Photo by Mikey

Hotels in Clayton

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Check prices for these dates

Tonight
Nov 6 - Nov 7
Tomorrow
Nov 7 - Nov 8
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Where to stay in Clayton?

A bedroom with a canopy bed, bedside tables, and a framed picture on the wall.

1. The Cotton Mill Hideaway

The Cotton Mill Hideaway
3.0 star property
Manchester
10.0 out of 10, Exceptional, (1 review)
The price is $157
$188 total
includes taxes & fees
Dec 6 - Dec 7
The Cotton Mill Hideaway
Meeting facility

2. Radisson Blu Medlock Hotel, Manchester

Radisson Blu Medlock Hotel, Manchester
4.0 star property
Bradford
9.2 out of 10, Wonderful, (118 reviews)
The price is $101
$121 total
includes taxes & fees
Nov 15 - Nov 16
Radisson Blu Medlock Hotel, Manchester
A modern hotel reception area with a white reception desk, two computers, and a large green plant. There are two sofas and a coffee table in the background.

3. Leonardo Hotel Manchester Piccadilly

Leonardo Hotel Manchester Piccadilly
4.0 star property
Manchester City Centre
9.0 out of 10, Wonderful, (1,703 reviews)
Immerse in Manchester's vibrant culture from this modern hotel near Canal Street and Piccadilly Gardens. After exploring nearby O2 Apollo or Etihad Stadium, unwind with a meal at the Bar and Grill or visit the fitness center for a workout.
The price is $78
$95 total
includes taxes & fees
Nov 29 - Nov 30
Leonardo Hotel Manchester Piccadilly
A modern living room with a sectional sofa, multiple chairs, a TV, and a bookshelf.

4. Residence Inn by Marriott Manchester Piccadilly

Residence Inn by Marriott Manchester Piccadilly
4.0 star property
Manchester City Centre
9.0 out of 10, Wonderful, (1,000 reviews)
Experience Manchester's energy from this centrally located hotel with Canal Street and Piccadilly Gardens just a 10-minute walk away. Enjoy free continental breakfast, WiFi, and a 24-hour fitness center while being minutes from New Islington Tram Stop.
The price is $90
$109 total
includes taxes & fees
Nov 23 - Nov 24
Residence Inn by Marriott Manchester Piccadilly
A modern hotel lobby with a seating area, a reception desk, and a wall with decorative elements.

5. Motel One Manchester-Piccadilly

Motel One Manchester-Piccadilly
3.5 star property
Manchester City Centre
9.2 out of 10, Wonderful, (1,947 reviews)
Just a 1-minute walk from Manchester Piccadilly Station, this hotel offers comfortable beds and a stylish bar/lounge. Explore Canal Street and Piccadilly Gardens within 10 minutes, or catch a quick drive to University of Manchester and O2 Apollo.
The price is $70
$85 total
includes taxes & fees
Nov 15 - Nov 16
Motel One Manchester-Piccadilly
A modern hotel with a curved facade, multiple floors, and illuminated windows.

6. Manchester Marriott Hotel Piccadilly

Manchester Marriott Hotel Piccadilly
4.0 star property
Manchester City Centre
9.0 out of 10, Wonderful, (1,503 reviews)
Nestled between Canal Street and Piccadilly Gardens, this hotel offers a full-service spa with deep-tissue massages and facials. Enjoy local cuisine at Loom & Ladle or drinks at the bar after exploring Manchester's attractions just a short walk away.
The price is $104
$127 total
includes taxes & fees
Nov 29 - Nov 30
Manchester Marriott Hotel Piccadilly
A modern hotel building with a prominent sign for Holiday Inn Express.

7. Holiday Inn Express Manchester City Centre Arena by IHG

Holiday Inn Express Manchester City Centre Arena by IHG
3.0 star property
Manchester City Centre
8.6 out of 10, Excellent, (1,408 reviews)
Wake up to a free buffet breakfast at this Manchester city center hotel, just minutes from Shudehill Station. A bar/lounge provides evening refreshments, while AO Arena and Canal Street are both within a 15-minute stroll. Helpful staff enhance your stay.
The price is $71
$87 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express Manchester City Centre Arena by IHG
A room with two beds, a brick wall, large windows, and a hanging garment rack.

