Hotels in Mayo

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Where to stay in Mayo?

A conference room with a large table and chairs, large windows with a view of trees, and a flat-screen TV mounted on the wall.

A reception desk with a modern design, a blue geometric wall pattern, and a wooden accent wall.

A hotel room with two beds, a desk, and a view of the outdoors.

A vending area with Coca-Cola and Sprite refrigerated drinks, a 'happy place' sign, and snack baskets on shelves.

1. Holiday Inn Express Gaffney by IHG

Gaffney

$76

$83 total

includes taxes & fees

Nov 1 - Nov 2

A modern lobby with a blue sofa, a reception desk, and a large cityscape painting.

A hotel room with two beds, a nightstand, and a wall-mounted TV.

A modern restaurant with a bar area, large windows, and a kitchen visible in the background.

A Best Western Plus hotel with a parking lot and multiple cars parked in front.

2. Best Western Plus Spartanburg

Spartanburg

$87

$99 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a bar area, seating with patterned upholstery, and a central coffee table.

A fitness center with treadmills, a bench, and exercise equipment.

A snack and beverage vending area with various snacks and drinks.

A hotel room with a large bed, a desk with a television, a chair, and a small table.

3. Hampton Inn Gaffney

Gaffney

$99

$107 total

includes taxes & fees

Nov 3 - Nov 4

A hotel lobby with a reception desk, a staircase, and a seating area with chairs.

A living room with a sofa, two armchairs, a coffee table, and a patterned rug.

A hotel entrance with a covered walkway, a pool area, and a sign for a spa.

A hotel with a swimming pool, lounge chairs, and a covered seating area.

4. Sleep Inn Gaffney at I-85

Gaffney

$59

$66 total

includes taxes & fees

Nov 15 - Nov 16

A lobby with a reception desk, a clock, and an exit sign.

A multi-story building with a parking lot in front.

A hotel room with a large bed, a desk with a chair, a TV, and a window with curtains.

A clean, modern office space with vending machines, a coffee machine, and a trash can.

5. USA Economy Lodge

Spartanburg

A modern bedroom with a large bed, a built-in TV, and a small desk.

A reception area with a modern design, including a large number '6' sign, a coffee machine, and a TV mounted on the wall.

A motel with multiple floors, balconies, and a parking lot.

A laundry room with three stacked washing machines, a power outlet, and a water heater.

6. Motel 6 Spartanburg, Sc – Northwest / Business 85

Spartanburg

$58

$64 total

includes taxes & fees

Nov 11 - Nov 12

A hotel room with two beds, a desk, a chair, and a large window with autumn foliage artwork.

A hotel room with a wooden desk, a black chair, a small refrigerator, a microwave, and a TV on the wall.

A self-service coffee station with a Folgers Select Brew coffee maker and a vintage-themed beverage dispenser.

A hotel lobby with a registration desk, patterned sofas, and a ceiling fan.

7. Days Inn by Wyndham Spartanburg Waccamaw

Spartanburg

$60

$67 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a desk, a refrigerator, a television, and a bathroom visible through an arched doorway.

A hotel kitchen with a buffet setup, including a coffee station, a refrigerator, and a microwave.

A modern bathroom with a large bathtub, a chair, and a floor lamp.

A hotel with a well-lit entrance, multiple parking spaces, and a clear view of the sky.

8. Comfort Inn & Suites Spartanburg North

Spartanburg

$84

$93 total

includes taxes & fees

Nov 15 - Nov 16

A modern lobby with a reception desk, seating area, and a television screen.

A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.

A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

9. Best Western Spartanburg I-26

Spartanburg

$93

$103 total

includes taxes & fees

Nov 1 - Nov 2

A lobby with a leather sofa, two lamps, a painting, and potted plants.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom visible through an open door.

A dining area with a high ceiling, wooden chairs, a table, and a kitchen area with a TV and food display.

A swimming pool with a brick border and a metal ladder, surrounded by a fence and a house in the background.

10. Quality Inn Gaffney I-85

Gaffney

$47

$52 total

includes taxes & fees

Nov 22 - Nov 23

A Holiday Inn Express & Suites hotel with a covered entrance and multiple stories.

A hotel reception area with a modern design, featuring a reception desk, two seating areas with chairs, and a wall-mounted artwork.

A buffet with various food items, including omelets and other dishes, displayed in stainless steel chafing dishes.

A hotel room with a bed, a blue sofa, a wooden table, a lamp, and a framed abstract painting on the wall.

11. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Spartanburg

$114

$127 total

includes taxes & fees

Nov 1 - Nov 2

A multi-level hotel lobby with seating areas, a fireplace, and a staircase.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and wooden panel walls.

A modern hotel building with a large glass facade, a covered entrance, and a sign reading "Four Points by Sheraton".

A spacious lobby with a high ceiling, modern furniture, and large windows offering views of the outdoors.

12. Four Points by Sheraton Spartanburg

Spartanburg

$107

$119 total

includes taxes & fees

Nov 8 - Nov 9

A hotel reception area with a digital sign indicating free Wi-Fi availability.

