Hotels in Panama

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Check prices for these dates

This weekend
Jun 19 - Jun 21
Next weekend
Jun 26 - Jun 28

Where to stay in Panama?

Lobby sitting area

Super 8 by Wyndham Staunton

Super 8 by Wyndham Staunton
2.0 star property
Staunton
8.6 out of 10, Excellent, (796 reviews)
Wake up to complimentary continental breakfast at this quiet Super 8 hotel. Located near Timber Lakes Golf Course and The Winery at Shale Lake, it offers free Wi-Fi and parking. Helpful staff ensure a pleasant stay just 48 minutes from St. Louis Lambert Airport.
The price is $79
$88 total
includes taxes & fees
Jun 21 - Jun 22
Super 8 by Wyndham Staunton
Lobby

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
2.5 star property
Greenville
8.4 out of 10, Very Good, (448 reviews)
This business-friendly hotel offers a refreshing indoor pool and complimentary WiFi, buffet breakfast, and parking. Located near Patriot's Park and Greenville Country Club, guests consistently praise the helpful staff who enhance every stay.
The price is $112
$124 total
includes taxes & fees
Jun 28 - Jun 29
Comfort Inn & Suites Greenville I-70
Indoor pool, open 7:00 AM to 10:00 PM, sun loungers

Baymont by Wyndham Litchfield

Baymont by Wyndham Litchfield
2.5 star property
Litchfield
8.2 out of 10, Very Good, (1,000 reviews)
Modern comfort awaits at this Litchfield hotel near Route 66 Welcome Center and Madison Park. Unwind in the hot tub after a workout in the 24-hour fitness center. Enjoy complimentary breakfast, WiFi, and parking while the attentive staff ensures a pleasant stay.
The price is $85
$93 total
includes taxes & fees
Jun 21 - Jun 22
Baymont by Wyndham Litchfield
Room, 1 King Bed, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets

Budget Inn by Hotel O Greensville I 70

Budget Inn by Hotel O Greensville I 70
2.0 star property
Greenville
6.8 out of 10, (183 reviews)
Enjoy convenient perks at this affordable Greenville motel, including complimentary WiFi and self parking. The 24-hour front desk ensures assistance anytime, while nearby attractions like Greenville Country Club and Patriot's Park offer local entertainment.
The price is $58
$70 total
includes taxes & fees
Jun 21 - Jun 22
Budget Inn by Hotel O Greensville I 70
Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn Litchfield Route 66

Quality Inn Litchfield Route 66
2.5 star property
Litchfield
8.6 out of 10, Excellent, (645 reviews)
Just minutes from Litchfield Museum and Route 66 Welcome Center, this freshly renovated hotel features an indoor pool and fitness center. Enjoy free breakfast, WiFi, and parking while the helpful staff ensures a comfortable visit near Madison Park.
The price is $89
$98 total
includes taxes & fees
Jun 21 - Jun 22
Quality Inn Litchfield Route 66
Desk, laptop workspace, iron/ironing board, bed sheets

SureStay Hotel by Best Western Greenville

SureStay Hotel by Best Western Greenville
2.5 star property
Greenville
7.4 out of 10, Good, (586 reviews)
Escape to a peaceful haven where the indoor pool invites relaxation after exploring nearby Greenville Country Club. Free continental breakfast starts your day right, while helpful staff and clean rooms earn consistent praise from fellow travelers.
The price is $61
$68 total
includes taxes & fees
Jun 28 - Jun 29
SureStay Hotel by Best Western Greenville
Exterior

Holiday Inn Express & Suites Litchfield West by IHG

Holiday Inn Express & Suites Litchfield West by IHG
2.5 star property
Litchfield
9.6 out of 10, Exceptional, (634 reviews)
Just 62 minutes from St. Louis Lambert Airport, this Litchfield hotel offers an energizing morning swim and convenient fitness center. Guests love the helpful team, free breakfast, and easy parking. Visit nearby Route 66 Welcome Center while enjoying in-room refrigerators.
The price is $118
$130 total
includes taxes & fees
Jul 18 - Jul 19
Holiday Inn Express & Suites Litchfield West by IHG
Restaurant