8. easyHotel Manchester

easyHotel Manchester
2.0 star property
Manchester City Centre
8.0 out of 10, Very good, (1,002 reviews)
This modern hotel puts you steps from Piccadilly Gardens and Canal Street, with Deansgate and AO Arena just a 15-minute walk away. Enjoy free WiFi and 24-hour front desk service while staying in clean, comfortable rooms near Manchester's top attractions.
The price is $46
$57 total
includes taxes & fees
Nov 29 - Nov 30
easyHotel Manchester
A modern interior with large windows, seating areas, and a patterned carpet.

9. Holiday Inn Manchester - City Centre by IHG

Holiday Inn Manchester - City Centre by IHG
4.0 star property
Manchester City Centre
9.2 out of 10, Wonderful, (1,932 reviews)
Modern accommodation in Manchester's heart, just 4 minutes from Piccadilly Gardens Station. Guests love the hearty breakfast and attentive staff. Enjoy the fitness center, terrace, and bar after exploring Canal Street or catching a train at Manchester Piccadilly.
The price is $98
$119 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Manchester - City Centre by IHG
A modern living room with a red sofa, yellow armchair, and a wooden partition with vertical slats.

10. Holiday Inn - the niu, Loom Manchester North by IHG

Holiday Inn - the niu, Loom Manchester North by IHG
3.0 star property
Manchester
9.0 out of 10, Wonderful, (1,161 reviews)
This modern Manchester hotel offers quick access to top attractions like Old Trafford and Piccadilly Gardens. Enjoy drinks at the bar/lounge, grab bites at the café, and appreciate the 6-minute walk to Queens Road Tram Stop for easy city exploration.
The price is $56
$82 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn - the niu, Loom Manchester North by IHG
A bustling square with traditional half-timbered buildings, outdoor seating at a pub, and a prominent clock tower.

11. Crowne Plaza Hotel Manchester City Centre by IHG

Crowne Plaza Hotel Manchester City Centre by IHG
4.0 star property
Manchester City Centre
9.0 out of 10, Wonderful, (1,007 reviews)
Minutes from Piccadilly Gardens and Deansgate, this hotel offers 24-hour fitness and room service. Enjoy breakfast at Glasshouse restaurant or unwind at the bar. Just 3 minutes from Shudehill Station with Old Trafford nearby, guests love the clean rooms and helpful staff.
The price is $89
$108 total
includes taxes & fees
Nov 22 - Nov 23
Crowne Plaza Hotel Manchester City Centre by IHG
A modern reception area with a desk, chairs, and a large potted plant.

12. Maldron Hotel Manchester City Centre

Maldron Hotel Manchester City Centre
4.0 star property
Manchester City Centre
9.0 out of 10, Wonderful, (1,683 reviews)
Unwind at this Manchester hotel with easy access to Canal Street and Piccadilly Gardens. Enjoy breakfast at Grain & Grill restaurant before exploring nearby Old Trafford. The fitness center keeps your routine on track while free WiFi keeps you connected.
The price is $79
$97 total
includes taxes & fees
Dec 6 - Dec 7
Maldron Hotel Manchester City Centre
A modern building with a curved glass facade and the 'StayCity' sign prominently displayed.

13. Staycity Aparthotels, Manchester, Piccadilly

Staycity Aparthotels, Manchester, Piccadilly
4.0 star property
Manchester City Centre
9.2 out of 10, Wonderful, (1,001 reviews)
Explore Manchester from these modern apartments near Canal Street and Picadilly Gardens. Each unit features a full kitchen, washer/dryer, and espresso maker. The fitness center, coffee shop, and bar provide additional comforts just minutes from public transit.
The price is $109
$133 total
includes taxes & fees
Nov 15 - Nov 16
Staycity Aparthotels, Manchester, Piccadilly
A grand staircase with ornate railings and a large chandelier, leading to a high-ceilinged lobby with columns and a patterned floor.

14. Britannia Hotel Manchester

Britannia Hotel Manchester
3.0 star property
Manchester City Centre
7.0 out of 10, Good, (2,232 reviews)
Vibrant energy flows through this Manchester hotel, just steps from Piccadilly Gardens and Canal Street. With 2 restaurants, 2 bars, and a nightclub, you're perfectly positioned to explore with Old Trafford nearby and Manchester Piccadilly Station a 7-minute walk away.
The price is $46
$57 total
includes taxes & fees
Dec 6 - Dec 7
Britannia Hotel Manchester
An outdoor patio with round tables and chairs, surrounded by lush greenery and a large tree.

