Hotels in Wykoff

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Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very Good, (446 reviews)
Stretch out in Spring Valley at this well-maintained motel offering free continental breakfast, WiFi, and parking. Work out in the fitness center before exploring nearby Masonic Park or Four Daughters Vineyard & Winery. Just 26 minutes from Rochester International Airport.
The price is $85
$94 total
includes taxes & fees
May 24 - May 25
Americas Best Value Inn & Suites Spring Valley

America's Stay Inn Stewartville

America's Stay Inn Stewartville
2.5 star property
Stewartville
8.0 out of 10, Very Good, (444 reviews)
Wake up to a complimentary continental breakfast at this Stewartville hotel before heading to Mayo Clinic, just a short drive away. Clean rooms provide a comfortable retreat after visits to nearby Maple Valley Golf & Country Club.
The price is $67
$72 total
includes taxes & fees
May 24 - May 25
America's Stay Inn Stewartville

Stone Mill Hotel & Suites

Stone Mill Hotel & Suites
3.0 star property
Lanesboro
9.2 out of 10, Wonderful, (677 reviews)
Nestled alongside a scenic golf course, this charming hotel offers complimentary breakfast, WiFi, and parking. Outdoor enthusiasts can explore nearby hiking trails, kayaking spots, and seasonal skiing, while cultural attractions and the praised staff enhance your countryside escape.
The price is $105
$113 total
includes taxes & fees
May 25 - May 26
Stone Mill Hotel & Suites

Country Trails Inn & Suites

Country Trails Inn & Suites
2.0 star property
Preston
9.4 out of 10, Exceptional, (114 reviews)
Unwind at this hotel near Old Barn Resort Course, combining country charm with modern comforts. After a morning swim in the indoor pool, relax in the hot tub. Enjoy free breakfast, WiFi, and parking during your Preston getaway.
The price is $126
$140 total
includes taxes & fees
May 24 - May 25
Country Trails Inn & Suites

Green Gables Inn

Green Gables Inn
2.0 star property
Lanesboro
9.4 out of 10, Exceptional, (82 reviews)
Nestled in Lanesboro with free continental breakfast served each morning, this welcoming inn offers complimentary WiFi and parking. Discover nearby Root River and Sylvan Park during your stay, with convenient access for outdoor adventures.
The price is $122
$130 total
includes taxes & fees
May 26 - May 27
Green Gables Inn

Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,001 reviews)
Conveniently located just 0.9 mi from the airport, with a free shuttle service during limited hours. Unwind in the indoor pool and hot tub after exploring nearby Mayo Clinic. Guests love the helpful staff, clean rooms, and free amenities including breakfast, WiFi, and parking.
The price is $73
$84 total
includes taxes & fees
Jun 21 - Jun 22
Comfort Inn & Suites Rochester South Mayo Clinic

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.4 out of 10, Good, (1,056 reviews)
Situated just a 10-minute drive from Mayo Clinic, this hotel offers a complimentary buffet breakfast each morning. Guests appreciate the spotless rooms, free WiFi, and parking. The fitness center and proximity to local attractions add extra value.
The price is $70
$80 total
includes taxes & fees
May 31 - Jun 1
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.4 out of 10, Exceptional, (482 reviews)
Within 10 minutes of Mayo Clinic, this welcoming Rochester hotel offers free breakfast, WiFi, and parking. Swim in the indoor pool, stay fit at the on-site gym, and experience friendly service that guests consistently praise.
The price is $77
$89 total
includes taxes & fees
Jun 7 - Jun 8
Spark by Hilton Rochester South

Country Lodge inn

Country Lodge inn
2.0 star property
Harmony
9.0 out of 10, Wonderful, (41 reviews)
Discover comfort at this quaint motel in Harmony with free WiFi and parking. Explore nearby Slim's Woodshed and Museum or venture to Niagara Cave. Daily housekeeping ensures a pleasant, hassle-free countryside stay.
The price is $144
$165 total
includes taxes & fees
May 25 - May 26
Country Lodge inn

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very Good, (921 reviews)
Minutes from Mayo Clinic and St. Mary's Campus, this hotel offers free breakfast, parking, and WiFi. Enjoy a swim in the indoor pool, unwind in the hot tub, or grab American cuisine at Wildwood Sports Bar. Nearby restaurants, shops, and attractions await.
The price is $94
$108 total
includes taxes & fees
May 27 - May 28
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,000 reviews)
Unwind in this tranquil retreat just 5 minutes from Mayo Clinic. After enjoying the free breakfast, take a refreshing dip in the indoor pool or relax in the hot tub. The helpful staff, free WiFi, and convenient parking enhance your stay near Apache Mall.
The price is $91
$105 total
includes taxes & fees
Jun 14 - Jun 15
Hampton Inn Rochester-South

