Hotels in Roxana

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Comfort Inn Alton near I-255
Comfort Inn Alton near I-255
2.5 star property
Alton
7.6 out of 10, Good, (542 reviews)
This quiet retreat offers an indoor pool and complimentary buffet breakfast, WiFi, and parking. Located near Robert Wadlow Statue and Gordon F. Moore Community Park, with exceptionally helpful staff to enhance your peaceful stay.
The price is $94
$107 total
includes taxes & fees
May 31 - Jun 1
Comfort Inn Alton near I-255
Best Western Plus Parkway Hotel
Best Western Plus Parkway Hotel
2.5 star property
Alton
8.2 out of 10, Very Good, (1,001 reviews)
Relax in this welcoming Alton hotel where clean rooms and a helpful staff set the tone. Take a refreshing dip in the seasonal outdoor pool, or get your workout in at the fitness center. Enjoy free breakfast, WiFi, and parking before exploring nearby attractions.
The price is $84
$96 total
includes taxes & fees
May 17 - May 18
Best Western Plus Parkway Hotel
Holiday Inn Express and Suites Alton St Louis Area by IHG
Holiday Inn Express and Suites Alton St Louis Area by IHG
2.5 star property
Alton
9.2 out of 10, Wonderful, (188 reviews)
This peaceful hotel offers free WiFi, parking, and daily buffet breakfast. Just 10 minutes from Alton Station and close to Alton Square Mall. Enjoy the 24-hour fitness center after exploring Robert Wadlow Statue nearby.
The price is $131
$149 total
includes taxes & fees
May 10 - May 11
Holiday Inn Express and Suites Alton St Louis Area by IHG
Super 8 by Wyndham Troy IL/St. Louis Area
Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
Troy
8.0 out of 10, Very Good, (1,005 reviews)
Minutes from Bella Vista and Villa Marie wineries, this Troy hotel offers free parking and WiFi. Guests love the helpful staff and clean rooms. Take a refreshing swim in the indoor pool after exploring nearby St. Louis attractions.
The price is $68
$75 total
includes taxes & fees
May 14 - May 15
Super 8 by Wyndham Troy IL/St. Louis Area
Red Lion Inn & Suites Pontoon Beach
Red Lion Inn & Suites Pontoon Beach
2.5 star property
Granite City
7.8 out of 10, Good, (657 reviews)
Surrounded by scenic paths, this Granite City hotel offers complimentary breakfast, WiFi, and parking. Nature enthusiasts appreciate the nearby hiking and biking trails, while helpful staff ensure a comfortable stay near local attractions.
The price is $59
$66 total
includes taxes & fees
May 24 - May 25
Red Lion Inn & Suites Pontoon Beach
Country Hearth Inn & Suites Edwardsville St. Louis
Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
Edwardsville
8.6 out of 10, Excellent, (696 reviews)
Enjoy this welcoming hotel near Edwardsville Arts Center where hiking paths await your exploration. The fitness center keeps you active while free breakfast, WiFi, and parking add extra value to your stay. Friendly staff receive consistent praise from visitors.
The price is $144
$166 total
includes taxes & fees
May 10 - May 11
Country Hearth Inn & Suites Edwardsville St. Louis
Hampton Inn & Suites St. Louis/Alton
Hampton Inn & Suites St. Louis/Alton
2.5 star property
Alton
9.0 out of 10, Wonderful, (681 reviews)
Just 9 minutes from Alton Station, this welcoming hotel offers an indoor pool and fitness center. Explore nearby Alton Square Mall and Robert Wadlow Statue, then return to clean, comfortable rooms. Free breakfast, WiFi, and parking enhance your stay.
The price is $139
$159 total
includes taxes & fees
May 31 - Jun 1
Hampton Inn & Suites St. Louis/Alton
Drury Inn & Suites St. Louis Collinsville
Drury Inn & Suites St. Louis Collinsville
3.0 star property
Eastport
9.6 out of 10, Exceptional, (1,003 reviews)
The price is $111
$128 total
includes taxes & fees
May 11 - May 12
Drury Inn & Suites St. Louis Collinsville
Best Western Troy Hotel
Best Western Troy Hotel
2.5 star property
Troy
8.0 out of 10, Very Good, (962 reviews)
This tranquil hotel features an indoor pool and 24-hour fitness center, plus free breakfast, WiFi, and parking. Close to Bella Vista Winery, it earns praise from travelers for clean rooms and helpful staff. Airport is 33 min away.
The price is $89
$99 total
includes taxes & fees
May 10 - May 11
Best Western Troy Hotel
The Great Rivers, an Ascend Collection Hotel
The Great Rivers, an Ascend Collection Hotel
3.0 star property
Alton
7.8 out of 10, Good, (779 reviews)
Located near Alton Station, this hotel offers a refreshing indoor pool and convenient dining at Chapala restaurant. After exploring nearby Robert Wadlow Statue, unwind at the bar or energize in the fitness center. Rooms include microwaves and refrigerators.