Hampton Inn by Hilton Litchfield

Hampton Inn by Hilton Litchfield
2.5 star property
Litchfield
9.0 out of 10, Wonderful, (664 reviews)
Close to the Litchfield Museum and Route 66 Welcome Center, this hotel offers a welcoming indoor pool, hot tub, and fitness center. Enjoy free WiFi, parking, and breakfast before exploring nearby Madison Park or relaxing on the outdoor terrace.
The price is $99
$109 total
includes taxes & fees
Jul 5 - Jul 6
Hampton Inn by Hilton Litchfield
Classic Room, 1 King Bed | Desk, free WiFi, bed sheets

Powhatan Motel

Powhatan Motel
2.5 star property
Pocahontas
8.6 out of 10, Excellent, (211 reviews)
Escape to this charming Pocahontas retreat where friendly staff welcome you to relax. Grab a drink at the bar or a bite at the café. With free breakfast, WiFi and parking, plus nearby Copper Dock Winery, convenience meets comfort.
The price is $97
$103 total
includes taxes & fees
Jun 19 - Jun 20
Powhatan Motel
Front of property

Lighthouse Lodge

Lighthouse Lodge
2.0 star property
Pocahontas
8.8 out of 10, Excellent, (27 reviews)
Embrace tranquil moments at this Pocahontas lodge featuring convenient amenities including complimentary WiFi and parking. After exploring nearby Copper Dock Winery, return to comfortable accommodations with practical laundry facilities.
The price is $82
$92 total
includes taxes & fees
Jun 30 - Jul 1
Lighthouse Lodge
Desk, iron/ironing board, free cribs/infant beds, rollaway beds

Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
2.0 star property
Greenville
8.0 out of 10, Very Good, (803 reviews)
Start your day with complimentary continental breakfast at this welcoming Greenville motel. Free WiFi and parking enhance your stay, while the helpful staff earns praise from fellow travelers. Greenville Country Club and Patriot's Park await just moments away.
The price is $65
$72 total
includes taxes & fees
Jun 29 - Jun 30
Super 8 by Wyndham Greenville
Property amenity

Motel 6 Litchfield, IL

Motel 6 Litchfield, IL
2.0 star property
Litchfield
7.2 out of 10, Good, (171 reviews)
This roadside motel sits near the Litchfield Museum and Route 66 Welcome Center, offering 24-hour front desk service. Madison Park is nearby, with free WiFi and self parking. Springfield Capital Airport is just a 56-minute drive away.
The price is $61
$67 total
includes taxes & fees
Jun 19 - Jun 20
Motel 6 Litchfield, IL
Combined shower/tub, free toiletries, towels

Countryside Inn

Countryside Inn
2.0 star property
Hillsboro
5.8 out of 10, (40 reviews)
This charming Hillsboro motel welcomes travelers with complimentary WiFi and self-parking. Enjoy 24-hour front desk service for assistance anytime during your stay, making it an ideal base for exploring the surrounding countryside.
The price is $79
$87 total
includes taxes & fees
Jun 19 - Jun 20
Countryside Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out reviews of Panama hotels guests love

Hampton Inn by Hilton Litchfield

Hampton Inn by Hilton Litchfield

10/10 Excellent
"Nice place. Too high buy nice."
Jerrod 1-night trip
Posted 11 hours ago
Hampton Inn by Hilton Litchfield

Frequently asked questions

What accommodations do travelers like in Panama?
Guests like Historic Red Rooster Inn and Countryside Inn.
Can I book a refundable hotel in Panama?
If you need the flexibility to change your travel plans to Panama, most properties provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Panama be like during my vacation?
July and August are typically the warmest months in Panama when the average temp is 73°F. January and February are the coldest months when the average temperature is 36°F. April and May are the months with the most rain.
Why should I book my Panama hotel through Hotels.com?
There are lots of reasons to book your Panama trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.