Hotels in East Cape Girardeau

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Check prices for these dates

Tonight
Oct 30 - Oct 31
Tomorrow
Oct 31 - Nov 1
This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Where to stay in East Cape Girardeau?

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,004 reviews)
Located minutes from Shawnee National Forest, this hotel offers a refreshing indoor pool and hot tub for unwinding after adventures. Enjoy complimentary breakfast, WiFi, and parking while being close to Cape Splash Family Aquatic Center.
The price is $100
$113 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
Discover Cape Girardeau from this central hotel with easy access to restaurants and shopping. Enjoy the indoor pool and fitness center, then wake up to a free breakfast. Helpful staff ensure a smooth stay with convenient free WiFi and parking.
The price is $95
$108 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

3. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
Peaceful retreat in Cape Girardeau with shopping and restaurants within walking distance. Start your day with free breakfast before enjoying the indoor pool, then unwind in the hot tub. Near Cape Splash Family Aquatic Center with free WiFi and parking.
The price is $90
$102 total
includes taxes & fees
Nov 5 - Nov 6
Drury Inn & Suites Cape Girardeau
A spacious lobby with marble flooring, elegant seating, and a grand staircase.

4. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (556 reviews)
Experience Mississippi River views and explore Shawnee National Forest from this downtown Marriott. The Bistro serves American cuisine while in-room refrigerators and washers/dryers enhance comfort. Enjoy the 24-hour fitness center after visiting nearby Riverfront Park and Isle Casino.
The price is $116
$132 total
includes taxes & fees
Nov 15 - Nov 16
Courtyard by Marriott Cape Girardeau Downtown
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

5. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (856 reviews)
Wake up to a free breakfast at this Cape Girardeau hotel, just minutes from Shawnee National Forest and the Mississippi River. Swim in the indoor pool, work out in the fitness center, or relax on the terrace after exploring nearby aquatic attractions.
The price is $98
$110 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn Cape Girardeau I 55 East
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

6. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (239 reviews)
Discover Cape Girardeau from this hotel with free WiFi, parking, and continental breakfast. Take a refreshing dip in the indoor pool after exploring nearby attractions like Fort D Historic Site and Cape Splash Family Aquatic Center.
The price is $101
$114 total
includes taxes & fees
Nov 5 - Nov 6
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

7. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (696 reviews)
Overlooking the Mississippi River, this hotel puts you near Isle Casino Cape Girardeau and Riverfront Park. Enjoy 2 restaurants including Beacon 53, plus free WiFi and complimentary parking during your business-friendly stay.
The price is $114
$129 total
includes taxes & fees
Nov 1 - Nov 2
The Riverview
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

8. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1,001 reviews)
This tranquil hotel provides easy access to Cape Splash Family Aquatic Center and Conservation Nature Center. Enjoy complimentary breakfast, WiFi, and parking, with helpful staff ensuring a relaxing atmosphere near local restaurants and shopping.
The price is $72
$81 total
includes taxes & fees
Nov 8 - Nov 9
Pear Tree Inn Cape Girardeau West
A modern retail area with a display of local items and snacks.

9. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (198 reviews)
This Cape Girardeau hotel offers convenient access to Shawnee National Forest and local nature attractions. Start each morning with free breakfast before exploring nearby conservation areas, then return for a swim in the indoor pool or a workout at the fitness center.
The price is $89
$102 total
includes taxes & fees
Nov 5 - Nov 6
Tru By Hilton Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

10. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (1,000 reviews)
The price is $71
$86 total
includes taxes & fees
Nov 22 - Nov 23
Candlewood Suites Cape Girardeau by IHG
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.0 out of 10, Good, (815 reviews)
Escape to this welcoming hotel featuring an outdoor pool and free daily English breakfast. Just minutes from Mississippi River and popular attractions, with free WiFi and parking. Guests rave about the helpful staff ready to make your stay enjoyable.
The price is $59
$67 total
includes taxes & fees
Nov 8 - Nov 9
Quality Inn Cape Girardeau North
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

12. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (888 reviews)
The price is $80
$86 total
includes taxes & fees
Nov 2 - Nov 3
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

13. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,000 reviews)
This peaceful Jackson hotel features a relaxing hot tub and indoor swimming pool. Free breakfast, WiFi, and parking add value, while the helpful staff ensures a comfortable stay. Litz Park and Lazy L Safari Park are nearby attractions to explore.
The price is $80
$85 total
includes taxes & fees
Nov 8 - Nov 9
Drury Inn & Suites Jackson MO
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

14. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, Good, (243 reviews)
Wake up to adventure at this Cape Girardeau motel near the Family Aquatic Center and Show Me Center. Enjoy hassle-free travel with free WiFi, complimentary parking, and 24-hour front desk service for your Missouri getaway.
The price is $70
$82 total
includes taxes & fees
Oct 31 - Nov 1
Town House Inn Cape Giradreau
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

15. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.0 out of 10, Very good, (785 reviews)
Begin your day with a complimentary breakfast at this Jackson hotel near Mississippi River and Shawnee National Forest. The indoor pool offers year-round swimming while free WiFi and parking add value. Cape Girardeau Conservation Nature Center awaits nearby.
The price is $76
$82 total
includes taxes & fees
Nov 22 - Nov 23
Comfort Suites Jackson-Cape Girardeau
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

16. Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (450 reviews)
Feel welcomed at this cozy motel with friendly service just minutes from Shawnee National Forest. Enjoy convenient perks including complimentary WiFi and parking, plus easy access to Litz Park and Lazy L Safari Park for outdoor adventures.
The price is $79
$86 total
includes taxes & fees
Nov 1 - Nov 2
Town House Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in East Cape Girardeau

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Check out reviews of East Cape Girardeau hotels guests love

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau

10/10 Exceptional

I would like to see hand lotion in the room or bathroom. It always used to be in the rooms of most every hotel, and now for some reason we can't have it. The breakfast was great, the hotel was very nice and the room was great. There was a hot tub and pool.
United States
Marilyn
Reviewed October 28, 2026
Drury Plaza Hotel Cape Girardeau Conference Center

Frequently Asked Questions

What hotels do travelers recommend in East Cape Girardeau?

Guests like Drury Plaza Hotel Cape Girardeau Conference Center, Pear Tree Inn Cape Girardeau West and The Riverview.

Can I book refundable accommodations in East Cape Girardeau?

If you need the flexibility to change your plans to East Cape Girardeau, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in East Cape Girardeau be like during my trip?

July and August are typically the warmest months in East Cape Girardeau when the average temp is 76°F. January and February are the coldest months when the average temperature is 40°F. April and March are the months with the most rain.

Why should I book my East Cape Girardeau hotel with Hotels.com?

There are lots of reasons to book your East Cape Girardeau trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.