Top 10 Hotels in Essex, MO in 2026 (from $49)

Q: What hotels do travelers like in Essex?

Guests like Hampton Inn By Hilton Dexter , Dexter Inn and Econo Lodge Dexter .

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Where to stay in Essex?

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

1. Econo Lodge Dexter

Dexter

$58 total

includes taxes & fees

Dec 10 - Dec 11

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

2. Dexter Inn

Dexter

$78 total

includes taxes & fees

Nov 13 - Nov 14

A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

3. OYO Hickory House Inn

Dexter

$72 total

includes taxes & fees

Nov 13 - Nov 14

A diner with booth seating, a checkered floor, and a counter with a cash register.

4. Travelodge by Wyndham Dexter

Dexter

$98 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel lobby with a central dining area, a minibar, and a view of the outdoors.

5. Hampton Inn By Hilton Dexter

Dexter

$111 total

includes taxes & fees

Nov 22 - Nov 23

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

6. Hampton Inn Sikeston

Sikeston

$115 total

includes taxes & fees

Nov 19 - Nov 20

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

7. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

$125 total

includes taxes & fees

Nov 19 - Nov 20

A buffet with various food items, including omelets and baked goods, served in metal containers.

8. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

$108 total

includes taxes & fees

Dec 13 - Dec 14

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

9. Drury Inn & Suites Sikeston, MO

Sikeston

$108 total

includes taxes & fees

Nov 22 - Nov 23

10. TownePlace Suites by Marriott Sikeston

Sikeston

$124 total

includes taxes & fees

Nov 19 - Nov 20

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

11. Best Western Plus Sikeston I-55

Sikeston

$83 total

includes taxes & fees

Dec 7 - Dec 8

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

12. Country Yard Inn and Suite

Sikeston

$70 total

includes taxes & fees

Nov 13 - Nov 14

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

13. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

$66 total

includes taxes & fees

Nov 17 - Nov 18

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

14. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

$79 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

15. Days Inn and Suites by Wyndham Sikeston

Sikeston

$76 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

16. Super 8 By Wyndham Marston

Marston

$66 total

includes taxes & fees

Nov 14 - Nov 15

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

17. Comfort Inn & Suites Sikeston I-55

Sikeston

$96 total

includes taxes & fees

Nov 22 - Nov 23

A hotel lobby with a glass table and checkered chairs, an exit door, and a vending machine.

18. Travel Inn Marston I-55 by Hotel O

Marston

$61 total

includes taxes & fees

Dec 2 - Dec 3

A bedroom with a bed, bedside table, lamp, and a view of the bathroom.

19. OYO Malden Airport Inn

Malden

View all properties

Go beyond your typical stay in Essex

Check out reviews of Essex hotels guests love

Drury Inn & Suites Sikeston, MO

Sikeston

10/10 Exceptional

Judy

Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

10/10 Exceptional

Anonymous traveler

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

10/10 Exceptional

Anonymous traveler

Best Western Plus Sikeston I-55

Sikeston

10/10 Exceptional

Anonymous traveler

Comfort Inn & Suites Sikeston I-55

Sikeston

10/10 Exceptional

This is a fantastic hotel! The staff is very wonderful and helpful and thoughtful when my father passed away in November of 2017, part of my family stayed at this hotel. Now I am back here waiting for my mother to arrive for we are going to finally get to see my father who was a Vietnam veteran and was buried at the Bloomfield Cemetery has his headstone put up anyhow I have had some difficulties with a lot of the hotels around here in this one is by far the best I would recommend it to anyone.

Anonymous traveler

Frequently Asked Questions

What hotels do travelers like in Essex?

Guests like Hampton Inn By Hilton Dexter, Dexter Inn and Econo Lodge Dexter.

Can I book refundable accommodations in Essex?

If you need the flexibility to change your travel plans to Essex, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Essex be like during my vacation?

The warmest months in Essex are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.

Why should I book my Essex hotel through Hotels.com?

There are plenty of reasons to book your Essex travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.