Hotels in San Sisto

Q: What hotels do travelers like in San Sisto?

Guests like La Meridiana Bleisure Hotel , Hotel Sant'Ercolano and Sina Brufani .

Where to?

Dates

November 2026

December 2026

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Where to stay in San Sisto?

A swimming pool with lounge chairs and umbrellas, surrounded by trees and a building with outdoor lighting.

1. Relais dell'Olmo

Perugia

$112 total

includes taxes & fees

Nov 29 - Nov 30

A swimming pool with a waterfall feature, surrounded by a wooden deck and lounge chairs, set against a backdrop of trees and a clear sky.

2. La Meridiana Bleisure Hotel

Perugia

$101 total

includes taxes & fees

Nov 29 - Nov 30

A modern lobby with a central red seating area, a large pillar, and a glass partition.

3. Best Western Hotel Quattrotorri Perugia

Perugia

$115 total

includes taxes & fees

Nov 29 - Nov 30

A poolside area with lounge chairs and umbrellas.

4. Hotel Perugia Plaza

Perugia

$159 total

includes taxes & fees

Nov 26 - Nov 27

A swimming pool with lounge chairs and umbrellas, surrounded by a low wall and string lights.

5. Chocohotel

Perugia

$143 total

includes taxes & fees

Nov 22 - Nov 23

A table with a fruit bowl, teapot, cups, and pastries, set against a scenic mountain backdrop.

6. Hotel Sacro Cuore

Perugia

$91 total

includes taxes & fees

Nov 1 - Nov 2

7. Rosetta Hotel Perugia, Tapestry Collection by Hilton

Old Town Perugia

$178 total

includes taxes & fees

Nov 29 - Nov 30

A balcony with a table set for two, overlooking a historic town with a prominent tower.

8. Hotel Sangallo Palace

Perugia

$148 total

includes taxes & fees

Nov 18 - Nov 19

A person in a white bathrobe standing by a hot tub with a cityscape view in the background.

9. Locanda della Posta - Etruria Collection

Old Town Perugia

$218 total

includes taxes & fees

Nov 27 - Nov 28

A curved red sofa with striped cushions, a small round table, and a large arched window with a view of a forest.

10. Hotel Giò Wine e Jazz Area

Perugia

$125 total

includes taxes & fees

Nov 1 - Nov 2

A rooftop terrace with outdoor seating, a glass enclosure, and a view of the surrounding buildings.

11. Hotel Priori Secret Garden

Old Town Perugia

$176 total

includes taxes & fees

Nov 1 - Nov 2

A pool area with a swimming pool, lounge chairs, and a covered seating area.

12. Posta Donini 1579 UNA Esperienze

Perugia

$167 total

includes taxes & fees

Nov 12 - Nov 13

An indoor swimming pool with arched brick ceilings, lounge chairs, and decorative lanterns.

13. Sina Brufani

Old Town Perugia

$240 total

includes taxes & fees

Nov 28 - Nov 29

An outdoor patio with tables and chairs, overlooking a scenic landscape with trees and a building in the background.

14. Locanda Stella

Perugia

$107 total

includes taxes & fees

Nov 4 - Nov 5

A modern hotel room with a large bed, a small table with a cup and pen, a TV mounted on the wall, and a window with curtains.

15. The Bank Hotel - Etruria Collection

Old Town Perugia

$195 total

includes taxes & fees

Nov 19 - Nov 20

A courtyard with a pool, stone benches, and a view of a hill.

16. TH Perugia - Castello di Monterone

Perugia

$253 total

includes taxes & fees

Nov 6 - Nov 7

A balcony with yellow chairs, a view of a church tower, and a building with antennas.

17. Hotel Sant'Ercolano

Old Town Perugia

$79 total

includes taxes & fees

Nov 23 - Nov 24

A terrace with a table and chairs, potted plants, and a view of distant buildings and mountains.

18. Primavera Mini Hotel

Old Town Perugia

$100 total

includes taxes & fees

Nov 8 - Nov 9

A multi-level outdoor patio with a staircase, seating areas, and potted plants.

