Top 10 Hotels in Buffalo, SC in 2026 (from $64)

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Where to stay in Buffalo?

A modern hotel lobby with a coffee station, seating area, and a large screen.

A breakfast bar with a microwave, toaster, and clear plastic containers. There are framed pictures on the wall and a refrigerator.

A hotel entrance with a clear view of the greenery outside, a doormat with the hotel name, and emergency instructions on the glass doors.

A reception area with a brick counter, a framed certificate on the wall, and a sign indicating hotel ownership.

1. Quality Inn Union US Hwy 176

Union

$84

$93 total

includes taxes & fees

Nov 6 - Nov 7

A hotel room with a bed, a sofa, a nightstand, and a small table.

A reception area with a blue wall, a wooden counter, a glass door leading outside, and a potted plant.

A row of residential buildings with a blue door, a white window, and a vent on the wall.

A rectangular pool with a blue border, surrounded by a black fence. There are lounge chairs and a small table with chairs along the poolside.

2. Rodeway Inn Union

Union

$65

$70 total

includes taxes & fees

Nov 5 - Nov 6

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A hotel room with a wooden table, a black office chair, a black refrigerator, and a large mirror on the wall.

A motel with a single-story structure, a covered parking area, and a well-maintained lawn.

A reception area with a counter, seating, a clock, and a sign for 'The Night'.

3. The Night Inn

Union

$65

$76 total

includes taxes & fees

Oct 17 - Oct 18

A modern lobby with a reception desk, seating area, and a television screen.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.

4. Best Western Spartanburg I-26

Spartanburg

$93

$103 total

includes taxes & fees

Nov 1 - Nov 2

A hotel with a central entrance, multiple floors, and a flag display.

A hotel room with a bed, a sofa, a coffee table, two lamps, a framed picture, and a mirror.

A breakfast buffet with various food items, coffee machines, and a toaster.

A hotel room with a desk, chair, bed, and a bathroom with a sink and mirror.

5. Comfort Suites Clinton near Presbyterian College

Clinton

$90

$104 total

includes taxes & fees

Nov 5 - Nov 6

A conference room with round tables, orange chairs, and a patterned carpet.

A modern living room with a flat-screen TV, a wooden desk, a trash bin, and a red chair.

A hotel room with a bed, a desk, a chair, a TV, a window with curtains, an air conditioner, and a bedside lamp.

6. Hampton Inn & Suites Clinton - I-26

Clinton

$132

$148 total

includes taxes & fees

Nov 11 - Nov 12

A modern living room with a sofa, armchairs, a patterned rug, and a Buddha statue.

A conference room with tables and chairs, a television, and a whiteboard.

A hotel room with two beds, a sofa, a TV, and a window with curtains.

A swimming pool with a lifeguard chair, a shallow water sign, and a no diving allowed sign.

7. Days Inn by Wyndham Clinton / Laurens I-26

Clinton

$68

$76 total

includes taxes & fees

Oct 18 - Oct 19

A modern hotel lobby with a long reception desk, bar area with stools, seating with patterned cushions, and a large window offering a view of greenery.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

A Holiday Inn Express hotel with a covered entrance, brick facade, and large windows.

A hotel room with a kitchenette, two beds, a red sofa, and a dining area.

8. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Spartanburg

$103

$114 total

includes taxes & fees

Nov 15 - Nov 16

A modern living room with a stone accent wall, a flat-screen TV, and a blue abstract rug.

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A modern dining area with wooden flooring, round tables, and chairs. There are wall-mounted artworks and a sign that reads "LESS MONDAY MORE SUMMER".

A modern hotel with a prominent Fairfield sign, multiple floors, and a well-lit entrance.

9. Fairfield by Marriott Inn & Suites Spartanburg Downtown

Spartanburg

$149

$165 total

includes taxes & fees

Oct 25 - Oct 26

A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.

A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.

A modern kitchen with marble countertops, wooden shelves, and a wine station.

A lobby with a stone fireplace, sofas, a TV mounted on the wall, and a bar area in the background.

10. Spartanburg Marriott

Spartanburg

$118

$131 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with two beds, a desk, a bathroom, and a TV.

A modern hotel lobby with a seating area, a dining space, and a reception desk.

A home gym with a treadmill, stationary bike, bench, and dumbbells.

A modern hotel with a covered entrance, multiple balconies, and a parking area.

11. Quality Inn Clinton - Laurens I-26

Clinton

$75

$87 total

includes taxes & fees

Nov 1 - Nov 2

A rooftop bar with seating, a bar area, and a view of the cityscape at dusk.

