Hotels in Edisto

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Where to stay in Edisto?

A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.

A modern kitchen with a wooden table and bench, blue cabinets, and a yellow pendant light fixture.

A modern indoor swimming pool with clear glass walls, sunlit lounge areas, and a view of greenery outside.

A lobby with a reception desk, a staircase, and seating area with orange chairs.

1. Spark by Hilton Orangeburg

Orangeburg

$98

$108 total

includes taxes & fees

Oct 8 - Oct 9

A breakfast bar with pastries, fruits, and a vase with flowers.

A reception area with a dark-colored reception desk, a clock on the wall, and a doormat with "Travelodge" written on it.

A hotel room with two beds, a nightstand, and two wall-mounted lamps.

A hotel bathroom with a sink, mirror, towel rack, and a door leading to the bedroom.

2. Travelodge by Wyndham Orangeburg

Orangeburg

$62

$69 total

includes taxes & fees

Oct 5 - Oct 6

A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

A workspace with two desks, each with a computer monitor, keyboard, and chair.

A modern bar area with a stone fireplace, a flat-screen TV, and a coffee station.

A reception area with a wooden reception desk, a welcome mat, a vending machine, and a clock on the wall.

3. Fairfield Inn by Marriott Orangeburg

Orangeburg

$101

$112 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with a long counter, equipped with coffee makers, a kettle, and a microwave.

A hotel room with a beige armchair, a black ottoman, a standing lamp, and an air conditioning unit.

A living room with a brown leather sofa, a matching armchair, a coffee table, and a striped rug.

A multi-story hotel with a covered entrance, balconies, and a parking area.

4. Super 8 by Wyndham, Orangeburg

Orangeburg

$59

$65 total

includes taxes & fees

Oct 5 - Oct 6

A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.

A modern lobby with a wooden ceiling, a central seating area with a round table, and a bar with a variety of bottles.

A modern hotel room with a grey sofa, a flat-screen TV, a desk with a lamp, and abstract wall art.

A hotel room with two beds, a seating area, and a large abstract painting on the wall.

5. SpringHill Suites by Marriott Orangeburg

Orangeburg

$109

$121 total

includes taxes & fees

Oct 11 - Oct 12

A lobby with a reception desk, a sofa, a coffee station, and a flag.

A hotel room with a large bed, a desk, a chair, a nightstand, and a wall-mounted lamp.

A Holiday Inn Express & Suites building with a clear entrance, a covered waiting area, and a landscaped garden.

A modern hotel lobby with a green ceiling, a grey sofa, a patterned ottoman, a wooden bench, and a chair with a geometric throw.

6. Holiday Inn Express & Suites Orangeburg by IHG

Orangeburg

$105

$117 total

includes taxes & fees

Nov 1 - Nov 2

A self-service kiosk with a beverage cooler, microwave, and various food items.

A modern hotel lobby with a reception desk, blue and gray seating, a TV screen, and unique pendant lighting.

A breakfast counter with a sign reading 'TOP IT BREAKFAST,' a coffee machine, a yogurt dispenser, and various food items.

A modern interior with a dining area, seating arrangements, and a reception desk.

7. Tru by Hilton Orangeburg

Orangeburg

$118

$131 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a sofa, chairs, a coffee table, and a staircase with a green leaf-patterned wall.

A reception area with a staircase, reception desk, and seating area with blue sofas.

A hotel room with a bed, bedside tables, a nightstand, a lamp, a wall-mounted phone, a painting, a window with curtains, and an air conditioning unit.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a modern design.

8. Sleep Inn Orangeburg

Orangeburg

$83

$92 total

includes taxes & fees

Oct 25 - Oct 26

A two-story building with a grey facade, large windows, and a covered entrance area.

A Red Roof Inn with two red leather armchairs and a small wooden table in front of a stone-patterned wall.

A hotel reception area with a counter, coffee machines, and a refrigerator.

A hotel room with a bed, a nightstand, a chair, and a bathroom visible through an open door.

9. Red Roof Inn Orangeburg

Orangeburg

$57

$63 total

includes taxes & fees

Oct 19 - Oct 20

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A spacious living area with a ceiling fan, a sofa, a coffee table, and a TV.

A spacious lobby with a central round table and chairs, a bar area, and a staircase leading to an upper level.