The price is $102
$117 total
includes taxes & fees
Jun 1 - Jun 2
The Great Rivers, an Ascend Collection Hotel
Comfort Inn Edwardsville - St. Louis
Comfort Inn Edwardsville - St. Louis
2.5 star property
Edwardsville
8.4 out of 10, Very Good, (843 reviews)
Dive into the indoor pool or energize at the 24-hour fitness center after exploring nearby Vadalabene Center. Free breakfast, WiFi, and parking enhance your stay while the notably helpful staff ensures comfort in this quiet, central location.
The price is $100
$115 total
includes taxes & fees
May 27 - May 28
Comfort Inn Edwardsville - St. Louis
Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport
2.5 star property
St. Ann
9.4 out of 10, Exceptional, (2,981 reviews)
Wake to a complimentary breakfast at this airport-adjacent hotel offering a free shuttle service. Just 10 minutes from Lambert Main Terminal Station, enjoy the seasonal outdoor pool and fitness center after exploring nearby attractions.
The price is $90
$106 total
includes taxes & fees
May 11 - May 12
Pear Tree Inn St. Louis Airport
Holiday Inn Express Troy by IHG
Holiday Inn Express Troy by IHG
2.5 star property
Troy
9.4 out of 10, Exceptional, (767 reviews)
Embrace comfort at this Troy hotel where an indoor pool welcomes morning swimmers. The fitness center keeps routines on track while free breakfast, WiFi, and parking add value. Clean rooms with refrigerators and microwaves make your stay convenient.
The price is $116
$129 total
includes taxes & fees
May 26 - May 27
Holiday Inn Express Troy by IHG
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
O'Fallon
9.6 out of 10, Exceptional, (1,003 reviews)
Splash into comfort at this O'Fallon retreat offering both indoor and outdoor pools. Located near O'Fallon Family Sports Park and St. Clair Bowl, this hotel combines fitness facilities with traveler-praised breakfast and helpful staff.
The price is $106
$123 total
includes taxes & fees
May 17 - May 18
Drury Inn & Suites St. Louis O'Fallon, IL
Super 8 by Wyndham O'Fallon
Super 8 by Wyndham O'Fallon
2.0 star property
O'Fallon
6.8 out of 10, (1,004 reviews)
Stay at this O'Fallon hotel with friendly staff just minutes from St. Louis. Enjoy free breakfast, WiFi, and parking, plus access to a fitness center and seasonal outdoor pool. Nearby attractions include O'Fallon Family Sports Park.
The price is $58
$66 total
includes taxes & fees
May 25 - May 26
Super 8 by Wyndham O'Fallon
Best Western Plus Pontoon Beach
Best Western Plus Pontoon Beach
3.0 star property
Granite City
8.6 out of 10, Excellent, (852 reviews)
The price is $99
$110 total
includes taxes & fees
May 10 - May 11
Best Western Plus Pontoon Beach
Comfort Inn & Suites Saint Louis Lafayette Square
Comfort Inn & Suites Saint Louis Lafayette Square
2.5 star property
The Gate
8.0 out of 10, Very Good, (318 reviews)
Wake up to a complimentary buffet breakfast at this quiet, highway-accessible hotel. Just a 5-minute drive from St. Louis Union Station and Busch Stadium, with fitness center access and convenient proximity to St. Louis University and Enterprise Center.
The price is $117
$136 total
includes taxes & fees
May 27 - May 28
Comfort Inn & Suites Saint Louis Lafayette Square
Red Roof Inn St Louis - Troy, IL
Red Roof Inn St Louis - Troy, IL
2.0 star property
Troy
7.8 out of 10, Good, (1,001 reviews)
Located just outside St. Louis in Troy, IL, this welcoming hotel offers free WiFi, parking, and continental breakfast. Take a refreshing dip in the indoor pool before exploring nearby Bella Vista and Villa Marie wineries. Clean rooms and helpful staff ensure a comfortable visit.
The price is $72
$80 total
includes taxes & fees
May 13 - May 14
Red Roof Inn St Louis - Troy, IL
Best Western St. Louis Airport North Hotel & Suites
Best Western St. Louis Airport North Hotel & Suites
2.5 star property
Hazelwood
7.4 out of 10, Good, (918 reviews)
This business-friendly hotel near St. Louis Lambert Airport offers a free continental breakfast, WiFi, and parking. A 24-hour fitness center adds value, while the helpful staff ensures a comfortable stay just minutes from local attractions.
The price is $76
$93 total
includes taxes & fees
May 17 - May 18
Best Western St. Louis Airport North Hotel & Suites
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
3.0 star property
Granite City
9.2 out of 10, Wonderful, (508 reviews)
Nestled in Granite City, this hotel welcomes travelers with an indoor pool and fitness center. Just minutes from Lewis and Clark Interpretive Center, guests enjoy free breakfast, WiFi, and parking. The friendly staff receives consistent praise from past visitors.
The price is $112
$124 total
includes taxes & fees
May 25 - May 26
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

Can I book a refundable accommodation in Roxana?
If you want the flexibility to change your plans to Roxana, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Roxana be like during my visit?
July and August are typically the warmest months in Roxana when the average temp is 75°F. January and February are the coldest months when the average temperature is 36°F. May and April are the months with the most rain.
Why should I book my Roxana hotel with Hotels.com?
There are lots of reasons to book your Roxana trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.