Hotels in Byron

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Where to stay in Byron?

America's Stay Inn Stewartville
America's Stay Inn Stewartville
2.5 star property
Stewartville
8.0 out of 10, Very Good, (430 reviews)
  • cleanliness
    Explore Mayo Clinic just 15 minutes away from this convenient Stewartville hotel.
The price is $72
$78 total
includes taxes & fees
Apr 1 - Apr 2
America's Stay Inn Stewartville
Quality Inn near Medical Center
Quality Inn near Medical Center
2.5 star property
Rochester
7.8 out of 10, Good, (850 reviews)
  • cleanliness
    Convenient Mayo Clinic access with free breakfast, parking, and an indoor pool.
The price is $59
$68 total
includes taxes & fees
Mar 30 - Mar 31
Quality Inn near Medical Center
Baymont by Wyndham Kasson Rochester Area
Baymont by Wyndham Kasson Rochester Area
2.5 star property
Kasson
6.6 out of 10, (382 reviews)
  • cleanliness
    Unwind in tranquil Kasson, just a short drive from Rochester's attractions.
The price is $73
$78 total
includes taxes & fees
Mar 30 - Mar 31
Baymont by Wyndham Kasson Rochester Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.2 out of 10, Good, (1,038 reviews)
  • cleanliness
    Convenient location near Mayo Clinic with free daily breakfast and on-site fitness.
The price is $72
$83 total
includes taxes & fees
Apr 19 - Apr 20
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very Good, (1,232 reviews)
  • cleanliness
    Peaceful retreat near Mayo Clinic with serene atmosphere and indoor pool.
The price is $73
$84 total
includes taxes & fees
Mar 29 - Mar 30
AmericInn by Wyndham Rochester Near Mayo Clinic
Spark by Hilton Rochester South
Spark by Hilton Rochester South
3.0 star property
Rochester
9.4 out of 10, Exceptional, (412 reviews)
  • cleanliness
    Cozy lodging near Mayo Clinic with complimentary breakfast and indoor pool access.
The price is $73
$84 total
includes taxes & fees
Mar 31 - Apr 1
Spark by Hilton Rochester South
Sleep Inn & Suites West-Near Medical Center
Sleep Inn & Suites West-Near Medical Center
2.5 star property
Rochester
9.0 out of 10, Wonderful, (615 reviews)
  • cleanliness
    Convenient hotel near Mayo Clinic with indoor pool and complimentary perks.
The price is $89
$102 total
includes taxes & fees
Apr 18 - Apr 19
Sleep Inn & Suites West-Near Medical Center
Country Inn & Suites Rochester South Mayo Clinic
Country Inn & Suites Rochester South Mayo Clinic
3.0 star property
Rochester
8.4 out of 10, Very Good, (1,003 reviews)
  • cleanliness
    A peaceful Mayo Clinic escape with complimentary hot breakfast and tranquil pool area.
The price is $106
$122 total
includes taxes & fees
Mar 26 - Mar 27
Country Inn & Suites Rochester South Mayo Clinic
Hampton Inn & Suites Rochester-North
Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Modern Rochester hotel with Mayo Clinic access and revitalizing pool amenities.
The price is $98
$112 total
includes taxes & fees
Apr 3 - Apr 4
Hampton Inn & Suites Rochester-North
Staybridge Suites Rochester - Commerce Dr NW by IHG
Staybridge Suites Rochester - Commerce Dr NW by IHG
3.0 star property
Rochester
8.8 out of 10, Excellent, (520 reviews)
  • cleanliness
    Spacious suites with indoor pool just minutes from Mayo Clinic medical campuses.
The price is $105
$121 total
includes taxes & fees
Mar 29 - Mar 30
Staybridge Suites Rochester - Commerce Dr NW by IHG
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.4 out of 10, Very Good, (860 reviews)
  • cleanliness
    Ideal hotel for Mayo Clinic visitors, with a convenient location and indoor pool.
The price is $94
$108 total
includes taxes & fees
Mar 29 - Mar 30
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Americas Best Value Inn & Suites Spring Valley
Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very Good, (442 reviews)
  • cleanliness
    Affordable comfort near Rochester with fitness center and free breakfast perks.
The price is $86
$95 total
includes taxes & fees
Apr 1 - Apr 2
Americas Best Value Inn & Suites Spring Valley
Baymont by Wyndham Rochester Mayo Clinic Area
Baymont by Wyndham Rochester Mayo Clinic Area
2.5 star property
Rochester
7.0 out of 10, Good, (752 reviews)
The price is $60
$69 total
includes taxes & fees
Mar 30 - Mar 31
Baymont by Wyndham Rochester Mayo Clinic Area
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
Rochester
8.0 out of 10, Very Good, (1,004 reviews)
  • cleanliness
    Serene stay near Mayo Clinic with complimentary morning fare and fitness options.
The price is $65
$75 total
includes taxes & fees
Mar 27 - Mar 28
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Comfort Inn & Suites Rochester South Mayo Clinic
Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,002 reviews)
  • cleanliness
    Stay minutes from Rochester airport with a rejuvenating pool and hot tub.
The price is $77
$88 total
includes taxes & fees
Apr 22 - Apr 23
Comfort Inn & Suites Rochester South Mayo Clinic
Comfort Inn & Suites West - Medical Center
Comfort Inn & Suites West - Medical Center
3.0 star property
Rochester
9.0 out of 10, Wonderful, (586 reviews)
  • cleanliness
    Stay minutes from Mayo Clinic with indoor pool and fitness center access.
The price is $88
$102 total
includes taxes & fees
Apr 19 - Apr 20
Comfort Inn & Suites West - Medical Center
Motel 6 Rochester, MN
Motel 6 Rochester, MN
2.0 star property
Rochester
5.8 out of 10, (413 reviews)
  • cleanliness
    Just 5 minutes from Mayo Clinic, offering convenient lodging for medical visits.
The price is $55
$63 total
includes taxes & fees
Mar 25 - Mar 26
Motel 6 Rochester, MN
Country Inn & Suites by Radisson, Rochester, MN
Country Inn & Suites by Radisson, Rochester, MN
2.5 star property
Rochester
7.4 out of 10, Good, (1,001 reviews)
  • cleanliness
    Central hotel near Mayo Clinic offers peaceful rooms and free perks for the weary.
The price is $67
$77 total
includes taxes & fees
Mar 29 - Mar 30
Country Inn & Suites by Radisson, Rochester, MN
Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,005 reviews)
  • cleanliness
    Peaceful hotel near Mayo Clinic with indoor pool and daily complimentary breakfast.
The price is $86
$99 total
includes taxes & fees
Apr 19 - Apr 20
Hampton Inn Rochester-South
Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,003 reviews)
  • cleanliness
    Modern rooms near Mayo Clinic with indoor pool and free hot breakfast daily.
The price is $93
$107 total
includes taxes & fees
Mar 30 - Mar 31
Holiday Inn Express Rochester South - Mayo Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What hotels do travelers recommend in Byron?
Can I book refundable accommodations in Byron?
If you're looking for the flexibility to change your plans to Byron, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Byron be like during my vacation?
July and August are typically the warmest months in Byron when the average temp is 67°F. January and February are the coldest months when the average temperature is 21°F. June and May are the months with the most rain.
Why should I book my Byron hotel with Hotels.com?
There are lots of reasons to book your Byron trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.