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,000 reviews)
Relax at this Rochester hotel just minutes from Mayo Clinic. Wake up to a free hot breakfast, unwind in the indoor pool, or keep up your routine at the fitness center. Clean rooms with fridges and microwaves offer comfort after hospital visits.
The price is $96
$111 total
includes taxes & fees
Jun 7 - Jun 8
Holiday Inn Express Rochester South - Mayo Area by IHG

Birch Hill Suite Rochester – Med City

Birch Hill Suite Rochester – Med City
2.5 star property
Rochester
7.0 out of 10, Good, (41 reviews)
This modern Rochester hotel offers free WiFi and parking, plus a fitness center for health-conscious guests. Located within 10 minutes of Mayo Clinic and Saint Marys Campus, it's also near Marcus Cinema and Olmsted County Fairgrounds.
The price is $64
$74 total
includes taxes & fees
May 24 - May 25
Birch Hill Suite Rochester – Med City

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.0 out of 10, Very Good, (1,331 reviews)
Steps from Mayo Clinic, this tranquil hotel offers an indoor pool and on-site dining at Crooked Pint Ale House. Rooms include microwaves and refrigerators while the quiet environment ensures restful recovery. Free breakfast and parking add convenience.
The price is $76
$88 total
includes taxes & fees
Jun 14 - Jun 15
AmericInn by Wyndham Rochester Near Mayo Clinic

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (985 reviews)
Wake up to a free full breakfast at this quiet hotel just 5 minutes from Mayo Clinic. Enjoy complimentary WiFi and parking, plus a 24-hour fitness center. The helpful staff and convenient location near Olmsted County Fairgrounds make this a peaceful choice.
The price is $72
$83 total
includes taxes & fees
Jun 14 - Jun 15
Econo Lodge Mayo Clinic Area

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (1,002 reviews)
Steps from Rochester Public Library and Shops University Square, this hotel offers peaceful rooms and a rooftop terrace. Enjoy American cuisine at Crave restaurant, grab snacks at the deli, or unwind at the bar after using the fitness center.
The price is $112
$129 total
includes taxes & fees
May 26 - May 27
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester
8.0 out of 10, Very Good, (1,566 reviews)
A serene choice near Mayo Clinic, this Rochester hotel provides peaceful accommodations with free breakfast. Visit the on-site coffee shop after your fitness center workout. Guests consistently praise the helpful staff, clean rooms, and proximity to Plummer Building.
The price is $128
$147 total
includes taxes & fees
May 25 - May 26
Kahler Inn and Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area
2.5 star property
Kutzky Park
8.0 out of 10, Very Good, (1,002 reviews)
Relax in this quiet Rochester retreat featuring 2 indoor pools and a hot tub. Just minutes from Mayo Clinic with free breakfast, WiFi, and parking. Nearby Kutzky Park and Cascade Lake Beach offer outdoor escapes after a busy day.
The price is $84
$97 total
includes taxes & fees
May 24 - May 25
Med City Inn & Suites - Mayo Clinic Area

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester
8.4 out of 10, Very Good, (2,110 reviews)
This historic Rochester hotel offers peaceful rooms near Mayo Clinic and Saint Marys Campus. Enjoy the indoor pool, 2 restaurants with American fare, and 24-hour fitness center. Guests praise the helpful staff and convenient location near Plummer Building.
The price is $127
$146 total
includes taxes & fees
May 24 - May 25
Kahler Grand Hotel

MainStay Suites Rochester South Mayo Clinic

MainStay Suites Rochester South Mayo Clinic
2.5 star property
Rochester
7.2 out of 10, Good, (112 reviews)
This extended-stay hotel offers free WiFi and parking only 10 minutes from Mayo Clinic. Spacious suites provide a home base while you're near major medical facilities, with Marcus Rochester Cinema and Olmsted County Fairgrounds close by.
The price is $59
$68 total
includes taxes & fees
Jun 7 - Jun 8
MainStay Suites Rochester South Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

Can I book a refundable hotel in Wykoff?
If you're looking for the flexibility to change your plans to Wykoff, most accommodations offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Wykoff be like during my visit?
The warmest months in Wykoff are usually July and August with an average temp of 68°F. January and February are the chilliest months when the average temp is 22°F. The rainiest months are June and May.
Why should I book my Wykoff hotel through Hotels.com?
There are plenty of reasons to book your Wykoff travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.