Hotels in Mayo

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Where to stay in Mayo?

A hotel room with a bed, a blue sofa, a wooden coffee table, a desk with a chair, and a framed abstract painting on the wall.

A Holiday Inn Express & Suites hotel with a covered entrance and multiple stories.

A large indoor swimming pool with a diving board, multiple doors, and seating areas.

A hotel reception area with a modern design, featuring a reception desk, two seating areas with chairs, and a wall-mounted artwork.

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Spartanburg

$95

$106 total

includes taxes & fees

Oct 4 - Oct 5

A conference room with a long table, blue and orange chairs, and a reception desk in the background.

A coffee station with labeled dispensers for hot water, decaf roast, light roast, and dark roast coffee.

A gym with treadmills, elliptical machines, and weight machines.

A Hampton Inn hotel with a clear entrance, well-maintained lawn, and a flagpole.

Hampton Inn Spartanburg-North I-85

Spartanburg

$107

$118 total

includes taxes & fees

Oct 1 - Oct 2

A hotel dining area with multiple tables and chairs, a television mounted on a wall, and a kitchen area visible in the background.

A hotel with a swimming pool, lounge chairs, and a covered seating area.

A Sleep Inn hotel entrance with a clear sky, a flagpole, and a parking lot.

A living room with a sofa, two armchairs, a coffee table, and a patterned rug.

Sleep Inn Gaffney at I-85

Gaffney

$67

$75 total

includes taxes & fees

Sep 22 - Sep 23

A modern lobby with a blue sofa, a reception desk, and a large cityscape painting.

A modern restaurant with a bar area, large windows, and a kitchen visible in the background.

A hotel room with two beds, a nightstand, and a wall-mounted TV.

A Best Western Plus hotel with a parking lot and multiple cars parked in front.

Best Western Plus Spartanburg

Spartanburg

$91

$103 total

includes taxes & fees

Sep 6 - Sep 7

A lobby with a leather sofa, two lamps, a painting, and potted plants.

A swimming pool with a brick border and a metal ladder, surrounded by a fence and a house in the background.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom visible through an open door.

A hotel lobby with a reception desk, a waiting area with a chair, and a large window providing a view of the outside.

Quality Inn Gaffney I-85

Gaffney

$50

$56 total

includes taxes & fees

Sep 27 - Sep 28

A modern lobby with a reception desk, seating area, and a television screen.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.

Best Western Spartanburg I-26

Spartanburg

$89

$99 total

includes taxes & fees

Sep 9 - Sep 10

A hotel room with a bed, a TV, a desk, and a microwave.

A hotel with a parking lot and a covered walkway.

A restaurant with red chairs and a counter with food items.

A hotel reception area with a digital sign indicating free Wi-Fi availability.

Red Roof Inn Gaffney

Gaffney

$62

$70 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with a bed, a desk with a computer, a television, and a microwave.

A single-story motel with a flat roof, large windows, and a small porch area.

A room with two beds, each with a wooden headboard and a floral bedspread. There is a small wooden table beside the beds.

A bathroom with a bathtub, shower curtain, and marble wall tiles.

SUN AND SAND MOTEL

Spartanburg

$72

$80 total

includes taxes & fees

Oct 2 - Oct 3

A modern reception area with a counter, seating, and a bookshelf with various items.

A clinical setting with medical equipment, a large mirror, and a window providing natural light.

A multi-story hotel with a stone facade and multiple windows, featuring a parking lot and landscaped areas.

A swimming pool with a metal ladder, surrounded by red chairs and umbrellas, with a building in the background.

Holiday Inn Spartanburg Northwest by IHG

Spartanburg

$97

$108 total

includes taxes & fees

Sep 6 - Sep 7

University Inn

Shelby

$81

$92 total

includes taxes & fees

Sep 24 - Sep 25

A buffet with various food items, including omelets and cheese.

A reception desk with a modern design, a blue geometric wall pattern, and a wooden accent wall.

A hotel room with two beds, a desk, and a view of the outdoors.

A modern lobby with a sofa, chairs, a desk, and a map mural on the wall.

Holiday Inn Express Gaffney by IHG

Gaffney

$78

$85 total

includes taxes & fees

Sep 20 - Sep 21

A hotel lobby with a bar area, seating with patterned upholstery, and a central coffee table.

A hotel room with a large bed, a desk with a television, a chair, and a small table.

A hotel reception desk with a 'Welcome to the Palmetto State' sign, a 'Manager On Duty' sign, and a 'Hilton Honors' sign.

A fitness center with treadmills, a bench, and exercise equipment.

Hampton Inn Gaffney

Gaffney

$118

$129 total

includes taxes & fees

Sep 12 - Sep 13

A hotel lobby with a reception desk, green sofa, patterned armchairs, and a potted plant.

A swimming pool with lounge chairs, a lifeguard station, and a multi-story building with balconies.

A hotel room with a bed, desk, chair, television, and lamps.