A modern living room with a dark-colored sofa, armchairs, a coffee table, and a bookshelf filled with decorative items.

A modern restaurant with a bar area, high ceilings, and a view of the cityscape.

A spacious living area with a modern sofa, armchairs, a coffee table, and a dining area with chairs and a table.

12. AC Hotel by Marriott Spartanburg

Spartanburg

$159

$176 total

includes taxes & fees

Oct 18 - Oct 19

An outdoor seating area with sofas, a fire pit, and string lights.

A modern interior with hanging chairs, tables, and a view of the parking lot.

A self-service kiosk with a variety of snacks and beverages, a microwave, and a refrigerated display.

A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.

13. Tru by Hilton Spartanburg

Spartanburg

$106

$117 total

includes taxes & fees

Nov 1 - Nov 2

A bar area with a long counter, multiple stools, and shelves stocked with bottles.

A restaurant with a central island seating area, multiple tables, and a large mural on the wall.

A spacious lobby with a bar area, seating, and large windows.

An outdoor seating area with string lights, tables, and chairs at the Hilton Garden Inn.

14. Hilton Garden Inn Spartanburg

Spartanburg

$118

$131 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.

A modern lobby with blue sofas, a reception desk, and a glass coffee table.

A hotel room with a desk, office chair, sofa, and a large wall art piece.

A hotel room with a bed, a gray sofa, two ottomans, a window with a view, and abstract artwork on the wall.

15. Comfort Suites At WestGate Mall

Spartanburg

$91

$101 total

includes taxes & fees

Nov 8 - Nov 9

A dining area with tables and chairs, a television mounted on the wall, and a kitchen area with appliances.

A hotel room with a bed, a desk with a computer, a chair, a lamp, and a view of the outdoors through a window.

A hotel room with patterned green sofas, a wooden table, and a green wall.

A Rodeway Inn with a two-story building, a parking lot, and a few cars parked in front.

16. Rodeway Inn Laurens

Laurens

$68

$76 total

includes taxes & fees

Nov 15 - Nov 16

A modern kitchen with a central island, bar stools, and pendant lighting.

A large indoor swimming pool with clear water, surrounded by lounge chairs and tables, and equipped with safety signage.

A modern hotel lobby with a large TV, comfortable seating, and a view of the outdoors.

A hotel lobby with a reception desk, seating area, and large windows.

17. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Spartanburg

$110

$122 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a blue sofa, a wooden coffee table, a desk with a chair, and a framed abstract painting on the wall.

A large indoor swimming pool with a diving board, multiple doors, and seating areas.

A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a desk with a chair, and a large window.

A food service counter with a sign that reads "EXPRESS START".

18. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Spartanburg

$107

$119 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a bed, a desk with a computer, a television, and a microwave.

A bathroom with a bathtub, shower curtain, and marble wall tiles.

A room with two beds, each with a wooden headboard and a floral bedspread. There is a small wooden table beside the beds.

A single-story motel with a flat roof, large windows, and a small porch area.

19. SUN AND SAND MOTEL

Spartanburg

$70

$77 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor patio with a fire pit, wicker furniture, and a stone wall.

A multi-story hotel with a modern design, featuring a mix of brick and stucco exteriors, and a well-lit entrance area with outdoor seating.

A modern lounge area with a sofa, chairs, and tables, featuring a glass partition, pendant lights, and artwork on the walls.

A spacious living area with a fireplace, comfortable seating, and a large TV.

20. Residence Inn by Marriott Spartanburg Westgate

Spartanburg

$142

$157 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Go beyond your typical stay in Buffalo

Check out reviews of Buffalo hotels guests love

Rodeway Inn Union

Union

10/10 Exceptional

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Spartanburg

10/10 Exceptional

PATRICIA

A conference room with a long table, blue and orange chairs, and a reception desk in the background.

A gym with treadmills, elliptical machines, and weight machines.

A conference room with two desks, two chairs, and a small table.

A Hampton Inn hotel with a clear entrance, well-maintained lawn, and a flagpole.

Hampton Inn Spartanburg-North I-85

Spartanburg

10/10 Exceptional

jenny

Frequently Asked Questions

What hotels do travelers like in Buffalo?

Guests like Rodeway Inn Union.

Can I book a refundable hotel in Buffalo?

If you want the flexibility to change your travel plans to Buffalo, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Buffalo be like during my trip?

The warmest months in Buffalo are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 47°F. The rainiest months are December and August.

Why should I book my Buffalo hotel with Hotels.com?

There are plenty of reasons to book your Buffalo travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.