Hotels in Saint Charles

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A spacious lobby with high ceilings, large windows, and a chandelier.

A spacious lobby with high ceilings, large windows, and a central chandelier. There are multiple seating areas with tables and chairs.

A double door entrance to a hotel with a sign above reading "PROUDFOOT & BIRD".

A spacious lobby with a central round table, green seating, and large arched windows.

1. Hotel Fort Des Moines, Curio Collection by Hilton

Downtown Des Moines

$126

$141 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.

An indoor swimming pool with clear windows, white chairs, and a blue and white color scheme.

A brick building with a covered entrance and a car parked in front.

2. Days Inn & Suites by Wyndham Des Moines Airport

Greater South Side

$70

$79 total

includes taxes & fees

Sep 20 - Sep 21

A modern hotel room with a large bed, a built-in desk, a vanity with a bathtub, and a large window with curtains.

A restaurant with multiple tables and chairs, a kitchen area, and a stone accent wall.

A hallway with vending machines and a clean, tiled floor.

A multi-story hotel with a modern design, featuring a stone facade and multiple windows.

3. Sonesta Essential Des Moines

Lovington

$61

$71 total

includes taxes & fees

Sep 17 - Sep 18

An indoor pool with slides and a ship-themed play area.

A bar area with a central counter, multiple bar stools, and a decorative figure on top.

A lobby with a reception desk, a curved seating area, and a decorative palm tree centerpiece.

A spacious restaurant with wooden tables and chairs, a stone wall, and a large window overlooking the dining area.

4. Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Urbandale

$71

$80 total

includes taxes & fees

Sep 16 - Sep 17

A spacious, modern interior with a long wooden table and bar stools, a seating area with sofas, and a kitchen area with a countertop and shelving.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables.

A modern conference room with a large wooden table, comfortable seating, and a fireplace.

5. GrandStay Hotel & Suites

Johnston

$101

$113 total

includes taxes & fees

Sep 13 - Sep 14

A building with a sign reading "WILDWOOD LODGE."

An indoor swimming pool with a stone-tiled floor, red-framed windows, and a sign reading "LAKE WILDWOOD".

A spacious lobby with a reception desk, seating area, and a view of the outdoors.

A spacious lobby with a central seating area, large windows, and a distinctive antler decoration.

6. Wildwood Lodge

Clive

$93

$104 total

includes taxes & fees

Sep 13 - Sep 14

An indoor swimming pool with a 30 ft depth sign, a reception area, and a 'No Lifeguard' warning sign.

A lobby with a checkered armchair, a yellow sofa, a glass-top coffee table, and a cabinet with glass doors.

A lobby with striped orange chairs, a green ottoman, and a fireplace.

A hotel room with two beds, a desk, a television, and a dresser.

7. Drury Inn & Suites West Des Moines

West Des Moines

$100

$112 total

includes taxes & fees

Sep 20 - Sep 21

An outdoor dining area with a table set for two, featuring a cocktail and candles.

A row of tables with metallic pitchers and crystal glassware, set against a purple-lit background.

A multi-level hotel atrium with balconies, indoor plants, and artwork on the walls.

A multi-level hotel lobby with a central pool, dining area, and a bar.

8. Embassy Suites Hotel Des Moines Downtown

Downtown Des Moines

$130

$146 total

includes taxes & fees

Sep 20 - Sep 21

An outdoor seating area with yellow chairs and a colorful sofa, a fire pit, and a wooden ceiling with hanging lights.

A hotel with a modern exterior, a covered outdoor seating area, and a traditional building in the background.

A modern lounge area with a sofa, ottomans, and tables, featuring a mix of red and yellow chairs.

A hotel room with a large bed, a desk with a computer, a TV, and a kitchenette.

9. Home2 Suites by Hilton Des Moines at Drake University

Drake

$107

$120 total

includes taxes & fees

Sep 20 - Sep 21

A luxurious living room with a stone fireplace, a large mirror, and two blue armchairs.