A motel with multiple rooms, a blue awning, and a red car parked in front.

Baymont by Wyndham Gaffney

Gaffney

$70

$78 total

includes taxes & fees

Sep 7 - Sep 8

A hotel room with two beds, a desk, a refrigerator, a television, and a bathroom visible through an arched doorway.

A modern bathroom with a large bathtub, a chair, and a floor lamp.

A hotel kitchen with a buffet setup, including a coffee station, a refrigerator, and a microwave.

A hotel with a well-lit entrance, multiple parking spaces, and a clear view of the sky.

Comfort Inn & Suites Spartanburg North

Spartanburg

$84

$93 total

includes taxes & fees

Sep 27 - Sep 28

A modern bedroom with a large bed, a built-in TV, and a small desk.

A motel with multiple floors, balconies, and a parking lot.

A reception area with a modern design, including a large number '6' sign, a coffee machine, and a TV mounted on the wall.

A laundry room with three stacked washing machines, a power outlet, and a water heater.

Motel 6 Spartanburg, Sc – Northwest / Business 85

Spartanburg

$58

$64 total

includes taxes & fees

Oct 4 - Oct 5

A modern living room with a fireplace, two sofas, and a coffee table.

A hotel lobby with multiple seating areas, a reception desk, and a fireplace.

A hotel room with two beds, a desk, a TV, and a window with curtains.

A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.

Best Western Spartanburg Northwest

Spartanburg

$93

$105 total

includes taxes & fees

Sep 6 - Sep 7

Red Roof Inn Spartanburg - I-85

Spartanburg

$58

$64 total

includes taxes & fees

Sep 15 - Sep 16

A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.

A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.

A modern kitchen with marble countertops, wooden shelves, and a wine station.

A spacious lobby with a high ceiling, chandeliers, a registration desk, and potted plants.

Spartanburg Marriott

Spartanburg

$118

$131 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with a bed, desk, chair, TV, and a painting on the wall.

A reception area with a wooden reception desk, a blue sofa, a small table with a lamp, and a window with curtains.

A room with two blue leather sofas, a glass coffee table, and floral curtains.

A conference room with rows of blue chairs, a carpeted floor, and a yellow wall.

Super 8 by Wyndham Gaffney

Gaffney

$54

$60 total

includes taxes & fees

Sep 15 - Sep 16

A modern kitchen with wooden cabinets, a built-in oven, and a coffee station.

A modern lobby with a large white reception desk, brown leather sofas, a round coffee table, and a ceiling light fixture.

A wooden gazebo with a metal roof, a bench, and a ramp leading up to it.

Days Inn by Wyndham Spartanburg

Boiling Springs

$79

$88 total

includes taxes & fees

Sep 7 - Sep 8

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Go beyond your typical stay in Mayo

Pet friendly

Pool

Family friendly

Check out reviews of Mayo hotels guests love

Tru by Hilton Spartanburg

10/10 Excellent

"Everything was great, as always. The snack bar was out of most items so that was disappointingand the front desk girl said they wouldn’t restock it until the next day."

Best Western Spartanburg Northwest

10/10 Excellent

"Everything was great ! At breakfast I noticed the desk clerk was not very friendly."

Four Points by Sheraton Spartanburg

10/10 Excellent

"Liked a large workout room. Furnishings were dated."

Spartanburg Marriott

10/10 Excellent

"From the first moment, we were impressed with the property. The common areas are clean. The registration representative was friendly and personable. All questions were answered. The room was clean with a great view. the location was perfect for our event. We went to see "Backbone" at the Chapman Cultural Arts center less than a mile away. The streets were quiet and we felt safe walking to and from the event after 9pm. Very happy with choice and will visit again."

ECHO Suites Extended Stay by Wyndham Spartanburg

8/10 Good

"Location was real good"

Days Inn by Wyndham Spartanburg Waccamaw

10/10 Excellent

"Affordable and price friendly"

Comfort Suites At WestGate Mall

8/10 Good

"None"

University Inn

8/10 Good

"N/A"

Hampton Inn Gaffney

10/10 Excellent

"The staff were very courteous and friendly. Our room was clean and comfortable. We slept well for about 9 hours!!! Before checking out we had breakfast. Hampton Inn has the best Breakfast Selection- #1 in our book!!! Keep up the great customer service! Awesome!!!!"

Frequently asked questions

What accommodations do travelers recommend in Mayo?

Guests like Holiday Inn Express Hotel & Suites Spartanburg-North by IHG, Best Western Spartanburg Northwest and Spartanburg Marriott.

Can I book a refundable hotel in Mayo?

If you're looking for the flexibility to change your plans to Mayo, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Mayo be like during my visit?

July and August are typically the warmest months in Mayo when the average temp is 77°F. January and February are the coldest months when the average temperature is 46°F. December and April are the months with the most rain.

Why should I book my Mayo accommodation with Hotels.com?

There are lots of reasons to book your Mayo trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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