A restaurant with red chairs and a counter with food items.

A hotel room with a bed, a TV, a desk, and a microwave.

13. Red Roof Inn Gaffney

Gaffney

$66

$74 total

includes taxes & fees

Nov 2 - Nov 3

A conference room with a long table, blue and orange chairs, and a reception desk in the background.

A coffee station with labeled dispensers for hot water, decaf roast, light roast, and dark roast coffee.

A gym with treadmills, elliptical machines, and weight machines.

A conference room with two desks, two chairs, and a small table.

14. Hampton Inn Spartanburg-North I-85

Spartanburg

$127

$141 total

includes taxes & fees

Nov 15 - Nov 16

A large brick building with multiple towers and a clock tower, featuring arched windows and a prominent steeple.

A bar area with a variety of liquor bottles, glasses, and a counter with food items.

A multi-story hotel with a stone facade and multiple windows, featuring a parking lot and landscaped areas.

15. Holiday Inn Spartanburg Northwest by IHG

Spartanburg

$101

$112 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a bar area, seating, and large windows.

A bar area with a long counter, multiple stools, and shelves stocked with bottles.

An outdoor seating area with string lights, tables, and chairs at the Hilton Garden Inn.

A hotel entrance with a covered walkway, a landscaped area with trees, and a well-lit building facade.

16. Hilton Garden Inn Spartanburg

Spartanburg

$115

$127 total

includes taxes & fees

Nov 15 - Nov 16

A wooden gazebo with a metal roof, a bench, and a ramp leading up to it.

A reception area with wooden reception desks, framed artwork, and a white door.

A modern lobby with a large white reception desk, brown leather sofas, a round coffee table, and a ceiling light fixture.

17. Days Inn by Wyndham Spartanburg

Boiling Springs

$77

$85 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.

A modern lobby with blue sofas, a reception desk, and a glass coffee table.

A hotel room with a bed, a gray sofa, two ottomans, a window with a view, and abstract artwork on the wall.

18. Comfort Suites At WestGate Mall

Spartanburg

$88

$98 total

includes taxes & fees

Nov 22 - Nov 23

A modern living room with a fireplace, two sofas, and a coffee table.

A hotel lobby with multiple seating areas, a reception desk, and a fireplace.

A reception area with two wooden reception desks, a blue accent wall, and a mounted television.

A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.

19. Best Western Spartanburg Northwest

Spartanburg

$88

$100 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor seating area with sofas, a fire pit, and string lights.

A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.

A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.

A modern interior with hanging chairs, tables, and a view of the parking lot.

20. Tru by Hilton Spartanburg

Spartanburg

$106

$117 total

includes taxes & fees

Nov 23 - Nov 24

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Go beyond your typical stay in Mayo

Pet friendly

Pool

Family friendly

Check out reviews of Mayo hotels guests love

Four Points by Sheraton Spartanburg

10/10 Excellent

"Very clean rooms and very friendly staff"

Hilton Garden Inn Spartanburg

10/10 Excellent

"J"

Best Western Plus Spartanburg

10/10 Excellent

"Clean room, excellent parking, and spectacular breakfast!!"

Best Western Spartanburg I-26

8/10 Good

"The bed was very comfortable! Slept like a rock. The room was very cleanThe bathroom sink was located outside the bathroom, which I always hate. The breakfast had a little pancake maker and a yogurt machine. There were eggs and bacon. The eggs were cold though. Lots of juice options, toast and bagels. Would recommend"

Days Inn by Wyndham Spartanburg Waccamaw

10/10 Excellent

"GREAT BED CLEAN PROPERTY"

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

8/10 Good

"The staff was very helpful providing information about Spartanberg as it was our first trip to the area. Breakfast at the hotel provided good choices. The room was clean."

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

10/10 Excellent

"Good hotel, clean room, great breakfast"

Spartanburg Marriott

10/10 Excellent

"Staff was friendly and helpful. Room was clean. We decided to dine in the restaurant on the property and were pleasantly surprised with how good the food was. Overall a great experience."

Extended Stay America Premier Suites - Greenville - Spartanburg - I-85

10/10 Excellent

"Nice stay. Decent morning cold breakfast, which I wasn’t expecting. They gave me pots and pans and cutlery. Nice front desk staff. Lots of parking. Very clean. Huge room."

Frequently asked questions

What accommodations do travelers recommend in Mayo?

Guests like Spartanburg Marriott, Holiday Inn Express Hotel & Suites Spartanburg-North by IHG and Best Western Spartanburg Northwest.

Can I book a refundable hotel in Mayo?

If you're looking for the flexibility to change your plans to Mayo, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Mayo be like during my visit?

July and August are typically the warmest months in Mayo when the average temp is 77°F. January and February are the coldest months when the average temperature is 46°F. December and April are the months with the most rain.

Why should I book my Mayo accommodation with Hotels.com?

There are lots of reasons to book your Mayo trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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