A hotel lobby with a polished marble floor, a grand chandelier, and traditional decor including lion statues.

A spacious hotel lobby with high ceilings, ornate chandeliers, and a bar area.

A hotel facade with a brick exterior, large windows, and a prominent entrance sign.

10. Des Lux Hotel

Downtown Des Moines

$189

$212 total

includes taxes & fees

Sep 16 - Sep 17

An indoor swimming pool with tiled flooring, a wooden ceiling, and a seating area with chairs and umbrellas.

A spacious living area with a staircase, a fireplace, a wooden desk, and a dining area.

A reception area with a wooden counter, overhead pendant lights, framed pictures on the wall, and a refrigerator stocked with beverages.

A covered patio with a wooden table and chairs, a cushioned bench, and a hanging plant.

11. Country Inn & Suites by Radisson, Des Moines West, IA

Clive

$82

$92 total

includes taxes & fees

Sep 20 - Sep 21

An indoor swimming pool with a waterfall feature, surrounded by Adirondack chairs and a wooden deck.

A wooden interior with a reception desk, a mounted moose head, and a staircase.

A hotel room with a large bed, a fireplace, a TV, and a jacuzzi.

A cozy room with a stone fireplace, a flat-screen TV mounted above it, a sofa, a bed, and a window with blinds.

12. Stoney Creek Hotel Des Moines - Johnston

Johnston

$109

$122 total

includes taxes & fees

Sep 13 - Sep 14

A spacious lobby with a high ceiling, a central seating area with a blue sofa and chairs, a dining area, and a staircase leading to an upper level.

A spacious lobby with a curved blue sofa, a round coffee table, and a seating area with chairs. There is a staircase with a railing leading to an upper level.

A vending machine area with various snacks and drinks.

A hotel dining area with multiple tables and chairs, a kitchen area with a microwave and refrigerator, and a colorful carpet.

13. Fairfield Inn and Suites by Marriott Des Moines West

West Des Moines

$98

$110 total

includes taxes & fees

Oct 12 - Oct 13

A spacious indoor area with multiple levels, featuring a central open space with tables and chairs, surrounded by balconies and a large, colorful ceiling structure.

A gym with treadmills, elliptical machines, and free weights.

A multi-level indoor swimming pool with a clear water surface, surrounded by colorful lounge chairs and a stone wall.

A spacious lobby with large windows, a potted plant, and a seating area.

14. Holiday Inn Des Moines-Airport/Conf Center by IHG

Greater South Side

$114

$128 total

includes taxes & fees

Oct 11 - Oct 12

A living room with a sofa, a patterned armchair, a coffee table, and a dining area with chairs and a table.

An indoor swimming pool with blue lounge chairs, a red brick border, and a ceiling with recessed lighting.

A breakfast area with a chalkboard sign, coffee machines, and a fruit bowl.

An outdoor patio area with picnic tables and benches, large windows, and a building with a brick facade in the background.

15. AmericInn by Wyndham Johnston Des Moines

Johnston

$60

$67 total

includes taxes & fees

Sep 17 - Sep 18

An outdoor dining area with tables and chairs, a large umbrella, and a TV screen.

A modern restaurant with a large, abstract wall art piece, multiple seating areas, and a staircase leading to an upper level.

A spacious lobby with a central reception desk, seating areas, and artwork on the walls.

A modern hotel with a prominent 'Hilton' sign, large windows, and a covered outdoor area with seating.

16. Hilton Des Moines Downtown

Downtown Des Moines

$136

$157 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor patio with modern seating and a built-in fireplace.

A La Quinta hotel entrance with a modern design, numbered 1390, and a landscaped entrance area.

A modern restaurant with a long counter, multiple seating areas, and a kitchen visible in the background.

A hotel bathroom with a large mirror, a sink, and a chair.

