Hotels in Old Appleton

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Where to stay in Old Appleton?

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A hotel room with two beds, a brick wall, and a wooden headboard.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

1. Drury Inn & Suites Jackson MO

Jackson

$80

$85 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

2. Super 8 by Wyndham Perryville

Perryville

$68

$78 total

includes taxes & fees

Nov 8 - Nov 9

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A Holiday Inn Express & Suites building with a covered entrance and multiple windows.

A hotel breakfast area with a counter, food dispensers, and a refrigerator.

A kitchen counter with a coffee machine, a kettle, and storage boxes.

3. Holiday Inn Express & Suites Perryville by IHG

Perryville

$101

$116 total

includes taxes & fees

Nov 1 - Nov 2

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

$80

$86 total

includes taxes & fees

Nov 1 - Nov 2

A modern retail area with a display of local items and snacks.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

5. Tru By Hilton Cape Girardeau

Cape Girardeau

$89

$102 total

includes taxes & fees

Oct 22 - Oct 23

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

A cabin interior with a kitchenette, a ceiling fan, a television, a sofa, and a window with blinds.

A playground with a wooden playhouse, a slide, and two animal-shaped swings.

6. Perryville RV Resort

Perryville

$66

$76 total

includes taxes & fees

Oct 15 - Oct 16

A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

A reception area with a blue couch, a wooden table with a vase of flowers, and a reception desk with a digital screen.

A swimming pool with a metal ladder, a Days Inn sign, and a blue water tower in the background.

A kitchen with wooden cabinets, a dining area with a table and chairs, and various kitchen appliances.

7. Days Inn by Wyndham Perryville

Perryville

$68

$77 total

includes taxes & fees

Oct 15 - Oct 16

A lobby with a TV, framed pictures, a plant, and patterned chairs.

A hotel room with a desk, a television, a coffee maker, a chair, and a window with curtains.

A hotel reception desk with a sign that reads "Quality by Choice Hotels."

A hotel room with a large bathtub, a bed with two pillows, a nightstand, and a wall-mounted lamp.

8. Quality Inn Perryville I-55

Perryville

$64

$73 total

includes taxes & fees

Nov 3 - Nov 4

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A building with a sign that reads "The Atrium Boutique Hotel".

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

9. The Atrium - A Boutique Hotel

Perryville

$88

$101 total

includes taxes & fees

Oct 15 - Oct 16

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

10. Comfort Suites Jackson-Cape Girardeau

Jackson

$76

$82 total

includes taxes & fees

Nov 3 - Nov 4

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

11. Town House Inn

Jackson

$71

$77 total

includes taxes & fees

Oct 15 - Oct 16

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

12. Quality Inn Cape Girardeau North

Cape Girardeau

$59

$67 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

A hallway with exposed brick walls, wooden flooring, and a white door.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

13. Urban Lofts

Perryville

$224

$338 total

includes taxes & fees

Oct 15 - Oct 16

A modern kitchen with stainless steel appliances, a large window, and a green cabinet.

A wooden interior with a dining area, staircase, and a television mounted on the wall.

A kitchen with a large black sink, a window with a view of trees, and a microwave on the counter.

A two-story building with a balcony, a front door with a wreath, and a sign indicating a restaurant.

14. The Mediterranean House 1858

Perryville

$404

$697 total

includes taxes & fees

Oct 15 - Oct 16

View all properties

Go beyond your typical stay in Old Appleton

Check out reviews of Old Appleton hotels guests love

Drury Inn & Suites Jackson MO

Jackson

10/10 Exceptional

Nicole

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

10/10 Exceptional

Alexandra

Super 8 by Wyndham Perryville

Perryville

10/10 Exceptional

DAN

Urban Lofts

Perryville

10/10 Exceptional

Gregory

Days Inn by Wyndham Perryville

Perryville

10/10 Exceptional

Anonymous traveler

Town House Inn

Jackson

10/10 Exceptional

larry

Frequently Asked Questions

Can I book a refundable hotel in Old Appleton?

If you're looking for the flexibility to change your travel plans to Old Appleton, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Old Appleton be like during my visit?

The warmest months in Old Appleton are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 40°F. The rainiest months are April and March.

Why should I book my Old Appleton hotel through Hotels.com?

There are plenty of reasons to book your Old Appleton travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.