15. Dakota Manchester

Dakota Manchester
4.5 star property
Manchester City Centre
9.6 out of 10, Exceptional, (1,002 reviews)
The price is $161
$194 total
includes taxes & fees
Nov 15 - Nov 16
Dakota Manchester
A spacious lobby with a large mirror, a seating area with a sofa and armchairs, and a view into a restaurant or dining area.

16. Manchester Portland By Sunday

Manchester Portland By Sunday
3.5 star property
Manchester City Centre
8.4 out of 10, Very good, (1,896 reviews)
The price is $68
$83 total
includes taxes & fees
Nov 15 - Nov 16
Manchester Portland By Sunday
A modern hotel with a prominent 'Famous' sign on the facade, multiple floors, and a street view with a clear sky.

17. Hampton by Hilton Manchester City, Northern Quarter

Hampton by Hilton Manchester City, Northern Quarter
3.5 star property
Manchester
8.6 out of 10, Excellent, (1,000 reviews)
The price is $85
$103 total
includes taxes & fees
Nov 22 - Nov 23
Hampton by Hilton Manchester City, Northern Quarter
A large, historic building with a prominent corner entrance, multiple windows, and a central tower.

18. Malmaison Manchester

Malmaison Manchester
4.0 star property
Manchester City Centre
9.0 out of 10, Wonderful, (1,237 reviews)
Tucked into Manchester's heart with spa services and a fitness center, this hotel puts you steps from public transport. Grab a cocktail at the stylish bar, then wander to nearby Old Trafford or the Trafford Centre.
The price is $81
$99 total
includes taxes & fees
Nov 29 - Nov 30
Malmaison Manchester
A modern indoor space with multiple seating areas, including round tables and chairs, surrounded by potted plants.

19. Aloft by Marriott Manchester City Centre

Aloft by Marriott Manchester City Centre
3.5 star property
Manchester City Centre
8.6 out of 10, Excellent, (104 reviews)
The price is $75
$92 total
includes taxes & fees
Nov 16 - Nov 17
Aloft by Marriott Manchester City Centre
A building with a sign reading 'MOLLIE'S BAR & DINER' and a large illuminated 'MOLLIE'S' sign on the side.

20. Mollie's Manchester

Mollie's Manchester
4.0 star property
Manchester City Centre
9.6 out of 10, Exceptional, (265 reviews)
The price is $110
$132 total
includes taxes & fees
Nov 15 - Nov 16
Mollie's Manchester
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in Clayton

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Pet friendly
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Hot tub
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Top landmarks in Clayton

National Cycling Centre

8.0/10 (3 reviews)
You can catch an event at National Cycling Centre, located 2.3 mi (3.6 km) from central Clayton. Our travelers also like the museums in the area— your cultural tour starts here. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. If you think National Cycling Centre is cool, you also might like Old Trafford and Co-op Live Arena, both located nearby.
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Learn more about Clayton

Clayton is well-known for its attractions such as National Cycling Centre and Manchester Velodrome.

See all hotels in Clayton
A Tudor-style house with a garden, parked cars, and a 'KEEP LEFT' sign.
Photo by Mikey
Open Photo by Mikey

Check out reviews of Clayton hotels guests love

Meeting facility
Radisson Blu Medlock Hotel, Manchester

Radisson Blu Medlock Hotel, Manchester

Radisson Blu Medlock Hotel, Manchester
Bradford

10/10 Exceptional

The room was clean and the bed was comfortable. The staff were friendly and helpful. The only negatives were the restaurant closed early and parking was inconvenient. I believe the restaurant will have later hours as the hotel builds their location. The parking would have been better if I wasn’t arriving on a game night. We had to park across the lot and walk through the mud with our bags.
United States
Catherine
Reviewed September 21, 2026
Radisson Blu Medlock Hotel, Manchester

Frequently Asked Questions

What accommodations do travelers like in Clayton?

Guests like TRIBE Manchester Airport, The Alan and a&o Manchester City Centre.

Can I book refundable hotels in Clayton?

If you want the flexibility to change your travel plans to Clayton, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Clayton if I want a vacation home instead of a hotel?

If you want to find a good alternative to a hotel, look over our selection of 32 vacation homes. In addition, you can choose from 14 apartments.

What will the weather in Clayton be like during my trip?

July and August are typically the warmest months in Clayton when the average temp is 59°F. January and February are the coldest months when the average temperature is 41°F. December and July are the months with the most rain.

Why should I book my Clayton accommodation with Hotels.com?

There are lots of reasons to book your Clayton trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.