Hotels in Vance

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Where to stay in Vance?

A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".

A gym with treadmills, weight machines, and a wall of dumbbells.

A Hampton Inn hotel at night with a well-lit facade and a parking lot in the foreground.

1. Hampton Inn Santee-I-95

Santee

$117

$130 total

includes taxes & fees

Oct 19 - Oct 20

A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

A modern lobby with a blue sofa, teal chairs, and a wooden table.

A hotel room with two beds, a desk, and a large window with a view.

A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.

2. Tru By Hilton Santee

Santee

$101

$112 total

includes taxes & fees

Oct 18 - Oct 19

A patio area with wicker furniture, a stone fire pit, and outdoor seating.

A multi-story hotel with a prominent sign, a covered entrance, and a parking lot.

A modern living room with a stone wall, a flat-screen TV, a fireplace, and a dining area with a round table and chairs.

A reception desk with a wooden panel wall and a circular decorative piece above it.

3. Fairfield Inn & Suites by Marriott Santee

Santee

$139

$154 total

includes taxes & fees

Oct 18 - Oct 19

A water park with a pool, slides, and umbrellas.

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

A modern lounge area with seating, tables, and a fireplace.

A reception desk with a wooden panel backdrop and a neon sign.

4. Holiday Inn Santee by IHG

Santee

$104

$115 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.

A lobby with two leather armchairs, a marble-topped table, and a patterned carpet.

A hotel corridor with blue doors, a covered walkway, and a parking lot in the background.

A spacious dining area with multiple tables and chairs, large windows, and a patterned carpet.

5. Baymont by Wyndham Santee

Santee

$80

$89 total

includes taxes & fees

Oct 12 - Oct 13

A hotel entrance with a sign reading "Best Western PLISS."

A spacious living room with a large window, a ceiling fan, and a vibrant red accent wall.

A modern kitchen with a red accent wall, white cabinetry, and a built-in espresso machine.

A hotel room with two large beds, a wooden headboard, bedside tables with lamps, a wardrobe, and a view of the outdoors through a window.

6. Best Western Plus Santee Inn

Santee

$139

$154 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.

A modern living room with teal and orange chairs, a grey sofa, a fireplace, and a staircase.

A modern living room with a sofa, a red ottoman, a TV mounted on the wall, and a wooden entertainment unit.

A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.

7. Comfort Inn & Suites Santee

Santee

$103

$114 total

includes taxes & fees

Nov 1 - Nov 2

A dining area with multiple tables and chairs, a ceiling fan, and large windows.

A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

A two-story building with a beige facade, large windows, and a central entrance.

8. Super 8 by Wyndham Santee/I-95

Santee

$64

$71 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.

A room with a flat-screen TV mounted on the wall, a small round table with a computer and keyboard, a chair, and a framed picture above the table.

A motel with a brick facade, a covered entrance, and a satellite dish.

A bathroom with a granite countertop, a sink, a mirror, and a light fixture above the mirror.

9. Travelodge by Wyndham Santee

Santee

$64

$71 total

includes taxes & fees

Oct 18 - Oct 19

A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.

A spacious kitchen with a central island, a chandelier, and a sign indicating 'Quality' on the wall.

A hotel room with a flat-screen TV, a desk with a chair, a microwave, and a refrigerator.

A hotel room with a bed, bedside tables, a chair, a desk, and a mirror.

10. Quality Inn & Suites Santee I-95

Santee

$54

$65 total

includes taxes & fees

Nov 1 - Nov 2

A vending machine with various snacks and drinks, including Pepsi, and a water dispenser labeled 'Ice Cubes'.

A small, single-story building with a blue exterior and a sign that reads 'Cypress Landing State Park.'

A hotel lobby with a reception desk, a dining area with tables and chairs, and a view of the outside.

A hotel room with a bed, bedside tables, a desk, a mirror, and a wall-mounted TV.

11. Red Roof Inn Santee

Santee

$63

$70 total

includes taxes & fees

Oct 15 - Oct 16

A tent with a view of a lake and boats, a wooden chair, and a potted plant.

A compact living space with a bunk bed, a kitchenette, and a control panel with a clock.

A modern, two-story mobile home with a metal exterior, large windows, and a visible kitchen area.

A tent with two beds, a small table, and a chair.

12. Bells Marina & Resort

Eutawville

$82

$94 total

includes taxes & fees

Oct 12 - Oct 13

A two-story building with a sign reading "PachTree Inn".

A compact hotel room with a kitchenette, a television, a desk, and a chair.

A clean, well-lit dining area with round tables and chairs, a kitchen in the background, and a decorative leaf on the wall.

A hotel room with two beds, a nightstand, a lamp, a chair, and a painting on the wall.

