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Hotels in Santa Ana

October 2026
November 2026

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Check prices for these dates

Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Where to stay in Santa Ana?

A swimming pool with lounge chairs, potted plants, and a modern building in the background.
A spacious lobby with a reception desk, seating area, and large windows.
A modern interior with a wooden reception desk, a chair with a unique design, and a neon sign reading 'ONCE 101 BISTRO LATINO'.
A modern living room with a large white sofa, brown leather chairs, a round coffee table, and a large window with a view.

1. Hotel Alameda

Hotel Alameda
Colonia Alameda
$107
$128 total
includes taxes & fees
Oct 1 - Oct 2
Hotel Alameda
A heated outdoor pool with lounge chairs and a restaurant area.
A hotel reception area with a modern design, featuring a marble reception desk, wooden paneling, and a large decorative wall with pottery.
A modern lobby with a large abstract painting, wooden paneling, and seating areas.

2. Comfort Inn Tegucigalpa

Comfort Inn Tegucigalpa
Altos de Miramonte
$140
$167 total
includes taxes & fees
Sep 27 - Sep 28
Comfort Inn Tegucigalpa
A courtyard with a central fountain, surrounded by outdoor seating and red umbrellas.
A lush indoor garden with various plants and a multi-story building in the background.
An indoor atrium with a central seating area, surrounded by lush greenery and string lights. A sign with health and safety instructions is visible.
A hotel lobby with a blue sofa, two glass vases, a Christmas tree, and a reception desk.

3. Hotel Humuya Inn

Hotel Humuya Inn
La Humuya
$70
$84 total
includes taxes & fees
Sep 28 - Sep 29
Hotel Humuya Inn
A modern lobby with a wooden ceiling, a grey sofa, blue chairs, a dining area, and a large abstract painting.
A modern office space with a wooden desk, two chairs, a potted plant, and a decorative wall piece.
A gym with treadmills, an elliptical, and a bench.
A swimming pool with lounge chairs and tables, surrounded by palm trees and a white building.

4. Holiday Inn Express Tegucigalpa by IHG

Holiday Inn Express Tegucigalpa by IHG
Florencia
$110
$142 total
includes taxes & fees
Sep 27 - Sep 28
Holiday Inn Express Tegucigalpa by IHG
A hotel lobby with a reception desk, seating area, and a large clock.
A room with a colorful stained glass ceiling, artwork on the walls, and a reflective floor.
An outdoor pool area with a view of the pool, surrounded by wicker chairs and tables, potted plants, and a flag.
A hotel room with a bed, a red sofa, a glass coffee table, a dining area with a table and chairs, and a view of the city through large windows.

5. Florencia Plaza Hotel

Florencia Plaza Hotel
Florencia
$86
$137 total
includes taxes & fees
Sep 27 - Sep 28
Florencia Plaza Hotel
A spacious, well-lit hallway with a polished marble floor, large windows with decorative ironwork, and a grand chandelier.
A swimming pool with lounge chairs and a building in the background.
A modern living room with a round table and chairs, a sofa, and large windows offering a city view.
A modern living room with a dining area, large windows with a city view, and a flat-screen TV mounted on the wall.

6. Clarion Hotel Real Tegucigalpa

Clarion Hotel Real Tegucigalpa
Colonia Alameda
$111
$132 total
includes taxes & fees
Oct 16 - Oct 17
Clarion Hotel Real Tegucigalpa

7. Aparthotel Guijarros

Aparthotel Guijarros
Lomas del Guijarro Sur
$72
$86 total
includes taxes & fees
Sep 27 - Sep 28
Aparthotel Guijarros
A pool area with a fountain, surrounded by colorful buildings and lush greenery.
A cozy living area with two sofas, a wooden bench, and a potted plant.
A dining area with a glass table surrounded by metal chairs, a sofa, and potted plants.
A beige sofa with two cushions and two wine glasses on a small white table.

8. Hotel Portal del Angel

Hotel Portal del Angel
Tegucigalpa
$77
$92 total
includes taxes & fees
Sep 27 - Sep 28
Hotel Portal del Angel
An outdoor patio area with string lights, tables, chairs, and a central fountain.
A hotel with a modern facade, a prominent entrance, and surrounding greenery.
A spacious restaurant with multiple tables and chairs, large windows offering views of greenery, and a modern ceiling design.
A spacious lobby with large windows, a bar area, and modern furniture.

9. Hotel Honduras Maya

Hotel Honduras Maya
Palmira
$104
$123 total
includes taxes & fees
Sep 27 - Sep 28
Hotel Honduras Maya
A rooftop infinity pool with lounge chairs and a dining area, overlooking a cityscape at dusk.
A multi-story hotel with a modern design, featuring a prominent 'Hyatt Place' sign, a glass atrium, and a view of the cityscape.
A gym with multiple cardio machines, large windows, and a city view.
A modern lobby with a reception desk, seating area, and a large abstract art piece.