A spacious dining area with a kitchen in the background, featuring a modern design with a ceiling fan, a clock, and a flat-screen TV mounted on the wall.

10. Quality Inn & Suites Orangeburg

Orangeburg

$60

$66 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with two beds, a desk, and a chair. There are wall-mounted lamps and a large window with curtains.

A reception area with a wooden reception desk, a wall-mounted clock, and a welcome mat.

A swimming pool with a 4ft depth marker, lounge chairs, and a covered seating area.

A Comfort Inn & Suites hotel with a brick facade, multiple windows, and a clear blue sky.

11. Comfort Inn & Suites Orangeburg

Orangeburg

$98

$108 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a bed, a desk, a chair, a sofa, and a table.

A gym with cardio equipment, dumbbells, and a TV on a shelf.

A Baymont Inn & Suites reception desk with a sign indicating Orangeburg, South Carolina.

A hotel with a swimming pool, outdoor seating, and a flagpole with an American flag.

12. Baymont by Wyndham Orangeburg North

Orangeburg

$55

$61 total

includes taxes & fees

Oct 12 - Oct 13

A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

A modern dining area with tables and chairs, large windows with sheer curtains, and pendant lighting.

A snack shop with a sign reading "Hampton Suite Shop" and a variety of snacks and drinks on display.

A gym with treadmills, a bench, and a ball.

13. Hampton Inn & Suites Orangeburg

Orangeburg

$130

$145 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a bed, a desk, a chair, and a hanging coat rack.

A modern kitchen with a granite countertop, a built-in microwave, a sink, and a mirror above the counter.

A room with two framed pictures on the wall, a table with a coffee machine, bowls, and a mug.

A spacious living area with a wooden floor, a ceiling fan, a flat-screen TV, and a large window with sheer curtains.

14. Suburban Studios Orangeburg

Orangeburg

$56

$62 total

includes taxes & fees

Oct 11 - Oct 12

A restaurant with round tables and chairs, a counter with a display case, and large windows.

A reception desk with a laptop, a patterned sofa, and a doormat with "SOUTHERN" visible.

A Southern Lodge building with a covered parking area, brick facade, and signage.

A kitchen with wooden cabinets, a stainless steel range hood, and a black refrigerator.

15. Southern Lodge 601

Orangeburg

$72

$80 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a sofa, a bed with a red blanket, two bedside lamps, a small table, and a TV.

A parking lot with multiple cars and a yellow truck.

A building with a covered entrance and a signboard.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

16. Orangeburg Inn & Suites

Orangeburg

$54

$61 total

includes taxes & fees

Oct 25 - Oct 26

View all properties

Go beyond your typical stay in Edisto

Check out reviews of Edisto hotels guests love

Hampton Inn & Suites Orangeburg

Orangeburg

10/10 Exceptional

Kevin

Holiday Inn Express & Suites Orangeburg by IHG

Orangeburg

10/10 Exceptional

Deborah

Fairfield Inn by Marriott Orangeburg

Orangeburg

10/10 Exceptional

Barry

Comfort Inn & Suites Orangeburg

Orangeburg

10/10 Exceptional

Ken

Spark by Hilton Orangeburg

Orangeburg

10/10 Exceptional

Garrick

Super 8 by Wyndham, Orangeburg

Orangeburg

10/10 Exceptional

Suburban Studios Orangeburg

Orangeburg

10/10 Exceptional

Rhonda

Frequently Asked Questions

What accommodations do travelers like in Edisto?

Guests like Crown Inn By Oyo Orangeburg Hwy 301, Tru by Hilton Orangeburg and SpringHill Suites by Marriott Orangeburg.

Can I book refundable accommodations in Edisto?

If you need the flexibility to change your plans to Edisto, most hotels provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where should I stay in Edisto if I'm looking for a budget-friendly accommodation?

An inexpensive option worth considering is Crown Inn By Oyo Orangeburg Hwy 301.

What will the weather in Edisto be like during my trip?

July and August are typically the warmest months in Edisto when the average temp is 79°F. January and February are the coldest months when the average temperature is 51°F. August and July are the months with the most rain.

Why should I book my Edisto hotel through Hotels.com?

There are lots of reasons to book your Edisto trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.