13. Peach Tree Inn

St. George

$58

$63 total

includes taxes & fees

Oct 12 - Oct 13

A conference room with round tables, black chairs, and white tablecloths.

A gym with treadmills, an elliptical, dumbbells, and a bench.

14. Ramada by Wyndham Santee I-95

Santee

$77

$85 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with two beds, a desk, a chair, a lamp, and a bathroom with a mirror and sink.

A bathroom with a sink, mirror, and a shower area.

A reception area with a counter, framed pictures, and a clock on the wall.

15. Econo Lodge Santee

Santee

$68

$75 total

includes taxes & fees

Nov 4 - Nov 5

A bedroom with a bed, bedside tables, a mirror, a door, and a wall-mounted telephone.

A hotel room with a bed, a round table, two chairs, a window with curtains, and an air conditioning unit.

A motel with a signboard, a parking lot, and a grassy area.

A room with a window overlooking a parking area, a shelf with various snacks, and a chair with a towel.

16. Ashburn Inn Manning I 95

Manning

$62

$69 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with a bed, a black armchair, a round mirror with lights, a black vanity with a sink, and a white towel on the wall.

A bathroom with a textured wall, a round mirror with a light, a black countertop, and a white sink.

A television screen displaying the Hulu interface with the title "Reasonable Doubt" and the text "Season 2 premiere" and "Defense attorney Jax Stewart".

A building with a red roof and a covered entrance area. There are cars parked in front.

17. Starlight Stays

Manning

$68

$75 total

includes taxes & fees

Oct 12 - Oct 13

A buffet with various food items and utensils.

A room with a sofa, a small table, a chair, and a patterned rug.

A reception area with a counter, a clock, a ceiling fan, and a potted plant.

A room with a patterned carpet, two potted plants, a wooden shelf with books, and a door with a sign.

18. Sunset Inn Manning I 95

Summerton

$54

$66 total

includes taxes & fees

Oct 25 - Oct 26

A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

A modern bar area with a stone fireplace, a flat-screen TV, and a coffee station.

A reception area with a wooden reception desk, a welcome mat, a vending machine, and a clock on the wall.

A workspace with two desks, each with a computer monitor, keyboard, and chair.

19. Fairfield Inn by Marriott Orangeburg

Orangeburg

$101

$112 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with a black countertop, white cabinets, and a large window.

A parking lot with several cars, a building with a flat roof, and a sign in the background.

A reception area with a counter, a door leading outside, and a patterned wall.

20. Motel 6 Saint George, SC – I-95

St. George

$62

$69 total

includes taxes & fees

Oct 18 - Oct 19

View all properties

Go beyond your typical stay in Vance

Pet friendly

Pool

Family friendly

Learn more about Vance

The region around Vance is home to attractions such as Lake Marion and Santee Cooper Country Club.

See all hotels in Vance

A river with a dam and a bridge, surrounded by greenery and fields.

Check out reviews of Vance hotels guests love

Baymont by Wyndham Santee

10/10 Excellent

":)"

Tru By Hilton Santee

8/10 Good

"Clean Room. Newer Property."

Travelodge by Wyndham Santee

10/10 Excellent

"Nice bed, water was very hot which is nice, and satellite TV with tons of channels."

Fairfield Inn & Suites by Marriott Santee

10/10 Excellent

"repeat user"

Fairfield Inn by Marriott Orangeburg

8/10 Good

"Staff was so friendly, we got there late and left at 6:00 a.m. and both night and day stops were great. Room was comfortable. Wish the breakfast started a little earlier but the coffee in the lobby was amazing. I haven't had spectacular coffee like that in a Lobby hotel in quite a long time. Felt very safe getting out of the car in the parking lot at 10:00 p.m and leaving early."

Bells Marina & Resort

8/10 Good

"Enjoyed our time there. On a beautiful cove of the lake."

Red Roof Inn St George, SC

10/10 Excellent

"I'm here almost every week for work. I've never had a problem here. Everyone is friendly and provides speedy service when requested."

Frequently asked questions

What hotels do travelers recommend in Vance?

Guests like Tru By Hilton Santee, Baymont by Wyndham Santee and Fairfield Inn & Suites by Marriott Santee.

Can I book a refundable accommodation in Vance?

If you want the flexibility to change your travel plans to Vance, most hotels provide refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Vance be like during my visit?

July and August are typically the warmest months in Vance when the average temp is 79°F. January and February are the coldest months when the average temperature is 52°F. August and July are the months with the most rain.

Why should I book my Vance hotel with Hotels.com?

There are lots of reasons to book your Vance trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

More ways to book

Book Hotels in Vance on Hotels.com