10. Hyatt Place Tegucigalpa

Hyatt Place Tegucigalpa
Tegucigalpa
$122
$145 total
includes taxes & fees
Oct 1 - Oct 2
Hyatt Place Tegucigalpa
A room with two beds, a wooden bench, and a painting on the wall.
A room with a brick wall, a window, a colorful blanket, a jar with plant and flowers, and a pair of glasses.
A cozy room with two beds, a wooden bench, a white door, and a brick wall.
A cozy room with a wooden bench, a small table with a vase, and a painting of a tree on the brick wall.

11. Cabañas de la Montaña

Cabañas de la Montaña
Tegucigalpa
$184
$219 total
includes taxes & fees
Sep 27 - Sep 28
Cabañas de la Montaña
An outdoor pool area with seating and a bar.
A hotel lobby with a marble floor, columns, and a reception desk.
A modern hotel room with a wooden ceiling, large windows, a dining area with a glass table, and a living area with a sofa and TV.
A hotel lobby with a check-in counter, a seating area, and a market sign.

12. InterContinental Tegucigalpa at Multiplaza Mall by IHG

InterContinental Tegucigalpa at Multiplaza Mall by IHG
Florencia
$212
$276 total
includes taxes & fees
Oct 1 - Oct 2
InterContinental Tegucigalpa at Multiplaza Mall by IHG
A cozy living room with a stone wall, a fireplace, a television, and two bar stools.
A restaurant with wooden tables and chairs, a brick wall, and a large window.
A room with two beds, each with a patterned bedspread. The room has a brick wall and a wooden door.
A brick building with multiple doors and windows, a paved walkway, and a grassy area.

13. Rincón Ojojona

Rincón Ojojona
Ojojona
$527
$924 total
includes taxes & fees
Sep 27 - Sep 28
Rincón Ojojona
A modern interior with a central seating area, a staircase, and a view of the upper floor.
A spacious lobby with a reception desk, a seating area with a sofa, and a large chandelier.
A bar area with high chairs and a city view.
A hotel room with a large bed, a bedside table with a lamp, a mirror, and a view of the city through the balcony door.

14. Minister Business Hotel

Minister Business Hotel
Florencia
$128
$152 total
includes taxes & fees
Sep 28 - Sep 29
Minister Business Hotel
Outdoor seating with umbrellas, white wicker furniture, and blue cushions.
A narrow hallway with a patterned tile wall, a wooden chair, and multiple hanging planters with various plants.
A modern kitchen with white cabinets, a large island, and a chandelier.
A bedroom with a bed, two bedside tables with lamps, a potted plant, and a painting on the wall.

15. Palmira Hostel

Palmira Hostel
Tegucigalpa
$25
$30 total
includes taxes & fees
Sep 27 - Sep 28
Palmira Hostel
A modern bar area with a central island, bar stools, and a well-stocked bar counter.
A balcony with wicker chairs and a small table, overlooking a cityscape with modern buildings.
A buffet setup with multiple serving stations, each with a dome cover and a spoon.
A swimming pool with a ceiling design, a clock, and a view of the outdoors.

16. Hotel Plaza Juan Carlos

Hotel Plaza Juan Carlos
Palmira
$128
$153 total
includes taxes & fees
Sep 28 - Sep 29
Hotel Plaza Juan Carlos
A spacious lobby with high ceilings, large windows, and a central seating area with sofas and a coffee table.
A multi-story hotel with a green facade, a central entrance with a decorative arch, and several balconies.
A hotel room with a large bed, a bedside telephone, and a window with curtains.
A living room with leather sofas, a glass coffee table, and decorative plants.

17. Hotel El Picacho

Hotel El Picacho
Tegucigalpa
$81
$96 total
includes taxes & fees
Sep 27 - Sep 28
Hotel El Picacho
A hotel lobby with a reception desk, a sofa, and a TV mounted on the wall.
A swimming pool with tiled flooring and metal chairs around it.
A hotel room with a bed, a desk, a chair, a TV, a wardrobe, and a painting on the wall.
A spacious living room with two grey sofas, a wooden coffee table, and a vase with decorative plants.

18. Hotel Mac Arthur

Hotel Mac Arthur
La Leona
$63
$75 total
includes taxes & fees
Sep 27 - Sep 28
Hotel Mac Arthur
A buffet with various food items including bread, pastries, and fruits.
A hotel room with a large bed, a dresser, a desk, and a view of the city.
A hotel room with a large bed, a TV mounted on the wall, and a sliding glass door leading to an outdoor area.
A hallway with wooden doors, wall sconces, and a ceiling light.