19. Residenza il Punto

Perugia

$129 total

includes taxes & fees

Nov 8 - Nov 9

A modern indoor swimming pool with clear glass walls, a blue pool, and a ceiling with a skylight.

20. Perugia Park Hotel

Perugia

$123 total

includes taxes & fees

Nov 29 - Nov 30

View all properties

Go beyond your typical stay in San Sisto

Top landmarks in San Sisto

Perugina Chocolate Factory

8.6/10 (58 reviews)

Perugina Chocolate Factory is 0.5 mi (0.9 km) from central San Sisto, why not stop by during your stay. If you have fun at Perugina Chocolate Factory, you'll love Citta della Domenica and Don Nello Palloni Centro Culturale, both located nearby.

See properties

Check out reviews of San Sisto hotels guests love

Relais dell'Olmo

Perugia

10/10 Exceptional

Anonymous traveler

La Meridiana Bleisure Hotel

Perugia

10/10 Exceptional

Tahmina

Hotel Priori Secret Garden

Old Town Perugia

10/10 Exceptional

Eric

TH Perugia - Castello di Monterone

Perugia

10/10 Exceptional

Castello Di Monterone is a small castle that has outfitted into an 11-12 room hotel. The rooms are small but comfortable with high quality bathrooms, windows, etc. There are lots of little alcoves, inside and out, to hole up in. Great view of Perugia from across the valley, and the city itself is only a few minutes away (although it's one of the more maze-like experiences to try to get into the city center.) Wi-Fi works well, although it's broken into a handful of small zones, owing I...

Mark

Locanda Stella

Perugia

10/10 Exceptional

Telma

Chocohotel

Perugia

10/10 Exceptional

Julie

Hotel Sacro Cuore

Perugia

10/10 Exceptional

The reception and service staff were very friendly, helpful, and kind. The rooms are clean and very spacious. I was delighted to learn that Pope Saint John Paul II slept in this place when it was still a religious site. If you are looking for a luxury hotel, this is not for you. If you want a place that is clean, comfortable and offers peace and tranquility near Perugia, Assisi, Spoleto, Spello, … this place is perfect! It also has parking on site.

Anaisa

Residenza il Punto

Perugia

10/10 Exceptional

Absolutely breathtaking!!! The rooms, the view the service and the location. WOW!! And Salvatore is an absolute gem. We were unsure of how to get there and so he told us to call him when we were nearing the hotel and he stayed with me on the phone and guided our every turn. He waited for us outside so we wouldn’t miss it. Talk about outstanding service. Every room is so charming and tastefully decorated and has the most beautiful views. And just a short and beautiful walk to get to the center....

Gina

Sina Brufani

Old Town Perugia

10/10 Exceptional

Brian

The Bank Hotel - Etruria Collection

Old Town Perugia

10/10 Exceptional

Luis

Hotel Sangallo Palace

Perugia

10/10 Exceptional

Nicole

Posta Donini 1579 UNA Esperienze

Perugia

10/10 Exceptional

Amazing place to stay! It is the little things that make this place one of a kind: like two suitcase stands in the room. The service felt like they were full time career professionals that felt like they really cared about the place and the hospitality. Dinner and breakfast was amazing! Some of the best meals we had in Italy. Loved the old fashion feel to the place - peaceful to walk about the garden and read about the various plants. Wish we had spent more time in the area to be able to...

Anonymous traveler

Hotel Giò Wine e Jazz Area

Perugia

10/10 Exceptional

Della

Frequently Asked Questions

What hotels do travelers like in San Sisto?

Guests like La Meridiana Bleisure Hotel, Hotel Sant'Ercolano and Sina Brufani.

Can I book refundable hotels in San Sisto?

If you want the flexibility to change your plans to San Sisto, most hotels provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in San Sisto be like during my vacation?

The warmest months in San Sisto are usually August and July with an average temp of 72°F. January and February are the chilliest months when the average temp is 44°F. The rainiest months are November and October.

Why should I book my San Sisto accommodation with Hotels.com?

There are plenty of reasons to book your San Sisto travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.