel Estelar Playa Manzanillo
Hotel Estelar Playa Manzanillo
4.0 star property
Zona Norte
8.2 out of 10, Very Good, (960 reviews)
The price is $300
$300 total
Apr 5 - Apr 6
Hotel Estelar Playa Manzanillo
Sonesta Hotel Cartagena
Sonesta Hotel Cartagena
4.0 star property
La Boquilla
8.0 out of 10, Very Good, (1,006 reviews)
The price is $133
$133 total
Apr 6 - Apr 7
Sonesta Hotel Cartagena
Holiday Inn Cartagena Morros by IHG
Holiday Inn Cartagena Morros by IHG
4.0 star property
La Boquilla
8.8 out of 10, Excellent, (1,007 reviews)
  • cleanliness
    Oceanfront escape with spectacular garden views and Caribbean windsurfing nearby.
The price is $149
$149 total
Apr 5 - Apr 6
Holiday Inn Cartagena Morros by IHG
Radisson Cartagena Ocean Pavillion Hotel
Radisson Cartagena Ocean Pavillion Hotel
4.5 star property
La Boquilla
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Beach resort with Caribbean dining, outdoor pool, and spa services on offer.
The price is $207
$207 total
Mar 16 - Mar 17
Radisson Cartagena Ocean Pavillion Hotel
Faranda Collection Cartagena, a member of Radisson Individuals
Faranda Collection Cartagena, a member of Radisson Individuals
3.0 star property
La Boquilla
9.6 out of 10, Exceptional, (15 reviews)
The price is $152
$152 total
Apr 6 - Apr 7
Faranda Collection Cartagena, a member of Radisson Individuals
Hotel Las Americas Torre del Mar
Hotel Las Americas Torre del Mar
4.5 star property
La Boquilla
9.0 out of 10, Wonderful, (1,003 reviews)
The price is $194
$194 total
Mar 24 - Mar 25
Hotel Las Americas Torre del Mar
Las Americas Casa de Playa
Las Americas Casa de Playa
4.0 star property
La Boquilla
8.8 out of 10, Excellent, (1,001 reviews)
  • cleanliness
    Beachfront bliss with calm waves and dual pools in Cartagena awaits your escape.
The price is $161
$161 total
Apr 5 - Apr 6
Las Americas Casa de Playa
Hotel Summer Frente Al Mar
Hotel Summer Frente Al Mar
3.0 star property
La Boquilla
8.2 out of 10, Very Good, (587 reviews)
  • cleanliness
    Relax at a beachfront hotel with a rooftop terrace and poolside bar in Cartagena.
Hotel Summer Frente Al Mar
Hotel Zuriel Boutique
Hotel Zuriel Boutique
3.0 star property
Marbella
9.2 out of 10, Wonderful, (132 reviews)
  • cleanliness
    Immerse in local charm within 15 minutes of Cartagena's iconic Clock Tower.
The price is $76
$76 total
Mar 12 - Mar 13
Hotel Zuriel Boutique
Varanasi Hotel Boutique
Varanasi Hotel Boutique
3.0 star property
Marbella
9.2 out of 10, Wonderful, (605 reviews)
  • cleanliness
    Boutique oasis with pool and terrace near Cartagena's Clock Tower and beaches.
Varanasi Hotel Boutique
Hotel Ayenda Casa Cano 1805
Hotel Ayenda Casa Cano 1805
3.0 star property
Marbella
8.2 out of 10, Very Good, (224 reviews)
  • cleanliness
    Vibrant Cartagena hotel within minutes of the historic Clock Tower and beaches.
The price is $60
$60 total
Mar 14 - Mar 15
Hotel Ayenda Casa Cano 1805
Múcura Hotel & Spa
Múcura Hotel & Spa
3.0 star property
Marbella
8.4 out of 10, Very Good, (98 reviews)
  • cleanliness
    Tropical bliss near historic Cartagena with spa treatments and garden views.
The price is $67
$67 total
Mar 26 - Mar 27
Múcura Hotel & Spa
Wyndham Garden Cartagena
Wyndham Garden Cartagena
3.5 star property
Marbella
8.6 out of 10, Excellent, (1,418 reviews)
  • cleanliness
    Modern Cartagena stay with pool, fitness center, and 2 bars minutes from Clock Tower.
The price is $104
$104 total
Mar 8 - Mar 9
Wyndham Garden Cartagena
GHL Corales de Indias
GHL Corales de Indias
4.0 star property
Marbella
8.0 out of 10, Very Good, (1,002 reviews)
The price is $119
$119 total
Mar 24 - Mar 25
GHL Corales de Indias
Holiday Inn Express Cartagena Manga by IHG
Holiday Inn Express Cartagena Manga by IHG
3.5 star property
Manga
8.6 out of 10, Excellent, (244 reviews)
  • cleanliness
    Waterfront relaxation with free breakfast just minutes from Cartagena's historic center.
The price is $114
$114 total
Mar 23 - Mar 24
Holiday Inn Express Cartagena Manga by IHG
Bondo Estudio
Bondo Estudio
3.5 star property
Marbella
9.2 out of 10, Wonderful, (718 reviews)
  • cleanliness
    Beach getaway with rooftop terrace and two pools minutes from Clock Tower.
The price is $80
$80 total
Mar 8 - Mar 9
Bondo Estudio
ibis Cartagena Marbella
ibis Cartagena Marbella
3.0 star property
Marbella
8.2 out of 10, Very Good, (1,010 reviews)
  • cleanliness
    Seaside convenience just minutes from Rafael Nunez Airport with easy shuttle service.
The price is $54
$54 total
Mar 24 - Mar 25
ibis Cartagena Marbella
Hotel El Marques de Manga
Hotel El Marques de Manga
3.0 star property
Manga
8.8 out of 10, Excellent, (67 reviews)
  • cleanliness
    Tropical retreat minutes from Cartagena's Clock Tower with refreshing pool access.
Hotel El Marques de Manga
Hotel Fenix Beach Cartagena
Hotel Fenix Beach Cartagena
4.0 star property
Cartagena
8.8 out of 10, Excellent, (633 reviews)
  • cleanliness
    Experience beachfront bliss with private cabanas and rooftop views at this coastal retreat.
The price is $136
$139 total
Apr 7 - Apr 8
Hotel Fenix Beach Cartagena
GHL San Lazaro Art Hotel
GHL San Lazaro Art Hotel
4.0 star property
Pie del Cerro
9.2 out of 10, Wonderful, (965 reviews)
  • cleanliness
    Discover a colorful retreat steps from Clock Tower and Bocagrande Beach.
The price is $133
$133 total
Mar 31 - Apr 1
GHL San Lazaro Art Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check out reviews of Santa María hotels guests love

Frequently asked questions

What hotels do travelers recommend in Santa María?
Can I book a refundable hotel in Santa María?
If you need the flexibility to change your plans to Santa María, most properties provide refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Santa María be like during my vacation?
With an average temperature of 82°F during the coldest months, Santa María is a great place to visit any time of year.
Why should I book my Santa María hotel with Hotels.com?
There are plenty of reasons to book your Santa María travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.