Top 10 Hotels in Prairie City, IA in 2026 (from $51)

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Where to stay in Prairie City?

A compact hotel room with a bed, a small kitchenette, a seating area, and a bathroom with a bathtub.

1. Microtel Inn & Suites by Wyndham Colfax/Newton

Colfax

$72 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with two beds, a bedside table with a lamp, and a framed picture on the wall.

2. Quality Inn Newton at I-80

Newton

$71 total

includes taxes & fees

Nov 20 - Nov 21

A hotel room with two beds, a desk with a computer, a mirror, a window with curtains, and a painting on the wall.

3. Baymont Inn & Suites by Wyndham Newton IA

Newton

$64 total

includes taxes & fees

Nov 16 - Nov 17

A hotel room with two beds, a large window with a landscape view, a bathroom with a mirror and sink, and a blue carpet.

4. Days Inn by Wyndham Newton

Newton

$65 total

includes taxes & fees

Nov 18 - Nov 19

A kitchen area with wooden cabinets, a microwave, a coffee machine, and a refrigerator. There are chairs and a table in the dining area.

5. Super 8 by Wyndham Newton

Newton

$57 total

includes taxes & fees

Nov 15 - Nov 16

A two-story building with a green roof and beige walls, featuring a covered entrance and a flagpole with an American flag.

6. Colfax Inn

Colfax

$62 total

includes taxes & fees

Dec 13 - Dec 14

An indoor swimming pool with tiled walls, wooden ceiling beams, and lounge chairs.

7. Best Western Holiday Manor

Newton

$105 total

includes taxes & fees

Nov 15 - Nov 16

An indoor swimming pool with a wooden ceiling and large windows.

8. AmericInn by Wyndham Newton

Newton

$108 total

includes taxes & fees

Nov 20 - Nov 21

An outdoor seating area with a glass-top fire feature, a sofa, and wicker ottomans.

9. Home2 Suites By Hilton Altoona Des Moines

Altoona

$106 total

includes taxes & fees

Nov 22 - Nov 23

A hotel lobby with a reception desk, seating area, and a large chandelier.

10. Prairie Meadows Hotel

Altoona

$165 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a parking lot.

11. La Quinta by Wyndham Altoona Des Moines

Altoona

$91 total

includes taxes & fees

Nov 15 - Nov 16

A modern bar area with a long counter, multiple bar stools, and hanging pendant lights.

12. Hampton Inn & Suites Altoona-Des Moines

Altoona

$106 total

includes taxes & fees

Nov 22 - Nov 23

A spacious kitchen with a large island, bar stools, and a flat-screen TV mounted on the wall.

13. Cobblestone Inn & Suites - Newton

Newton

$123 total

includes taxes & fees

Nov 15 - Nov 16

A Holiday Inn Express & Suites hotel with a covered entrance and a brick facade.

14. Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG

Altoona

$106 total

includes taxes & fees

Dec 13 - Dec 14

A spacious lobby with a wooden reception desk, a staircase, and a second-floor balcony.

15. Sleep Inn & Suites Pleasant Hill - Des Moines

Pleasant Hill

$67 total

includes taxes & fees

Dec 6 - Dec 7

A hotel reception area with a counter, coffee machine, and various amenities.

16. Comfort Inn Altoona-Des Moines

Altoona

$87 total

includes taxes & fees

Dec 6 - Dec 7

A hotel reception area with a marble counter, a red carpet, and a chair with a patterned cushion.

17. Quality Inn & Suites Altoona - Des Moines

Altoona

$66 total

includes taxes & fees

Dec 6 - Dec 7

A multi-story hotel with a sign reading "Woodspring Suites." It features a covered entrance, multiple windows, and a parking lot.

18. WoodSpring Suites Des Moines Pleasant Hill

Pleasant Hill

$62 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with two beds, a TV, a window with blinds, a framed picture on the wall, and a bedside lamp.

19. My Place Hotel - Altoona/Des Moines, IA

Altoona

$83 total

includes taxes & fees

Dec 13 - Dec 14

A hotel with a reflection in a calm body of water, surrounded by open fields.

20. Fairfield Inn & Suites Des Moines Altoona

Altoona

$123 total

includes taxes & fees

Nov 29 - Nov 30

View all properties

Go beyond your typical stay in Prairie City

Top landmarks in Prairie City

Neal Smith National Wildlife Refuge

10.0/10 (2 reviews)

If museums are on your list of things to see in Prairie City, then you might want to head to Neal Smith National Wildlife Refuge.

See properties

Learn more about Prairie City

The region around Prairie City is home to attractions such as Neal Smith National Wildlife Refuge and Iowa Speedway.

See all hotels in Prairie City

Check out reviews of Prairie City hotels guests love

Home2 Suites By Hilton Altoona Des Moines

Altoona

10/10 Exceptional

holly

Best Western Holiday Manor

Newton

10/10 Exceptional

Henry

Hampton Inn & Suites Altoona-Des Moines

Altoona

10/10 Exceptional

Efrem

La Quinta by Wyndham Altoona Des Moines

Altoona

10/10 Exceptional

BREANNA

AmericInn by Wyndham Newton

Newton

10/10 Exceptional

Donna

Fairfield Inn & Suites Des Moines Altoona

Altoona

10/10 Exceptional

We love this hotel! We've stayed 2-3 times in the last couple of years. This last time was the best, starting with Michelle, who checked us into the hotel. She was so friendly, knowledgeable, and just great in representing the hotel. Our room was fantastic, beds were so comfortable even after a full day at Adventureland. The shower had multiple adjustments, and it had these awesome shampoo, conditioner, and body wash pumps on the wall of the shower - they smelled wonderful! The pool/whirlpool...

Anonymous traveler

A swimming pool with four lounge chairs and a view of trees through large windows.

Holiday Inn Express Des Moines Ankeny by IHG

Ankeny

10/10 Exceptional

Raymond

Cobblestone Hotel & Suites - Knoxville

Knoxville

10/10 Exceptional

Anonymous traveler

Days Inn by Wyndham Newton

Newton

10/10 Exceptional

Kim

A sunlit room with a wooden ceiling, a sofa, two armchairs, a coffee table, and a door with an 'EXIT' sign.

Strawtown Inn & Events

Pella

10/10 Exceptional

Gerrit

A La Quinta hotel with a modern design, featuring a prominent sign, a covered entrance, and a brick facade.

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

Ankeny

10/10 Exceptional

Suzanne

Quality Inn Newton at I-80

Newton

10/10 Exceptional

Shawn

Frequently Asked Questions

Can I book refundable hotels in Prairie City?

If you're looking for the flexibility to change your plans to Prairie City, most properties offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Prairie City be like during my trip?

July and August are typically the warmest months in Prairie City when the average temp is 71°F. January and February are the coldest months when the average temperature is 28°F. May and June are the months with the most rain.

Why should I book my Prairie City hotel with Hotels.com?

There are lots of reasons to book your Prairie City trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.