17. La Quinta Inn & Suites by Wyndham Des Moines West Clive

Clive

$83

$93 total

includes taxes & fees

Sep 20 - Sep 21

A bar area with multiple screens displaying sports and news, a cash register, and bar stools.

A coffee shop interior with a menu board, a bakery display case, and a counter with a cash register.

A hotel with a pool area, outdoor seating, and a building with multiple floors and windows.

A lobby with a stone wall, a fireplace, a TV, red sofas, and two lamps.

18. Lakeside Hotel Casino, a Travelodge by Wyndham

Osceola

$72

$95 total

includes taxes & fees

Sep 14 - Sep 15

A sunroom with a glass ceiling, wicker furniture, and potted plants.

A spacious lobby with a high ceiling, a seating area with sofas and ottomans, a reception desk, and a staircase to an upper level.

A hotel room with a bed, a blue armchair, a desk, and a nightstand.

A clean, well-lit breakfast area with a self-service station, a coffee machine, and a variety of food items.

19. Baymont by Wyndham Des Moines Airport

Southwestern Hills

$94

$106 total

includes taxes & fees

Oct 11 - Oct 12

A spacious hotel lobby with a blue sofa, a grey armchair, and a flat-screen TV mounted on a textured wall.

A hotel lobby with a blue sofa, a beige armchair, a flat-screen TV mounted on a textured wall, a fireplace, and a dining area in the background.

An indoor swimming pool with a blue and white color scheme, a lifeguard station, and seating areas with chairs and tables.

A Comfort Inn hotel with a modern facade, multiple floors, and a parking lot with cars.

20. Comfort Inn & Suites Event Center

Downtown Des Moines

$94

$105 total

includes taxes & fees

Sep 20 - Sep 21

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Go beyond your typical stay in Saint Charles

Pet friendly

Hot tub

Pool

Family friendly

Top landmarks in Saint Charles

Imes Bridge

7.8/10 (17 reviews)

If you're planning a bit of sightseeing during your trip, head to Imes Bridge— just one of the landmarks located 0.5 mi (0.9 km) from central Saint Charles.

See properties

Learn more about Saint Charles

The region around Saint Charles is home to attractions such as Imes Bridge and John Wayne Birthplace Museum.

See all hotels in Saint Charles

A covered bridge with a sign reading "GUTLER-DONAHUE BRIDGE Built 1870" in a forested area.

Check out reviews of Saint Charles hotels guests love

Drury Inn & Suites West Des Moines

10/10 Excellent

"We enjoyed it very much. Great value and great experience. Thank you to everyones. Word of mouth advertising is the best."

SpringHill Suites Des Moines West

8/10 Good

"Clean and comfortable bed"

Holiday Inn Des Moines-Airport/Conf Center by IHG

10/10 Excellent

".."

Country Inn & Suites by Radisson, Des Moines West, IA

8/10 Good

"Breakfast was great"

La Quinta Inn & Suites by Wyndham Des Moines West Clive

8/10 Good

"Clean Room and Good Breakfast. Have coffee and Hot Chocolate available at all times."

Des Lux Hotel

10/10 Excellent

"This is a really nice Hotel. Very tall ceilings, unique art work, and friendly staff."

Hilton Des Moines Downtown

8/10 Good

"Stayed in the sky suite very spacious. The only downfall the shower door slides to left and the fixed glass should have been right to prevent water from getting on the floor and you have this stainless drain cover if you step on it causes it to be ajar and a slipping hazard just a poor layout for this reason I wouldn’t stay at that property again"

Frequently asked questions

Can I book a refundable hotel in Saint Charles?

If you're looking for the flexibility to change your plans to Saint Charles, most hotels provide refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Saint Charles be like during my trip?

The warmest months in Saint Charles are usually July and August with an average temp of 72°F. January and February are the chilliest months when the average temp is 29°F. The rainiest months are May and June.

Why should I book my Saint Charles hotel through Hotels.com?

There are plenty of reasons to book your Saint Charles travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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