Hotels in Santee

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Check prices for these dates

Tonight
Feb 2 - Feb 3
Tomorrow
Feb 3 - Feb 4
This weekend
Feb 6 - Feb 8
Next weekend
Feb 13 - Feb 15

Where to stay in Santee?

Family Quadruple Room | Living area | 32-inch LCD TV with digital channels, TV
Lewis and Clark Resort
Lewis and Clark Resort
2.5 star property
Yankton
8.8 out of 10, Excellent, (288 reviews)
  • cleanliness
    Perfect choice for boaters with direct marina and lake access in scenic Yankton.
The price is $89
$94 total
includes taxes & fees
Feb 3 - Feb 4
Lewis and Clark Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out reviews of Santee hotels guests love

Lewis and Clark Resort

Lewis and Clark Resort

10/10 Excellent
"Clean, full kitchen "
Jacquelynn 1-night trip
Posted 2 months ago
Lewis and Clark Resort

Frequently asked questions

Can I book refundable hotels in Santee?
If you want the flexibility to change your plans to Santee, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Santee be like during my visit?
The warmest months in Santee are usually July and August with an average temp of 72°F. January and February are the chilliest months when the average temp is 26°F. The rainiest months are June and May.
Why should I book my Santee accommodation with Hotels.com?
There are lots of reasons to book your Santee trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.