Hotels in São Francisco

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Where to stay in São Francisco?

A modern hotel room with a balcony overlooking a body of water, a hanging chair, and a sofa.

A buffet setup with various food items and a dining area with chairs and tables.

A hotel room with two beds, a bedside table with a lamp, a mirror, and an air conditioning unit.

A modern hotel with a prominent 'DM' sign, multiple floors, and a well-lit entrance.

1. DM Hotel

Propria

$53

$56 total

includes taxes & fees

Oct 7 - Oct 8

A modern hotel with a prominent sign reading "HOTEL ROCHEDO".

A reception area with a curved desk, a large wall-mounted screen displaying a mountain landscape, and a modern ceiling design with recessed lighting.

A modern outdoor pool area with tiled flooring, a rectangular pool, and various potted plants.

A buffet with various food items and beverages.

2. HOTEL ROCHEDO

Penedo

$57

$60 total

includes taxes & fees

Oct 15 - Oct 16

A building with a balcony, a sign reading 'Vila do Penedo,' and a sign for 'Port Stylios.'

A room with a reception desk, framed pictures on the wall, a round glass table, and wooden chairs with cushions.

A covered outdoor seating area with tables and chairs, a tiled floor, and a mural on the wall.

A sunset over a body of water with a distant power line tower.

3. Pousada Vila do Penedo

Penedo

$37

$39 total

includes taxes & fees

Oct 12 - Oct 13

A small wooden structure with a covered patio, a chair, and a table.

A calm pond with a wooden walkway and a tree in the center.

A dining area with brick walls, white furniture, and colorful artwork.

4. Pousada Vida de Rio

Santana do Sao Francisco

$148

$155 total

includes taxes & fees

Oct 8 - Oct 9

A buffet with various fruits and beverages.

A workspace with a laptop, a small statue, and a potted plant on a brown desk.

A hallway with hanging planters and a decorative pumpkin sculpture.

A hotel room with two beds, a TV, and an air conditioning unit.

5. Hotel Encantos De Penedo

Penedo

$55

$58 total

includes taxes & fees

Oct 8 - Oct 9

View all properties

Go beyond your typical stay in São Francisco

Frequently Asked Questions

Can I book a refundable hotel in São Francisco?

If you want the flexibility to change your plans to São Francisco, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in São Francisco be like during my trip?

São Francisco is a great place to visit any time of year with an average temperature of 74°F during the coldest months.

Why should I book my São Francisco hotel through Hotels.com?

There are lots of reasons to book your São Francisco trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.