19. Hotel Plaza San Martin

Hotel Plaza San Martin
Palmira
$135
$161 total
includes taxes & fees
Sep 27 - Sep 28
Hotel Plaza San Martin
A room with a bed, a small bar area with stools, a television, and a Christmas tree.
A dining area with a long table, chairs, pendant lighting, a fireplace, and artwork on the walls.
A modern interior with a kitchen area, seating, and artwork on the walls.
A balcony with a potted plant, a wicker chair, and a view of the sky and greenery.

20. URITESS INDUSTRIAl APARTAMENTS

URITESS INDUSTRIAl APARTAMENTS
Santa Lucía
$68
$81 total
includes taxes & fees
Sep 29 - Sep 30
URITESS INDUSTRIAl APARTAMENTS
View all properties

Go beyond your typical stay in Santa Ana

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Check out reviews of Santa Ana hotels guests love

A courtyard with a central fountain, surrounded by outdoor seating and red umbrellas.
A lush indoor garden with various plants and a multi-story building in the background.
An indoor atrium with a central seating area, surrounded by lush greenery and string lights. A sign with health and safety instructions is visible.
A hotel lobby with a blue sofa, two glass vases, a Christmas tree, and a reception desk.

Hotel Humuya Inn

Hotel Humuya Inn
La Humuya

10/10 Exceptional

United States
JOANNA
Hotel Humuya Inn
A modern lobby with a wooden ceiling, a grey sofa, blue chairs, a dining area, and a large abstract painting.
A modern office space with a wooden desk, two chairs, a potted plant, and a decorative wall piece.
A gym with treadmills, an elliptical, and a bench.
A swimming pool with lounge chairs and tables, surrounded by palm trees and a white building.

Holiday Inn Express Tegucigalpa by IHG

Holiday Inn Express Tegucigalpa by IHG
Florencia

10/10 Exceptional

United States
Juan
Holiday Inn Express Tegucigalpa by IHG
A heated outdoor pool with lounge chairs and a restaurant area.
A hotel reception area with a modern design, featuring a marble reception desk, wooden paneling, and a large decorative wall with pottery.
A modern lobby with a large abstract painting, wooden paneling, and seating areas.

Comfort Inn Tegucigalpa

Comfort Inn Tegucigalpa
Altos de Miramonte

10/10 Exceptional

United States
Carolina
Comfort Inn Tegucigalpa
A hotel lobby with a reception desk, seating area, and a large clock.
A room with a colorful stained glass ceiling, artwork on the walls, and a reflective floor.
An outdoor pool area with a view of the pool, surrounded by wicker chairs and tables, potted plants, and a flag.
A hotel room with a bed, a red sofa, a glass coffee table, a dining area with a table and chairs, and a view of the city through large windows.

Florencia Plaza Hotel

Florencia Plaza Hotel
Florencia

10/10 Exceptional

United States
Francisco
Florencia Plaza Hotel
A pool area with a fountain, surrounded by colorful buildings and lush greenery.
A cozy living area with two sofas, a wooden bench, and a potted plant.
A dining area with a glass table surrounded by metal chairs, a sofa, and potted plants.
A beige sofa with two cushions and two wine glasses on a small white table.

Hotel Portal del Angel

Hotel Portal del Angel
Tegucigalpa

10/10 Exceptional

United States
Yasmin
Hotel Portal del Angel
A rooftop infinity pool with lounge chairs and a dining area, overlooking a cityscape at dusk.
A multi-story hotel with a modern design, featuring a prominent 'Hyatt Place' sign, a glass atrium, and a view of the cityscape.
A gym with multiple cardio machines, large windows, and a city view.
A modern lobby with a reception desk, seating area, and a large abstract art piece.

Hyatt Place Tegucigalpa

Hyatt Place Tegucigalpa
Tegucigalpa

10/10 Exceptional

United States
Giselle
Hyatt Place Tegucigalpa
An outdoor pool area with seating and a bar.
A hotel lobby with a marble floor, columns, and a reception desk.
A modern hotel room with a wooden ceiling, large windows, a dining area with a glass table, and a living area with a sofa and TV.
A hotel lobby with a check-in counter, a seating area, and a market sign.

InterContinental Tegucigalpa at Multiplaza Mall by IHG

InterContinental Tegucigalpa at Multiplaza Mall by IHG
Florencia

10/10 Exceptional

United States
Marcela
InterContinental Tegucigalpa at Multiplaza Mall by IHG
A modern bar area with a central island, bar stools, and a well-stocked bar counter.
A balcony with wicker chairs and a small table, overlooking a cityscape with modern buildings.
A buffet setup with multiple serving stations, each with a dome cover and a spoon.
A swimming pool with a ceiling design, a clock, and a view of the outdoors.

