
Hotels in Brussels
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Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (845)
9.4/10
Exceptional
(845)
cleanliness Comfy spot near Wentzville Flea Market with an indoor pool for year-round swims.
The price is $110
$110
$132 total
includes taxes & fees
Jan 2 - Jan 3, 2026




WoodSpring Suites St Peters-OFallon
WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
9.4 out of 10, Exceptional, (23)
9.4/10
Exceptional
(23)
cleanliness Within a 15-minute drive of Ameristar Casino, enjoy extended stay comfort.
The price is $74
$74
$88 total
includes taxes & fees
Dec 24 - Dec 25




Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1009)
9.0/10
Wonderful
(1009)
cleanliness Enjoy a quiet stay in O'Fallon with indoor swimming and fitness amenities.
The price is $78
$78
$92 total
includes taxes & fees
Jan 15 - Jan 16, 2026




Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1003)
8.0/10
Very Good
(1003)
cleanliness Serene pool and fitness amenities near Ameristar Casino in convenient St. Charles.
The price is $89
$89
$103 total
includes taxes & fees
Jan 1 - Jan 2, 2026




Super 8 by Wyndham Jerseyville
Super 8 by Wyndham Jerseyville
2.0 star property
Jerseyville
8.0 out of 10, Very Good, (332)
8.0/10
Very Good
(332)
cleanliness Take a break at this convenient Jerseyville motel with free breakfast daily.
The price is $82
$82
$91 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Comfort Inn & Suites St. Louis - O'Fallon
Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
O'Fallon
7.6 out of 10, Good, (1002)
7.6/10
Good
(1002)
The price is $78
$78
$92 total
includes taxes & fees
Jan 8 - Jan 9, 2026




Hampton Inn By Hilton St Louis Airport
Hampton Inn By Hilton St Louis Airport
2.5 star property
Woodson Terrace
8.8 out of 10, Excellent, (104)
8.8/10
Excellent
(104)
cleanliness Just minutes from St. Louis airport with 24-hour shuttle for hassle-free travel.
The price is $122
$122
$146 total
includes taxes & fees
Dec 29 - Dec 30




Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
Maryland Heights
7.4 out of 10, Good, (1010)
7.4/10
Good
(1010)
cleanliness Enjoy an airport-close suite with indoor pool and kitchen near Hollywood Casino.
The price is $71
$71
$83 total
includes taxes & fees
Jan 1 - Jan 2, 2026




Economy Inn Wentzville
Economy Inn Wentzville
2.0 star property
Wentzville
6.4 out of 10, (508)
6.4/10
(508)
The price is $60
$60
$68 total
includes taxes & fees
Dec 24 - Dec 25




Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1005)
9.4/10
Exceptional
(1005)
cleanliness Peaceful riverfront hotel with easy access to St. Charles Historic District.
The price is $116
$116
$134 total
includes taxes & fees
Jan 18 - Jan 19, 2026




Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
O'Fallon
8.6 out of 10, Excellent, (842)
8.6/10
Excellent
(842)
cleanliness Comfort near St. Louis with free perks and friendly service to enhance your visit.
The price is $91
$91
$107 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Best Western Plus Parkway Hotel
Best Western Plus Parkway Hotel
2.5 star property
Alton
8.2 out of 10, Very Good, (1005)
8.2/10
Very Good
(1005)
cleanliness Seasonal outdoor pool and fitness center just minutes from Alton Square Mall.
The price is $76
$76
$87 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1008)
9.6/10
Exceptional
(1008)
cleanliness Retreat with indoor and outdoor pools near Ameristar Casino in St. Charles.
The price is $115
$115
$133 total
includes taxes & fees
Dec 28 - Dec 29




Hampton Inn St. Louis Wentzville
Hampton Inn St. Louis Wentzville
2.5 star property
Wentzville
9.0 out of 10, Wonderful, (638)
9.0/10
Wonderful
(638)
cleanliness Comfortable rooms near Wentzville Flea Market with indoor pool year-round.
The price is $122
$122
$140 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Super 8 by Wyndham St Charles
Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.0 out of 10, Very Good, (1000)
8.0/10
Very Good
(1000)
cleanliness Peaceful highway oasis with free continental breakfast and casino access nearby.
The price is $76
$76
$87 total
includes taxes & fees
Dec 29 - Dec 30




Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1003)
9.4/10
Exceptional
(1003)
cleanliness Tranquil retreat near Mid Rivers Mall with indoor pool and complimentary breakfast.
The price is $110
$110
$126 total
includes taxes & fees
Dec 28 - Dec 29




Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 star property
Maryland Heights
8.4 out of 10, Very Good, (2220)
8.4/10
Very Good
(2220)
cleanliness Catch the casino action with a quiet escape just minutes from St. Louis attractions.
The price is $130
$130
$166 total
includes taxes & fees
Jan 18 - Jan 19, 2026




Hilton Garden Inn St. Louis/O'Fallon MO
Hilton Garden Inn St. Louis/O'Fallon MO
3.0 star property
O'Fallon
8.8 out of 10, Excellent, (719)
8.8/10
Excellent
(719)
cleanliness Stay minutes from St. Louis in a welcoming O'Fallon retreat with a pool.
The price is $86
$86
$102 total
includes taxes & fees
Dec 29 - Dec 30




Courtyard by Marriott St. Louis Chesterfield
Courtyard by Marriott St. Louis Chesterfield
3.0 star property
Chesterfield
9.0 out of 10, Wonderful, (578)
9.0/10
Wonderful
(578)
cleanliness Enjoy indoor pool and bistro dining near Sky Zone and The Factory in Chesterfield.
The price is $116
$116
$135 total
includes taxes & fees
Jan 3 - Jan 4, 2026




Relax Inn Saint Charles
Relax Inn Saint Charles
2.0 star property
St. Charles
6.6 out of 10, (1000)
6.6/10
(1000)
cleanliness Affordable highway motel with 24-hour service just minutes from Ameristar Casino.
The price is $63
$63
$72 total
includes taxes & fees
Dec 24 - Dec 25
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Brussels
Family friendly
Pet friendly
Check out reviews of Brussels hotels guests love

Hilton Garden Inn St. Louis Airport
10/10 Excellent
"Great hotel staff!"

Hampton Inn By Hilton St Louis Airport
10/10 Excellent
"Clen quiet and friendly staff"

Best Western Plus The Charles Hotel
10/10 Excellent
"Room was very clean and staff were very friendly and courteous"

Best Western Plus St. Louis Airport Hotel
10/10 Excellent
"Yes"

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
10/10 Excellent
"Spacious suite, friendly staff. Check in was easy and everything looked clean"

La Quinta Inn & Suites by Wyndham St. Louis Westport
10/10 Excellent
"Front desk staff very friendly and efficient "

Wingate by Wyndham St. Louis Airport
10/10 Excellent
"Breakfast was good but need some Turkey bacon or turkey sausage, everyone doesn’t eat pork. Overall the breakfast is good. Maybe some chocolate milk"

Motel 6 Hazelwood, MO
10/10 Excellent
"Great stay!"

Hollywood Casino & Hotel St. Louis
10/10 Excellent
"Good and god service "
Frequently asked questions
Can I book a refundable hotel in Brussels?
If you need the flexibility to change your travel plans to Brussels, most properties offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Brussels be like during my visit?
July and August are typically the warmest months in Brussels when the average temp is 75°F. January and February are the coldest months when the average temperature is 37°F. May and April are the months with the most rain.
Why should I book my Brussels hotel with Hotels.com?
There are lots of reasons to book your Brussels trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.