Hotels in São Tomé

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Where to stay in São Tomé?

A covered walkway with a green carpet, flanked by walls with climbing plants and red flowers.

A bed with white bedding and a blue blanket, a small black stool, and a white wall with a blue panel.

A building with a concrete staircase leading to a door, surrounded by potted plants and a flowering vine.

A building with a stone facade and a closed garage door.

1. Pousada Santo Mel

São Tomé

$17

$18 total

includes taxes & fees

Sep 30 - Oct 1

A hotel room with a desk, a bed, a TV mounted on the wall, and a window with a view of a cityscape.

A multi-story building with a glass facade, a visible storefront, and a street with parked cars.

A bathroom with a glass shower enclosure, a toilet, a sink, and a mirror.

A hotel room with two single beds, wooden wardrobe, and a small shelf with toiletries.

2. Hotel Santa Rita

Santa Cruz

$52

$54 total

includes taxes & fees

Oct 1 - Oct 2

A building entrance with a marble facade, a reception area, and a staircase leading inside.

A hotel room with two beds, one larger and one smaller, both with white linens. There is a wooden wardrobe and an air conditioning unit mounted on the wall.

3. Hotel Imperial

Santa Cruz

$34

$35 total

includes taxes & fees

Oct 3 - Oct 4

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Go beyond your typical stay in São Tomé

Frequently Asked Questions

What accommodations do travelers recommend in São Tomé?

Guests like Pousada Santo Mel.

Can I book refundable hotels in São Tomé?

If you need the flexibility to change your travel plans to São Tomé, most hotels offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in São Tomé be like during my visit?

São Tomé is a great place to visit to enjoy the sunshine any time of year with an average temp of 75°F.

Why should I book my São Tomé accommodation with Hotels.com?

There are lots of reasons to book your São Tomé trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.