Hotel Plaza Juan Carlos

Hotel Plaza Juan Carlos
Palmira

10/10 Exceptional

United States
John
Hotel Plaza Juan Carlos
A spacious, well-lit hallway with a polished marble floor, large windows with decorative ironwork, and a grand chandelier.
A swimming pool with lounge chairs and a building in the background.
A modern living room with a round table and chairs, a sofa, and large windows offering a city view.
A modern living room with a dining area, large windows with a city view, and a flat-screen TV mounted on the wall.

Clarion Hotel Real Tegucigalpa

Clarion Hotel Real Tegucigalpa
Colonia Alameda

10/10 Exceptional

United States
Rosy
Clarion Hotel Real Tegucigalpa
An outdoor patio area with string lights, tables, chairs, and a central fountain.
A hotel with a modern facade, a prominent entrance, and surrounding greenery.
A spacious restaurant with multiple tables and chairs, large windows offering views of greenery, and a modern ceiling design.
A spacious lobby with large windows, a bar area, and modern furniture.

Hotel Honduras Maya

Hotel Honduras Maya
Palmira

10/10 Exceptional

United States
JP
Hotel Honduras Maya
A buffet with various food items including bread, pastries, and fruits.
A hotel room with a large bed, a dresser, a desk, and a view of the city.
A hotel room with a large bed, a TV mounted on the wall, and a sliding glass door leading to an outdoor area.
A hallway with wooden doors, wall sconces, and a ceiling light.

Hotel Plaza San Martin

Hotel Plaza San Martin
Palmira

10/10 Exceptional

United States
Anonymous traveler
Hotel Plaza San Martin
A modern interior with a central seating area, a staircase, and a view of the upper floor.
A spacious lobby with a reception desk, a seating area with a sofa, and a large chandelier.
A bar area with high chairs and a city view.
A hotel room with a large bed, a bedside table with a lamp, a mirror, and a view of the city through the balcony door.

Minister Business Hotel

Minister Business Hotel
Florencia

10/10 Exceptional

United States
Mark
Minister Business Hotel
A hotel lobby with a reception desk, a sofa, and a TV mounted on the wall.
A swimming pool with tiled flooring and metal chairs around it.
A hotel room with a bed, a desk, a chair, a TV, a wardrobe, and a painting on the wall.
A spacious living room with two grey sofas, a wooden coffee table, and a vase with decorative plants.

Hotel Mac Arthur

Hotel Mac Arthur
La Leona

10/10 Exceptional

United States
Anonymous traveler
Hotel Mac Arthur
Outdoor seating with umbrellas, white wicker furniture, and blue cushions.
A narrow hallway with a patterned tile wall, a wooden chair, and multiple hanging planters with various plants.
A modern kitchen with white cabinets, a large island, and a chandelier.
A bedroom with a bed, two bedside tables with lamps, a potted plant, and a painting on the wall.

Palmira Hostel

Palmira Hostel
Tegucigalpa

10/10 Exceptional

United States
Caleb
Palmira Hostel
A room with two beds, a wooden bench, and a painting on the wall.
A room with a brick wall, a window, a colorful blanket, a jar with plant and flowers, and a pair of glasses.
A cozy room with two beds, a wooden bench, a white door, and a brick wall.
A cozy room with a wooden bench, a small table with a vase, and a painting of a tree on the brick wall.

Cabañas de la Montaña

Cabañas de la Montaña
Tegucigalpa

10/10 Exceptional

United States
Ramsés
Cabañas de la Montaña
An entrance to a building with a stone archway, a staircase on the left, and a red-lit interior visible through the archway.
An outdoor patio with a tiled floor, a table with chairs, string lights, and potted plants.
A kitchen with a large island, a stove, a microwave, and various kitchen items.
A garden with a brick wall, various trees, and a pathway.

Villa Chelsey

Villa Chelsey
Valle de Angeles

10/10 Exceptional

United States
Ray
Villa Chelsey

Frequently Asked Questions

What accommodations do travelers recommend in Santa Ana?

Guests like Cabañas de la Montaña.

Can I book a refundable hotel in Santa Ana?

If you need the flexibility to change your plans to Santa Ana, most hotels offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Santa Ana be like during my vacation?

The warmest months in Santa Ana are usually April and March with an average temp of 72°F. January and December are the chilliest months when the average temp is 68°F. The rainiest months are May and June.

Why should I book my Santa Ana accommodation with Hotels.com?

There are plenty of reasons to book your Santa Ana travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.